About this data
Pipeline and clinical trial information here comes primarily from ClinicalTrials.gov. A listing on ClinicalTrials.gov means a study has been registered — not that a treatment is proven safe, effective, or FDA-approved. Investigational treatments may never be approved. Who can join a trial is decided only by that trial's own study team.
GZR18
- Company
- Gan & Lee Pharmaceuticals.
- Mechanism
- Mechanism not yet reported
- Route
- Route not yet reported
- Recruiting trials
- 6 recruiting
Efficacy results: Not yet reported
6 recruiting studies currently listed on ClinicalTrials.gov.
Data source: ClinicalTrials.gov · trial data as of Sep 11, 2026
Find a Clinical Trial Near Me
See recruiting studies for GZR18 and check eligibility with the study team.
Trial details
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Recruiting NCT NCT07128888
Study on Gastric Emptying Effect and Drug-Drug Interactions of GZR18 Injection
Not yet reported Gan & Lee Pharmaceuticals. 60 participants Est. completion 2026-07-05 1 site Stand-aloneOther conditions: Obesity or OverweightView official trial listing → -
Recruiting NCT NCT07141030
Study of Pharmacokinetics and Safety of GZR18 Injection in Subjects With Renal Impairment and Normal Renal Function
Not yet reported Gan & Lee Pharmaceuticals. 32 participants Est. completion 2026-03-31 1 site Stand-aloneOther conditions: Obesity/OverweightView official trial listing → -
Recruiting NCT NCT07144098
Study of Pharmacokinetics and Safety of GZR18 Injection in Subjects With Liver Insufficiency and Normal Liver Function
Not yet reported Gan & Lee Pharmaceuticals. 24 participants Est. completion 2027-01-26 1 site Stand-aloneOther conditions: Obesity/OverweightView official trial listing → -
Recruiting NCT NCT07150975
Phase III Clinical Study Comparing the Efficacy and Safety of GZR18 Injection and Semaglutide (Wegovy®) in Adult Obese or Overweight Subjects
Not yet reported Gan & Lee Pharmaceuticals. 420 participants Est. completion 2027-06-30 1 site Stand-aloneOther conditions: Obesity/Overweight in AdultView official trial listing → -
Recruiting NCT NCT07292441
Extension Study of the Phase 3 Clinical Study of GZR18 Injection for Weight Loss
Not yet reported Gan & Lee Pharmaceuticals. 500 participants Est. completion 2027-10 2 sites Stand-aloneOther conditions: Overweight or ObesityView official trial listing → -
Recruiting NCT NCT07355738
Bioequivalence Study of GZR18 Injection Before and After CMC Change
Not yet reported Gan & Lee Pharmaceuticals. 138 participants Est. completion 2026-05-20 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT05328726
Single, Ascending Dose, First Time in Human Study for GZR18 in Healthy Subjects
Not yet reported Gan and Lee Pharmaceuticals, USA 24 participants Est. completion 2023-03-09 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT06256523
A Study of GZR18 Injection in Chinese Adult Patients With Type 2 Diabetes Mellitus (T2DM)
Not yet reported, Not yet reported Gan and Lee Pharmaceuticals, USA 72 participants Est. completion 2023-09-28 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT06256536
A Study of GZR18 Injection in Chinese Obese/Overweight Patients
Not yet reported, Not yet reported Gan and Lee Pharmaceuticals, USA 60 participants Est. completion 2023-10-22 1 site Stand-aloneOther conditions: Obesity, OverweightView official trial listing → -
Status unknown NCT NCT06256549
A Study of GZR18 Injection in Chinese Patients With Type 2 Diabetes Mellitus
Not yet reported Gan and Lee Pharmaceuticals, USA 272 participants Est. completion 2024-07-20 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT06256562
A Study of GZR18 Injection in Obese/Overweight Patients
Not yet reported Gan and Lee Pharmaceuticals, USA 340 participants Est. completion 2024-06-05 1 site Stand-aloneOther conditions: Obesity, OverweightView official trial listing → -
Completed NCT NCT06548945
A Phase I Study of GZR18 Injection in Obese/Overweight Subjects
Not yet reported Gan and Lee Pharmaceuticals, USA 16 participants Est. completion 2023-08-14 1 site Stand-aloneOther conditions: Overweight and ObesityView official trial listing → -
Completed NCT NCT06548997
A Phase I Study of GZR18 Injection in Healthy Subjects
Not yet reported Gan and Lee Pharmaceuticals, USA 57 participants Est. completion 2022-10-20 1 site Stand-aloneType 2 diabetes Other conditions: Overweight and ObesityView official trial listing → -
Status unknown NCT NCT06554054
A Study of GZR18 Tablet in Chinese Healthy Subjects
Not yet reported Gan and Lee Pharmaceuticals, USA 92 participants Est. completion 2024-12-09 1 site Stand-aloneType 2 diabetesView official trial listing → -
Not yet recruiting NCT NCT06670209
A Phase I Clinical Study to Evaluate the Effect of GZR18 Injection on the Pharmacokinetics of Oral Metformin Hydrochloride Tablets in Overweight/Obese Subjects
Not yet reported Gan and Lee Pharmaceuticals, USA 32 participants Est. completion 2025-03-19 Stand-aloneType 2 diabetesView official trial listing → -
Active, not recruiting NCT NCT06728124
A Phase III Clinical Study to Evaluate the Efficacy and Safety of GZR18 Injection in Adult Obese/Overweight Subjects
Not yet reported Gan & Lee Pharmaceuticals. 630 participants Est. completion 2026-05 1 site Stand-aloneOther conditions: Obesity/OverweightView official trial listing → -
Completed NCT NCT06737042
Efficacy and Safety of GZR18 Every 2 Weeks Versus Tirzepatide and Placebo in Obese or Overweight Participants
Not yet reported Gan and Lee Pharmaceuticals, USA 326 participants Est. completion 2026-02-27 20 sites Stand-aloneOther conditions: Obesity and OverweightView official trial listing → -
Active, not recruiting NCT NCT06777238
A Phase III Clinical Study to Evaluate the Efficacy and Safety of GZR18 Injection in Subjects With Type 2 Diabetes Mellitus and Poor Blood Glucose Control by Diet and Exercise
Not yet reported Gan & Lee Pharmaceuticals. 274 participants Est. completion 2027-03-10 1 site Stand-aloneType 2 diabetesView official trial listing → -
Active, not recruiting NCT NCT06778967
A Phase III Clinical Study to Evaluate the Efficacy and Safety of GZR18 Injection in Adult Type 2 Diabetes Mellitus
Not yet reported Gan & Lee Pharmaceuticals. 1100 participants Est. completion 2026-12-11 1 site Stand-aloneType 2 diabetesView official trial listing → -
Not yet recruiting NCT NCT06974487
A Phase I Study to Evaluate the PK and PD Profiles of GZR102 Injection Versus GZR4 Injection and GZR18 Injection Given Separately in Chinese Adult Overweight Subjects
Not yet reported Gan & Lee Pharmaceuticals. 30 participants Est. completion 2025-09-30 1 site Stand-aloneType 2 diabetesView official trial listing → -
Active, not recruiting NCT NCT07055386
A Study to Compare the Efficacy and Safety of GZR102 Injection and GZR18 Injection in Type 2 Diabetes Mellitus
Not yet reported Gan & Lee Pharmaceuticals. 90 participants Est. completion 2027-01 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT07119450
The Study of [14C] GZR18
Not yet reported Gan & Lee Pharmaceuticals. 6 participants Est. completion 2025-08-13 1 site Stand-aloneOther conditions: Overweight, Obese, ObesityView official trial listing → -
Not yet recruiting NCT NCT07493057
Evaluate the Efficacy and Safety of GZR18 Injection in Obese Subjects With Obstructive Sleep Apnea Not Treated With Positive Airway Pressure (PAP) Therapy
Not yet reported Gan & Lee Pharmaceuticals. 140 participants Est. completion 2027-11-14 1 site Stand-aloneObstructive sleep apneaView official trial listing → -
Not yet recruiting NCT NCT07501832
Evaluate the Efficacy and Safety of GZR18 Injection in Obese Subjects With Obstructive Sleep Apnea Receiving Positive Airway Pressure (PAP) Therapy
Not yet reported Gan & Lee Pharmaceuticals. 140 participants Est. completion 2028-09-28 1 site Stand-aloneObstructive sleep apneaView official trial listing → -
Not yet recruiting NCT NCT07622810
BALANCE-OBS: Bofanglutide (GZR18) Versus Semaglutide in Latin American Adults With Overweight or Obesity
Not yet reported Carnot Laboratories 352 participants Est. completion 2027-12 6 sites Stand-aloneOther conditions: Obesity & OverweightView official trial listing → -
Not yet recruiting NCT NCT07628985
BALANCE-DM2 Study of Bofanglutide in Adults With Type 2 Diabetes
Not yet reported Carnot Laboratories 374 participants Est. completion 2027-10 7 sites Stand-aloneType 2 diabetesView official trial listing →
Efficacy history
Not yet reported.
Safety
Not yet reported.
Sources
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