About this data
Pipeline and clinical trial information here comes primarily from ClinicalTrials.gov. A listing on ClinicalTrials.gov means a study has been registered — not that a treatment is proven safe, effective, or FDA-approved. Investigational treatments may never be approved. Who can join a trial is decided only by that trial's own study team.
insulin degludec/liraglutide
- Company
- Novo Nordisk A/S
- Mechanism
- Mechanism not yet reported
- Route
- Route not yet reported
- Recruiting trials
- None currently listed
Efficacy results: Not yet reported
No recruiting studies currently listed
See all studies for this drugData source: ClinicalTrials.gov · trial data as of Sep 11, 2026
Trial details
-
Completed NCT NCT00983021
Safety and Tolerability of NN9068 in Healthy Male Volunteers
Not yet reported Novo Nordisk A/S 24 participants Est. completion 2009-12 1 site Stand-aloneOther conditions: Diabetes, HealthyView official trial listing → -
Completed NCT NCT01319240
Safety and Tolerability of Insulin Degludec/Liraglutide (A3) in Healthy Subjects
Not yet reported Novo Nordisk A/S 24 participants Est. completion 2011-05 1 site Stand-aloneOther conditions: Diabetes, HealthyView official trial listing → -
Completed NCT NCT01336023
Dual Action of Liraglutide and Insulin Degludec in Type 2 Diabetes: A Trial Comparing the Efficacy and Safety of Insulin Degludec/Liraglutide, Insulin Degludec and Liraglutide in Subjects With Type 2 Diabetes
Not yet reported Novo Nordisk A/S 1663 participants Est. completion 2012-11-22 302 sites Stand-aloneType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT01392573
A Trial Comparing the Efficacy and Safety of Insulin Degludec/Liraglutide and Insulin Degludec in Subjects With Type 2 Diabetes
Not yet reported Novo Nordisk A/S 413 participants Est. completion 2012-10-04 86 sites Stand-aloneType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT01618162
The Efficacy of Insulin Degludec/Liraglutide as add-on Therapy in Controlling Glycaemia in Adults With Type 2 Diabetes Inadequately Controlled on Sulphonylurea With or Without Metformin Therapy
Not yet reported Novo Nordisk A/S 435 participants Est. completion 2013-10-23 87 sites Stand-aloneType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT01676116
The Efficacy of Insulin Degludec/Liraglutide in Controlling Glycaemia in Adults With Type 2 Diabetes Inadequately Controlled on GLP-1 Receptor Agonist and OAD Therapy
Not yet reported Novo Nordisk A/S 438 participants Est. completion 2014-03-11 109 sites Stand-aloneType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT01916174
A Trial to Demonstrate Bioequivalence Between Two Insulin Degludec/Liraglutide Formulations, B5 and V2 in Healthy Subjects
Not yet reported Novo Nordisk A/S 50 participants Est. completion 2013-11 1 site Stand-aloneType 2 diabetes Other conditions: Diabetes, HealthyView official trial listing → -
Completed NCT NCT01952145
A Trial Comparing the Efficacy and Safety of Insulin Degludec/Liraglutide Versus Insulin Glargine in Subjects With Type 2 Diabetes Mellitus
Not yet reported Novo Nordisk A/S 557 participants Est. completion 2014-11-04 91 sites Stand-aloneType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT02100475
A Trial Comparing Sequential Addition of Insulin Aspart Versus Further Dose Increase With Insulin Degludec/Liraglutide in Subjects With Type 2 Diabetes Mellitus, Previously Treated With Insulin Degludec/Liraglutide and Metformin and in Need of Further Intensification
Not yet reported Novo Nordisk A/S 31 participants Est. completion 2015-04 60 sites Stand-aloneType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT02298192
A Clinical Trial Comparing Efficacy and Safety of Insulin Degludec/Liraglutide (IDegLira) in Subjects With Type 2 Diabetes Mellitus Using Two Different Titration Algorithms
Not yet reported Novo Nordisk A/S 420 participants Est. completion 2015-12-23 84 sites Stand-aloneType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT02420262
A Clinical Trial Comparing Efficacy and Safety of Insulin Degludec/Liraglutide (IDegLira) Versus Basal-bolus Therapy in Subjects With Type 2 Diabetes Mellitus
Not yet reported Novo Nordisk A/S 506 participants Est. completion 2016-10-05 117 sites Stand-aloneType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT02501161
A 104 Week Clinical Trial Comparing Long Term Glycaemic Control of Insulin Degludec/Liraglutide (IDegLira) Versus Insulin Glargine Therapy in Subjects With Type 2 Diabetes Mellitus
Not yet reported Novo Nordisk A/S 1012 participants Est. completion 2018-10-03 143 sites Stand-aloneType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT02607306
A Trial Comparing the Efficacy and Safety of Insulin Degludec/Liraglutide, Insulin Degludec and Liraglutide in Japanese Subjects With Type 2 Diabetes Mellitus.
Not yet reported Novo Nordisk A/S 819 participants Est. completion 2017-12-22 76 sites Stand-aloneType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT02754817
A Study of the Effectiveness of Xultophy® (Insulin Degludec/Liraglutide) in an Adult Real-world Population With Type 2 Diabetes Mellitus
Novo Nordisk A/S 611 participants Est. completion 2016-10-20 5 sitesType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT02773368
A Clinical Trial Comparing Glycaemic Control and Safety of Insulin Degludec/Liraglutide (IDegLira) Versus Insulin Glargine (IGlar) as add-on Therapy to SGLT2i in Subjects With Type 2 Diabetes Mellitus
Not yet reported Novo Nordisk A/S 420 participants Est. completion 2017-10-23 88 sites Stand-aloneType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT02911948
A Double-blinded Trial Comparing the Efficacy and Safety of Insulin Degludec/Liraglutide and Insulin Degludec Both in Combination With Metformin in Japanese Subjects With Type 2 Diabetes Mellitus Inadequately Controlled With Basal or Pre-mix/Combination Insulin Therapy and Oral Anti-diabetic Drugs
Not yet reported Novo Nordisk A/S 210 participants Est. completion 2017-11-22 38 sites Stand-aloneType 2 diabetes Other conditions: DiabetesView official trial listing → -
Withdrawn NCT NCT03070704
Non-interventional, Post Marketing Surveillance Study of Xultophy™ (Insulin Degludec/Liraglutide) to Evaluate Long Term Safety and Efficacy in Patients With Type 2 Diabetes Mellitus in Routine Clinical Practice in India
Novo Nordisk A/S Est. completion 2019-08-16Type 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT03172494
A Trial Comparing Insulin Degludec/Liraglutide, Insulin Degludec, and Liraglutide in Chinese Subjects With Type 2 Diabetes Inadequately Controlled on Oral Antidiabetic Drugs (OADs)
Not yet reported Novo Nordisk A/S 720 participants Est. completion 2019-07-13 36 sites Stand-aloneType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT03175120
A Trial Comparing Insulin Degludec/Liraglutide and Insulin Degludec in Combination With Metformin in Chinese Subjects With Type 2 Diabetes Mellitus Inadequately Controlled With Basal Insulin Therapy and Metformin With or Without One Other Oral Antidiabetic Drug (OAD)
Not yet reported Novo Nordisk A/S 453 participants Est. completion 2019-04-04 37 sites Stand-aloneType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT03292185
A Trial to Investigate the Single Dose Pharmacokinetics of Insulin Degludec/Liraglutide Compared With Insulin Degludec and Liraglutide in Healthy Chinese Subjects
Not yet reported Novo Nordisk A/S 24 participants Est. completion 2018-01-02 1 site Added to GLP-1Type 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT03737240
IDegLira HIGH Trial
Not yet reported Emory University 145 participants Est. completion 2022-07-08 2 sitesOther conditions: Diabetes MellitusView official trial listing → -
Completed NCT NCT03823339
A Research Study, Looking at How Xultophy® Works in People With Type 2 Diabetes in Local Clinical Practice in United Arab Emirates
Novo Nordisk A/S 300 participants Est. completion 2020-12-14 3 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT03862716
Remission Evaluation of a Metabolic Intervention for Type 2 Diabetes With IDegLira
Not yet reported Population Health Research Institute 159 participants Est. completion 2023-07-31 8 sitesType 2 diabetesView official trial listing → -
Status unknown NCT NCT03959865
GLP-1 REceptor Agonists and Real World EvIdeNce
University of Padova 6000 participants Est. completion 2019-05-31 6 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT04020445
Simplification of Complex Insulin Regimens With Preserving Good Glycemic Control in Type 2 Diabetes
Bekes County Central Hospital 150 participants Est. completion 2022-01-01 1 siteOther conditions: HBA1c, Body Weight, HypoglycemiaView official trial listing → -
Completed NCT NCT04190160
Quality of Life and Fixed-ratio Combination of Insulin Degludec and Liraglutide (iDegLira)
Not yet reported Stefano Rizza 35 participants Est. completion 2021-03-25 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT04196231
Durability of Combination of Insulin and GLP-1 Receptor Agonist or SGLT-2 Inhibitors Versus Basal Bolus Insulin Regimen in Type 2 Diabetes (BEYOND)
Not yet reported University of Campania Luigi Vanvitelli 258 participants Est. completion 2020-10-20 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT04666987
A Research Study Looking at Long-term Blood Sugar Control in People With Type 2 Diabetes Being Treated With Xultophy® in a Real-world Setting in Italy
Novo Nordisk A/S 359 participants Est. completion 2023-02-10 28 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT04838743
GOAL: A Research Study Looking at Long Term Blood Sugar Control in People With Type 2 Diabetes Treated With Xultophy® in Local Clinical Practice in Japan.
Novo Nordisk A/S 244 participants Est. completion 2022-10-26 42 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT04952779
Regulatory Post Marketing Surveillance (rPMS) Study of Xultophy® (Insulin Degludec/Liraglutide) to Evaluate Safety and Effectiveness in Patients With Type 2 Diabetes Mellitus in Routine Clinical Practice in Korea
Novo Nordisk A/S 750 participants Est. completion 2024-12-15 32 sitesType 2 diabetesView official trial listing → -
Active, not recruiting NCT NCT05220917
Comparative Effectiveness and Safety of Four Second Line Pharmacological Strategies in Type 2 Diabetes Study
Brigham and Women's Hospital 781430 participants Est. completion 2027-09-30 1 siteType 2 diabetes Other conditions: Cardiovascular Events, Renal DiseaseView official trial listing → -
Completed NCT NCT05324462
Glycaemic Control and Other Clinical Parameters in Adult Type 2 Diabetes Patients on Basal Insulin Initiating Treatment With IDegLira in Routine Clinical Practice in Colombia
Novo Nordisk A/S 175 participants Est. completion 2022-07-15 6 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT05360537
Effects of Degludec/Liraglutide on Time in Range, Inflammation and Endothelial Function vs Insulin Basal Bolus in Diabetic Inpatients
Not yet reported University of Palermo 100 participants Est. completion 2022-04-20 1 site Added to GLP-1Type 2 diabetesView official trial listing → -
Withdrawn NCT NCT05479591
A Research Study Looking at Blood Sugar Control in People With Type 2 Diabetes Previously Treated With Premix Insulin and Initiating Treatment With Insulin Degludec/Liraglutide (IDegLira) in Local Clinical Practice in Croatia
Novo Nordisk A/S Est. completion 2023-04-30Type 2 diabetesView official trial listing → -
Status unknown NCT NCT05545800
Efficacy and Safety Of Different Regimens In Patients With Type 2 Diabetes Receiving Intensive Insulin Therapy
Not yet reported Xiangya Hospital of Central South University 78 participants Est. completion 2024-06-01 1 siteType 2 diabetesView official trial listing → -
Status unknown NCT NCT05767255
Risk of Hypoglycemia in the Transition From Inpatient to Outpatient Setting. Comparative Study of Basal-bolus Insulin Versus Basal Insulin Plus GLP-1 Analogue
Not yet reported Hospital Universitario San Ignacio 66 participants Est. completion 2023-08-30 1 siteType 2 diabetesView official trial listing → -
Withdrawn NCT NCT06113341
A Research Study in Italy to Understand How the Dose Check App Used With Xultophy® Works in the Treatment of People Living With Type 2 Diabetes
Novo Nordisk A/S Est. completion 2026-03-02 19 sitesType 2 diabetesView official trial listing → -
Status unknown NCT NCT06408532
The Efficacy and Safety of Insulin Degludec/Liraglutide Combination (IDegLira) in Patients With Type 2 Diabetes
Not yet reported Peking University People's Hospital 256 participants Est. completion 2025-02-28Type 2 diabetesView official trial listing → -
Status unknown NCT NCT06449703
A Trial to Investigate the Single Dose Pharmacokinetics of Insulin Degludec/Liraglutide in Healthy Chinese Subjects
Not yet reported Tonghua Dongbao Pharmaceutical Co.,Ltd 44 participants Est. completion 2024-06-16 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Status unknown NCT NCT06559722
A Trial Investigating the Efficacy and Safety of Insulin Degludec/Liraglutide Injection in Subjects With Type 2 Diabetes
Not yet reported Tonghua Dongbao Pharmaceutical Co.,Ltd 510 participants Est. completion 2026-02 Stand-aloneType 2 diabetesView official trial listing →
Efficacy history
Not yet reported.
Safety
Not yet reported.
Sources
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