About this data
Pipeline and clinical trial information here comes primarily from ClinicalTrials.gov. A listing on ClinicalTrials.gov means a study has been registered — not that a treatment is proven safe, effective, or FDA-approved. Investigational treatments may never be approved. Who can join a trial is decided only by that trial's own study team.
AZD1656
- Company
- AstraZeneca
- Mechanism
- Mechanism not yet reported
- Route
- Route not yet reported
- Recruiting trials
- None currently listed
Efficacy results: Not yet reported
No recruiting studies currently listed
See all studies for this drugData source: ClinicalTrials.gov · trial data as of Sep 11, 2026
Trial details
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Completed NCT NCT00726427
A Study to Evaluate Safety and Tolerability After Oral Dosing of AZD1656 in Healthy Volunteers
Not yet reported AstraZeneca 32 participants Est. completion 2008-09 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT00741689
A Study to Evaluate Safety and Tolerability After Single Oral Dosing of AZD1656 in Japanese Healthy Volunteers
Not yet reported AstraZeneca 36 participants Est. completion 2008-12 1 site Stand-aloneOther conditions: Healthy VolunteersView official trial listing → -
Completed NCT NCT00747175
A Study to Evaluate Safety, Tolerability and P-Glucose After Multiple Ascending Oral Doses of AZD1656 in Type 2 Diabetes
Not yet reported AstraZeneca 52 participants Est. completion 2009-04 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00768105
To Evaluate Safety and Tolerability After Multiple Oral Doses of AZD1656 in Type 2 Diabetes Patients on Top of Insulin
Not yet reported AstraZeneca 24 participants Est. completion 2009-03 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00774553
To Evaluate Safety and Tolerability After Multiple Oral Doses of AZD1656 in Type 2 Diabetes Patients on Top of Metformin
Not yet reported AstraZeneca 70 participants Est. completion 2010-01 2 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00790153
To Evaluate the Hormonal Response to Low Blood Sugar After a Single Oral Dose of AZD1656 Suspension
Not yet reported AstraZeneca 12 participants Est. completion 2009-02 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT00817271
To Evaluate the Response to Glucagon During Hypoglycemia
Not yet reported AstraZeneca 8 participants Est. completion 2009-04 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00817505
To Evaluate the Bioavailability of a Tablet of AZD1656
Not yet reported AstraZeneca 11 participants Est. completion 2009-09 1 siteOther conditions: Type 1 DiabetesView official trial listing → -
Completed NCT NCT00817778
Study to Assess the Safety and Tolerability After Multiple Oral Doses of AZD1656 in Patients With Type 2 Diabetes Mellitus Treated With Metformin
Not yet reported AstraZeneca 27 participants Est. completion 2009-07 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00819884
To Evaluate 24-hr Glucose After OD vs BD AZD1656
Not yet reported AstraZeneca 36 participants Est. completion 2009-05 1 site Stand-aloneOther conditions: Type II DiabetesView official trial listing → -
Completed NCT NCT00856908
Safety and Tolerability After Four Weeks of Treatment With AZD1656 in Patients With Type 2 Diabetes
Not yet reported AstraZeneca 20 participants Est. completion 2009-08 1 site Stand-aloneOther conditions: Type II DiabetesView official trial listing → -
Completed NCT NCT00916604
To Study Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of AZD1656 in Japanese Type 2 Diabetes Mellitus (T2DM) Patients
Not yet reported AstraZeneca 24 participants Est. completion 2009-10 2 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00960791
Study to Assess the Absorption, Distribution, Metabolism and Excretion of AZD1656 in Type 2 Diabetes Mellitus (T2DM)
Not yet reported AstraZeneca 6 participants Est. completion 2009-09 2 sites Stand-aloneOther conditions: Type II Diabetes MellitusView official trial listing → -
Completed NCT NCT00995787
Safety and Tolerability of AZD1656 in Type 2 Diabetes Mellitus (T2DM) Patients Treated With Metformin and Sulfonylurea
Not yet reported AstraZeneca 75 participants Est. completion 2010-02 1 site Stand-aloneOther conditions: Type II Diabetes MellitusView official trial listing → -
Completed NCT NCT01020123
Evaluate Efficacy, Safety and Tolerability of AZD1656 as Add-on Treatment to Metformin in Type 2 Diabetes Mellitus (TD2M) Patients
Not yet reported AstraZeneca 530 participants Est. completion 2011-02 77 sites Stand-aloneOther conditions: Type II Diabetes MellitusView official trial listing → -
Completed NCT NCT01069926
To Assess the Pharmacokinetics of AZD1656 and Its Metabolite in Type 2 Diabetes Mellitus Patients
Not yet reported AstraZeneca 21 participants Est. completion 2010-10 4 sitesOther conditions: Glucose LoweringView official trial listing → -
Completed NCT NCT01082120
Investigate the Effect of AZD1656 on the Pharmacokinetics of Pioglitazone and Vice Versa in Type 2 Diabetes Mellitus
Not yet reported AstraZeneca 28 participants Est. completion 2010-05 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01083212
To Evaluate the Effect of Gemfibrozil on the Pharmacokinetics and Pharmacodynamics of a Single Dose of AZD1656
Not yet reported AstraZeneca 19 participants Est. completion 2010-06 3 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01095991
Investigate the Effect of AZD1656 on the Pharmacokinetics of Sitagliptin in Patients With Type 2 Diabetes Mellitus
Not yet reported AstraZeneca 12 participants Est. completion 2010-05 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01096940
Study To Assess the Pharmacokinetics of AZD1656 During Coadministration With Simvastatin
Not yet reported AstraZeneca 44 participants Est. completion 2010-08 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01103609
Investigate the Effect of AZD1656 on the Pharmacokinetics and Pharmacodynamics of Warfarin in Type 2 Diabetes Mellitus (T2DM) Patients
Not yet reported AstraZeneca 16 participants Est. completion 2010-08 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01103622
Investigate the Effect of AZD1656 on the Pharmacokinetics of Digoxin in Type 2 Diabetes Mellitus Patients
Not yet reported AstraZeneca 20 participants Est. completion 2010-12 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01152385
Japan Dose Regimen Study of AZD1656 in Japanese Type 2 Diabetes Mellitus Patients
Not yet reported AstraZeneca 224 participants Est. completion 2011-05 3 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01221519
A Relative Bioavailability Study Measuring the Extent and Rate of Absorption of Different Tablet Formulations of AZD1656 in Type 2 Diabetes Mellitus (T2DM) Patients
Not yet reported AstraZeneca 20 participants Est. completion 2011-01 1 site Stand-aloneType 2 diabetes Other conditions: High Blood SugarView official trial listing → -
Completed NCT NCT01221545
A Study to Assess the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics After High Single Ascending Oral Doses of AZD1656 in T2DM Patients
Not yet reported AstraZeneca 24 participants Est. completion 2011-01 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT04516759
AZD1656 in Diabetic Patients Hospitalised With Suspected or Confirmed COVID-19
Not yet reported St George Street Capital 170 participants Est. completion 2021-05-12 30 sites Stand-aloneOther conditions: Covid19View official trial listing → -
Completed NCT NCT05216172
AZD1656 in Transplantation With Diabetes tO PromoTe Immune TOleraNce
Not yet reported Queen Mary University of London 26 participants Est. completion 2022-09-11 1 site Stand-aloneType 2 diabetes Other conditions: Renal Transplant, Kidney Transplant; Complications, End Stage Renal DiseaseView official trial listing →
Efficacy history
Not yet reported.
Safety
Not yet reported.
Sources
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This drug may be investigational and not yet approved for any use. Whether someone can join a clinical trial is determined only by that trial's own study team — On The Pen does not determine eligibility. Information here can change; always confirm current details on the official ClinicalTrials.gov listing or with the sponsor.