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About this data Sourced primarily from ClinicalTrials.gov — a listing isn't proof of safety or FDA approval.

Pipeline and clinical trial information here comes primarily from ClinicalTrials.gov. A listing on ClinicalTrials.gov means a study has been registered — not that a treatment is proven safe, effective, or FDA-approved. Investigational treatments may never be approved. Who can join a trial is decided only by that trial's own study team.

Not yet reported

Exendin-9,39

Company
Mayo Clinic
Mechanism
Mechanism not yet reported
Route
Route not yet reported
Recruiting trials
6 recruiting

Efficacy results: Not yet reported

Find a Clinical Trial Near Me

6 recruiting studies currently listed on ClinicalTrials.gov.

Data source: ClinicalTrials.gov · trial data as of Sep 11, 2026

Find a Clinical Trial Near Me

See recruiting studies for Exendin-9,39 and check eligibility with the study team.

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Treatment type

"Added to GLP-1" means the investigational treatment is being studied on top of an existing GLP-1-based therapy.

Your ZIP code is only used to calculate distance to trial sites — it isn't stored.

Trial details
  • Recruiting NCT NCT00992901

    Role of Neural and Hormonal Regulation Factors on Insulin Secretion After Gastric Bypass Surgery

    Not yet reported The University of Texas Health Science Center at San Antonio 160 participants Est. completion 2027-08 2 sites
    Other conditions: Post Bariatricsurgery, Hypoglycemia
    View official trial listing →
  • Recruiting NCT NCT01803451

    Glucagon-like Peptide 1, Glucose Metabolism and Gastric Bypass

    Not yet reported The University of Texas Health Science Center at San Antonio 80 participants Est. completion 2027-08 2 sites
    Other conditions: Post-bariatric Surgery
    View official trial listing →
  • Recruiting NCT NCT02823665

    The Effects of Bariatric Surgeries on Glucose Metabolism

    Not yet reported The University of Texas Health Science Center at San Antonio 200 participants Est. completion 2027-08 2 sites
    Other conditions: Post Bariatric Surgery, Gastric Bypass, Sleeve Gastrectomy, Hypoglycemia After Gastric Bypass
    View official trial listing →
  • Recruiting NCT NCT06967558

    The Role of Islet GLP-1 in the Pathogenesis of Prediabetes

    Not yet reported Mayo Clinic 60 participants Est. completion 2028-03-31 1 site
    Prediabetes
    View official trial listing →
  • Recruiting NCT NCT07019519

    POTS-FLOW: Interplay Between Gut Hormones and Autonomic Postprandial Blood Flow Regulation in Patients With POTS

    Not yet reported University of Copenhagen 30 participants Est. completion 2026-09-30 1 site
    Other conditions: Postural Orthostatic Tachycardia Syndrome (POTS), Healthy
    View official trial listing →
  • Recruiting NCT NCT07806695

    Islet Function in Gestational Diabetes

    Not yet reported Mayo Clinic 90 participants Est. completion 2030-12 1 site
    Other conditions: Gestational Diabetes Mellitus
    View official trial listing →
  • Completed NCT NCT00393445

    Exendin(9-39)Amide as a Glucagon-like Peptide-1 (GLP-1) Receptor Antagonist in Humans

    Not yet reported Ludwig-Maximilians - University of Munich 6 participants Est. completion 2007-05 1 site
    Other conditions: Hyperglycemia
    View official trial listing →
  • Completed NCT NCT00468091

    Effects of Exendin(9-39) on Gastroduodenal Motility

    Not yet reported Ludwig-Maximilians - University of Munich 10 participants Est. completion 2000-09 1 site
    Other conditions: Digestive Physiology, Gastrointestinal Motility, Gastrointestinal Hormones, Glucagon-like Peptide 1, Exendin (9-39)
    View official trial listing →
  • Completed NCT NCT00551590

    Effect of Sitagliptin on Incretin Effect in Patients With Type 2 Diabetes Mellitus

    Not yet reported Ludwig-Maximilians - University of Munich 24 participants Est. completion 2011-09 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00571324

    Effect of Exendin-(9-39) on Glycemic Control in Subjects With Congenital Hyperinsulinism

    Not yet reported, Not yet reported Diva De Leon 9 participants Est. completion 2014-12 1 site
    Other conditions: Congenital Hyperinsulinism
    View official trial listing →
  • Terminated NCT NCT00835328

    Effect of Exendin (9-39) on Glucose Requirements to Maintain Euglycemia

    Not yet reported, Not yet reported Diva De Leon 14 participants Est. completion 2017-01-28 1 site
    Other conditions: Congenital Hyperinsulinism
    View official trial listing →
  • Completed NCT NCT00897676

    Effect of Exendin-(9-39) on Fasting Adaptation and Protein Sensitivity

    Not yet reported, Not yet reported Diva De Leon 17 participants Est. completion 2017-01 1 site
    Other conditions: Congenital Hyperinsulinism
    View official trial listing →
  • Completed NCT NCT00980083

    GLP-1 - Regulatory Mechanism of Postprandial Glycemia

    Not yet reported Ludwig-Maximilians - University of Munich 12 participants Est. completion 2007-12 1 site
    Other conditions: Healthy Subjects, Gastric Emptying
    View official trial listing →
  • Withdrawn NCT NCT01152333

    The Role of GLP-1 in Satiety Perception in Humans

    Not yet reported University of Washington Est. completion 2016-07 1 site
    Other conditions: Appetite Regulation, Obesity
    View official trial listing →
  • Completed NCT NCT01162499

    Role of Glucagon-Like Peptide-1 in Postprandial Hypoglycemia

    Not yet reported Diva De Leon 7 participants Est. completion 2014-12 1 site
    Other conditions: Postprandial Hypoglycemia
    View official trial listing →
  • Completed NCT NCT01181986

    The Study of Exenatide Action on Vessel Function in Type 2 Diabetes and Prediabetes

    Not yet reported Carl T. Hayden VA Medical Center 76 participants Est. completion 2012-12 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01281228

    The Effect of GLP-1 Receptor Activation on Central Reward and Satiety in Obesity and Diabetes

    Not yet reported Amsterdam UMC, location VUmc 48 participants Est. completion 2013-10 1 site
    Type 2 diabetes Other conditions: Diabetes Mellitus, Obesity
    View official trial listing →
  • Completed NCT NCT01363609

    Effects of Glucagon Like Peptide-1(GLP-1) and Liraglutide on Brain Satiety and Reward Circuits and Feeding Behavior in Diabetes

    Not yet reported Amsterdam UMC, location VUmc 50 participants Est. completion 2015-01 1 site
    Type 2 diabetes Other conditions: Obesity
    View official trial listing →
  • Completed NCT NCT01449019

    The Role of Endogenous Glucagon-like Peptide 1 (GLP-1) in Type 2 Diabetes Mellitus (T2DM)

    Not yet reported Ludwig-Maximilians - University of Munich 24 participants Est. completion 2010-07 2 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01579981

    The Importance of GLP-1 in Post RYGB Improvement in Glycaemic Control Type 2 Diabetic Subjects

    Not yet reported Hvidovre University Hospital 9 participants Est. completion 2012-11 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01701973

    Effect of DPP4 Inhibition on Growth Hormone Secretion

    Not yet reported Vanderbilt University 44 participants Est. completion 2017-05 1 site
    Other conditions: Obesity
    View official trial listing →
  • Status unknown NCT NCT01729299

    Ghrelin Effect on Beta Cell Function in Health and Disease

    Not yet reported David Dalessio 30 participants Est. completion 2014-04 2 sites
    Other conditions: Diabetes
    View official trial listing →
  • Status unknown NCT NCT01760772

    Effect of GLP-1 on Postprandial Lipid Metabolism

    Not yet reported David Dalessio 42 participants Est. completion 2015-02 1 site
    Other conditions: Heart Disease
    View official trial listing →
  • Completed NCT NCT01795144

    Incretin Regulation of Insulin Secretion in Monogenic Diabetes

    Not yet reported University of Chicago 10 participants Est. completion 2017-03 1 site
    Other conditions: Monogenic Diabetes
    View official trial listing →
  • Completed NCT NCT01843855

    The Contribution of Incretin Hormones to the Amelioration of Glucose Metabolism After Roux-en-Y Gastric Bypass

    Not yet reported Adrian Vella 12 participants Est. completion 2013-09 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01843881

    The Contribution of Incretin Hormones to Post-prandial Glucose Metabolism After Roux-en-Y Gastric Bypass

    Not yet reported Adrian Vella 20 participants Est. completion 2013-12 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01865760

    Etiology, Assessment and Treatment of Post-gastric Bypass Severe Hypoglycemia

    Not yet reported University of Aarhus 33 participants Est. completion 2016-03 1 site
    Other conditions: Obesity, Hypoglycemia, Surgery
    View official trial listing →
  • Completed NCT NCT01900340

    Intestinal Glucagon-like Peptide-1 (GLP-1) and the Physiological Role in Eating in Humans

    Not yet reported University Hospital, Basel, Switzerland 12 participants Est. completion 2012-12 1 site
    Other conditions: Appetite and General Nutritional Disorders
    View official trial listing →
  • Completed NCT NCT01918566

    The Role of Endogenous GLP-1 (Glycolipoprotein) in Regulating Glucose Stimulated Brain Activity

    Not yet reported University Hospital, Basel, Switzerland 12 participants Est. completion 2013-03 1 site
    Other conditions: Exploratory Behavior
    View official trial listing →
  • Completed NCT NCT02050074

    The Role of Metformin and Colesevelam in Human GLP-1 Secretion

    Not yet reported University Hospital, Gentofte, Copenhagen 12 participants Est. completion 2014-09 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02128581

    A Dose-response of the Effects of Exendin-9,39 on GI Symptoms and Food Intake

    Not yet reported Mayo Clinic 3 participants Est. completion 2019-07 1 site
    Other conditions: Obesity, Diabetes, Roux-en-Y Gastric Bypass
    View official trial listing →
  • Completed NCT NCT02170870

    Gastrointestinal Sensorimotor Dysfunctions in Diabetes Mellitus

    Not yet reported Mayo Clinic 104 participants Est. completion 2017-11-17 1 site
    Other conditions: Dyspepsia, Diabetes Mellitus With Gastrointestinal Symptoms
    View official trial listing →
  • Completed NCT NCT02287285

    Determinants of Diabetes Remission After Gastric Bypass Surgery

    Not yet reported Blandine Laferrere 25 participants Est. completion 2019-07 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02336659

    Influence of Gut Hormones on Food Intake After Roux-en-Y Gastric Bypass Surgery

    Not yet reported Hvidovre University Hospital 12 participants Est. completion 2016-06 1 site
    Other conditions: Severe Obesity
    View official trial listing →
  • Terminated NCT NCT02550145

    Role of GLP-1 in Hyperinsulinemic Hypoglycemia Post-bariatric Surgery

    Not yet reported Tracey McLaughlin 10 participants 1 site
    Other conditions: Hypoglycemia
    View official trial listing →
  • Completed NCT NCT02639130

    GLP-1 Mediating DPP-4 Inhibition in Type 2 Diabetes

    Not yet reported Diabeteszentrum Bad Lauterberg im Harz 67 participants Est. completion 2010-01 1 site
    Type 2 diabetes
    View official trial listing →
  • Withdrawn NCT NCT02697253

    Mechanisms Underlying Predictors of Success From Obesity Surgery

    Not yet reported Icahn School of Medicine at Mount Sinai Est. completion 2021-07-29 1 site
    Other conditions: Obesity
    View official trial listing →
  • Completed NCT NCT02746757

    Glucagon Like Peptide-1 in Remote Ischemic Conditioning

    Not yet reported Karolinska Institutet 12 participants Est. completion 2018-01 1 site
    Other conditions: Healthy Volunteers
    View official trial listing →
  • Completed NCT NCT02771574

    Efficacy, Tolerability and Pharmacokinetics of Subcutaneous Exendin (9-39) in Patients With Post Bariatric Hypoglycemia

    Not yet reported Tracey McLaughlin 19 participants Est. completion 2017-06 1 site
    Other conditions: Post Bariatric Hypoglycemia
    View official trial listing →
  • Completed NCT NCT02779075

    Exendin-9,39 and Satiety After Bariatric Surgery

    Not yet reported Mayo Clinic 29 participants Est. completion 2019-12 1 site
    Other conditions: Obesity
    View official trial listing →
  • Terminated NCT NCT02844907

    Regulation of Insulin Secretion by the GLP-1 Receptor

    Not yet reported VA Office of Research and Development 6 participants Est. completion 2021-12-31 1 site
    Other conditions: Insulin Secretion
    View official trial listing →
  • Completed NCT NCT02971631

    Gastrectomy, Eating Behaviour and GLP-1

    Not yet reported Cambridge University Hospitals NHS Foundation Trust 5 participants Est. completion 2018-09-16 1 site
    Other conditions: Gastric Cancer, Dumping Syndrome
    View official trial listing →
  • Completed NCT NCT02996812

    Evaluation of Single Ascending Doses of Subcutaneous Exendin 9-39 in Patients With Post-Bariatric Hypoglycemia

    Not yet reported Tracey McLaughlin 9 participants Est. completion 2016-08 1 site
    Other conditions: Hyperinsulinemia Hypoglycemia
    View official trial listing →
  • Completed NCT NCT03013296

    Delinieation of GIP's Effects During a Meal in Humans Using GIP Receptor Antagonisation (GA-4)

    Not yet reported University Hospital, Gentofte, Copenhagen 12 participants Est. completion 2018-09 1 site
    Other conditions: Glucose Metabolism Disorders
    View official trial listing →
  • Completed NCT NCT03101930

    Cardiovascular Effects of GLP-1 Receptor Activation

    Not yet reported Vanderbilt University Medical Center 329 participants Est. completion 2021-06-24 1 site
    Prediabetes Other conditions: Obesity
    View official trial listing →
  • Completed NCT NCT03133741

    Inhibition of the Endogenous GIP Response With a GIP Receptor Antagonist

    Not yet reported University Hospital, Gentofte, Copenhagen 18 participants Est. completion 2017-07-01 1 site
    Other conditions: Glucose Metabolism Disorders
    View official trial listing →
  • Completed NCT NCT03241303

    Delineation of the Role of Glucagon-like Peptide-1 Signalling in Relation to Increased Carbohydrate Content in the Distal Small Intestines

    Not yet reported University Hospital, Gentofte, Copenhagen 15 participants Est. completion 2018-01-01 1 site
    Other conditions: Glucose Metabolism Disorders
    View official trial listing →
  • Completed NCT NCT03246451

    The Role of GLP-1 Receptor Signalling in the Glucose-lowering Effect of Metformin in Patients With T2D

    Not yet reported University Hospital, Gentofte, Copenhagen 15 participants Est. completion 2017-12-10 1 site
    Other conditions: Glucose Metabolism Disorders
    View official trial listing →
  • Completed NCT NCT03373435

    Safety and Efficacy of Exendin 9-39 in Patients With Postbariatric Hypoglycemia

    Not yet reported Eiger BioPharmaceuticals 18 participants Est. completion 2019-03-15 5 sites
    Other conditions: Postbariatric Hypoglycemia
    View official trial listing →
  • Completed NCT NCT03950245

    Incretin Hormone Antagonism After Bariatric Surgery

    Not yet reported Hvidovre University Hospital 36 participants Est. completion 2021-04-16 2 sites
    Other conditions: Bariatric Surgery
    View official trial listing →
  • Completed NCT NCT04347252

    Glucagon Regulation of Glucose Metabolism

    Not yet reported David D'Alessio, M.D. 19 participants Est. completion 2021-04-16 1 site
    Other conditions: Insulin Secretion
    View official trial listing →
  • Completed NCT NCT04652479

    Avexitide Safety and Efficacy to Treat Acquired Hyperinsulinemic Hypoglycemia

    Not yet reported Dr. Tracey McLaughlin, MD 25 participants Est. completion 2022-06-30 1 site
    Other conditions: Acquired Hyperinsulinemic Hypoglycemia
    View official trial listing →
  • Completed NCT NCT05177653

    Separate and Combined Extrapancreatic Effects of the Incretin Hormones

    Not yet reported University Hospital, Gentofte, Copenhagen 13 participants Est. completion 2023-03-03 1 site
    Other conditions: Pancreatectomy; Hyperglycemia
    View official trial listing →
  • Status unknown NCT NCT06498063

    The Underlying Mechanisms Regarding the Effect of Glucagon on the Kidneys Will be Investigated in Healthy Males.

    Not yet reported Ali Asmar 10 participants Est. completion 2025-07-31 1 site
    Other conditions: Kidney Diseases
    View official trial listing →
  • Active, not recruiting NCT NCT06747468

    Avexitide for Treatment of Post-Bariatric Hypoglycemia

    Not yet reported Amylyx Pharmaceuticals Inc. 75 participants Est. completion 2027-02 21 sites
    Other conditions: Post Bariatric Hypoglycemia
    View official trial listing →
  • Not yet recruiting NCT NCT06872060

    The Effects of Glucagon on Renal Regional Blood Flow in Humans Measured by Magnetic Resonance.

    Not yet reported Bispebjerg Hospital 10 participants Est. completion 2027-11-01
    Other conditions: Kidney Diseases
    View official trial listing →
  • Not yet recruiting NCT NCT06972407

    The Effect of rs7903146 Genotype on Islet GLP-1 Production in Humans

    Not yet reported Mayo Clinic 80 participants Est. completion 2029-03-01 1 site
    Other conditions: Genetic Predisposition, Type2diabetes
    View official trial listing →
  • Completed NCT NCT07373236

    The Effect of Endogenous GLP-1 on Glucagon Secretion in Type 1 Diabetes

    Not yet reported Asger Lund, MD 12 participants Est. completion 2026-04-09 1 site
    Other conditions: Type 1 Diabetes
    View official trial listing →
  • Available NCT NCT07582874

    An Expanded Access Protocol to Provide Avexitide in Patients With Post-Bariatric Hypoglycemia

    Amylyx Pharmaceuticals Inc. 4 sites
    Other conditions: Post-bariatric Hypoglycemia
    View official trial listing →
Efficacy history

Not yet reported.

Safety

Not yet reported.

Sources
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This drug may be investigational and not yet approved for any use. Whether someone can join a clinical trial is determined only by that trial's own study team — On The Pen does not determine eligibility. Information here can change; always confirm current details on the official ClinicalTrials.gov listing or with the sponsor.