About this data
Pipeline and clinical trial information here comes primarily from ClinicalTrials.gov. A listing on ClinicalTrials.gov means a study has been registered — not that a treatment is proven safe, effective, or FDA-approved. Investigational treatments may never be approved. Who can join a trial is decided only by that trial's own study team.
BI 456906
- Company
- Boehringer Ingelheim
- Mechanism
- Mechanism not yet reported
- Route
- Route not yet reported
- Recruiting trials
- 4 recruiting
Efficacy results: Not yet reported
4 recruiting studies currently listed on ClinicalTrials.gov.
Data source: ClinicalTrials.gov · trial data as of Sep 11, 2026
Find a Clinical Trial Near Me
See recruiting studies for BI 456906 and check eligibility with the study team.
Trial details
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Recruiting NCT NCT06632444
LIVERAGE™: A Study to Test Whether Survodutide Helps People With a Liver Disease Called NASH/MASH Who Have Moderate or Advanced Liver Fibrosis
Not yet reported Boehringer Ingelheim 1800 participants Est. completion 2031-12-27 528 sitesMASH Other conditions: Liver FibrosisView official trial listing → -
Recruiting NCT NCT06632457
LIVERAGE™ - Cirrhosis: A Study to Test Whether Survodutide Helps People With a Liver Disease Called NASH/MASH Who Have Cirrhosis
Not yet reported Boehringer Ingelheim 1590 participants Est. completion 2029-06-05 445 sitesMASHView official trial listing → -
Recruiting NCT NCT07754461
A Study to Test Whether Survodutide Helps People With Type 2 Diabetes Control Their Blood Sugar
Not yet reported Boehringer Ingelheim 600 participants Est. completion 2028-05-01 121 sitesType 2 diabetesView official trial listing → -
Recruiting NCT NCT07768813
A Study to Compare How 2 Different Formulations of Survodutide Are Taken up in the Body When Given by Injection in Healthy Men and Women With and Without Overweight or Obesity
Not yet reported Boehringer Ingelheim 44 participants Est. completion 2026-12-22 1 site Stand-aloneOther conditions: Healthy, ObesityView official trial listing → -
Completed NCT NCT03175211
Study to Assess Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of BI 456906 in Healthy Male Volunteers
Not yet reported Boehringer Ingelheim 20 participants Est. completion 2018-02-19 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT03591718
A Study to Test Different Doses of BI 456906 in Patients With Obesity
Not yet reported Boehringer Ingelheim 131 participants Est. completion 2020-04-30 2 sites Stand-aloneOther conditions: ObesityView official trial listing → -
Completed NCT NCT04153929
A Study to Test Whether Different Doses of BI 456906 Are Effective in Treating Adults With Type 2 Diabetes.
Not yet reported Boehringer Ingelheim 413 participants Est. completion 2021-11-04 80 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT04384081
A Study to Test How Different Doses of BI 456906 Are Tolerated in Japanese Men With a Body Mass Index (BMI) Between 23 and 40 kg/m2
Not yet reported Boehringer Ingelheim 37 participants Est. completion 2021-01-20 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT04667377
A Study to Test Whether Different Doses of BI 456906 Help People With Overweight or Obesity to Lose Weight
Not yet reported Boehringer Ingelheim 387 participants Est. completion 2022-10-07 43 sites Stand-aloneOther conditions: ObesityView official trial listing → -
Completed NCT NCT04771273
A Study to Test Safety and Efficacy of Survodutide (BI456906) in Adults With Non-alcoholic Steatohepatitis (NASH) and Fibrosis (F1-F3)
Not yet reported Boehringer Ingelheim 295 participants Est. completion 2023-12-21 154 sitesMASHView official trial listing → -
Active, not recruiting NCT NCT05202353
A Study in People With Obesity to Test the Effects of BI 456906 Compared With Semaglutide on Glucagon Receptor Activity in the Liver
Not yet reported Boehringer Ingelheim 29 participants Est. completion 2027-02-03 1 site Stand-aloneOther conditions: ObesityView official trial listing → -
Completed NCT NCT05296733
A Study to (1) Compare How BI 456906 is Taken up in the Body of Healthy People and People With Liver Problems and (2) Find Out How People With Overweight and Obesity, With and Without Liver Problems, Tolerate Different Doses of BI 456906
Not yet reported Boehringer Ingelheim 82 participants Est. completion 2023-12-29 13 sites Stand-aloneOther conditions: Healthy, Liver Diseases, ObesityView official trial listing → -
Completed NCT NCT05421338
A Study in Healthy Men to Test How BI 456906 is Processed in the Body
Not yet reported Boehringer Ingelheim 6 participants Est. completion 2022-11-17 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT05751226
A Study in People With Overweight or Obesity to Test How Well Different Doses of BI 1820237 Are Tolerated When Given Alone or in Combination With Either Semaglutide or BI 456906
Not yet reported Boehringer Ingelheim 88 participants Est. completion 2024-08-01 1 site Stand-aloneOther conditions: Healthy, ObesityView official trial listing → -
Completed NCT NCT05896384
A Study in Women With Overweight or Obesity to Test Whether Different Doses of BI 456906 Influence the Amount of a Contraceptive in the Blood
Not yet reported Boehringer Ingelheim 32 participants Est. completion 2025-03-26 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT06066515
A Study to Test Whether Survodutide (BI 456906) Helps People Living With Overweight or Obesity Who do Not Have Diabetes to Lose Weight
Not yet reported Boehringer Ingelheim 726 participants Est. completion 2026-02-20 118 sitesOther conditions: ObesityView official trial listing → -
Completed NCT NCT06066528
A Study to Test Whether Survodutide (BI 456906) Helps People Living With Overweight or Obesity Who Also Have Diabetes to Lose Weight
Not yet reported Boehringer Ingelheim 755 participants Est. completion 2026-04-01 143 sitesType 2 diabetes Other conditions: ObesityView official trial listing → -
Completed NCT NCT06077864
A Study to Test the Effect of Survodutide (BI 456906) on Cardiovascular Safety in People With Overweight or Obesity (SYNCHRONIZE™ - CVOT)
Not yet reported Boehringer Ingelheim 5531 participants Est. completion 2026-06-30 539 sitesOther conditions: ObesityView official trial listing → -
Completed NCT NCT06176365
A Study to Test Whether Survodutide Helps Japanese People Living With Obesity Disease
Not yet reported Boehringer Ingelheim 274 participants Est. completion 2025-12-03 28 sitesOther conditions: ObesityView official trial listing → -
Completed NCT NCT06200467
A Study to Test Whether Multiple Doses of BI 456906 Have an Effect on Cardiac Safety in People With Overweight or Obesity
Not yet reported Boehringer Ingelheim 110 participants Est. completion 2025-10-22 1 site Stand-aloneOther conditions: Overweight, ObesityView official trial listing → -
Completed NCT NCT06214741
A Study to Test Whether Survodutide (BI 456906) Helps Chinese People Living With Overweight or Obesity to Lose Weight
Not yet reported Boehringer Ingelheim 307 participants Est. completion 2026-01-28 28 sitesOther conditions: Obesity, OverweightView official trial listing → -
Completed NCT NCT06352411
A Study to Test How BI 456906 is Taken up in the Blood of People With and Without Kidney Problems
Not yet reported Boehringer Ingelheim 42 participants Est. completion 2025-09-16 2 sites Stand-aloneOther conditions: Healthy, Renal ImpairmentView official trial listing → -
Completed NCT NCT06352424
A Study in People With Overweight or Obesity to Test How BI 1820237, BI 456906, or a Combination of Both Affects Brain Activity
Not yet reported Boehringer Ingelheim 23 participants Est. completion 2025-02-24 1 site Stand-aloneOther conditions: ObesityView official trial listing → -
Completed NCT NCT06564441
A Study to Test Whether BI 456906 (Survodutide) Influences the Amount of Bupropion, Caffeine and Midazolam in the Blood in People With Overweight or Obesity
Not yet reported Boehringer Ingelheim 34 participants Est. completion 2026-01-05 1 siteOther conditions: Overweight, ObesityView official trial listing → -
Active, not recruiting NCT NCT06745284
A Study to Test Whether Survodutide Improves How the Body Uses Energy and Breaks Down Fat in People With Obesity
Not yet reported Boehringer Ingelheim 64 participants Est. completion 2027-01-10 2 sitesOther conditions: ObesityView official trial listing → -
Completed NCT NCT06772532
A Study in Healthy People to Compare How 3 Different Formulations of Survodutide Are Taken up in the Body
Not yet reported Boehringer Ingelheim 30 participants Est. completion 2025-06-10 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT07071974
A Study in Healthy People to Compare How 2 Different Formulations of Survodutide Are Taken up in the Body
Not yet reported Boehringer Ingelheim 16 participants Est. completion 2025-10-28 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Not yet recruiting NCT NCT07206290
Albuminuria Reduction Study With Survodutide Treatment in Kidney Disease
Not yet reported University Medical Center Groningen 120 participants Est. completion 2027-11-30 Stand-aloneChronic kidney diseaseView official trial listing → -
Completed NCT NCT07221591
A Study in Healthy People to Compare How 2 Different Formulations of Survodutide Are Taken up by the Body
Not yet reported Boehringer Ingelheim 100 participants Est. completion 2026-07-28 2 sitesOther conditions: HealthyView official trial listing → -
Active, not recruiting NCT NCT07407348
A Study in People With Overweight or Obesity to Compare How 2 Different Formulations of Survodutide Are Taken up by the Body
Not yet reported Boehringer Ingelheim 80 participants Est. completion 2027-03-02 1 siteOther conditions: Healthy, Obesity, OverweightView official trial listing → -
Completed NCT NCT07413913
A Study in Healthy People or Otherwise Healthy With Overweight or Obesity to Compare 2 Formulations of Survodutide Given in Different Ways, Either as a Pre-filled Syringe or a Pen-like Injector
Not yet reported Boehringer Ingelheim 56 participants Est. completion 2026-06-11 1 siteOther conditions: Healthy, ObesityView official trial listing →
Efficacy history
Not yet reported.
Safety
Not yet reported.
Sources
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This drug may be investigational and not yet approved for any use. Whether someone can join a clinical trial is determined only by that trial's own study team — On The Pen does not determine eligibility. Information here can change; always confirm current details on the official ClinicalTrials.gov listing or with the sponsor.
