About this data
Pipeline and clinical trial information here comes primarily from ClinicalTrials.gov. A listing on ClinicalTrials.gov means a study has been registered — not that a treatment is proven safe, effective, or FDA-approved. Investigational treatments may never be approved. Who can join a trial is decided only by that trial's own study team.
Metformin
- Company
- Ziauddin University
- Mechanism
- Mechanism not yet reported
- Route
- Route not yet reported
- Recruiting trials
- 53 recruiting
Efficacy results: Not yet reported
53 recruiting studies currently listed on ClinicalTrials.gov.
Data source: ClinicalTrials.gov · trial data as of Sep 11, 2026
Find a Clinical Trial Near Me
See recruiting studies for Metformin and check eligibility with the study team.
Trial details
-
Recruiting NCT NCT01638676
A Phase I/II Trial of Vemurafenib and Metformin to Melanoma Patients
Not yet reported, Not yet reported University of Louisville 55 participants Est. completion 2027-06 1 siteOther conditions: MelanomaView official trial listing → -
Recruiting NCT NCT02647827
Acupuncture or Metformin for Insulin Resistance in Women With PCOS
Not yet reported Karolinska Institutet 303 participants Est. completion 2026-06 2 sitesOther conditions: Polycystic Ovary Syndrome, Insulin Resistance, HyperandrogenismView official trial listing → -
Recruiting NCT NCT02915198
Investigation of Metformin in Pre-Diabetes on Atherosclerotic Cardiovascular OuTcomes
Not yet reported VA Office of Research and Development 7410 participants Est. completion 2029-09-28 40 sitesOther conditions: Prediabetic State, Atherosclerosis, MetforminView official trial listing → -
Recruiting NCT NCT02947503
Pregnancy Outcomes: Effects of Metformin Study (POEM Study)
Not yet reported Bethesda Diabetes Research Center 500 participants Est. completion 2043-12 4 sitesOther conditions: Gestational Diabetes, Insulin ResistanceView official trial listing → -
Recruiting NCT NCT02969798
Pre-diabetes in Subject With Impaired Fasting Glucose (IFG) and Impaired Glucose Tolerance (IGT)
Not yet reported The University of Texas Health Science Center at San Antonio 700 participants Est. completion 2027-07 1 siteType 2 diabetesPrediabetesView official trial listing → -
Recruiting NCT NCT03424005
A Study Evaluating the Efficacy and Safety of Multiple Treatment Combinations in Patients With Metastatic or Locally Advanced Breast Cancer
Not yet reported, Not yet reported Hoffmann-La Roche 1132 participants Est. completion 2030-09-30 53 sites Stand-aloneOther conditions: Metastatic Breast CancerView official trial listing → -
Recruiting NCT NCT03568630
Blood Markers of Early Pancreas Cancer
University of Nebraska 1250 participants Est. completion 2028-07 1 siteType 2 diabetesPrediabetes Other conditions: Pancreas Cyst, Chronic Pancreatitis, Genetic Predisposition to Disease, Inherited DiseaseView official trial listing → -
Recruiting NCT NCT04670666
Efficacy and Safety of Madalena Association in the Treatment of Type II Diabetes Mellitus
Not yet reported EMS 270 participants Est. completion 2027-06 1 site Stand-aloneType 2 diabetesView official trial listing → -
Recruiting NCT NCT04945148
Oxidative Phosphorylation Targeting In Malignant Glioma Using Metformin Plus Radiotherapy Temozolomide
Not yet reported Hopital Foch 640 participants Est. completion 2028-05 7 sites Stand-aloneOther conditions: Glioblastoma, IDH-wildtypeView official trial listing → -
Recruiting NCT NCT05036226
COAST Therapy in Advanced Solid Tumors and Prostate Cancer
Not yet reported, Not yet reported Medical University of South Carolina 76 participants Est. completion 2028-05-21 1 site Stand-aloneOther conditions: Prostate Cancer Recurrent, Solid Tumor, AdultView official trial listing → -
Recruiting NCT NCT05164263
Real World Safety & Efficacy Experience of Empagliflozin With or Without Metformin in T2DM Patients - EASE Study
Not yet reported Getz Pharma 2000 participants Est. completion 2027-08-31 6 sitesOther conditions: Type II Diabetes Mellitus, Efficacy, Self, Safety IssuesView official trial listing → -
Recruiting NCT NCT05205317
Comparison of the Therapeutic Effects of VR and VR + Metformin in the Treatment of Cesarean Section Scar Defect
Not yet reported Xinhua Hospital, Shanghai Jiao Tong University School of Medicine 100 participants Est. completion 2027-06-30 1 siteOther conditions: DefectView official trial listing → -
Recruiting NCT NCT05230758
Effect of Metformin on Behaviour and the Brain in Children Treated for a Brain Tumour
Not yet reported Donald Mabbott 140 participants Est. completion 2027-11-30 20 sitesOther conditions: Medulloblastoma, Childhood, Cognitive ImpairmentView official trial listing → -
Recruiting NCT NCT05243654
Efficacy and Tolerability of Adjunct Metformin for Multibacillary Leprosy
Not yet reported Oxford University Clinical Research Unit Indonesia 166 participants Est. completion 2026-09-30 6 sites Stand-aloneOther conditions: Leprosy, Leprosy, Multibacillary, Neglected Tropical DiseasesView official trial listing → -
Recruiting NCT NCT05275608
Effects of VLCKD in Metabolic Syndrome
Not yet reported Azienda Ospedaliero Universitaria Maggiore della Carita 40 participants Est. completion 2025-12 1 siteType 2 diabetesMetabolic syndrome Other conditions: Non-alcoholic Fatty Liver Disease, ObesityView official trial listing → -
Recruiting NCT NCT05316935
GnRHa + Letrozole in Non-obese Progestin-insensitive Endometrial Cancer and Atypical Hyperplasia Patients
Not yet reported, Not yet reported Xiaojun Chen 80 participants Est. completion 2028-03-30 2 sites Stand-aloneOther conditions: Endometrial Neoplasms, Atypical Endometrial Hyperplasia, Progesterone ResistanceView official trial listing → -
Recruiting NCT NCT05414409
The Gut Microbiome in Type 1 Diabetes and Mechanism of Metformin Action
Not yet reported Heba M. Ismail 114 participants Est. completion 2027-03-01 1 siteOther conditions: Type 1 Diabetes, ObesityView official trial listing → -
Recruiting NCT NCT05819853
Role of Semaglutide in Restoring Ovulation in Youth and Adults With Polycystic Ovary Syndrome
Not yet reported University of Colorado, Denver 80 participants Est. completion 2028-06-30 1 siteOther conditions: PCOS (Polycystic Ovary Syndrome) of Bilateral Ovaries, ObeseView official trial listing → -
Recruiting NCT NCT05900466
Metformin for Fibromyalgia Symptoms (INFORM Trial)
Not yet reported University of Utah 72 participants Est. completion 2027-03-31 1 siteOther conditions: Fibromyalgia SyndromeView official trial listing → -
Recruiting NCT NCT06044025
A Feasibility Study Evaluating a Role for Maintenance Therapy in Patients With Biochemically Progressive Castration Sensitive Prostate Cancer on Intermittent Androgen Deprivation Therapy
Not yet reported University of Arkansas 34 participants Est. completion 2028-10 1 site Stand-aloneOther conditions: Castration Sensitive Prostate CancerView official trial listing → -
Recruiting NCT NCT06090227
AMPK-activation by Metformin in FSGS: AMP-FSGS
Not yet reported, Not yet reported Yale University 30 participants Est. completion 2027-11 2 sites Stand-aloneOther conditions: Focal Segmental GlomerulosclerosisView official trial listing → -
Recruiting NCT NCT06096259
Preventing Injured Knees From osteoArthritis: Severity Outcomes
Not yet reported Brigham and Women's Hospital 512 participants Est. completion 2029-12 9 sitesOsteoarthritis Other conditions: ACL TearView official trial listing → -
Recruiting NCT NCT06120881
Precision Dosing of Metformin in Youth With T2D
Not yet reported University of California, San Francisco 20 participants Est. completion 2026-12-31 2 sites Stand-aloneType 2 diabetesView official trial listing → -
Recruiting NCT NCT06185179
Metformin and Muscle Recovery
Not yet reported University of Utah 50 participants Est. completion 2030-05-31 1 siteOther conditions: Muscle Atrophy or WeaknessView official trial listing → -
Recruiting NCT NCT06445946
DECIDE: A Comparative Effectiveness Trial of Metformin Versus Insulin for the Treatment of Gestational Diabetes
Not yet reported Ohio State University 1572 participants Est. completion 2030-12 24 sites Stand-aloneOther conditions: Gestational Diabetes Mellitus, Pregnancy, High RiskView official trial listing → -
Recruiting NCT NCT06459310
Pilot Study on Evaluating the Geroprotective Effect of Metformin
Not yet reported Xuanwu Hospital, Beijing 130 participants Est. completion 2028-07-31 1 site Stand-aloneOther conditions: Metformin, AgingView official trial listing → -
Recruiting NCT NCT06613854
Effect of Early Combination Antihyperglycemic Treatment on Metabolic Control in Individuals With Type 2 Diabetes
Not yet reported University Medical Centre Ljubljana 90 participants Est. completion 2027-12 1 siteType 2 diabetesView official trial listing → -
Recruiting NCT NCT06627322
A Registry-based Randomized Controlled Trial in Type 2 Diabetes With Cardiovascular Risk Factors (REMATCH)
Not yet reported Kyu Chang Won 5950 participants Est. completion 2029-09-30 2 sites Stand-aloneType 2 diabetesView official trial listing → -
Recruiting NCT NCT06707012
Efficacy of Metformin as an Adjunct to Standard Antidepressant Therapy in Treating Depression Among Obese Patients
Not yet reported Fazaia Ruth Pfau Medical College 140 participants Est. completion 2026-12 2 sites Stand-aloneOther conditions: DepressionView official trial listing → -
Recruiting NCT NCT06763328
Metformin for the Treatment of Insulin Resistance in Women With Stage I-III Breast Cancer Completing Chemotherapy
Not yet reported City of Hope Medical Center 80 participants Est. completion 2029-06-16 3 sitesOther conditions: Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage III Breast Cancer AJCC v8, Invasive Breast CarcinomaView official trial listing → -
Recruiting NCT NCT06806345
Hyperbaric Oxygen Therapy on Insulin Resistance in Postmenopause
Not yet reported, Not yet reported Cairo University 40 participants Est. completion 2025-04-28 1 site Stand-aloneOther conditions: Insulin Resistance SyndromeView official trial listing → -
Recruiting NCT NCT06875193
DM Treatment to Evaluate the Efficacy and Safety of Dapagliflozin or Pioglitazone in Patients with Type 2 Diabetes
Not yet reported Dong Wha Pharmaceutical Co. Ltd. 196 participants Est. completion 2025-12-31 1 siteOther conditions: Type2diabetesView official trial listing → -
Recruiting NCT NCT06924658
Metformin in Safety and Efficacy in Gouty Patients
Not yet reported Mostafa Bahaa 70 participants Est. completion 2026-11-20 1 siteOther conditions: GoutView official trial listing → -
Recruiting NCT NCT06948825
Effectiveness Study of a Lifestyle Intervention Versus Metformin in Mothers With Recent Gestational Diabetes
Not yet reported George Washington University 60 participants Est. completion 2026-11 1 siteOther conditions: Weight Loss, Gestational Diabetes Mellitus in Pregnancy, Postpartum CareView official trial listing → -
Recruiting NCT NCT07074379
Endotherapy and/or Extracorporeal Shockwave Lithotripsy for Painless Chronic Pancreatitis
Not yet reported Changhai Hospital 126 participants Est. completion 2027-08-01 1 siteOther conditions: Painless Chronic PancreatitisView official trial listing → -
Recruiting NCT NCT07093476
Efficacy and Safety of Add-On Therapy With Empagliflozin in Patients With Type 2 Diabetes on a Background of Alogliptin and Metformin
Not yet reported Celltrion 171 participants Est. completion 2027-04 1 siteType 2 diabetes Other conditions: Diabete Type 2, DMView official trial listing → -
Recruiting NCT NCT07129473
Hyperemesis Gravidarum Risk Reduction With Metformin
Not yet reported, Not yet reported University of Southern California 224 participants Est. completion 2031-03 2 sites Stand-aloneOther conditions: Hyperemesis GravidarumView official trial listing → -
Recruiting NCT NCT07131384
Interaction Between Inorganic Nitrate Supplementation and Metformin in Individuals With Prediabetes
Not yet reported University of Virginia 24 participants Est. completion 2027-06-30 1 sitePrediabetes Other conditions: Males, Females, Sedentary, MetforminView official trial listing → -
Recruiting NCT NCT07254572
Anti-atherosclerotic Efficacy of Selected Antidiabetic Drugs in Patients With Coronary Artery Disease and Pre-diabetes
Not yet reported National Institute of Cardiology, Warsaw, Poland 300 participants Est. completion 2029-08-01 1 siteCardiovascular diseasePrediabetesView official trial listing → -
Recruiting NCT NCT07289399
Is There a Benefit From Addition of Treadmill Walking to Diet Restriction in Psoriasis Women With PCOS?
Not yet reported Cairo University 40 participants Est. completion 2026-05-15 1 siteOther conditions: Psoriasis, Polycystic Ovary SyndromeView official trial listing → -
Recruiting NCT NCT07291297
Metformin Hydrochloride in Combination With Standard of Care Systemic Therapy in Previously Untreated Advanced Unresectable or Metastatic Soft Tissue Sarcoma
Not yet reported Wake Forest University Health Sciences 50 participants Est. completion 2033-10 2 sitesOther conditions: Sarcoma Metastatic, Sarcoma, Soft TissueView official trial listing → -
Recruiting NCT NCT07293325
Semaglutide and Tirzepatide for Genetic Aging Delay in Adults With Obesity
Not yet reported Second Affiliated Hospital, Zhejiang University, School of Medicine 66 participants Est. completion 2027-06-02 1 siteOther conditions: Adults With Simple ObesityView official trial listing → -
Recruiting NCT NCT07297290
Effect of Metformin Use on Weight Loss in Obese, Non-diabetic People (MOWRI)
Not yet reported University Of Nigeria Teaching Hospital 220 participants Est. completion 2027-09-30 2 sites Stand-aloneOther conditions: Obesity and Cardiovascular Risk, Insulin Resistance, Obesity (Body Mass Index >30 kg/m2)View official trial listing → -
Recruiting NCT NCT07366944
PCOS and Problem of Eye Dryness: Is There a Benefit From Lifetyle Changes
Not yet reported Cairo University 40 participants Est. completion 2026-06-05 1 siteOther conditions: Polycystic Ovary Syndrome, Dry Eye, ObesityView official trial listing → -
Recruiting NCT NCT07372625
A Study to Investigate the Effects of Multiple Doses of Rezatapopt on the Pharmacokinetics of Metformin, Rosuvastatin, Repaglinide, and Midazolam in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation.
Not yet reported PMV Pharmaceuticals, Inc 14 participants Est. completion 2028-01 5 sites Stand-aloneOther conditions: TP53 Y220C Mutation, Advanced Solid TumorsView official trial listing → -
Recruiting NCT NCT07379333
A Study to Evaluate Efficacy and Safety of HM11260C in Patients With Type 2 Diabetes Mellitus Inadequately Controlled With Metformin and Dapagliflozin
Not yet reported Hanmi Pharmaceutical Company Limited 118 participants Est. completion 2028-01 1 siteType 2 diabetesView official trial listing → -
Recruiting NCT NCT07442006
Glycemic Variability of Combination Therapies in T2DM
Not yet reported JW Pharmaceutical 178 participants Est. completion 2027-03-31 1 site Stand-aloneType 2 diabetesView official trial listing → -
Recruiting NCT NCT07446400
A Trial to Examine the Interaction of Repinatrabit With Ethinyl Estradiol/Norethindrone, Metformin,Carbamazepine, Rosuvastatin, and Methotrexate When Administered Together
Not yet reported Otsuka Pharmaceutical Development & Commercialization, Inc. 48 participants Est. completion 2026-11-07 1 siteOther conditions: Healthy VolunteersView official trial listing → -
Recruiting NCT NCT07550816
Drug-drug Interaction Study of ZT002 Injection in Overweight and Obese Participants
Not yet reported Beijing QL Biopharmaceutical Co.,Ltd 60 participants Est. completion 2027-03-26 1 site Stand-aloneOther conditions: Overweight,ObesityView official trial listing → -
Recruiting NCT NCT07591246
Efficay of Physical Activity Program in PCOS Females With Fatty Pancrease and Thyroid Hypofunction
Not yet reported Cairo University 40 participants Est. completion 2026-12-30 1 site Stand-aloneOther conditions: Polycystic Ovary Syndrome, Non-Alcoholic Fatty Pancreatic Disease, Subclinical hypothyroïdismView official trial listing → -
Recruiting NCT NCT07630779
Efficacy of Alpha Lipoic Acid Combined With Myo-Inositol in Non-Diabetic PCOS Patients
Not yet reported Beni-Suef University 180 participants Est. completion 2026-12 1 siteOther conditions: Poly Cystic Ovary SyndromeView official trial listing → -
Recruiting NCT NCT07693452
Metformin in Pseudomyxoma Peritonei Secondary to Appendiceal Mucinous Neoplasms
Not yet reported University of California, Irvine 15 participants Est. completion 2029-07 1 siteOther conditions: Appendiceal Mucinous Neoplasm, Pseudomyxoma PeritoneiView official trial listing → -
Recruiting NCT NCT07724132
An Evaluation of Treatments for Sustained Clinical Response (18 Months) in Symptomatic Alzheimer's Disease
Not yet reported University College, London 1200 participants Est. completion 2031-03 2 sitesOther conditions: Alzheimer's Disease (AD), Mild Cognitive Impairment Due to Alzheimer's Disease, Alzheimer Disease DementiaView official trial listing → -
Completed NCT NCT00005104
Randomized Study of Decreased Hyperinsulinemia on the Ovulatory Response to Clomiphene Citrate in Women With Polycystic Ovary Syndrome
Not yet reported National Center for Research Resources (NCRR) 99 participants 6 sitesOther conditions: Polycystic Ovary Syndrome, HyperinsulinismView official trial listing → -
Completed NCT NCT00018616
Improving Compliance With Metformin
Not yet reported US Department of Veterans Affairs 79 participants Est. completion 2005-01 1 siteOther conditions: DiabetesView official trial listing → -
Completed NCT NCT00032487
Glycemic Control and Complications in Diabetes Mellitus Type 2 (VADT)
Not yet reported VA Office of Research and Development 1791 participants Est. completion 2008-05-30 21 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT00035542
A Research Study to Determine the Safety and Efficacy of Glucovance Compared to Metformin and Glyburide in Children and Adolescents With Type 2 Diabetes.
Not yet reported Bristol-Myers Squibb Est. completion 2003-10 50 sitesOther conditions: Diabetes Mellitus, Non-Insulin-DependentView official trial listing → -
Completed NCT NCT00035568
A Research Study to Assess the Mechanism By Which Glucovance, Metformin, and Glyburide Work To Control Glucose Levels In Patients With Type 2 Diabetes
Not yet reported Bristol-Myers Squibb Est. completion 2003-06 9 sitesOther conditions: Diabetes Mellitus, Non-Insulin-DependentView official trial listing → -
Completed NCT NCT00067951
A Study To Evaluate The Safety And Efficacy Of An Investigational Diabetes Drug In Poorly Controlled Type II Diabetics
Not yet reported GlaxoSmithKline 190 participants Est. completion 2004-11-30 94 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT00081328
Treatment Options for Type 2 Diabetes in Adolescents and Youth (TODAY)
Not yet reported National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) 699 participants Est. completion 2014-02 16 sites Stand-aloneOther conditions: Diabetes Mellitus, Type IIView official trial listing → -
Completed NCT NCT00097500
Effects of Exenatide and Insulin Glargine in Subjects With Type 2 Diabetes
Not yet reported AstraZeneca 69 participants Est. completion 2009-12 3 sites Added to GLP-1Type 2 diabetesView official trial listing → -
Completed NCT NCT00097877
Comparison of Biphasic Insulin Aspart 70/30 Versus Insulin Glargine in Subjects With Type 2 Diabetes
Not yet reported Novo Nordisk A/S 293 participants Est. completion 2006-11 73 sitesType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT00099892
Efficacy and Safety of Vildagliptin in Combination With Metformin in Patients With Type 2 Diabetes
Not yet reported Novartis Pharmaceuticals 544 participants Est. completion 2005-09 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT00106704
Sulfonylurea Add-on Study in Patients With Type 2 Diabetes Mellitus (0431-035)
Not yet reported Merck Sharp & Dohme LLC 441 participants Est. completion 2007-01Type 2 diabetesView official trial listing → -
Completed NCT NCT00111631
A Study of DPP-IV Inhibitor in Patients With Type 2 Diabetes
Not yet reported Hoffmann-La Roche 218 participants Est. completion 2006-10 37 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00118963
Effect of Repaglinide Versus Metformin Treatment in Non-Obese Patients With Type-2-Diabetes
Not yet reported Steno Diabetes Center Copenhagen 102 participants Est. completion 2006-02 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT00121667
Study Assessing Saxagliptin Treatment In Type 2 Diabetic Subjects Who Are Not Controlled With Metformin Alone
Not yet reported AstraZeneca 1462 participants Est. completion 2010-02 152 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00121966
South Danish Diabetes Study: Evaluation of the Antidiabetic Treatment of Type 2 Diabetes Mellitus
Not yet reported Odense University Hospital 400 participants Est. completion 2007-07 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT00134303
Trial Comparing Metformin Versus Placebo in Non Alcoholic Steatohepatitis (NASH) Patients Receiving Bariatric Surgery for Obesity
Not yet reported University Hospital, Ghent 65 participants Est. completion 2006-03-31 1 site Stand-aloneOther conditions: ObesityView official trial listing → -
Completed NCT NCT00135330
An Evaluation of Exenatide and Rosiglitazone in Subjects With Type 2 Diabetes Mellitus
Not yet reported AstraZeneca 137 participants Est. completion 2008-07 19 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT00151411
Lifestyle Intervention and Metformin for Women With Polycystic Ovary Syndrome (PCOS)
Not yet reported Milton S. Hershey Medical Center 114 participants Est. completion 2008-03 1 siteOther conditions: Polycystic Ovary SyndromeView official trial listing → -
Completed NCT NCT00156897
Efficacy and Safety of ATL-962 in Obese Diabetics
Not yet reported Alizyme 600 participants Est. completion 2005-10 37 sitesOther conditions: Non-Insulin-Dependent Diabetes Mellitus, ObesityView official trial listing → -
Terminated NCT NCT00159211
Abdominal Adipose Tissue Distribution in Type 2 Diabetic Patients Treated During 6 Months With Pioglitazone or Insulin
Not yet reported Assistance Publique - Hôpitaux de Paris 28 participants Est. completion 2007-05 1 siteType 2 diabetesView official trial listing → -
Terminated NCT NCT00159575
Metformin in Assisted Reproduction-MET-AR-study
Not yet reported Norwegian University of Science and Technology 150 participants Est. completion 2010-04 2 sitesOther conditions: Polycystic Ovary SyndromeView official trial listing → -
Completed NCT NCT00184626
Comparison of Insulin Glargine Versus Biphasic Insulin Aspart 30/70 or Biphasic Insulin Aspart 30/70 in Combination With Metformin in Subjects With Type 2 Diabetes.
Not yet reported Novo Nordisk A/S 97 participants Est. completion 2005-10-24 1 siteType 2 diabetes Other conditions: DiabetesView official trial listing → -
Terminated NCT NCT00203632
Glitazones and Endothelial Function (GATE)
Not yet reported University of Calgary 40 participants Est. completion 2007-10 1 siteOther conditions: Diabetes MellitusView official trial listing → -
Completed NCT NCT00263276
A Trial of BMS-512148 in Patients With Type 2 Diabetes Mellitus
Not yet reported AstraZeneca 389 participants Est. completion 2007-02 144 sitesType 2 diabetesView official trial listing → -
Withdrawn NCT NCT00265746
Prevention of Diabetes Mellitus Development in Women Who Had Already Experienced A Gestational Diabetes
Not yet reported Medical University of LodzType 2 diabetesView official trial listing → -
Completed NCT NCT00269061
Study In Patients With Type 2 Diabetes Who Are Taking Metformin And Sulfonylurea, Metformin And Insulin, Or Insulin
Not yet reported GlaxoSmithKline 32 participants 1 siteOther conditions: Non-Insulin-Dependent Diabetes MellitusView official trial listing → -
Completed NCT NCT00272064
ELEONOR STUDY: Insulin Glulisine in Type 2 Diabetes Mellitus.
Not yet reported Sanofi 352 participants Est. completion 2008-05 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT00279045
Diabetes Study With Rosiglitazone Monotherapy Versus Metformin Or Glyburide/Glibenclamide
Not yet reported GlaxoSmithKline 4426 participants Est. completion 2006-06-19 490 sitesType 2 diabetesView official trial listing → -
Terminated NCT NCT00283049
Insulin Glargine Injection Treatment in Place of Thiazolidinedione (TZD), Sulfonylurea, or Metformin in Triple Agent Therapy for Type 2 Diabetes Mellitus (T2DM) Adult Subjects With Unsatisfactory Control
Not yet reported Sanofi 390 participants Est. completion 2008-11 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT00286442
Efficacy and Safety of Alogliptin Combined With Metformin in Participants With Type 2 Diabetes Mellitus
Not yet reported Takeda 527 participants Est. completion 2007-06 56 sites Stand-aloneOther conditions: Diabetes MellitusView official trial listing → -
Completed NCT NCT00290940
Evaluation of Glucose Lowering Effect, Safety and Tolerability of CS-917
Not yet reported Daiichi Sankyo 400 participants Est. completion 2007-04 66 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT00308373
Effects of Fats on Blood Glucose in People With and Without Type 2 Diabetes Mellitus
Not yet reported Mayo Clinic 73 participants Est. completion 2005-11 1 siteType 2 diabetesView official trial listing → -
Status unknown NCT NCT00317928
Efficacy of Metformin in PCOS: Metabolic and Hormonal Factors
Not yet reported Aarhus University Hospital Skejby 50 participants Est. completion 2004-09Other conditions: Polycystic Ovary SyndromeView official trial listing → -
Status unknown NCT NCT00319293
Efficacy of Metformin in Lean Women With Polycystic Ovary Syndrome
Not yet reported Aarhus University Hospital Skejby 20 participantsOther conditions: Polycystic Ovary SyndromeView official trial listing → -
Completed NCT NCT00324363
Safety and Efficacy of Exenatide in Patients With Type 2 Diabetes Using Metformin or Sulfonylureas and Metformin
Not yet reported AstraZeneca 466 participants Est. completion 2007-04 14 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT00327015
A Phase 3 Study of BMS-477118 in Combination With Metformin in Subjects With Type 2 Diabetes Who Are Not Controlled With Diet and Exercise
Not yet reported AstraZeneca 1306 participants Est. completion 2008-12 211 sitesOther conditions: DiabetesView official trial listing → -
Completed NCT NCT00328172
Efficacy and Safety of 3 Doses of BI1356 (Linagliptin) in Type 2 Diabetes Patients
Not yet reported Boehringer Ingelheim 302 participants 71 sitesType 2 diabetesView official trial listing → -
Terminated NCT NCT00332085
Pilot Trial of Chromium-Metformin Combination in Type 2 Diabetes
Not yet reported Bastyr University 40 participants Est. completion 2007-03 2 sitesType 2 diabetesView official trial listing → -
Terminated NCT NCT00348712
Efficacy and Safety of Inhaled Pre-prandial Human Insulin in Type 2 Diabetes
Not yet reported Novo Nordisk A/S 301 participants Est. completion 2008-03-05 74 sitesType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT00350779
Sitagliptin Metformin/PPARg Agonist Combination Therapy Add-on (0431-052)
Not yet reported Merck Sharp & Dohme LLC 262 participants Est. completion 2008-06-11Type 2 diabetesView official trial listing → -
Terminated NCT NCT00361868
Fenofibrate and Metformin Fixed Combination vs Rosiglitazone - FAME ROSI
Not yet reported Solvay Pharmaceuticals 88 participants Est. completion 2007-12 70 sites Stand-aloneOther conditions: Dyslipidemia, Glucose Metabolism DisorderView official trial listing → -
Completed NCT NCT00374907
A Study Assessing Saxagliptin Treatment in Subjects With Type 2 Diabetes Who Are Not Controlled With Diet and Exercise
Not yet reported AstraZeneca 156 participants Est. completion 2009-12 3 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00382096
Efficacy of Fixed Combination Therapy of Vildagliptin and Metformin Compared to the Individual Monotherapy Components in Drug Naive Patients With Type 2 Diabetes
Not yet reported Novartis Pharmaceuticals 1179 participants Est. completion 2008-06-03 2 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT00390273
Effect of Metformin on Lactate Metabolism
Not yet reported, Not yet reported Centre de Recherche en Nutrition Humaine Rhone-Alpe 20 participants Est. completion 2007-10 1 siteOther conditions: HyperlactatemiaView official trial listing → -
Completed NCT NCT00400231
The Fenofibrate and Metformin for Atherogenic Dyslipidemia (FAMA) Study
Not yet reported University of Pennsylvania 124 participants Est. completion 2008-03 1 siteMetabolic syndromeView official trial listing → -
Completed NCT NCT00402909
Safety and Efficacy of Nateglinide in Patients With Type 2 Diabetes Already Taking Insulin Glargine, Metformin and/or Pioglitazone or Rosiglitazone
Not yet reported Novartis Pharmaceuticals 28 participants Est. completion 2007-08 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT00420511
Beta-Cell Function and Sitagliptin Trial (BEST)
Not yet reported Samuel Lunenfeld Research Institute, Mount Sinai Hospital 21 participants Est. completion 2009-09 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT00423501
A Study of a GLP-1 Analogue in Patients With Type 2 Diabetes Treated With Metformin.
Not yet reported Hoffmann-La Roche 306 participants Est. completion 2007-11 49 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT00432276
Efficacy of Alogliptin and Pioglitazone in Subjects With Type 2 Diabetes Mellitus
Not yet reported Takeda 803 participants Est. completion 2009-06 86 sites Stand-aloneOther conditions: Diabetes MellitusView official trial listing → -
Terminated NCT NCT00441363
Efficacy and Safety of Cycloset® Compared With Placebo When Added to Metformin
Not yet reported VeroScience 66 participants Est. completion 2006-03Type 2 diabetesView official trial listing → -
Terminated NCT NCT00449605
A Glycemic Control Evaluation of Glimepiride Versus Rimonabant on Top of Metformin in Type 2 Diabetes
Not yet reported Sanofi 508 participants Est. completion 2009-03 15 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00449930
Sitagliptin Comparative Study in Patients With Type 2 Diabetes (0431-049)
Not yet reported Merck Sharp & Dohme LLC 1050 participants Est. completion 2008-07-25Type 2 diabetesView official trial listing → -
Completed NCT NCT00454233
A Safety and Efficacy Study With YM543 in Type 2 Diabetes Mellitus Subjects
Not yet reported Astellas Pharma Inc 97 participants Est. completion 2008-06 6 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT00463502
The Effect of Metformin Treatment on Thyroid Hormone Metabolism in Euthyroid Patients With Type 2 Diabetes Mellitus
Not yet reported Haydarpasa Numune State HospitalType 2 diabetesView official trial listing → -
Terminated NCT NCT00469586
Efficacy and Safety of Inhaled Insulin Compared to Metformin and Glimepiride in Type 2 Diabetes
Not yet reported Novo Nordisk A/S 174 participants Est. completion 2008-04-24 59 sitesType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT00473876
Metformin in Insulin Resistant Left Ventricular (LV) Dysfunction (TAYSIDE Trial)
Not yet reported University of Dundee 62 participants Est. completion 2009-04 1 siteHeart failure Other conditions: Insulin ResistanceView official trial listing → -
Terminated NCT NCT00479466
Dose-Range Finding Study for MK0893 (0893-008)
Not yet reported Merck Sharp & Dohme LLC 342 participants Est. completion 2008-05Type 2 diabetesView official trial listing → -
Withdrawn NCT NCT00481429
Predictive Markers of Glitazone Efficacy in Diabetic Patients - Pilot Study
Imperial College London Est. completion 2008-01 4 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT00486187
Effects of ROSIglitazone on Inflammatory Markers and Adipokines in Diabetic Patients Using an Angiotensin Receptor Blocker (TELmisartan) - The ROSITEL Study
Not yet reported Dr. Milan Gupta 103 participants Est. completion 2009-06 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT00490178
Acceptability Study of a New Fixed Combination of Fenofibrate 80 mg BID and Metformin 1000 mg BID in Type 2 Diabetes and Dyslipidemia
Not yet reported Solvay Pharmaceuticals 29 participants 3 sitesType 2 diabetes Other conditions: DyslipidemiaView official trial listing → -
Terminated NCT NCT00494663
A Phase 2b Study of DIO-902 or DIO-902 Placebo in Addition to Metformin and Atorvastatin or Atorvastatin Placebo for Type 2 Diabetes
Not yet reported DiObex 200 participants Est. completion 2008-12 24 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT00494884
Vildagliptin 100 mg Once Daily vs. Placebo as add-on Therapy in Patients With Type 2 Diabetes Inadequately Controlled With Metformin
Not yet reported Novartis Est. completion 2008-07 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT00510588
Chronic Inflammatory Activation in Fat Tissue: an Atherogenic Factor in Stable Coronary Artery Disease
Not yet reported University of Leipzig 120 participants Est. completion 2013-10 1 siteCardiovascular diseasePrediabetes Other conditions: ObesityView official trial listing → -
Completed NCT NCT00513630
Study on the Prognosis and Effect of Anti-diabetic Drugs on Type-2 Diabetes Mellitus With Coronary Artery Disease
Not yet reported Shanghai Jiao Tong University School of Medicine 304 participants Est. completion 2010-07 1 siteType 2 diabetesCardiovascular diseaseView official trial listing → -
Completed NCT NCT00528879
A Phase III Study of BMS-512148 (Dapagliflozin) in Patients With Type 2 Diabetes Who Are Not Well Controlled on Metformin Alone
Not yet reported AstraZeneca 915 participants Est. completion 2010-05 75 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00538486
A Randomized, Double-Blind, Active Control Trial Comparing Effects of Telmisartan, Candesartan and Amlodipine, Alone or Plus Metformin, on Non-Diabetic, Obese Hypertensive Patients
Not yet reported Third Military Medical University 360 participants Est. completion 2009-06 1 site Stand-aloneOther conditions: Hypertension, ObesityView official trial listing → -
Withdrawn NCT NCT00541567
BMS-646256 in Obese and Overweight Type 2 Diabetics
Not yet reported, Not yet reported Solvay Pharmaceuticals 600 participants Est. completion 2010-06Type 2 diabetesView official trial listing → -
Completed NCT NCT00541775
Safety/Efficacy of Sitagliptin in Patient w/ Type 2 Diabetes (0431-801)
Not yet reported Merck Sharp & Dohme LLC 273 participants Est. completion 2007-03 Stand-aloneType 2 diabetesView official trial listing → -
Terminated NCT NCT00543738
MK0767 and Metformin Combination Study (0767-028)
Not yet reported Merck Sharp & Dohme LLC 114 participants Est. completion 2003-12Other conditions: Diabetes MellitusView official trial listing → -
Status unknown NCT NCT00544518
Impact of Benfluorex Versus Metformin on Glucose Control and Insulin Secretion in Chinese Type 2 Diabetic Patients
Not yet reported Air Force Military Medical University, China 240 participants Est. completion 2008-10 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT00545584
Addition Of Januvia (Sitagliptin) Improves Glycemic Control In Patients Inadequately Controlled By Metformin (MK0431-078)
Not yet reported Merck Sharp & Dohme LLC 1512 participants Est. completion 2009-11-19Other conditions: Diabetes Mellitus, Non-Insulin-DependentView official trial listing → -
Completed NCT NCT00546442
Treatment Insulin Resistence in HCV G-1 Patient
Not yet reported Valme University Hospital 126 participants Est. completion 2007-01 19 sitesOther conditions: Chronic Hepatitis CView official trial listing → -
Completed NCT NCT00546728
The Vascular Effects of Exenatide Versus Metformin in Patients With Pre-Diabetes
Not yet reported St. Paul Heart Clinic 50 participants Est. completion 2011-07 2 sitesPrediabetesView official trial listing → -
Completed NCT NCT00575588
52-week add-on to Metformin Comparison of Saxagliptin and Sulphonylurea, With a 52-week Extension Period
Not yet reported AstraZeneca 891 participants Est. completion 2010-08 94 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00592969
Efficacy and Safety of Metformin Plus Biphasic Insulin Aspart 30 in Type 2 Diabetes
Not yet reported Novo Nordisk A/S 164 participants Est. completion 2004-11-02 2 sitesType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT00598793
Biphasic Insulin Aspart 30 in Type 2 Diabetes Failing OAD Therapy
Not yet reported Novo Nordisk A/S 242 participants Est. completion 2004-03 27 sitesType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT00601250
Efficacy and Safety of B I1356 (Linagliptin) vs. Placebo Added to Metformin Background Therapy in Patients With Type 2 Diabetes
Not yet reported Boehringer Ingelheim 701 participants 82 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT00603239
Safety and Efficacy of Exenatide in Patients With Type 2 Diabetes Using a Thiazolidinedione or a Thiazolidinedione and Metformin
Not yet reported AstraZeneca 165 participants Est. completion 2009-07 25 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT00605475
Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ACZ885 in Patients With Type 2 Diabetes
Not yet reported Novartis 231 participants Est. completion 2010-09 13 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT00613951
Comparison of Two NN5401 Formulations Versus Biphasic Insulin Aspart 30, All in Combination With Metformin in Subjects With Type 2 Diabetes
Not yet reported Novo Nordisk A/S 182 participants Est. completion 2008-08 31 sitesType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT00627445
Effect of Biphasic Insulin Aspart 50 on Blood Glucose Control in Subjects With Type 2 Diabetes
Not yet reported Novo Nordisk A/S 441 participants Est. completion 2009-01 1 siteType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT00636766
Diagnosis and Therapy of Vulnerable Atherosclerotic Plaque
Not yet reported Aristotle University Of Thessaloniki 300 participants Est. completion 2009-01 1 site Stand-aloneCardiovascular diseaseType 2 diabetesMetabolic syndrome Other conditions: Carotid AtherosclerosisView official trial listing → -
Completed NCT NCT00637273
A Study to Compare the Glycemic Effects, Safety, and Tolerability of Exenatide Once Weekly to Those of Sitagliptin and Pioglitazone,in Subjects With Type 2 Diabetes Treated With Metformin (DURATION - 2)
Not yet reported AstraZeneca 514 participants Est. completion 2009-07 62 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT00638716
A Study to Evaluate the Efficacy and Safety of CJC-1134-PC in Patients With Type 2 Diabetes Mellitus Who Are Currently on Metformin Monotherapy
Not yet reported ConjuChem 122 participants Est. completion 2008-11 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT00643851
An Efficacy & Safety Study of BMS-512148 in Combination With Metformin Extended Release Tablets
Not yet reported AstraZeneca 994 participants Est. completion 2009-08 99 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00648492
Food Study Metformin Hydrochloride ER Tablets 500 mg and Glucophage® XR 500 mg
Not yet reported Mylan Pharmaceuticals Inc 18 participants Est. completion 2002-11 1 siteOther conditions: HealthyView official trial listing → -
Completed NCT NCT00649350
Food Study Metformin Hydrochloride ER Tablets 750 mg and Glucophage XR 750 mg
Not yet reported Mylan Pharmaceuticals Inc 28 participants Est. completion 2003-12 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT00657943
The Copenhagen Insulin and Metformin Therapy Trial
Not yet reported Steno Diabetes Center Copenhagen 415 participants Est. completion 2012-12 9 sitesType 2 diabetes Other conditions: Atherosclerosis, ArteriosclerosisView official trial listing → -
Completed NCT NCT00660907
Efficacy and Safety of Dapagliflozin in Combination With Metformin in Type 2 Diabetes Patients
Not yet reported AstraZeneca 1217 participants Est. completion 2013-01 76 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT00661362
Evaluate Efficacy and Safety of Saxagliptin in Combination With Metformin in Adult Patients With Type 2 Diabetes
Not yet reported AstraZeneca 570 participants Est. completion 2009-09 30 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00669864
Effect of Biphasic Insulin Aspart 30 Combined With Metformin on Blood Glucose Control in Subjects With Type 2 Diabetes Inadequately Controlled With Basal Insulin
Not yet reported Novo Nordisk A/S 293 participants Est. completion 2009-04 1 siteType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT00676338
Safety and Efficacy of Exenatide Once Weekly Injection Versus Metformin, Dipeptidyl Peptidase-4 Inhibitor, or Thiazolidinedione as Monotherapy in Drug-Naive Patients With Type 2 Diabetes (DURATION-4)
Not yet reported AstraZeneca 820 participants Est. completion 2011-01 106 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT00678080
Metformin Versus Insulin in Pregnant Women With Type 2 Diabetes
Not yet reported The University of Texas Health Science Center, Houston 25 participants Est. completion 2011-08 3 sites Stand-aloneOther conditions: Pregnancy ComplicationsView official trial listing → -
Completed NCT NCT00682448
Metformin for the Prevention of the Metabolic Side-effects of Zyprexa
Not yet reported Rush University Medical Center 25 participants Est. completion 2011-08 1 siteOther conditions: Metabolic ComplicationsView official trial listing → -
Completed NCT NCT00686634
Sitagliptin in Combination With Metformin and Sulfonylurea
Not yet reported Charles Drew University of Medicine and Science 108 participants Est. completion 2010-03 1 siteType 2 diabetesView official trial listing → -
Terminated NCT NCT00690456
Effect of Rimonabant and Metformin Combination on Glycemic Control in Patients With Type 2 Diabetes
Not yet reported Sanofi 403 participants Est. completion 2009-02 13 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00694057
Safety, Tolerance and Activity of HE3286 in Patients With Type 2 Diabetes Mellitus
Not yet reported Harbor Therapeutics 164 participants Est. completion 2010-01 22 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT00694759
Cortisol Regulation in Polycystic Ovary Syndrome (PCOS)
Not yet reported Oregon Health and Science University 37 participants Est. completion 2011-07 1 siteOther conditions: Polycystic Ovary SyndromeView official trial listing → -
Status unknown NCT NCT00699036
Rosiglitazone Versus Rosiglitazone and Metformin Versus Rosiglitazone and Avandia in the Treatment of Nonalcoholic Steatohepatitis (NASH)
Not yet reported Brooke Army Medical Center 165 participants Est. completion 2009-08 1 siteMASHMASLDView official trial listing → -
Completed NCT NCT00700817
The Effect of Liraglutide Compared to Sitagliptin, Both in Combination With Metformin on Glycaemic Control in Subjects With Type 2 Diabetes Mellitus
Not yet reported Novo Nordisk A/S 665 participants Est. completion 2010-06 166 sites Added to GLP-1Type 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT00703755
A Randomized, Double-Blind Trial Comparing the Efficacy and Safety of Fenofibrate, Metformin, Their Combination and Placebo in Patients With Metabolic Syndrome.
Not yet reported Solvay Pharmaceuticals 2288 participants Est. completion 2004-06 101 sitesMetabolic syndromeView official trial listing → -
Completed NCT NCT00714233
Treatment of Adolescent Polycystic Ovary Syndrome (PCOS)
Not yet reported University of Rochester 43 participants Est. completion 2007-12 Stand-aloneOther conditions: Polycystic Ovary SyndromeView official trial listing → -
Completed NCT NCT00722371
MK0431 and Pioglitazone Co-Administration Factorial Study in Patients With Type 2 Diabetes Mellitus (0431-102 AM2)
Not yet reported Merck Sharp & Dohme LLC 1615 participants Est. completion 2011-03-25 Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00723307
Carotid Atherosclerosis: MEtformin for Insulin ResistAnce Study
Not yet reported Professor Naveed Sattar 173 participants Est. completion 2012-12 1 siteCardiovascular diseaseView official trial listing → -
Completed NCT NCT00727857
Efficacy and Safety of Pioglitazone and Metformin Combination Therapy in Treating Type 2 Diabetes Mellitus.
Not yet reported Takeda 600 participants Est. completion 2008-08 77 sites Stand-aloneOther conditions: Diabetes MellitusView official trial listing → -
Completed NCT NCT00740051
A Randomised, db, Placebo-controlled Study of BI 1356 for 18 Weeks Followed by a 34 Week Double-blind Extension Period (Placebo Patients Switched to Glimepiride) in Type 2 Diabetic Patients for Whom Treatment With Metformin is Inappropriate
Not yet reported Boehringer Ingelheim 227 participants 53 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT00744367
A Study of Taspoglutide Versus Placebo for the Treatment of Patients With Type 2 Diabetes Mellitus Inadequately Controlled With Metformin Plus Pioglitazone.
Not yet reported Hoffmann-La Roche 326 participants Est. completion 2010-11 113 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT00749190
BI 10773 add-on to Metformin in Patients With Type 2 Diabetes
Not yet reported Boehringer Ingelheim 495 participants 116 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT00751114
Evaluation of Insulin Glargine Versus Sitagliptin in Insulin-naive Patients
Not yet reported Sanofi 515 participants Est. completion 2011-07 17 sitesType 2 diabetesView official trial listing → -
Terminated NCT NCT00762957
Safety and Efficacy of TAK-559 in Combination With Metformin in Patients With Type 2 Diabetes Mellitus.
Not yet reported Takeda 15 participants Est. completion 2004-12 Stand-aloneOther conditions: Diabetes MellitusView official trial listing → -
Completed NCT NCT00763815
GLP-1 Receptor Agonist Lixisenatide in Patients With Type 2 Diabetes for Glycemic Control and Safety Evaluation, on Top of Pioglitazone
Not yet reported Sanofi 484 participants Est. completion 2011-06 150 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT00767351
Variation in Serum Levels of Metformin in Patients With Reduced Renal Function
Skane University Hospital 30 participants Est. completion 2009-07Type 2 diabetes Other conditions: Metformin, PharmacokineticsView official trial listing → -
Completed NCT NCT00770445
Efficacy of Pioglitazone and Metformin on Cardiovascular Risk in Subjects With Insulin-Treated Type 2 Diabetes Mellitus.
Not yet reported Takeda 121 participants Est. completion 2010-07 18 sites Stand-aloneOther conditions: Diabetes MellitusView official trial listing → -
Completed NCT NCT00770835
Efficacy and Safety of Pioglitazone in Treating Subjects With Vascular Complications Associated With Type 2 Diabetes Mellitus.
Not yet reported Takeda 39 participants Est. completion 2011-05 2 sitesOther conditions: Diabetes MellitusView official trial listing → -
Completed NCT NCT00772174
Efficacy and Safety Study of Pioglitazone Combined With Metformin on Metabolic Syndrome in Subjects With Type 2 Diabetes
Not yet reported Takeda 418 participants Est. completion 2008-02 Stand-aloneOther conditions: Diabetes MellitusView official trial listing → -
Completed NCT NCT00778141
Bioequivalence Study of Metformin HCl 750 mg XR Tablets Under Non Fasting Conditions
Not yet reported Ranbaxy Laboratories Limited 36 participants Est. completion 2004-06 1 siteOther conditions: HealthyView official trial listing → -
Completed NCT NCT00783744
Insulin Glargine Combination Therapies in Type II Diabetics
Not yet reported Sanofi 375 participants 10 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT00789035
12 Weeks Treatment With 3 Different Doses of BI 10773 in Type 2 Diabetic Patients
Not yet reported Boehringer Ingelheim 408 participants 74 sitesType 2 diabetesView official trial listing → -
Status unknown NCT NCT00790348
Effect of Januvia on Ghrelin and Other Gut Hormones in Patients With Diabetes
Wayne State University 45 participants 1 siteType 2 diabetesView official trial listing → -
Terminated NCT NCT00794963
Aggressive Treatment of Metabolic Syndrome in Patients Receiving Clozapine for Schizophrenia
Not yet reported Northwell Health 8 participants Est. completion 2010-05 1 site Stand-aloneMetabolic syndromeView official trial listing → -
Completed NCT NCT00806234
Reducing Weight Gain and Improving Metabolic Function in Children Being Treated With Antipsychotics
Not yet reported Johns Hopkins University 127 participants Est. completion 2014-03 4 sitesOther conditions: Psychotic DisordersView official trial listing → -
Completed NCT NCT00819884
To Evaluate 24-hr Glucose After OD vs BD AZD1656
Not yet reported AstraZeneca 36 participants Est. completion 2009-05 1 siteOther conditions: Type II DiabetesView official trial listing → -
Completed NCT NCT00822211
Efficacy of add-on Therapy With Vildagliptin in Chinese Patients With Type 2 Diabetes Inadequately Controlled With Prior Metformin Monotherapy
Not yet reported Novartis 404 participants Est. completion 2009-12 17 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT00823992
A Study of Taspoglutide Versus Placebo for the Treatment of Obese Patients With Type 2 Diabetes Mellitus Inadequately Controlled With Metformin Monotherapy
Not yet reported Hoffmann-La Roche 305 participants Est. completion 2010-05 71 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT00830076
A Study of the Effects of Co-Administration of Sitagliptin (MK-0431) and Metformin on Incretin Hormone Concentrations (MK-0431-110)
Not yet reported Merck Sharp & Dohme LLC 18 participants Est. completion 2009-05-14Type 2 diabetesView official trial listing → -
Completed NCT NCT00833027
ALPHA Sitagliptin Add on to Metformin (0431-103)
Not yet reported Merck Sharp & Dohme LLC 608 participants Est. completion 2009-10-30Other conditions: Diabetes MellitusView official trial listing → -
Completed NCT NCT00834743
Metformin ER 750 mg Tablets, Fasting
Not yet reported Teva Pharmaceuticals USA 32 participants Est. completion 2003-08 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT00835497
5 mg Glipizide/500 mg Metformin Hydrochloride Tablets, Fasting
Not yet reported Teva Pharmaceuticals USA 40 participants Est. completion 2004-06 2 sitesOther conditions: HealthyView official trial listing → -
Completed NCT NCT00835861
Effectiveness of Metformin Compared to Insulin in Pregnant Women With Mild Preexisting or Early Gestational Diabetes
Not yet reported University of North Carolina, Chapel Hill 31 participants Est. completion 2010-04 1 site Stand-aloneOther conditions: Non Insulin Dependent Diabetes, PregnancyView official trial listing → -
Completed NCT NCT00836472
Glyburide/Metformin 5 mg/500 mg Film-Coated Tablets, Fasting
Not yet reported Teva Pharmaceuticals USA 60 participants Est. completion 2003-04 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT00838903
Efficacy and Safety of Albiglutide in Treatment of Type 2 Diabetes
Not yet reported GlaxoSmithKline 1049 participants Est. completion 2013-04 386 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT00839527
A Study to Determine the Safety and Efficacy of Albiglutide in Subjects With Type 2 Diabetes
Not yet reported GlaxoSmithKline 685 participants Est. completion 2013-04 358 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT00849056
Safety and Efficacy of Albiglutide in Type 2 Diabetes
Not yet reported GlaxoSmithKline 310 participants Est. completion 2013-01 331 sites Added to GLP-1Type 2 diabetesView official trial listing → -
Completed NCT NCT00856986
The Effect of Insulin Detemir in Combination With Liraglutide and Metformin Compared to Liraglutide and Metformin in Subjects With Type 2 Diabetes
Not yet reported Novo Nordisk A/S 987 participants Est. completion 2010-11 233 sites Added to GLP-1Type 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT00859898
Study of Dapagliflozin in Combination With Metformin XR to Initiate the Treatment of Type 2 Diabetes
Not yet reported AstraZeneca 1093 participants Est. completion 2010-05 123 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00865241
A Relative Bioavailability Study of Glyburide/Metformin HCl 5 mg/500 mg Tablets Under Fasting Conditions
Not yet reported Actavis Inc. 36 participants Est. completion 2002-11 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT00865748
A Relative Bioavailability Study of Metformin HCl 500 mg ER Tablets Under Fasting Conditions
Not yet reported Actavis Inc. 40 participants Est. completion 2004-01 1 siteOther conditions: HealthyView official trial listing → -
Terminated NCT NCT00881725
A Study of Pre-operative Metformin in Prostate Cancer
Not yet reported University Health Network, Toronto 24 participants Est. completion 2012-06 1 siteOther conditions: Prostate CancerView official trial listing → -
Status unknown NCT NCT00883259
Metformin and Gestational Diabetes in High-risk Patients: a RCTs
Not yet reported University Magna Graecia 80 participants 3 sites Stand-aloneOther conditions: Obesity, Polycystic Ovary Syndrome, Gestational DiabetesView official trial listing → -
Terminated NCT NCT00883766
Polycystic Ovary Syndrome (PCOS) and In Vitro Fertilization (IVF): A Comparison Between Standard Long Protocol Versus an Antagonist Protocol Starting on Day 1
Not yet reported Fundacion Dexeus 172 participants Est. completion 2012-06 1 site Stand-aloneOther conditions: Polycystic Ovary Syndrome, In Vitro FertilizationView official trial listing → -
Completed NCT NCT00897884
Clinical and Biologic Effects of Metformin in Early Stage Breast Cancer
Not yet reported Mount Sinai Hospital, Canada 39 participants Est. completion 2011-07 2 sitesOther conditions: Breast CancerView official trial listing → -
Completed NCT NCT00911313
Letrozole or Combined Metformin Clomiphene Citrate (CC) for Women With CC Resistant Polycystic Ovary Syndrome
Not yet reported Mansoura University 250 participants Est. completion 2009-01 1 siteOther conditions: Polycystic Ovary SyndromeView official trial listing → -
Completed NCT NCT00924573
Comparative Study of HOE490 O (Glimepiride and Metformin) Compared With Placebo on Top of Glimepiride
Not yet reported Sanofi 189 participants Est. completion 2010-03 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00929539
Safety and Efficacy Study of JTT-130 in Obese Type 2 Diabetic Patients
Not yet reported Akros Pharma Inc. 496 participants Est. completion 2010-07 62 sitesOther conditions: Type II Diabetes MellitusView official trial listing → -
Status unknown NCT NCT00935805
Glycemic And Blood Pressure Control In Type 2 Diabetes, In A Primary Care Unit: A Staged Management Strategy
Hospital de Clinicas de Porto Alegre 124 participants Est. completion 2012-07 1 siteOther conditions: Diabetes Mellitus, Arterial HypertensionView official trial listing → -
Completed NCT NCT00940472
Study on DMMET-01 Versus Metformin on Improvement of Metabolic Control in Naive Type 2 Diabetes Patients
Not yet reported, Not yet reported Laboratorios Silanes S.A. de C.V. 20 participants 1 siteOther conditions: Diabetes Type 2View official trial listing → -
Completed NCT NCT00941148
Beta-Cell Function of Insulin Glargine Compared to Neutral Protamine Hagedorn (NPH) Insuline and to Insulin Detemir in Combination With Metformin
Not yet reported ikfe-CRO GmbH 30 participants Est. completion 2009-03 1 siteOther conditions: Type 2 Diabetic Patients, Insufficient Metabolic Control, OAD TreatmentView official trial listing → -
Completed NCT NCT00941239
Tolerability and Pharmacokinetics of Metformin and Metformin Extended Release (ER)
Not yet reported Laboratorios Silanes S.A. de C.V. 24 participants Est. completion 2007-02 1 siteOther conditions: HealthyView official trial listing → -
Status unknown NCT NCT00941382
Sibutramine-metformin Combination Versus Sibutramine and Metformin Monotherapy in Obese Patients
Not yet reported Laboratorios Silanes S.A. de C.V. 60 participants Est. completion 2009-09 1 site Stand-aloneOther conditions: ObesityView official trial listing → -
Completed NCT NCT00942123
Study On the Role of Mitochondrial Dysfunction in the Pathogenesis of Metformin-associated Lactic Acidosis
Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico 10 participants Est. completion 2011-10 1 siteOther conditions: Lactic Acidosis, MetforminView official trial listing → -
Completed NCT NCT00942188
A Study of LY2189102 in Patients With Type 2 Diabetes
Not yet reported Eli Lilly and Company 106 participants Est. completion 2010-11 18 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT00960661
A Trial Comparing Two Therapies: Basal Insulin/Glargine, Exenatide and Metformin Therapy (BET) or Basal Insulin/Glargine, Bolus Insulin Lispro and Metformin Therapy (BBT) in Subjects With Type 2 Diabetes
Not yet reported AstraZeneca 1036 participants Est. completion 2012-08 95 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT00965991
Metformin Compared to Glyburide in Gestational Diabetes
Not yet reported University of New Mexico 149 participants Est. completion 2023-08 1 siteOther conditions: Gestational DiabetesView official trial listing → -
Completed NCT NCT00969566
Predictive Parameters for Efficacy of Sitagliptin and Metformin Combination
Not yet reported Seoul National University Bundang Hospital 150 participants Est. completion 2011-07 1 siteOther conditions: DiabetesView official trial listing → -
Completed NCT NCT00970593
Study Evaluating Safety, Tolerability, And Action Of OAP-189 In Subjects With Type 2 Diabetes On Metformin
Not yet reported Pfizer 92 participants Est. completion 2011-07-25 2 sitesOther conditions: Diabetes MellitusView official trial listing → -
Completed NCT NCT00978263
Comparison of Glargine and Oral Antidiabetic Drugs (OADs) in Newly Diagnosed Type 2 Diabetes
Not yet reported Chongqing Medical University 47 participants Est. completion 2012-06 1 site Stand-aloneOther conditions: DiabetesView official trial listing → -
Terminated NCT NCT00984490
Metformin Hydrochloride in Treating Women With Stage I or Stage II Breast Cancer That Can Be Removed By Surgery
Not yet reported Vanderbilt-Ingram Cancer Center 5 participants Est. completion 2011-07 3 sites Stand-aloneOther conditions: Breast CancerView official trial listing → -
Completed NCT NCT00986401
Safety and Tolerability of Trospium Chloride and Metformin Hydrochloride in Healthy Subjects
Not yet reported Allergan 44 participants Est. completion 2009-11 1 siteOther conditions: HealthyView official trial listing → -
Status unknown NCT NCT00988078
Effects of Metformin and Oral Hormonal Contraceptive in Adolescents With Polycystic Ovary Syndrome
Not yet reported Federal University of São Paulo 90 participants Est. completion 2013-12 1 siteOther conditions: Polycystic Ovary SyndromeView official trial listing → -
Status unknown NCT NCT00991055
Comparison of the Efficacy and Safety Between Pioglitazone and Placebo Added to Combination Therapy in Type 2 Diabetes
Not yet reported National Cheng-Kung University Hospital 40 participants Est. completion 2010-10 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT00993187
Efficacy and Safety of Sitagliptin/Metformin Fixed-Dose Combination (FDC) Compared to Glimepiride in Participants With Type 2 Diabetes Mellitus (MK-0431A-202)
Not yet reported Merck Sharp & Dohme LLC 292 participants Est. completion 2013-10-29Type 2 diabetesView official trial listing → -
Completed NCT NCT00996658
Linagliptin Versus Placebo in Type 2 Diabetic Patients With Inadequate Glycaemic Control on Metformin in Combination With Pioglitazone
Not yet reported Boehringer Ingelheim 278 participants 52 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT01002807
Bioavailability Study of Fixed Dose Combination (FDC) Formulations of Dapagliflozin and Metformin XR Versus Individual Component Coadministered to Healthy Subjects in a Fasted State
Not yet reported AstraZeneca 15 participants Est. completion 2010-01 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT01005160
Drug Interaction Between CKD-501 and Metformin
Not yet reported Chong Kun Dang Pharmaceutical 24 participants Est. completion 2010-02Other conditions: Healthy Male VolunteersView official trial listing → -
Completed NCT NCT01021579
Effects of Metformin Plus Simvastatin on Polycystic Ovarian Syndrome (PCOS): A Prospective, Randomized, Double-Blind, Placebo-Controlled Study
Not yet reported Fasa University of Medical Sciences 84 participants Est. completion 2009-11 1 siteOther conditions: Polycystic Ovary SyndromeView official trial listing → -
Completed NCT NCT01022658
INSUlin Regimens and VASCular Functions
Not yet reported Assistance Publique - Hôpitaux de Paris 42 participants Est. completion 2011-07 1 siteType 2 diabetesView official trial listing → -
Terminated NCT NCT01024244
A Study of LY2599506 in Patients With Type 2 Diabetes
Not yet reported Eli Lilly and Company 78 participants Est. completion 2010-07 16 sitesType 2 diabetesView official trial listing → -
Status unknown NCT NCT01025765
The Effects of Oral Hypoglycemic Agents on Chronic Hepatitis C Patients Receiving Peg-Intron Plus Ribavirin
Not yet reported National Taiwan University Hospital 80 participants Est. completion 2012-12 1 siteOther conditions: Chronic Hepatitis CView official trial listing → -
Completed NCT NCT01033773
Stop Emergency Room Visits for Hyperglycemia Project - District of Columbia (DC)
Not yet reported Medstar Health Research Institute 86 participants Est. completion 2009-01 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT01037660
Effects of Lipemia and Metformin on Endothelial Function
Not yet reported Boston University 139 participants Est. completion 2016-12-01 1 site Stand-aloneCardiovascular diseaseView official trial listing → -
Completed NCT NCT01043965
Myocardial Perfusion in Type 2 Diabetes
Not yet reported, Not yet reported University of Sao Paulo General Hospital 61 participants Est. completion 2009-08Type 2 diabetesView official trial listing → -
Completed NCT NCT01045707
Comparison of NN5401 Versus Insulin Glargine, Both Combined With Metformin Treatment, in Subjects With Type 2 Diabetes
Not yet reported Novo Nordisk A/S 530 participants Est. completion 2010-10 92 sitesType 2 diabetes Other conditions: DiabetesView official trial listing → -
Status unknown NCT NCT01046500
Myo-inositol Versus Metformin Administration in Post-menopausal Women With Metabolic Syndrome
Not yet reported University of Messina 100 participants Est. completion 2014-12 1 siteMetabolic syndromeView official trial listing → -
Completed NCT NCT01064687
A Study in Participants With Type 2 Diabetes Mellitus
Not yet reported Eli Lilly and Company 978 participants Est. completion 2012-05 89 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT01065298
Efficacy Of Autologous Bone Marrow Derived Stem Cell Transplantation In Patients With Type 2 Diabetes Mellitus-2
Post Graduate Institute of Medical Education and Research, Chandigarh 30 participants Est. completion 2011-07 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT01075282
A Study in Participants With Type 2 Diabetes Mellitus (AWARD-2)
Not yet reported Eli Lilly and Company 810 participants Est. completion 2012-11 78 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01077323
A Retrospective Cohort Study of Acute Pancreatitis in Relation to Use of Exenatide and Other Antidiabetic Agents
AstraZeneca 363766 participants Est. completion 2008-03 1 siteType 2 diabetes Other conditions: Healthy Subjects (Treated With no Diabetes Therapies)View official trial listing → -
Terminated NCT NCT01089790
Safety and Efficacy of Dutogliptin in Patients With Type 2 Diabetes Mellitus Receiving Background Treatment With Glimepiride Alone or in Combination With Metformin or With Pioglitazone Alone
Not yet reported Forest Laboratories 141 participants 149 sitesType 2 diabetesView official trial listing → -
Status unknown NCT NCT01101204
The Effects of Hypolipemic and Antidiabetic Treatment on Cytokines
Not yet reported Medical University of Silesia 200 participants Est. completion 2012-12 1 siteOther conditions: Diabetes, Dyslipidemia, Inflammation, CytokinesView official trial listing → -
Completed NCT NCT01106651
A Safety and Efficacy Study of Canagliflozin in Older Patients (55 to 80 Years of Age) With Type 2 Diabetes Mellitus
Not yet reported Janssen Research & Development, LLC 716 participants Est. completion 2013-05 86 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01107717
Durability of Combination Therapy With Exenatide/Pioglitazone/Metformin vs. Conventional Therapy in New Onset T2DM
Not yet reported The University of Texas Health Science Center at San Antonio 318 participants Est. completion 2023-02-03 1 site Stand-aloneOther conditions: DiabetesView official trial listing → -
Withdrawn NCT NCT01107808
Calcium, Vitamin D and Metformin to Treat Insulin Resistance in Obese African American Adolescent Females
Not yet reported University of Alabama at Birmingham Est. completion 2011-03Other conditions: Insulin Resistance, Insulin Sensitivity, Obesity, Vitamin D DeficiencyView official trial listing → -
Completed NCT NCT01115140
Metformin and Folate in Pregnant Polycystic Ovary Syndrome(PCOS) Women
Not yet reported University Magna Graecia 50 participants Est. completion 2011-05 1 site Stand-aloneOther conditions: Pregnancy, Polycystic Ovary SyndromeView official trial listing → -
Completed NCT NCT01119846
A Study in Type 2 Diabetics of Single and Multiple Doses of Orally Administered GSK1292263 to Investigate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics
Not yet reported GlaxoSmithKline 100 participants Est. completion 2010-03-19 7 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT01123980
Comparison of the Blood Sugar Lowering Effect of Biphasic Insulin Aspart 30 and Insulin Glargine Both Combined With Metformin and Glimepiride in Chinese and Japanese Subjects With Type 2 Diabetes New to Insulin Treatment
Not yet reported Novo Nordisk A/S 521 participants Est. completion 2011-06 34 sites Stand-aloneType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT01125150
Spectroscopic and Colorimetric Analysis of Acanthosis Nigricans in Patients With Hyperinsulinemia
Henry Ford Health System 9 participants Est. completion 2012-06 1 siteOther conditions: Acanthosis Nigricans, Hyperinsulinemia, Spectroscopic AnalysisView official trial listing → -
Completed NCT NCT01128621
A Study in Type 2 Diabetic Subjects on Stable Metformin Therapy to Investigate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Co-administering Single and Multiple Oral Doses of GSK1292263
Not yet reported GlaxoSmithKline 66 participants Est. completion 2010-04-12 2 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT01140438
Treatment of Latent Autoimmune Diabetes of the Adult
Not yet reported Norwegian University of Science and Technology 64 participants Est. completion 2018-11 1 siteOther conditions: DiabetesView official trial listing → -
Completed NCT NCT01144728
Initiation and Titration of Amaryl
Not yet reported Sanofi 172 participants Est. completion 2010-12 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01144975
Study of the Safety and Biologic Activity of XOMA 052 in Subjects With Type 2 Diabetes Mellitus
Not yet reported XOMA (US) LLC 76 participants Est. completion 2011-10 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT01159600
Efficacy and Safety Study With Empagliflozin (BI 10773) vs. Placebo as add-on to Metformin or Metformin Plus Sulfonylurea Over 24 Weeks in Patients With Type 2 Diabetes
Not yet reported Boehringer Ingelheim 1504 participants 148 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT01160042
Bioequivalence Study of Metformin Hydrochloride Tablets 1000 mg Tablets of Dr. Reddy's Laboratories Limited Under Fasting Condition
Not yet reported Dr. Reddy's Laboratories Limited 54 participants Est. completion 2005-04 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Status unknown NCT NCT01162772
Influence of DPP-4 on Inflammatory Parameters in Diabetics: Gender Aspects
Medical University of Vienna 80 participants 1 siteType 2 diabetes Other conditions: Cardiovascular Risk, Endothelial DysfunctionView official trial listing → -
Terminated NCT NCT01167738
Combination Chemotherapy With or Without Metformin Hydrochloride in Treating Patients With Metastatic Pancreatic Cancer
Not yet reported IRCCS San Raffaele 60 participants Est. completion 2015-04 1 siteOther conditions: Pancreatic CancerView official trial listing → -
Completed NCT NCT01175473
Effects of Lixisenatide Compared to Liraglutide on the Postprandial Plasma Glucose in Patients With Type 2 Diabetes
Not yet reported Sanofi 148 participants Est. completion 2010-11 7 sitesType 2 diabetesView official trial listing → -
Terminated NCT NCT01177709
Metformin for Weight Loss in Schizophrenia
Not yet reported Nathan Kline Institute for Psychiatric Research 12 participants Est. completion 2011-04 1 siteOther conditions: Schizophrenia, ObesityView official trial listing → -
Completed NCT NCT01192152
Bioequivalence Study of the Fixed Dose Combination of 5 mg Saxagliptin/1000 mg Metformin XR (Manufactured in Mt Vernon, IN) Relative to 5 mg of Onglyza and 2 × 500 mg Glucophage XR
Not yet reported AstraZeneca 30 participants Est. completion 2009-12 1 site Stand-aloneOther conditions: Diabetes MellitusView official trial listing → -
Completed NCT NCT01204294
Comprehensive Add on Study in Japan
Not yet reported Boehringer Ingelheim 574 participants Est. completion 2012-01 43 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT01204580
ADIponectin and Asymmetric Dimethylarginine (ADMA) Level in Type-2 Diabetes Patients After 12 Weeks of Treatment With GlimepiRide And Metformin Fixed Dose Combination
Not yet reported Sanofi 40 participants Est. completion 2012-03 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01206153
Metformin for Treatment Antipsychotic Induced Amenorrhea in Female Schizophrenic Patients
Not yet reported Central South University 84 participants Est. completion 2010-03 1 siteOther conditions: AmenorrheaView official trial listing → -
Status unknown NCT NCT01206647
Investigation of a Switch From Insulin Therapy to a Metformin & Saxagliptin Combination in Patients With Type 2 Diabetes Mellitus
Not yet reported ikfe-CRO GmbH 120 participants Est. completion 2011-02 7 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT01210001
Efficacy and Safety of Empagliflozin (BI 10773) in Type 2 Diabetes Patients on a Background of Pioglitazone Alone or With Metformin
Not yet reported Boehringer Ingelheim 499 participants 68 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT01210911
Metformin Combined With Chemotherapy for Pancreatic Cancer
Not yet reported Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) 120 participants Est. completion 2014-04 1 siteOther conditions: Locally Advanced Pancreatic Cancer, Metastatic Pancreatic CancerView official trial listing → -
Completed NCT NCT01215331
Gestational Diabetes: Insulin or Oral Hypoglycemic Agents?
Not yet reported Université de Sherbrooke 73 participants Est. completion 2016-05 1 site Stand-aloneOther conditions: Gestational Diabetes MellitusView official trial listing → -
Completed NCT NCT01217073
A Dose-Range Finding Study in Participants With Type 2 Diabetes (MK-3102-006)
Not yet reported Merck Sharp & Dohme LLC 685 participants Est. completion 2013-04-01Type 2 diabetesView official trial listing → -
Completed NCT NCT01217892
Evaluation of Dapagliflozin Taken Twice-daily
Not yet reported AstraZeneca 400 participants Est. completion 2011-08 55 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT01219582
GLucobay M OBservation Study for Efficacy and Safety in Treatment of Type-2 Diabetes Patients
Bayer 9364 participants Est. completion 2012-12 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT01221519
A Relative Bioavailability Study Measuring the Extent and Rate of Absorption of Different Tablet Formulations of AZD1656 in Type 2 Diabetes Mellitus (T2DM) Patients
Not yet reported AstraZeneca 20 participants Est. completion 2011-01 1 siteType 2 diabetes Other conditions: High Blood SugarView official trial listing → -
Completed NCT NCT01224366
Efficacy and Safety of Vildagliptin as add-on Therapy to Insulin in Patients With Type 2 Diabetes Mellitus
Not yet reported Novartis 448 participants Est. completion 2011-10 66 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT01233622
Safety and Efficacy of Galvus as add-on Therapy to Metformin Plus Glimepiride
Not yet reported Novartis 317 participants Est. completion 2011-11 55 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT01234649
Combined Liraglutide and Metformin Therapy in Women With Previous Gestational Diabetes Mellitus (GDM)
Not yet reported Woman's 153 participants Est. completion 2019-06-14 1 siteType 2 diabetesMetabolic syndromePrediabetes Other conditions: Gestational Diabetes Mellitus, Disorder of Glucose RegulationView official trial listing → -
Completed NCT NCT01238978
Phase 4 Study in the Elderly Patients With T2DM
Not yet reported Novartis 46 participants Est. completion 2011-12 15 sitesType 2 diabetes Other conditions: ElderlyView official trial listing → -
Completed NCT NCT01241448
A Study of LY2409021 in Patients With Type 2 Diabetes
Not yet reported Eli Lilly and Company 263 participants Est. completion 2012-03 40 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01241669
Randomized, Placebo-controlled Study to Evaluate Effects of E5555 on Renal Function Parameters and OCT2 Activity
Not yet reported Eisai Inc. 104 participants 1 siteOther conditions: Healthy SubjectsView official trial listing → -
Status unknown NCT NCT01245166
A Phase III Randomized, Double-blind, Parallel-group Study to Evaluate the Efficacy and Safety of Acarmet (Metformin HCl 500 mg Plus Acarbose 50 mg Tablets) Versus Acarbose Alone in Subjects With Type 2 Diabetes Mellitus
Not yet reported Lotus Pharmaceutical 220 participants Est. completion 2011-12 1 siteType 2 diabetes Other conditions: The Objectives of the Study is to Evaluate the Efficacy and Safety of Acarmet (Metformin HCl 500 mg, Plus Acarbose 50 mg Tablets) Thrice Daily Versus Acarbose 50 mg Thrice Daily Over 16 Weeks inView official trial listing → -
Completed NCT NCT01249677
Chronic Reduction of Fasting Glycaemia With Insulin Glargine Improves First and Second Phase Insulin Secretion in Patients With Type 2 Diabetes
Not yet reported Ruhr University of Bochum 14 participants Est. completion 2010-05 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT01283308
A Randomized Trial of Diabetes Prevention Through Lifestyle Change in India
Not yet reported Emory University 599 participants Est. completion 2013-11 1 siteType 2 diabetesView official trial listing → -
Status unknown NCT NCT01286233
Study of Biomarkers Associated With Fatigue in Patients With Early-Stage Breast Cancer Treated With Metformin or Placebo on NCIC-CTG-MA.32
NSABP Foundation Inc 394 participants Est. completion 2016-09 256 sitesOther conditions: Breast Cancer, Depression, Fatigue, Sleep DisordersView official trial listing → -
Completed NCT NCT01289119
Efficacy and Safety of Alogliptin in Participants With Type 2 Diabetes
Not yet reported Takeda 506 participants Est. completion 2011-12 21 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT01290575
Multiple Ascending Dose Study of BMS-820132 in Patients With Type 2 Diabetes
Not yet reported Bristol-Myers Squibb 67 participants Est. completion 2011-11 5 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT01292993
A Study to Evaluate the Interaction of LX4211 and Metformin in Healthy Subjects
Not yet reported Lexicon Pharmaceuticals 18 participants 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT01298518
A Multiple Dose Study Of PF-04620110 In Type 2 Diabetes Patients
Not yet reported Pfizer 48 participants Est. completion 2011-05 3 sitesType 2 diabetesView official trial listing → -
Withdrawn NCT NCT01302002
The Use of Metformin in Early Breast Cancer Patients Pre-Surgery
Not yet reported Instituto Nacional de Cancer, Brazil Est. completion 2016-02 1 site Stand-aloneOther conditions: Breast CancerView official trial listing → -
Withdrawn NCT NCT01305551
BE Study of the Fixed Dose Combination of 5 mg Saxagliptin and 500 mg Metformin HCl XR Tablet Relative to a 5 mg Saxagliptin (Onglyza™) Tablet and a 500 mg Metformin HCl XR (Glifage® XR Marketed in Brazil by Merck S.A.) Tablet Co-Administered to Healthy Subjects in the Fasted and Fed States
Not yet reported AstraZeneca Est. completion 2011-03 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01306214
Safety and Efficacy of BI 10773 as add-on to Insulin Regimen in Patients With Type 2 Diabetes Mellitus
Not yet reported Boehringer Ingelheim 566 participants Est. completion 2013-04 103 sitesType 2 diabetes Other conditions: ObesityView official trial listing → -
Completed NCT NCT01324180
Vincristine, Dexamethasone, Doxorubicin, and PEG-asparaginase (VPLD) and Metformin for Relapsed Childhood Acute Lymphoblastic Leukemia (ALL)
Not yet reported H. Lee Moffitt Cancer Center and Research Institute 14 participants Est. completion 2017-07-27 5 sitesOther conditions: Acute Lymphoblastic LeukemiaView official trial listing → -
Completed NCT NCT01329016
Glyburide and Metformin for Gestational Diabetes Mellitus (GDM)
Not yet reported, Not yet reported Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) 177 participants Est. completion 2015-02-28 4 sitesOther conditions: Gestational Diabetes MellitusView official trial listing → -
Terminated NCT NCT01333852
Metformin Plus Paclitaxel for Metastatic or Recurrent Head and Neck Cancer
Not yet reported Lucas Vieira dos Santos 45 participants Est. completion 2014-04 1 siteOther conditions: Head and Neck Neoplasms, Squamous Cell CarcinomaView official trial listing → -
Completed NCT NCT01340664
An Efficacy, Safety, and Tolerability Study of Canagliflozin in the Treatment of Patients With Type 2 Diabetes Mellitus With Inadequate Glycemic Control on Metformin Monotherapy
Not yet reported Janssen Research & Development, LLC 279 participants Est. completion 2012-04 61 sites Stand-aloneType 2 diabetesView official trial listing → -
Status unknown NCT NCT01342042
The Safety,Preliminary Pharmacodynamics and Pharmacokinetics Study of rExenatide-4 in Chinese Type 2 Diabetes Mellitus
Not yet reported CSPC ZhongQi Pharmaceutical Technology Co., Ltd. 36 participants Est. completion 2011-12 1 siteType 2 diabetesView official trial listing → -
Status unknown NCT NCT01342744
Metformin in Postmenopausal Women With Metabolic Syndrome
Not yet reported Mahidol University 40 participants Est. completion 2012-03 1 siteMetabolic syndromeView official trial listing → -
Withdrawn NCT NCT01352026
Evaluation of Metformin Activity in Addition to Conventional Treatment of Grade II or III Pulmonary Arterial Hypertension (PAH)
Not yet reported Nantes University Hospital 2 sitesOther conditions: Pulmonary Arterial HypertensionView official trial listing → -
Completed NCT NCT01357135
An Observational Study of Type II Diabetics Treated With Dual Therapy With or Without Sitagliptin (Januvia®/Xelevia®, MK-0431-201)
Merck Sharp & Dohme LLC 3453 participants Est. completion 2013-08-31Type 2 diabetesView official trial listing → -
Status unknown NCT NCT01364675
Primary Prevention of Cardiovascular Disease (CVD) in Pre-diabetic & Pre-hypertensive Subjects
Not yet reported Ramathibodi Hospital 8900 participants Est. completion 2016-12 1 sitePrediabetes Other conditions: Pre-hypertensionView official trial listing → -
Completed NCT NCT01365091
Bioequivalence Study of Fixed-dose Combinations and Coadministered Individual Tablets of Saxagliptin/Metformin-Brazil
Not yet reported AstraZeneca 112 participants Est. completion 2011-11 1 site Stand-aloneType 2 diabetesView official trial listing → -
Status unknown NCT NCT01366391
Therapeutic Monitoring of Metformin in Women With Polycystic Ovary Syndrome
Not yet reported Biocinese 24 participants Est. completion 2011-10 1 siteOther conditions: Polycystic Ovary SyndromeView official trial listing → -
Completed NCT NCT01381900
A Efficacy, Safety, and Tolerability Study of Canagliflozin in Patients With Type 2 Diabetes Mellitus With Inadequate Glycemic Control on Metformin Alone or in Combination With a Sulphonylurea
Not yet reported Janssen Research & Development, LLC 678 participants Est. completion 2012-11 25 sites Stand-aloneType 2 diabetesView official trial listing → -
Status unknown NCT NCT01389778
Polycystic Ovary Syndrome Genetics and Treatment Response
Not yet reported Massachusetts General Hospital 200 participants Est. completion 2019-10 1 site Stand-aloneOther conditions: Polycystic Ovary SyndromeView official trial listing → -
Completed NCT NCT01396564
Pioglitazone and Metformin in Diabetic Children
Not yet reported, Not yet reported Coordinación de Investigación en Salud, Mexico 56 participants Est. completion 2011-07 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT01399645
Study of Liraglutide Versus Insulin on Liver Fat Fraction in Patients With Type 2 Diabetes
Not yet reported Centre hospitalier de l'Université de Montréal (CHUM) 35 participants Est. completion 2014-06 1 siteMASLDMASHType 2 diabetesView official trial listing → -
Completed NCT NCT01410604
Adipokines in Obese Adolescents With Insulin Resistance
Not yet reported Hospital Regional de Alta Especialidad del Bajio 31 participants Est. completion 2010-03 2 sitesOther conditions: ObesityView official trial listing → -
Completed NCT NCT01426399
Pharmacokinetic/Pharmacodynamic Drug-drug Interaction of LC15-0444 and Metformin After Oral Administration in Healthy Male Subjects
Not yet reported LG Life Sciences 30 participants Est. completion 2011-12 1 siteOther conditions: HealthyView official trial listing → -
Status unknown NCT NCT01426737
The Swiss Glucose Variability Study
Not yet reported University of Zurich 50 participants Est. completion 2013-01 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT01426802
Vildagliptin 50 mg Twice Daily in Patients With Type 2 Diabetes Mellitus Inadequately Controlled With Metformin
Not yet reported Novartis Pharmaceuticals 150 participants Est. completion 2011-04 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT01427595
Effect of Metformin on Sensitivity of the GnRH Pulse Generator to Suppression by Estradiol and Progesterone
Not yet reported University of Virginia 25 participants Est. completion 2015-01-17 1 site Stand-aloneOther conditions: Polycystic Ovary Syndrome, HyperandrogenismView official trial listing → -
Completed NCT NCT01429506
Efficacy of Laparoscopic Sleeve Gastrectomy and Intensive Medical Management in Obese Type 2 Diabetes
Not yet reported Post Graduate Institute of Medical Education and Research, Chandigarh 30 participants Est. completion 2012-08 1 siteOther conditions: Diabetes Mellitus, ObesityView official trial listing → -
Completed NCT NCT01433913
Metformin Hydrochloride in Treating Patients With Prostate Cancer Undergoing Surgery
Not yet reported National Cancer Institute (NCI) 20 participants Est. completion 2014-04 3 sites Stand-aloneOther conditions: Adenocarcinoma of the Prostate, Recurrent Prostate Cancer, Stage I Prostate Cancer, Stage IIA Prostate Cancer, Stage IIB Prostate CancerView official trial listing → -
Completed NCT NCT01437813
BIOAVAILABILITY OF Glimepiride/Extended Release Metformin (GLI/METXR): High Fat Diet Study
Not yet reported Laboratorios Silanes S.A. de C.V. 24 participants Est. completion 2011-03 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Status unknown NCT NCT01438190
Metformin in Step-down Regimen Versus Conventional Low Dose Step-up Protocol in Patients With PCOS Undergoing IVF
Not yet reported University of Modena and Reggio Emilia 120 participants Est. completion 2014-12 1 site Stand-aloneOther conditions: Infertility, PCOSView official trial listing → -
Terminated NCT NCT01440127
Impact of Pretreatment With Metformin on Colorectal Cancer Stem Cells (CCSC) and Related Pharmacodynamic Markers
Not yet reported Tufts Medical Center 9 participants Est. completion 2012-10 1 site Stand-aloneOther conditions: Colon CancerView official trial listing → -
Completed NCT NCT01441869
Study in Healthy Subjects to Measure Amount of Drug in Blood After Dosing With Different Saxagliptin / Metformin Produc
Not yet reported AstraZeneca 28 participants Est. completion 2011-12 1 site Stand-aloneOther conditions: Bioequivalence, Log-transformed AUCss and Cmax,ss Values for Saxagliptin and MetforminView official trial listing → -
Completed NCT NCT01443221
Pharmacokinetics of Mitiglinide and Metformin in Free Combination and Fixed-dose Combination in Healthy Male Subjects.
Not yet reported JW Pharmaceutical 24 participants Est. completion 2011-01 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT01444248
Compare the Compliance of Patients Treated With Once-daily (od) or Twice-daily (Bid) Glimepiride and Metformin Fixed Combination Therapy
Not yet reported Handok Inc. 168 participants Est. completion 2012-05 1 siteType 2 diabetesView official trial listing → -
Withdrawn NCT NCT01455909
A Study to Evaluate ITCA 650 Compared to Sitagliptin for the Treatment of Type 2 Diabetes
Not yet reported Intarcia Therapeutics Est. completion 2014-07 1 siteType 2 diabetesView official trial listing → -
Withdrawn NCT NCT01455922
A Study to Evaluate ITCA 650 Compared to Glimepiride as Add on Therapy for the Treatment of Type 2 Diabetes
Not yet reported Intarcia Therapeutics Est. completion 2014-07 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT01464437
AMG 151 Amgen Protocol Number 20100761
Not yet reported Amgen 236 participants Est. completion 2012-12 77 sitesOther conditions: Diabetes MellitusView official trial listing → -
Completed NCT NCT01475461
Phase 2 Study To Evaluate Safety And Efficacy Of Investigational Drug - PF04937319 In Patients With Type 2 Diabetes
Not yet reported Pfizer 345 participants Est. completion 2013-01 63 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT01476475
Efficacy and Safety of Insulin Glargine/Lixisenatide Fixed Combination Versus Insulin Glargine Alone on Top of Metformin in Type 2 Diabetic Patients
Not yet reported Sanofi 323 participants Est. completion 2012-12 70 sites Added to GLP-1Type 2 diabetesView official trial listing → -
Terminated NCT NCT01477853
A Study of the Co-administration of Sitagliptin and Atorvastatin in Inadequately Controlled Type 2 Diabetes Mellitus (MK-0431E-211)
Not yet reported Merck Sharp & Dohme LLC 166 participants Est. completion 2012-12-04 Stand-aloneType 2 diabetesView official trial listing → -
Withdrawn NCT NCT01478308
Metformin With Standard Taxotere and Prednisone in the Treatment of Castration Resistant Prostate Cancer
Not yet reported New Mexico Cancer Research Alliance Est. completion 2011-10Other conditions: Prostate CancerView official trial listing → -
Terminated NCT NCT01482286
Effect of Weight and Insulin Sensitivity on Reproductive Function in PCOS
Not yet reported Pennington Biomedical Research Center 32 participants Est. completion 2016-12 1 siteOther conditions: Polycystic Ovary SyndromeView official trial listing → -
Completed NCT NCT01483560
REducing With MetfOrmin Vascular Adverse Lesions in Type 1 Diabetes (REMOVAL)
Not yet reported University of Glasgow 493 participants Est. completion 2017-04-18 24 sitesOther conditions: Diabetes Mellitus, Type 1View official trial listing → -
Terminated NCT NCT01496430
Efficacy and Safety of Azilsartan Medoxomil Used in Combination With Metformin in Participants With Hypertension and Diabetes
Not yet reported Takeda 105 participants Est. completion 2013-05 68 sitesOther conditions: Hypertension, DiabetesView official trial listing → -
Withdrawn NCT NCT01510522
Evaluate Adherence to Treatment With Glucophage Sachets Versus Tablets in Diabetes Type 2 Patients Previously Treated With Metformin Tablets
Not yet reported Merck KGaA, Darmstadt, Germany Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01511198
Efficacy and Safety of Metformin and Liraglutide in Obese Subjects With Type 2 Diabetes Previously Treated With an Oral Hypoglycemic Agent
Not yet reported Novo Nordisk A/S 223 participants Est. completion 2001-10 39 sitesType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT01513590
A Trial Comparing Efficacy and Safety of Insulin Degludec/Insulin Aspart and BIAsp 30 in Insulin naïve Subjects With Type 2 Diabetes
Not yet reported Novo Nordisk A/S 394 participants Est. completion 2012-11-19 49 sitesType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT01517373
Study To Understand Efficacy And Safety Of Investigational Agent (PF-04937319) Compared To Approved Agent (Glimepiride) In Patients With Diabetes On Metformin
Not yet reported Pfizer 304 participants Est. completion 2013-01 53 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT01517412
Comparison of Lixisenatide Injected Prior to the Main Meal of the Day Versus Prior to Breakfast in Type 2 Diabetic Patients on Metformin
Not yet reported Sanofi 451 participants Est. completion 2013-05 82 sites Added to GLP-1Type 2 diabetesView official trial listing → -
Completed NCT NCT01518101
Vildagliptin Versus Liraglutide - Patient Preference After Receiving Both Medications
Not yet reported Novartis Pharmaceuticals 62 participants Est. completion 2012-10 8 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT01519674
Treatment Intensification With Biphasic Insulin Aspart 30 in Subjects With Type 2 Diabetes Inadequately Controlled on Sitagliptin and Metformin
Not yet reported Novo Nordisk A/S 582 participants Est. completion 2013-10 69 sitesType 2 diabetes Other conditions: DiabetesView official trial listing → -
Terminated NCT NCT01525225
Study of Saxagliptin, 5-Hydroxy Saxagliptin, and Metformin Concentrations/Levels in Pediatric Subjects With T2DM
Not yet reported AstraZeneca 4 participants Est. completion 2013-06 7 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT01528254
VERIFY:A Study to Compare Combination Regimen With Vildagliptin & Metformin Versus Metformin in Treatment-naïve Patients With Type 2 Diabetes Mellitus
Not yet reported Novartis Pharmaceuticals 2004 participants Est. completion 2019-04-04 227 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01535677
To Compare the Similarity of a Combination Dapagliflozin/Metformin Tablet With the Two Drugs Administered Separately
Not yet reported AstraZeneca 71 participants Est. completion 2013-07 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01540487
Pharmacokinetics of Fixed Dose Combination (FDC) Tablets of Linagliptin /Metformin
Not yet reported Boehringer Ingelheim 48 participants Est. completion 2012-06 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT01541956
Efficacy of VIldagliptin aS an Add-on Therapy to Metformin Compared to Metformin Up-TitratION in Chinese Patients With Type 2 Diabetes.(VISION)
Not yet reported Novartis Pharmaceuticals 3091 participants Est. completion 2013-12 1 siteType 2 diabetesView official trial listing → -
Status unknown NCT NCT01544751
Nonalcoholic Fatty Liver Disease (NAFLD) Pharmacological Treatment: Metformin Versus Atorvastatin
Not yet reported Prof Antonino Belfiore 150 participants Est. completion 2015-06 1 siteMASLDView official trial listing → -
Completed NCT NCT01545388
Metformin Add-on Regimen Comparison Study in Japanese Participants With Type 2 Diabetes Mellitus (MK-0431A-136)
Not yet reported Merck Sharp & Dohme LLC 337 participants Est. completion 2013-03-12 Stand-aloneType 2 diabetesView official trial listing → -
Withdrawn NCT NCT01550900
Prospective Trial of Metformin - Chemoprevention Role
Not yet reported M.D. Anderson Cancer CenterOther conditions: ColorectumView official trial listing → -
Completed NCT NCT01561976
Evaluation of Food Effect on the Pharmacokinetics of Sustained Release Metformin in Healthy Indian Volunteers
Not yet reported GlaxoSmithKline 30 participants Est. completion 2012-02-21Type 2 diabetesView official trial listing → -
Completed NCT NCT01563120
A Comparison Between Two Oral Hypoglycemics - Metformin and Glybenclamide for the Treatment of Gestational Diabetes Mellitus
Not yet reported HaEmek Medical Center, Israel 108 participants Est. completion 2014-12 1 siteOther conditions: Gestational Diabetes MellitusView official trial listing → -
Status unknown NCT NCT01565096
Effect of Adding Vildagliptin on Beta Cell Function and Cardiovascular Risk Markers in Patients With Moderate Metabolic Control During Metformin Monotherapy
Not yet reported ikfe-CRO GmbH 44 participants 1 site Stand-aloneOther conditions: Diabetes Mellitus Type IIView official trial listing → -
Status unknown NCT NCT01566799
Metformin Plus Neoadjuvant Chemotherapy in Breast Cancer
Not yet reported Instituto Nacional de Cancerologia de Mexico 60 participants Est. completion 2014-04 1 site Stand-aloneOther conditions: Locally Advanced Malignant NeoplasmView official trial listing → -
Completed NCT NCT01573377
Efficacy of Metformin and Diane-35 on PCOS Patients,a Randomized, Controlled, Prospective Clinical Trial
Not yet reported Chongqing Medical University 40 participants Est. completion 2013-02 1 siteOther conditions: Polycystic Ovary Syndrome, Insulin ResistanceView official trial listing → -
Completed NCT NCT01573949
A Pilot Study: Metformin Therapy in Heart Failure Patients With Early Diabetes or at High Risk of Developing Diabetes (Pre-Diabetes)
Not yet reported University of California, Los Angeles 7 participants Est. completion 2012-12 1 site Stand-aloneHeart failure Other conditions: DiabetesView official trial listing → -
Completed NCT NCT01581814
Effects of Drospirenone-ethinylestradiol and/or Metformin on Cardiovascular Risk in Hyperinsulinemic Women With Polycystic Ovary Syndrome
Not yet reported Catholic University of the Sacred Heart 99 participants Est. completion 2012-03 1 siteOther conditions: Polycystic Ovary SyndromeView official trial listing → -
Completed NCT NCT01584232
A Study of Dulaglutide in Japanese Participants With Type 2 Diabetes Mellitus
Not yet reported Eli Lilly and Company 361 participants Est. completion 2013-07 15 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01587378
Metformin to Prevent Late Miscarriage and Preterm Delivery in Women With Polycystic Ovary Syndrome
Not yet reported Norwegian University of Science and Technology 489 participants Est. completion 2017-10-31 13 sitesOther conditions: Pregnancy, Polycystic Ovary SyndromeView official trial listing → -
Completed NCT NCT01589367
Neoadjuvant Letrozole Plus Metformin vs Letrozole Plus Placebo for ER-positive Postmenopausal Breast Cancer
Not yet reported Seoul National University Hospital 208 participants Est. completion 2018-08 1 siteOther conditions: Hormone Receptor Positive Malignant Neoplasm of BreastView official trial listing → -
Withdrawn NCT NCT01593137
A Long-term Trial to Compare the Effects of Liraglutide and Sulphonylurea (Glimepiride) Both in Combination With Metformin on Clinical, Endothelial and Image Markers of Cardiovascular Risk in Patients With Type 2 Diabetes
Not yet reported Fundación Fernández-Cruz Est. completion 2014-12 1 site Added to GLP-1Type 2 diabetesView official trial listing → -
Completed NCT NCT01593371
Comparison of Metformin and Pioglitazone Effects on Adipokines Concentrations in Newly Diagnosed Type 2 Diabetes Patients
Not yet reported Tehran University of Medical Sciences 98 participants Est. completion 2012-01 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT01612741
Diabetes Treatment With Glucobay in Combination With Metformin
Bayer 19509 participants Est. completion 2009-01 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT01624259
A Study Comparing the Effect of Dulaglutide With Liraglutide in Type 2 Diabetes
Not yet reported Eli Lilly and Company 599 participants Est. completion 2013-11 57 sitesType 2 diabetesView official trial listing → -
Terminated NCT NCT01627067
Exemestane-RAD001-Metformin
Not yet reported M.D. Anderson Cancer Center 23 participants Est. completion 2019-02-01 1 site Stand-aloneOther conditions: Breast CancerView official trial listing → -
Completed NCT NCT01632163
Assessment of the Efficacy and Safety of Lixisenatide in Patients With Type 2 Diabetes Insufficiently Controlled With Basal Insulin +/- Metformin
Not yet reported Sanofi 447 participants Est. completion 2015-05 51 sites Added to GLP-1Type 2 diabetesView official trial listing → -
Completed NCT NCT01649297
A 16 Weeks Study on Efficacy and Safety of Two Doses of Empagliflozin (BI 10773) (Once Daily Versus Twice Daily) in Patients With Type 2 Diabetes Mellitus and Preexisting Metformin Therapy
Not yet reported Boehringer Ingelheim 983 participants Est. completion 2013-12 139 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT01650181
Effects of Siliphos-Selenium-Methionine-Alpha Lipoic Acid in Patients With Fatty Liver and Non-alcoholic Steatohepatitis
Not yet reported Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran 50 participants Est. completion 2014-06 1 siteOther conditions: Liver DiseaseView official trial listing → -
Terminated NCT NCT01654640
The Effect of Metformin on Obesity and Metabolic Disturbance in Patients Taking Clozapine
Not yet reported Seoul National University Hospital 15 participants Est. completion 2015-04 1 siteOther conditions: SchizophreniaView official trial listing → -
Completed NCT NCT01664624
Roflumilast Plus Alogliptin Proof-of-Mechanism Study in Type2 Diabetes
Not yet reported AstraZeneca 40 participants Est. completion 2012-11 2 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT01681693
Effect of Genetic Variants in MATE1 and OCT3 on the Pharmacodynamics of Metformin in African Americans
Not yet reported University of California, San Francisco 33 participants Est. completion 2013-07 1 site Stand-aloneType 2 diabetes Other conditions: HealthyView official trial listing → -
Completed NCT NCT01685762
Metformin for the Treatment of Endometrial Hyperplasia
Not yet reported UNC Lineberger Comprehensive Cancer Center 18 participants Est. completion 2015-12-01 3 sitesOther conditions: Endometrial Hyperplasia, Endometrial Hyperplasia Without AtypiaView official trial listing → -
Completed NCT NCT01690091
Cardioprotective and Metabolic Effects of Metformin in Patients With Heart Failure and Diabetes
Not yet reported, Not yet reported Institute for Clinical and Experimental Medicine 40 participants Est. completion 2016-12 1 site Stand-aloneHeart failure Other conditions: Insulin ResistanceView official trial listing → -
Completed NCT NCT01710527
BE Study of Metformin GSK 500mg
Not yet reported GlaxoSmithKline 32 participants Est. completion 2012-05-18Other conditions: Diabetic FootView official trial listing → -
Completed NCT NCT01710540
BE Study of Metformin GSK 850mg
Not yet reported GlaxoSmithKline 32 participants Est. completion 2012-08Other conditions: Diabetic FootView official trial listing → -
Terminated NCT NCT01717482
Metformin as a Chemoprevention Agent in Non-small Cell Lung Cancer
Not yet reported Mayo Clinic 6 participants Est. completion 2019-05-22 1 siteOther conditions: Lung Neoplasms, Carcinoma, Non-Small-Cell LungView official trial listing → -
Status unknown NCT NCT01717911
ß-Cell Function and Glycemic Control in Newly Diagnosed Type 2 Diabetic Patients With Moderate Hyperglycemia
Not yet reported Taipei Veterans General Hospital, Taiwan 160 participants Est. completion 2018-12 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT01726764
Interaction Between St John's Wort and Metformin?
Not yet reported University of Southern Denmark 20 participants Est. completion 2014-05 1 site Stand-aloneType 2 diabetes Other conditions: DepressionView official trial listing → -
Completed NCT NCT01733459
Efficacy and Safety of DLBS3233 in Subjects With Polycystic Ovary Syndrome (PCOS)
Not yet reported Dexa Medica Group 124 participants Est. completion 2018-06 2 sitesOther conditions: Polycystic Ovary Syndrome (PCOS)View official trial listing → -
Withdrawn NCT NCT01733836
Prostate Cancer Active Surveillance Metformin Trial
Not yet reported University Health Network, Toronto Est. completion 2014-10 1 siteOther conditions: Prostate CancerView official trial listing → -
Completed NCT NCT01754142
Korean Post-marketing Surveillance for Kombiglyze XR®
AstraZeneca 755 participants Est. completion 2016-09-01 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT01755156
A Study to Evaluate the Safety, Tolerability, and Efficacy of the Addition of Omarigliptin (MK-3102) to Participants With Type 2 Diabetes Mellitus Who Have Inadequate Glycemic Control on Metformin Therapy (MK-3102-024)
Not yet reported Merck Sharp & Dohme LLC 402 participants Est. completion 2016-03-16 Stand-aloneType 2 diabetesView official trial listing → -
Terminated NCT NCT01756105
Efficacy of Metformin in Achieving Glycaemia Goals as Recommended for the Treatment of Gestational Diabetes in Non Obese Women
Not yet reported University Hospital, Strasbourg, France 84 participants Est. completion 2018-06 5 sites Stand-aloneOther conditions: Gestational Diabetes, Metformin, Treatment, Oxidative StressView official trial listing → -
Completed NCT NCT01757587
Galvus (Vildagliptin) vs Placebo in Combination With Metformin and Insulin
Not yet reported Centre d'Etudes et de Recherche pour l'Intensification du Traitement du Diabète 39 participants Est. completion 2015-03 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT01765894
Influence of Moderate Exercise on Blood Glucose in Type 2 Diabetics and Healthy Controls
University of Copenhagen 24 participants Est. completion 2013-11 1 siteType 2 diabetesView official trial listing → -
Status unknown NCT NCT01771185
Metabolic Effects of Gastrointestinal Surgery in T2DM
Not yet reported University of Sao Paulo 24 participants Est. completion 2013-12Type 2 diabetesView official trial listing → -
Completed NCT NCT01775579
Evaluating a Pharmacokinetic Drug Interaction Between Metformin Hydrochloride and Rosuvastatin Calcium
Not yet reported Hanmi Pharmaceutical Company Limited 36 participants Est. completion 2013-06 1 siteOther conditions: Diabetes MellitusView official trial listing → -
Completed NCT NCT01780051
A Pharmacokinetic Study to Compare Co-administration of Repaglinide and Metformin HCl to Administration of Combination Preparation of Those Two Components
Not yet reported Dalim BioTech Co., Ltd. 48 participants Est. completion 2013-04 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT01786707
Autologous Stem Cell and Hyperbaric Oxygen Therapy in Type 2 Diabetes Mellitus
Not yet reported, Not yet reported Rodolfo Alejandro 2 participants Est. completion 2013-03 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01787396
Phase III Trial to Evaluate the Efficacy and Safety of Initial Combination Therapy With Gemigliptin 50mg q.d and Metformin q.d
Not yet reported LG Life Sciences 433 participants Est. completion 2015-03 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01796028
Metformin-Docetaxel Association in Metastatic Hormone-refractory Prostate Cancer
Not yet reported Centre Antoine Lacassagne 100 participants Est. completion 2018-05-31 1 site Stand-aloneOther conditions: Prostatic NeoplasmsView official trial listing → -
Completed NCT NCT01800227
Bioequivalence Study of Torrent Pharmaceuticals Ltd's Pioglitazone Hydrochloride and Metformin Hydrochloride Tablets Under Fasting Conditions
Not yet reported Torrent Pharmaceuticals Limited 1 siteOther conditions: HealthyView official trial listing → -
Completed NCT NCT01809327
A Study to Evaluate the Effectiveness, Safety, and Tolerability of Canagliflozin in Combination With Metformin in the Treatment of Patients With Type 2 Diabetes Mellitus With Inadequate Glycemic Control With Diet and Exercise
Not yet reported Janssen Research & Development, LLC 1186 participants Est. completion 2014-12-02 129 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01813929
Effect of Metformin on Vascular and Mitochondrial Function in Type 1 Diabetes
Not yet reported University of Colorado, Denver 23 participants Est. completion 2017-03-24 1 site Stand-aloneOther conditions: Type 1 DiabetesView official trial listing → -
Completed NCT NCT01825798
Treatment of Overweight Induced by Antipsychotic Medication in Young People With Autism Spectrum Disorders (ASD)
Not yet reported Holland Bloorview Kids Rehabilitation Hospital 60 participants Est. completion 2015-10 4 sitesOther conditions: Overweight, Autism Spectrum DisorderView official trial listing → -
Completed NCT NCT01831661
Bioequivalence Study of Metformin Hydrochloride Extended-Release Tablets USP 750 mg Under Fasting Condition
Not yet reported IPCA Laboratories Ltd. 48 participants Est. completion 2013-02 1 site Stand-aloneOther conditions: FastingView official trial listing → -
Completed NCT NCT01840007
Pilot Study Evaluating the Efficacy and Safety of Metformin in Melanoma
Not yet reported Centre Hospitalier Universitaire de Nice 20 participants Est. completion 2015-11-18 2 sitesOther conditions: Metastatic Melanoma (Stage IIIC Non-résécable or no Surgically Curable or Stage IV With Classification AJCC)View official trial listing → -
Completed NCT NCT01845077
Relative Bioavailability of 2 Fixed Dose Combinations of Linagliptin/Metformin Compared With Single Tablets
Not yet reported Boehringer Ingelheim 72 participants Est. completion 2013-08 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT01845831
Sitagliptin Therapy in Hospitalized Patients With Type 2 Diabetes
Not yet reported Emory University 292 participants Est. completion 2016-04 5 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT01850615
Efficacy and Safety of FIAsp in a Basal-bolus Regimen Versus Basal Insulin Therapy, Both in Combination With Metformin in Adult Subjects With Type 2 Diabetes
Not yet reported Novo Nordisk A/S 323 participants Est. completion 2014-11-17 58 sites Stand-aloneType 2 diabetes Other conditions: DiabetesView official trial listing → -
Status unknown NCT NCT01855763
Metformin Treatment in Gestational Diabetes and Noninsulin Dependent Diabetes in Pregnancy in a Developing Country
Not yet reported, Not yet reported Dow University of Health Sciences 300 participants Est. completion 2013-12Type 2 diabetes Other conditions: Gestational Diabetes, PregnancyView official trial listing → -
Completed NCT NCT01856907
Sitagliptin + Metformin Compared to Metformin Monotherapy and Placebo in Women With a Recent GDM
Not yet reported Woman's 36 participants Est. completion 2017-09-28 1 site Stand-aloneOther conditions: Disorder of Glucose RegulationView official trial listing → -
Completed NCT NCT01859793
Effects of Sitagliptin on Endothelial Function in Type 2 Diabetes on Background Metformin Therapy
Not yet reported Medical College of Wisconsin 38 participants Est. completion 2016-07 1 siteOther conditions: Diabetes, AtherosclerosisView official trial listing → -
Status unknown NCT NCT01864096
The Metformin Active Surveillance Trial (MAST) Study
Not yet reported University Health Network, Toronto 408 participants Est. completion 2024-08 12 sites Stand-aloneOther conditions: Prostate CancerView official trial listing → -
Completed NCT NCT01864174
Phase 4: Investigational Study to Evaluate Metformin XR Monotherapy Versus Metformin IR Monotherapy in Subjects With Type 2 Diabetes
Not yet reported Bristol-Myers Squibb 1736 participants Est. completion 2016-06-01 156 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT01869621
Study of Metformin Pharmacogenetics in Twins
Not yet reported University of Southern Denmark 34 participants Est. completion 2014-10 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT01874080
Bioequivalence Study
Not yet reported AstraZeneca 56 participants Est. completion 2013-07 1 site Stand-aloneOther conditions: DiabetesView official trial listing → -
Completed NCT NCT01879293
Metformin Reduces Left Ventricular Mass in Patients With Ischemic Heart Disease
Not yet reported Wuhan General Hospital of Guangzhou Military Command 120 participants Est. completion 2015-08 1 siteOther conditions: Left Ventriclar MassView official trial listing → -
Completed NCT NCT01881828
Metformin Therapy for Overweight Adolescents With Type 1 Diabetes
Not yet reported Jaeb Center for Health Research 164 participants Est. completion 2014-12 1 siteOther conditions: Type 1 DiabetesView official trial listing → -
Completed NCT NCT01889667
Safety, Pharmacokinetics (PK) and Pharmacodynamics (PD) of Multiple Oral Bedtime Doses of ORMD-0801 in Adult Patients With Type 2 Diabetes Mellitus (T2DM)
Not yet reported Oramed, Ltd. 30 participants Est. completion 2013-11 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT01890122
Efficacy and Safety of Alogliptin and Metformin Fixed-Dose Combination in Participants With Type 2 Diabetes
Not yet reported Takeda 647 participants Est. completion 2015-10 45 sites Stand-aloneOther conditions: Diabetes MellitusView official trial listing → -
Completed NCT NCT01890629
Effects of Gemigliptin Versus Sitagliptin or Glimepiride With Metformin on Glucose Variability(MAGE, Glucose SD) Patients With Type 2 DM(STABLE Study)
Not yet reported LG Life Sciences 69 participants Est. completion 2014-08 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01892020
Investigating Efficacy and Safety of Biphasic Insulin Aspart 50 Twice Daily Versus Biphasic Human Insulin 50 Twice Daily Both in Combination With Metformin in Chinese Subjects With Type 2 Diabetes Mellitus
Not yet reported Novo Nordisk A/S 161 participants Est. completion 2014-05 1 site Stand-aloneType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT01899430
Polycystic Ovary Syndrome and Liraglutide
Not yet reported University Medical Centre Ljubljana 32 participants Est. completion 2013-04 1 siteOther conditions: PCOS, ObesityView official trial listing → -
Terminated NCT NCT01901224
Metformin, Muscle Energetics, and Vascular Function in Older Adults With Peripheral Artery Disease
Not yet reported Brigham and Women's Hospital 2 participants Est. completion 2015-06 1 site Stand-aloneOther conditions: Peripheral Artery DiseaseView official trial listing → -
Active, not recruiting NCT NCT01905046
Metformin Hydrochloride in Preventing Breast Cancer in Patients With Atypical Hyperplasia or In Situ Breast Cancer
Not yet reported Alliance for Clinical Trials in Oncology 86 participants Est. completion 2026-11 27 sitesOther conditions: Atypical Ductal Breast Hyperplasia, BRCA1 Mutation Carrier, BRCA2 Mutation Carrier, Ductal Breast Carcinoma in Situ, Lobular Breast Carcinoma in SituView official trial listing → -
Completed NCT NCT01907854
Efficacy and Safety of Switching From Sitagliptin to Liraglutide in Subjects With Type 2 Diabetes Not Achieving Adequate Glycaemic Control on Sitagliptin and Metformin
Not yet reported Novo Nordisk A/S 407 participants Est. completion 2015-06-15 106 sites Added to GLP-1Type 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT01915550
Metformin as Adjuvant to Insulin Therapy in Insulin-resistant Diabetes Mellitus With Pregnancy
Not yet reported Ain Shams University 90 participants Est. completion 2013-02 1 siteOther conditions: Diabetes MellitusView official trial listing → -
Completed NCT NCT01917656
Efficacy and Safety of Liraglutide Versus Sulphonylurea Both in Combination With Metformin During Ramadan in Subjects With Type 2 Diabetes
Not yet reported Novo Nordisk A/S 343 participants Est. completion 2014-09-04 41 sites Added to GLP-1Type 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT01918865
Safety, Tolerability, and Efficacy of ISIS-PTP1BRx in Type 2 Diabetes
Not yet reported Ionis Pharmaceuticals, Inc. 92 participants Est. completion 2015-02 21 sites Stand-aloneType 2 diabetes Other conditions: ObeseView official trial listing → -
Terminated NCT NCT01929811
NeoMET Study in Neoadjuvant Treatment of Breast Cancer
Not yet reported Shanghai Jiao Tong University School of Medicine 92 participants Est. completion 2020-06 2 sitesOther conditions: pCR Rate, BCT Rate, SafetyView official trial listing → -
Completed NCT NCT01929863
Study to Investigate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of GSK2330672 in Type 2 Diabetes Patients Taking Metformin
Not yet reported GlaxoSmithKline 16 participants Est. completion 2013-11-21 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01930188
Efficacy and Safety of Semaglutide Once-weekly Versus Sitagliptin Once-daily as add-on to Metformin and/or TZD in Subjects With Type 2 Diabetes
Not yet reported Novo Nordisk A/S 1231 participants Est. completion 2015-10-12 141 sitesType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT01937598
Antidiabetic Effects of Adding a DPP-4 Inhibitor to Pre-Existing Treatment With an Incretin Mimetic in Patients With T2D
Not yet reported Michael A. Nauck 16 participants Est. completion 2015-06 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT01952145
A Trial Comparing the Efficacy and Safety of Insulin Degludec/Liraglutide Versus Insulin Glargine in Subjects With Type 2 Diabetes Mellitus
Not yet reported Novo Nordisk A/S 557 participants Est. completion 2014-11-04 91 sitesType 2 diabetes Other conditions: DiabetesView official trial listing → -
Withdrawn NCT NCT01961388
Study to Assess the Dietary Carbohydrate Content of Indian Diabetics With Special Therapeutic View on Effectiveness of Acarbose and Metformin Monotherapy
Bayer Est. completion 2017-06Other conditions: Diabetes MellitusView official trial listing → -
Completed NCT NCT01963130
Does Vildagliptin Affect Portal Vein Pressure In Patients With Type 2 Diabetes Mellitus? A Cross Sectional Study
Bezmialem Vakif University 97 participants Est. completion 2013-07 1 siteOther conditions: Drug Mechanism, Drug UsageView official trial listing → -
Completed NCT NCT01963663
Metformin and Pioglitazone Effects on YKL-40 Concentrations in Type 2 Diabetes Patients
Not yet reported Tehran University of Medical Sciences 84 participants Est. completion 2013-04 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT01966978
The Effect of Simple Basal Insulin Titration, Metformin Plus Liraglutide for Type 2 Diabetes With Very Elevated HbA1c - The SIMPLE Study
Not yet reported University of Texas Southwestern Medical Center 157 participants Est. completion 2017-12 1 siteType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT01969318
Efficacy and Safety Study of SP2086 in Combination With Metformin in Patients With Type 2 Diabetes
Not yet reported Jiangsu HengRui Medicine Co., Ltd. 120 participants Est. completion 2012-11 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT01973231
Efficacy and Safety of Liraglutide Versus Lixisenatide as add-on to Metformin in Subjects With Type 2 Diabetes
Not yet reported Novo Nordisk A/S 404 participants Est. completion 2014-11 61 sitesType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT01973933
Clinical Trial to Investigate the Pharmacokinetic/Pharmacodynamic Drug-Drug Interaction of Pyrimethamine and Metformin IR
Not yet reported Seoul National University Hospital 20 participants 1 siteOther conditions: HealthyView official trial listing → -
Status unknown NCT NCT01974544
Prevention and Treatment Of Diabetes Complications With Gastric Surgery or Intensive Medicines
Not yet reported Pontificia Universidad Catolica de Chile 150 participants Est. completion 2016-12 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01980823
Pre-Surgical Trial of the Combination of Metformin and Atorvastatin in Newly Diagnosed Operable Breast Cancer
Not yet reported Columbia University 23 participants Est. completion 2022-12 1 site Stand-aloneOther conditions: Breast Cancer, Breast Tumors, Cancer of BreastView official trial listing → -
Withdrawn NCT NCT01984606
Efficacy and Safety of Empagliflozin Versus Sitagliptin in Patients With Type 2 Diabetes
Not yet reported Boehringer Ingelheim Est. completion 2017-02Type 2 diabetesView official trial listing → -
Completed NCT NCT01992211
Evaluating of Pharmacokinetic Profile of BCWP_C003 and Co-administration of Rosuvastatin and Metformin
Not yet reported BC World Pharm Co. Ltd. 35 participants Est. completion 2017-07-10 1 siteOther conditions: HealthyView official trial listing → -
Completed NCT NCT01995032
L-citrulline and Metformin in Duchenne's Muscular Dystrophy
Not yet reported University Hospital, Basel, Switzerland 47 participants Est. completion 2016-03 1 site Stand-aloneOther conditions: Duchenne's Muscular Dystrophy (DMD)View official trial listing → -
Completed NCT NCT02002221
Study of Efficacy and Safety of Vildagliptin as add-on Insulin Therapy in T2DM Patients
Not yet reported Novartis Pharmaceuticals 156 participants Est. completion 2015-02 31 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT02004886
A Study to Assess the Safety, Tolerability and Glucose-Lowering Efficacy of MK-0893 in Participants With Type 2 Diabetes Mellitus (MK-0893-005)
Not yet reported Merck Sharp & Dohme LLC 74 participants Est. completion 2007-02-07 Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT02006836
Glycemic Responses to Majia Pomelos in Type 2 Diabetic Patients
Not yet reported Huazhong University of Science and Technology 59 participants Est. completion 2013-12 1 siteOther conditions: DiabetesView official trial listing → -
Completed NCT NCT02027753
Efficacy and Safety of Insulin Glargine in Patients With Type 2 Diabetes With Inadequate Control on DPP-4 Inhibitor Therapy
Not yet reported Sanofi 109 participants Est. completion 2015-04 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT02028221
Phase II Study of Metformin for Reduction of Obesity-Associated Breast Cancer Risk
Not yet reported University of Arizona 151 participants Est. completion 2022-06-14 1 siteOther conditions: Breast Cancer PreventionView official trial listing → -
Completed NCT NCT02036515
Safety and Efficacy of Ertugliflozin in the Treatment of Participants With Type 2 Diabetes Mellitus Who Have Inadequate Glycemic Control on Metformin and Sitagliptin (MK-8835-006; VERTIS SITA2)
Not yet reported Merck Sharp & Dohme LLC 464 participants Est. completion 2016-06-06 Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT02039245
Multiple Dose Pharmacokinetics of Canagliflozin/Metformin 150/1,000 mg Fixed Dose Combination
Not yet reported Janssen Research & Development, LLC 12 participants Est. completion 2014-03 1 site Stand-aloneOther conditions: Healthy VolunteersView official trial listing → -
Completed NCT NCT02049034
Lixisenatide-The Effects on Glucose and Lipid Metabolism in Type 2 Diabetes
Not yet reported University of Surrey 8 participants Est. completion 2016-01 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT02050074
The Role of Metformin and Colesevelam in Human GLP-1 Secretion
Not yet reported University Hospital, Gentofte, Copenhagen 12 participants Est. completion 2014-09 1 siteType 2 diabetesView official trial listing → -
Terminated NCT NCT02053103
A 6-Week Study To Determine The Safety And Effect Of An Investigational Drug On Adults With Type 2 Diabetes Mellitus Taking Metformin
Not yet reported Pfizer 13 participants Est. completion 2014-04 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT02058147
Efficacy and Safety of Insulin Glargine/ Lixisenatide Fixed Ratio Combination Compared to Insulin Glargine Alone and Lixisenatide Alone on Top of Metformin in Patients With T2DM
Not yet reported Sanofi 1170 participants Est. completion 2015-06 273 sitesType 2 diabetesView official trial listing → -
Terminated NCT NCT02072096
A Comparison of Two Treatment Strategies in Older Participants With Type 2 Diabetes Mellitus (T2DM)
Not yet reported Eli Lilly and Company 192 participants Est. completion 2015-10 34 sites Added to GLP-1Type 2 diabetesView official trial listing → -
Status unknown NCT NCT02072382
The Hypotensive Effect of Metformin in Hypertensive Patients.
Not yet reported Hospital de Clinicas de Porto Alegre 92 participants Est. completion 2015-12 1 site Stand-aloneOther conditions: HypertensionView official trial listing → -
Completed NCT NCT02076347
Comparison of Two Pharmacist-led Population Management Approaches to Increase Monitoring of Vitamin B12 and Serum Creatinine Levels for Patients on Metformin
Not yet reported Ohio State University 489 participants Est. completion 2015-10 1 siteType 2 diabetes Other conditions: Vitamin B12 Deficiency, Neuropathy, AnemiaView official trial listing → -
Completed NCT NCT02086526
Targeting Pathways in Polycystic Ovary Syndrome (PCOS) Using Metformin (MET)
Not yet reported Mayo Clinic 68 participants Est. completion 2016-11-20 1 site Stand-aloneOther conditions: Polycystic Ovary SyndromeView official trial listing → -
Active, not recruiting NCT NCT02087826
Study of Clinical Response to Acute Metformin By Leveraging Evaluations During a Mixed Meal Tolerance Test for Exploring Glycemia and GeneticS
Not yet reported Massachusetts General Hospital 1017 participants Est. completion 2026-12 1 siteType 2 diabetes Other conditions: Genetics, MetabolismView official trial listing → -
Completed NCT NCT02091362
A Study of LY2409021 on Blood Pressure and Pulse Rate in Participants With Type 2 Diabetes Mellitus
Not yet reported Eli Lilly and Company 270 participants Est. completion 2015-01 30 sites Stand-aloneType 2 diabetesView official trial listing → -
Status unknown NCT NCT02097342
Effect of Linagliptin on Insulin Sensitivity and Pancreatic Beta Cell Function in Patients With Type 2 Diabetes Mellitus
Not yet reported Post Graduate Institute of Medical Education and Research, Chandigarh 30 participants Est. completion 2015-01 1 siteType 2 diabetes Other conditions: Insulin Sensitivity/ResistanceView official trial listing → -
Completed NCT NCT02100475
A Trial Comparing Sequential Addition of Insulin Aspart Versus Further Dose Increase With Insulin Degludec/Liraglutide in Subjects With Type 2 Diabetes Mellitus, Previously Treated With Insulin Degludec/Liraglutide and Metformin and in Need of Further Intensification
Not yet reported Novo Nordisk A/S 31 participants Est. completion 2015-04 60 sites Added to GLP-1Type 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT02102932
Bioavailability of Empagliflozin/Metformin Fixed Dose Combinations (FDCs) in Healthy Chinese Volunteers
Not yet reported Boehringer Ingelheim 96 participants Est. completion 2014-08 1 siteOther conditions: HealthyView official trial listing → -
Completed NCT NCT02106923
Relative Bioavailability of 2 Fixed Dose Combinations of Empagliflozin/Metformin Extended Release (XR) Compared With Single Tablets
Not yet reported Boehringer Ingelheim 72 participants Est. completion 2014-07 1 siteOther conditions: HealthyView official trial listing → -
Terminated NCT NCT02115464
Advanced Lung Cancer Treatment With Metformin and Chemo-Radiotherapy
Not yet reported Ontario Clinical Oncology Group (OCOG) 54 participants Est. completion 2020-04-21 7 sites Stand-aloneOther conditions: Lung CancerView official trial listing → -
Completed NCT NCT02119819
A Study to Compare a New Drug for Type 2 Diabetes to Placebo and to a Treatment Already Available for Type 2 Diabetes
Not yet reported OPKO Health, Inc. 420 participants Est. completion 2015-10 51 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT02121509
Bioequivalence of a FDC Tablet of Linagliptin/Metformin (2.5mg/750mg) Extended Release in Healthy Subjects
Not yet reported Boehringer Ingelheim 74 participants Est. completion 2014-07 1 siteOther conditions: HealthyView official trial listing → -
Completed NCT NCT02125227
Phase 1 Clinical Trial to Investigate the Effect on the Pharmacokinetics of YH14755 Compared to Co-administration of Rosuvastatin and Metformin SR in Healthy Volunteers
Not yet reported Yuhan Corporation 56 participants Est. completion 2014-09 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Terminated NCT NCT02131272
A Trial Investigating the Efficacy and Safety of Insulin Detemir Versus Insulin NPH in Combination With Metformin and Diet/Exercise in Children and Adolescents With Type 2 Diabetes Insufficiently Controlled on Metformin With or Without Other Oral Antidiabetic Drug(s) With or Without Basal Insulin
Not yet reported Novo Nordisk A/S 42 participants Est. completion 2016-06-14 82 sitesType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT02133118
Weight Trajectory in New Users of Sulfonylureas as Add on Therapy Next to Metformin.
Medical Research Foundation, The Netherlands 16293 participants Est. completion 2014-12 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT02135549
Study of the Effectiveness and Safety of SugarDown vs. Placebo in Type 2 Diabetic Subjects Treated With Metformin
Not yet reported Boston Therapeutics 24 participants Est. completion 2014-10 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT02145611
Vildagliptin vs. Glibenclamide in Endothelial Function in Type 2 Diabetes and Hypertension
Not yet reported Dr. José Fernando Vilela-Martin MD PhD 50 participants Est. completion 2016-05 1 siteType 2 diabetes Other conditions: Hypertension, Endothelial DysfunctionView official trial listing → -
Completed NCT NCT02147925
Efficacy Study of Liraglutide vs.Sitagliptin vs. Glargine on Liver Fat in T2DM Subjects
Not yet reported Sun Yat-sen University 75 participants Est. completion 2017-04 1 siteOther conditions: Non-alcoholic Fatty Liver DiseaseView official trial listing → -
Completed NCT NCT02157974
Liver and Fat Regulation in Overweight Adolescent Girls
Not yet reported, Not yet reported University of Colorado, Denver 92 participants Est. completion 2022-12 1 siteOther conditions: Hepatic Steatosis, Polycystic Ovarian Syndrome, ObesityView official trial listing → -
Completed NCT NCT02160743
The Food Effect on Pharmacokinetics and Safety of Fixed-dose Combination of CJ-30056 in Healthy Male Subjects
Not yet reported HK inno.N Corporation 28 participants Est. completion 2014-11 1 site Stand-aloneOther conditions: Food Effect Study of CJ-30056 20mg/500mgView official trial listing → -
Completed NCT NCT02173639
Bioavailability of Combination Tablet BI 1356/Metformin Compared With Single BI 1356 and Metformin Administered Together to Healthy Male and Female Subjects
Not yet reported Boehringer Ingelheim 20 participantsOther conditions: HealthyView official trial listing → -
Completed NCT NCT02176161
Metformin Prostate Cancer Adjuvant Trial
Not yet reported NYU Langone Health 59 participants Est. completion 2021-07-21 1 site Stand-aloneOther conditions: Prostate Cancer, Prostate Cancer RecurrentView official trial listing → -
Completed NCT NCT02183571
Bioequivalence Study of Two Strengths of Two Different Metformin Tablets Administered to Healthy Male and Female Subjects
Not yet reported Boehringer Ingelheim 56 participantsOther conditions: HealthyView official trial listing → -
Completed NCT NCT02184832
Dietary Intake of Tryptophan and Metformin Response
Not yet reported Massachusetts General Hospital 20 participants Est. completion 2016-03 1 siteOther conditions: Metformin Response, Fasting Glucose, Tryptophan Concentration, Metformin Concentration, Diet TolerabilityView official trial listing → -
Completed NCT NCT02186847
Chemotherapy and Radiation Therapy With or Without Metformin Hydrochloride in Treating Patients With Stage III Non-small Cell Lung Cancer
Not yet reported NRG Oncology 170 participants Est. completion 2025-09-04 223 sites Stand-aloneOther conditions: Adenosquamous Lung Carcinoma, Bronchioloalveolar Carcinoma, Large Cell Lung Carcinoma, Lung Adenocarcinoma, Non-Small Cell Lung Carcinoma, Recurrent Non-Small Cell Lung Carcinoma, Squamous Cell Lung Carcinoma, Stage IIIA Non-Small Cell Lung Cancer, Stage IIIB Non-Small Cell Lung CancerView official trial listing → -
Completed NCT NCT02202161
A Study Investigating Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of GSK2330672 Administered With Metformin to Type 2 Diabetes Patients
Not yet reported GlaxoSmithKline 70 participants Est. completion 2015-01-30 4 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT02212756
Pharmacokinetic Profiles of Metformin With DW1029M
Not yet reported Dong Wha Pharmaceutical Co. Ltd. 12 participants Est. completion 2015-02 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Withdrawn NCT NCT02217670
Comparative Bioavailability Study of Metformin HCl 1000 mg Granules vs Glucophage 1000 mg Film-coated Tablet
Not yet reported Disphar International B.V. 1 site Stand-aloneOther conditions: Comparative BioavailabilityView official trial listing → -
Completed NCT NCT02220218
Bioequivalence Study of Metformin Component of Canagliflozin and Metformin Fixed Dose Combination Immediate Release (IR) Tablet Comparing With Metformin IR Tablet Co-administered With Canagliflozin Tablet in Healthy Fed and Fasted Participants
Not yet reported Janssen Research & Development, LLC 2 participants Est. completion 2014-10 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT02220647
Bioequivalence of a 2.5 mg Linagliptin / 850 mg Metformin Fixed Dose Combination Tablet Compared With Single Linagliptin 2.5 mg and Metformin 850 mg Tablets in Healthy Volunteers
Not yet reported Boehringer Ingelheim 96 participants Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT02221401
Bioequivalence of a Linagliptin / Metformin Fixed-dose Combination (FDC) Tablet Compared With Single Linagliptin and Metformin Tablets Administered Together in Healthy Volunteers
Not yet reported Boehringer Ingelheim 96 participants Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT02221414
Bioequivalence of a 2.5 mg Linagliptin / 500 mg Metformin Fixed Dose Combination Tablet Compared With Single Linagliptin 2.5 mg and Metformin 500 mg Tablets Administered Together in Healthy Volunteers
Not yet reported Boehringer Ingelheim 95 participantsOther conditions: HealthyView official trial listing → -
Completed NCT NCT02223026
Relative Bioavailability of a Linagliptin+Metformin Fixed Dose Combination Tablet Administered With and Without Food to Healthy Male and Female Subjects
Not yet reported Boehringer Ingelheim 32 participantsOther conditions: HealthyView official trial listing → -
Completed NCT NCT02226510
MetfoRmin and Its Effects on Left Ventricular Hypertrophy in Normotensive Patients With Coronary Artery Disease
Not yet reported University of Dundee 68 participants Est. completion 2017-12 1 siteCardiovascular diseasePrediabetes Other conditions: Left Ventricular Hypertrophy, Insulin ResistanceView official trial listing → -
Withdrawn NCT NCT02229240
Albiglutide Versus Placebo Added-on to Basal-Bolus Insulin Therapy in Subjects With Type 2 Diabetes Mellitus
Not yet reported GlaxoSmithKline Est. completion 2015-12Type 2 diabetesView official trial listing → -
Terminated NCT NCT02244164
Pathophysiological Study of the Increase in Pancreatic Volume in Type 2 Diabetes Treatments.
Not yet reported Erasme University Hospital 5 participants Est. completion 2023-02-13 1 siteType 2 diabetes Other conditions: Incretinomimetics, PancreasView official trial listing → -
Status unknown NCT NCT02244567
Effect of Metformin Therapy on Serum Under-carboxylated Osteocalcin Levels in Hyperandrogenic Lean Polycystic Ovarian Syndrome Women
Not yet reported Beni-Suef University 100 participants Est. completion 2021-06 1 siteOther conditions: Polycystic Ovarian SyndromeView official trial listing → -
Completed NCT NCT02249910
Investigating the Influence of Oral Semaglutide on Pharmacokinetics of Metformin and Digoxin in Healthy Subjects
Not yet reported Novo Nordisk A/S 32 participants Est. completion 2015-03-06 1 site Added to GLP-1Other conditions: Diabetes, HealthyView official trial listing → -
Completed NCT NCT02252965
Metformin Extended Release Versus Metformin Immediate Release in Subjects With Type 2 Diabetes
Not yet reported Merck KGaA, Darmstadt, Germany 532 participants Est. completion 2016-04 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT02266472
Bioequivalence of a Fixed Dose Combination Tablet of Empagliflozin/Metformin Extended Release Compared With Mono Compound Tablets in Healthy Male and Female
Not yet reported Boehringer Ingelheim 30 participants Est. completion 2014-12 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Status unknown NCT NCT02275845
Medico-GDM Trial - Metformine to Prevent Gestational Diabetes Mellitus
Not yet reported Maasstad Hospital 400 participants Est. completion 2017-09 1 siteOther conditions: Gestational Diabetes MellitusView official trial listing → -
Status unknown NCT NCT02279758
A Pilot Study of Metformin Treatment in Patients With Well-differentiated Neuroendocrine Tumors
Not yet reported Instituto do Cancer do Estado de São Paulo 30 participants 1 siteOther conditions: Well-differentiated Neuroendocrine TumorsView official trial listing → -
Completed NCT NCT02283554
Platelet Rich Fibrin With 1% Metformin Gel for Treatment of Intrabony Defects
Not yet reported Government Dental College and Research Institute, Bangalore 120 participantsOther conditions: PeriodontitisView official trial listing → -
Completed NCT NCT02288273
Study to Evaluate the Effect of BYDUREON on 24-hour Glucose Control in Metformin Treated Patients With Type 2 Diabetes.
Not yet reported AstraZeneca 239 participants Est. completion 2015-08 29 sitesType 2 diabetesView official trial listing → -
Status unknown NCT NCT02294006
Activity and Safety of Everolimus+Octreotide LAR+Metformin in Advanced Pancreatic Well-differentiated NETs
Not yet reported Fondazione IRCCS Istituto Nazionale dei Tumori, Milano 26 participants Est. completion 2021-10 1 site Stand-aloneOther conditions: Well Differentiated Pancreatic Endocrine TumorView official trial listing → -
Completed NCT NCT02298192
A Clinical Trial Comparing Efficacy and Safety of Insulin Degludec/Liraglutide (IDegLira) in Subjects With Type 2 Diabetes Mellitus Using Two Different Titration Algorithms
Not yet reported Novo Nordisk A/S 420 participants Est. completion 2015-12-23 84 sitesType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT02304081
Saxagliptin in Combination With Dapagliflozin - Effects on Islet Cell Function
Not yet reported Prof. Dr. Thomas Forst 64 participants Est. completion 2016-08 1 siteType 2 diabetesView official trial listing → -
Active, not recruiting NCT NCT02336087
Gemcitabine Hydrochloride, Paclitaxel Albumin-Stabilized Nanoparticle Formulation, Metformin Hydrochloride, and a Standardized Dietary Supplement in Treating Patients With Pancreatic Cancer That Cannot be Removed by Surgery
Not yet reported City of Hope Medical Center 21 participants Est. completion 2026-12-09 4 sitesOther conditions: Pancreatic Adenocarcinoma, Unresectable Pancreatic Carcinoma, Stage III Pancreatic Cancer AJCC v6 and v7, Stage IV Pancreatic Cancer AJCC v6 and v7View official trial listing → -
Completed NCT NCT02338921
Triple Combination Therapy in Type 2 Diabetic Patients Who Had Inadequate Glycemic Control With Combination Therapy
Not yet reported Seoul National University Bundang Hospital 78 participants Est. completion 2021-12-31 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT02339168
Enzalutamide and Metformin Hydrochloride in Treating Patients With Hormone-Resistant Prostate Cancer
Not yet reported University of California, Davis 25 participants Est. completion 2025-02-24 1 site Stand-aloneOther conditions: Prostate CancerView official trial listing → -
Completed NCT NCT02341703
Ovulation Induction in Clomiphene Citrate Resistant PCO Women
Not yet reported Cairo University 100 participants Est. completion 2015-07 1 siteOther conditions: Polycystic Ovary Syndrome, InfertilityView official trial listing → -
Completed NCT NCT02367066
A Phase I Study to Assess the Pharmacodynamics of Oral AR-C165395XX in Subjects With Type 2 Diabetes Mellitus (T2DM)
Not yet reported AstraZeneca 30 participants Est. completion 2015-05 1 siteType 2 diabetesView official trial listing → -
Status unknown NCT NCT02368704
Role of Endoplasmic Reticulum Stress in the Pathophysiology of Type 2 Diabetes
Assistance Publique - Hôpitaux de Paris 40 participants Est. completion 2016-11 1 siteType 2 diabetes Other conditions: Endoplasmic Reticulum StressView official trial listing → -
Completed NCT NCT02372656
Simvastatin and Metformin in Chronic Periodontitis
Not yet reported, Not yet reported Government Dental College and Research Institute, Bangalore 98 participants Est. completion 2014-08Other conditions: Chronic PeriodontitisView official trial listing → -
Status unknown NCT NCT02383563
Metformin for HIV Inflammation
Not yet reported University of Hawaii 12 participants Est. completion 2016-02 1 siteCardiovascular disease Other conditions: HIVView official trial listing → -
Status unknown NCT NCT02394158
Preventing Recurrent Gestational Diabetes With Metformin
Not yet reported Imperial College London 112 participants Est. completion 2019-09-30 2 sitesOther conditions: Gestational Diabetes MellitusView official trial listing → -
Completed NCT NCT02394652
The Potential for Metformin to Improve Tumor Oxygenation in Locally Advanced Cervix Cancer: A Phase II Randomized Trial
Not yet reported University Health Network, Toronto 16 participants Est. completion 2021-01-12 5 sites Stand-aloneOther conditions: Uterine Cervical Neoplasms, Squamous Cell Carcinoma, Adenocarcinoma, Carcinoma, AdenosquamousView official trial listing → -
Completed NCT NCT02401880
Effects of Linagliptin in Addition to Empagliflozin on Islet Cell Physiology
Not yet reported Profil Institut für Stoffwechselforschung GmbH 89 participants Est. completion 2015-12 2 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT02405260
Add Glucokinase Activator to Target A1c
Not yet reported vTv Therapeutics 190 participants Est. completion 2016-09 20 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT02407899
Protective Effects of Saxagliptin (And Vitamin D3) on β Cell Function in Adult-onset Latent Autoimmune Diabetes
Not yet reported Second Xiangya Hospital of Central South University 300 participants Est. completion 2020-12-31 39 sites Stand-aloneOther conditions: Diabetes Mellitus, Type 1View official trial listing → -
Completed NCT NCT02411825
Multiple Ascending Dose Study in Healthy Male Subjects and Overweight to Obese Male and Female Type 2 Diabetes Mellitus (T2DM) Patients
Not yet reported Sanofi 76 participants Est. completion 2016-01 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT02417090
Late Metabolic Effects of Metformin Therapy in Gestational Diabetes
Turku University Hospital 173 participants Est. completion 2019-12-01Other conditions: Gestational DiabetesView official trial listing → -
Completed NCT NCT02420262
A Clinical Trial Comparing Efficacy and Safety of Insulin Degludec/Liraglutide (IDegLira) Versus Basal-bolus Therapy in Subjects With Type 2 Diabetes Mellitus
Not yet reported Novo Nordisk A/S 506 participants Est. completion 2016-10-05 117 sites Added to GLP-1Type 2 diabetes Other conditions: DiabetesView official trial listing → -
Status unknown NCT NCT02426294
Comparison of Pioglitazone Versus Glimepiride in Type 2 Diabetes Inadequately Controlled With Metformin Plus Alogliptin
Not yet reported Pusan National University Hospital 154 participants Est. completion 2016-05 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT02431676
Survivorship Promotion In Reducing IGF-1 Trial
Not yet reported Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 121 participants Est. completion 2018-12 1 site Stand-aloneOther conditions: Breast Cancer, Prostate Cancer, Lung Cancer, Colon Cancer, Melanoma of Skin, Endometrial Cancer, Liver Cancer, Pancreatic Cancer, Rectal Cancer, Kidney Cancer, Other Solid Malignant TumorsView official trial listing → -
Completed NCT NCT02437656
Combination of Metformin to Neoadjuvant Radiochemotherapy in the Treatment of Locally Advanced Rectal Cancer.
Not yet reported Centre Oscar Lambret 60 participants Est. completion 2017-03 11 sitesOther conditions: Rectal CancerView official trial listing → -
Completed NCT NCT02440893
Understanding the Effect of Metformin on Corus CAD (or ASGES)
CardioDx 37 participants Est. completion 2014-06Cardiovascular disease Other conditions: Angina Pectoris, Chest Pain, Coronary Heart Disease, CAD, CVD, CHDView official trial listing → -
Completed NCT NCT02471404
Efficacy and Safety of Dapagliflozin and Dapagliflozin Plus Saxagliptin in Combination With Metformin in Type 2 Diabetes Patients Compared With Sulphonylurea
Not yet reported AstraZeneca 939 participants Est. completion 2017-03-13 173 sitesType 2 diabetes Other conditions: Inadequate Glycaemic ControlView official trial listing → -
Terminated NCT NCT02473094
Neoadjuvant Metformin in Association to Chemoradiotherapy for Locally Advanced Rectal Cancer
Not yet reported University of Campinas, Brazil 3 participants Est. completion 2016-02 1 site Stand-aloneOther conditions: Rectal Neoplasms, Adenocarcinoma, CarcinomaView official trial listing → -
Status unknown NCT NCT02480465
Efficacy and Safety of Lobeglitazone Versus Sitagliptin
Not yet reported Chong Kun Dang Pharmaceutical 248 participants Est. completion 2017-03 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT02488564
A Study of Liposomal Doxorubicin+Docetaxel+Trastuzumab+Metformin in Operable and Locally Advanced HER2 Positive Breast Cancer
Not yet reported Istituto Romagnolo per lo Studio dei Tumori Dino Amadori IRST S.r.l. IRCCS 49 participants Est. completion 2020-03-17 9 sitesOther conditions: HER-2 Positive Breast CancerView official trial listing → -
Completed NCT NCT02496000
Phase II Safety and Efficacy Study of Oral ORMD-0801 in Patients With Type 2 Diabetes Mellitus
Not yet reported Oramed, Ltd. 188 participants Est. completion 2016-09-13 34 sitesOther conditions: Diabetes Type 2View official trial listing → -
Completed NCT NCT02496741
Metformin And Chloroquine in IDH1/2-mutated Solid Tumors
Not yet reported, Not yet reported Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) 15 participants Est. completion 2019-11-18 3 sitesObstructive sleep apnea Other conditions: Glioma, CholangiocarcinomaView official trial listing → -
Completed NCT NCT02497313
Effect of Metformin and Cholecystokinin-mediated Gallbladder Emptying on GLP-1 Secretion in Type 2 Diabetes
Not yet reported University Hospital, Gentofte, Copenhagen 15 participants Est. completion 2016-07 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT02500628
Heart Rate Variability in Response to Metformin Challenge
Not yet reported Woodinville Psychiatric Associates 61 participants Est. completion 2016-02 1 site Stand-aloneType 2 diabetes Other conditions: Fibromyalgia, Mitochondrial Diseases, Movement DisordersView official trial listing → -
Status unknown NCT NCT02502344
Effect of Medical Interventions in Insulin Resistance on Prevalence of Abnormal Glucose Tolerance
Not yet reported Beijing Tsinghua Chang Gung Hospital 60 participants 1 siteOther conditions: Insulin ResistanceView official trial listing → -
Completed NCT NCT02514629
Testosterone, Metformin, or Both, for Hypogonadism in Obese Males
Not yet reported Fundación Pública Andaluza para la Investigación de Málaga en Biomedicina y Salud 107 participants Est. completion 2016-07-12 1 site Stand-aloneOther conditions: Hypogonadism, ObesityView official trial listing → -
Completed NCT NCT02524821
The Effect of Gelesis100 on the Pharmacokinetics of Metformin
Not yet reported Gelesis, Inc. 24 participants Est. completion 2015-12 1 siteOther conditions: Healthy Overweight ObeseView official trial listing → -
Completed NCT NCT02526524
Dose-Ranging Study to Evaluate the Glycemic Effects, Safety, and Tolerability of Metformin Delayed Release in Subjects With T2DM
Not yet reported Elcelyx Therapeutics, Inc. 571 participants Est. completion 2016-09 137 sitesType 2 diabetesView official trial listing → -
Status unknown NCT NCT02535299
Par-4 and Telomere-telomerase System in Type 2 Diabetes Patients Who Received GLP-1 or Metformin Treatment
Not yet reported Third Military Medical University 200 participants Est. completion 2019-12 1 siteOther conditions: GLP-1;Metformin;Telomere-telomerase System;Par-4View official trial listing → -
Status unknown NCT NCT02535975
The Effects of Metformin in Patients With Mild Graves' Ophthalmopathy
Not yet reported Yonsei University 80 participants Est. completion 2019-10 1 siteOther conditions: Mild Graves' OphthalmopathyView official trial listing → -
Completed NCT NCT02551874
A 24-week Open-Label, Phase 3b Trial With a 28-week Extension to Evaluate the Efficacy and Safety of Saxagliptin Co-administered With Dapagliflozin Compared to Insulin Glargine in Subjects withType 2 Diabetes Who Have Glycemic Control on Metformin
Not yet reported AstraZeneca 650 participants Est. completion 2017-11-10 40 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT02570672
Metformin for Preventing Frailty in High-risk Older Adults
Not yet reported The University of Texas Health Science Center at San Antonio 141 participants Est. completion 2024-02-07 1 siteOther conditions: FrailtyView official trial listing → -
Completed NCT NCT02580331
1% Metformin Gel in the Treatment of Class II Furcation Defects
Not yet reported, Not yet reported Government Dental College and Research Institute, Bangalore 64 participants Est. completion 2015-09 1 siteOther conditions: Chronic PeriodontitisView official trial listing → -
Completed NCT NCT02586129
Clinical Trial of YH14755 in Subjects With Dyslipidemia and Type II Diabetes
Not yet reported Yuhan Corporation 249 participants Est. completion 2017-07-07 1 siteOther conditions: Dyslipidemia, Type II DiabetesView official trial listing → -
Completed NCT NCT02586636
Impact of OCT1 on Metformin Tolerance
Not yet reported NHS Tayside 61 participants Est. completion 2018-04-09 1 siteOther conditions: ToleranceView official trial listing → -
Status unknown NCT NCT02587741
Comparison of Diabetes Retinopathy Among Type 2 Diabetic Patients Treated With Different Regimens
Not yet reported Third Affiliated Hospital, Sun Yat-Sen University 600 participants Est. completion 2025-07 1 site Stand-aloneOther conditions: Diabetic RetinopathyView official trial listing → -
Completed NCT NCT02588859
Study to Understand Usage and Effect of Saxagliptin as First Add-On After Metformin in Indian Type 2 Diabetes Mellitus Patients
AstraZeneca 1200 participants Est. completion 2016-12-26 31 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT02597101
Anti-Inflammatory Small Drug Adjunctive Therapy for Type 2 Diabetes
Not yet reported Nick Giannoukakis, PhD 14 participants Est. completion 2019-06-15 1 site Stand-aloneType 2 diabetes Other conditions: Insulin ResistanceView official trial listing → -
Completed NCT NCT02607410
Sitagliptin (DPP-4 Inhibitor) and NPH Insulin in Patients With T2D
Not yet reported University of Sao Paulo General Hospital 40 participants Est. completion 2014-07 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT02627898
Effect of Green Tea Extract on Arterial Stiffness in Type 2 Diabetes Mellitus
Not yet reported Centro Universitario de Ciencias de la Salud, Mexico 24 participants Est. completion 2016-12Type 2 diabetesView official trial listing → -
Completed NCT NCT02629627
Conjugated Linoleic Acid / Leucine Versus Metformin on Visceral Fat in Metabolic Syndrome
Not yet reported Centro Universitario de Ciencias de la Salud, Mexico 104 participants Est. completion 2017-10 Stand-aloneMetabolic syndromeView official trial listing → -
Completed NCT NCT02630706
A Study to Evaluate the Efficacy and Safety of Ertugliflozin in Asian Participants With Type 2 Diabetes and Inadequate Glycemic Control on Metformin Monotherapy (MK-8835-012)
Not yet reported Merck Sharp & Dohme LLC 506 participants Est. completion 2017-12-27Type 2 diabetesView official trial listing → -
Completed NCT NCT02638805
Study of the Safety and Tolerability of Switching to ITCA 650 in Patients With Type 2 Diabetes Receiving Liraglutide
Not yet reported Intarcia Therapeutics 136 participants Est. completion 2017-10 36 sites Added to GLP-1Type 2 diabetesView official trial listing → -
Status unknown NCT NCT02670018
BE Study of the Combinations of Gemigliptin 50mg and Metformin HCl Extended Release 2000mg in Comparison to Each Component Administered Alone
Not yet reported LG Life Sciences 25 participants Est. completion 2016-03 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Status unknown NCT NCT02672488
Metformin Plus Sorafenib for Advanced HCC
Not yet reported Tianjin Medical University Cancer Institute and Hospital 82 participants Est. completion 2018-12 1 siteOther conditions: Hepatocellular CarcinomaView official trial listing → -
Completed NCT NCT02693392
Clinical Evaluation of Fenugreek Seed Extract, a Nutraceutical in Patients With Type- 2 Diabetes
Not yet reported All India Institute of Medical Sciences, Bhubaneswar 200 participants Est. completion 2018-08-16 1 site Stand-aloneOther conditions: Type-2 Diabetes MellitusView official trial listing → -
Withdrawn NCT NCT02694289
Effects of Metformin in Heart Failure Patients
Not yet reported Maya Guglin Est. completion 2018-09-10Type 2 diabetesView official trial listing → -
Withdrawn NCT NCT02719132
Effect of DapagliFLOzin on Quality of Life in Patients With Type 2 Diabetes in a Real Clinical PrActice
Not yet reported AstraZeneca Est. completion 2017-11Type 2 diabetesView official trial listing → -
Completed NCT NCT02738879
Randomized Sitagliptin Withdrawal Study (MK-0431-845)
Not yet reported Merck Sharp & Dohme LLC 746 participants Est. completion 2018-01-30Type 2 diabetesView official trial listing → -
Completed NCT NCT02741960
The Effect of Metformin on Reducing Lupus Flares
Not yet reported RenJi Hospital 180 participants Est. completion 2018-12-07 1 siteOther conditions: Systemic Lupus ErythematosusView official trial listing → -
Completed NCT NCT02751307
Adjunctive Low-dose Metformin in Patients With Schizophrenia and Metabolic Abnormalities
Not yet reported Taipei Medical University WanFang Hospital 55 participants Est. completion 2015-01Metabolic syndromeView official trial listing → -
Completed NCT NCT02752113
Effects of Empagliflozin + Linagliptin vs Metformin + Insulin Glargine on Renal and Vascular Changes in Type 2 Diabetes
Not yet reported Institut für Pharmakologie und Präventive Medizin 101 participants Est. completion 2019-05 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT02752412
Efficacy and Safety of LixiLan Versus Insulin Glargine Alone Both With Metformin in Japanese With Type 2 Diabetes Mellitus Inadequately Controlled on Basal Insulin and Oral Antidiabetic Drugs
Not yet reported Sanofi 513 participants Est. completion 2018-10-04 122 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT02760342
A Drug Interaction Study to Evaluate the Pharmacokinetics of ASP015K and Metformin
Not yet reported Astellas Pharma Inc 24 participants Est. completion 2016-06-26 1 site Stand-aloneOther conditions: Healthy SubjectsView official trial listing → -
Completed NCT NCT02765347
The Effects of Metformin on Glycemic Control and Insulin Sensitivity in Adolescents With T1DM
Not yet reported Third Affiliated Hospital, Sun Yat-Sen University 30 participants Est. completion 2018-01 1 siteOther conditions: Diabetes Mellitus, Type 1View official trial listing → -
Completed NCT NCT02773927
Combination of Metformin/Inulin vs Inulin on Adiponectin in Metabolic Syndrome
Not yet reported Centro Universitario de Ciencias de la Salud, Mexico 40 participants Est. completion 2015-06 1 site Stand-aloneMetabolic syndromeView official trial listing → -
Completed NCT NCT02778776
Combination of Metformine/Inulin Versus Metformin on Prostate Benign Hyperplasia in Metabolic Syndrome
Not yet reported Centro Universitario de Ciencias de la Salud, Mexico 40 participants Est. completion 2015-06 1 site Stand-aloneMetabolic syndromeView official trial listing → -
Completed NCT NCT02786823
Effect of Folic Acid and Vitamin B12 Supplementation in Subjects With Type 2 Diabetes
Not yet reported, Not yet reported All India Institute of Medical Sciences, Bhubaneswar 80 participants Est. completion 2017-09-15 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT02793505
Safety of Metformin in Pregnancy
Centre Hospitalier Universitaire Vaudois 950 participantsOther conditions: Pregnancy, Pregestational Diabetes, Polycystic Ovary SyndromView official trial listing → -
Completed NCT NCT02794792
A Study to Assess the Efficacy and Safety of Ipragliflozin in Subjects With Type 2 Diabetes Mellitus Who Have Inadequate Glycemic Control on Metformin
Not yet reported Astellas Pharma Europe B.V. 268 participants Est. completion 2017-06-20 14 sites Stand-aloneType 2 diabetesView official trial listing → -
Status unknown NCT NCT02802215
Metformin for Prevention Gestational Diabetes in Pregnant Women With Polycystic Ovarian Syndrome
Not yet reported, Not yet reported Ain Shams University 80 participants Est. completion 2016-09 1 siteOther conditions: Polycystic Ovary Syndrome, Diabetes, GestationalView official trial listing → -
Completed NCT NCT02803918
A Study on Safety, Pharmacokinetics and Pharmacodynamics of Lixisenatide in Pediatric Patients With Type 2 Diabetes Mellitus (T2DM)
Not yet reported Sanofi 23 participants Est. completion 2020-01-27 11 sites Added to GLP-1Type 2 diabetesView official trial listing → -
Completed NCT NCT02813863
The Drug-drug Interaction of SP2086 and Metformin
Not yet reported Jiangsu HengRui Medicine Co., Ltd. 24 participantsType 2 diabetesView official trial listing → -
Completed NCT NCT02821910
Relative Bioavailability of 2 Fixed Dose Combinations of Empagliflozin/Linagliptin/Metformin Extended Release Compared With Single Tablets
Not yet reported Boehringer Ingelheim 50 participants Est. completion 2016-10-31 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Status unknown NCT NCT02823691
The MetNET-2 Trial
Not yet reported Fondazione IRCCS Istituto Nazionale dei Tumori, Milano 20 participants Est. completion 2021-12 1 site Stand-aloneOther conditions: Neuroendocrine TumorsView official trial listing → -
Status unknown NCT NCT02823808
Effect of Alogliptin/Pioglitazone on the Preservation of Long-term Beta-cell Function
Not yet reported Kyunghee University Medical Center 96 participants Est. completion 2021-12 1 siteOther conditions: DiabetesView official trial listing → -
Completed NCT NCT02831361
Trial to Evaluate the Efficacy and Safety of Gemigliptin Compared With Placebo Added on Insulin Alone or on Insulin in Combination With Metformin in Type 2 DM (ZEUS II Study)
Not yet reported LG Life Sciences 290 participants Est. completion 2018-02-08 Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT02853630
A Clinical Trial to Study the Effects of Two Drugs, Vildagliptin and Metformin in Patients With Type 2 Diabetes Mellitus
Not yet reported India Diabetes Research Foundation & Dr. A. Ramachandran's Diabetes Hospitals 203 participants Est. completion 2018-12 6 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT02865668
A Study to Assess the Bioequivalence of the Metformin Component of the Fixed Dose Combination Tablet of Canagliflozin and Metformin Extended Release With Respect to Metformin XR Tablet Coadministered With Canagliflozin in Healthy Fed and Fasted Participants
Not yet reported Janssen Research & Development, LLC 44 participants Est. completion 2016-10 1 siteOther conditions: HealthyView official trial listing → -
Terminated NCT NCT02874430
Metformin Hydrochloride and Doxycycline in Treating Patients With Localized Breast or Uterine Cancer
Not yet reported Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University 29 participants Est. completion 2020-12-11 1 siteObstructive sleep apnea Other conditions: Breast Carcinoma, Endometrial Clear Cell Adenocarcinoma, Endometrial Serous Adenocarcinoma, Uterine Corpus CancerView official trial listing → -
Completed NCT NCT02875821
Effects of Ipragliflozin on Excessive Fat in Type 2 Diabetes Patients With Non-alcoholic Fatty Liver Disease Treated With Metformin and Pioglitazone
Not yet reported Yonsei University 44 participants Est. completion 2017-06-07 1 siteMASLDType 2 diabetesView official trial listing → -
Active, not recruiting NCT NCT02879409
HbA1c Variability in Type II Diabetes
Not yet reported Weill Cornell Medical College in Qatar 150 participants Est. completion 2026-10-01 1 site Added to GLP-1Type 2 diabetesView official trial listing → -
Status unknown NCT NCT02882477
Treatment of Wolfram Syndrome Type 2 With the Chelator Deferiprone and Incretin Based Therapy
Not yet reported, Not yet reported Hadassah Medical Organization 20 participants Est. completion 2018-12 1 siteOther conditions: Diabetes Mellitus, Iron Metabolism Disorders, Gastroduodenal Ulcer, Optic Atrophy, Sensorineural Hearing Loss, Platelet DysfunctionView official trial listing → -
Completed NCT NCT02884089
A Study of the Effect of Abemaciclib on Metformin and Iohexol in Healthy Participants
Not yet reported Eli Lilly and Company 40 participants Est. completion 2016-12 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Status unknown NCT NCT02887625
Exenatide Plus Pioglitazone Versus Insulin in Poorly Controlled T2DM
Not yet reported Dr. Muhammad Abdulghani 410 participants Est. completion 2017-05 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT02895750
Efficacity and Safety of Metformin XR in CKD Stage 1 to 3
Not yet reported Centre Hospitalier Universitaire, Amiens 12 participants Est. completion 2022-10-10 1 site Stand-aloneOther conditions: Renal Insufficiency, ChronicView official trial listing → -
Completed NCT NCT02909933
Low Dose Liraglutide and Metformin vs. High Dose Liraglutide Alone in Treatment of Obesity
Not yet reported University Medical Centre Ljubljana 30 participants Est. completion 2015-10 1 site Added to GLP-1Other conditions: Polycystic Ovary Syndrome, ObesityView official trial listing → -
Completed NCT NCT02911792
Effect of Farxiga on Renal Function and Size in Type 2 Diabetic Patients With Hyperfiltration
Not yet reported The University of Texas Health Science Center at San Antonio 72 participants Est. completion 2023-07-11 2 sitesType 2 diabetesView official trial listing → -
Terminated NCT NCT02932475
Medical Optimization of Management of Type 2 Diabetes Complicating Pregnancy (MOMPOD)
Not yet reported University of North Carolina, Chapel Hill 831 participants Est. completion 2022-06-15 10 sitesOther conditions: Diabetes, PregnancyView official trial listing → -
Completed NCT NCT02941445
Weight Maintenance With Dipeptidyl Peptidase 4 (DPP4) Inhibitor Sitagliptin in Combination With Metformin After Liragludite Induced Weight Loss
Not yet reported University Medical Centre Ljubljana 24 participants Est. completion 2016-08 Stand-aloneOther conditions: Polycystic Ovary Syndrome, Body WeightView official trial listing → -
Terminated NCT NCT02945813
SAKK 08/15 - PROMET - Salvage Radiotherapy +/- Metformin for Patients With Prostate Cancer After Prostatectomy
Not yet reported Swiss Cancer Institute 112 participants Est. completion 2022-02-28 27 sites Stand-aloneOther conditions: Prostate CancerView official trial listing → -
Completed NCT NCT02947620
Metformin/Atorvastatin Combination Therapy in Subjects With Type II Diabetes and Dyslipidemia (Phase 3)
Not yet reported Daewoong Pharmaceutical Co. LTD. 185 participants Est. completion 2017-02-27 1 siteOther conditions: Type II Diabetes, DyslipidemiaView official trial listing → -
Completed NCT NCT02954692
A Study to Evaluate the Effectiveness and Safety Initiation and Titration of Insulin Glargine (U300) in Insulin-naïve Patients With Type 2 Diabetes Mellitus (T2DM) Controlled on Oral Antidiabetic Drug Treatment in Turkey
Not yet reported Sanofi 112 participants Est. completion 2017-12-22 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT02964247
LIRA-ADD2SGLT2i - Liraglutide Versus Placebo as add-on to SGLT2 Inhibitors.
Not yet reported Novo Nordisk A/S 303 participants Est. completion 2018-05-08 82 sitesType 2 diabetes Other conditions: DiabetesView official trial listing → -
Terminated NCT NCT02967276
Clinical Activity of Metformin With High-dose of Dexamethasone in Relapse Multiple Myeloma
Not yet reported University of Campinas, Brazil 28 participants Est. completion 2020-02 2 sites Stand-aloneOther conditions: Multiple MyelomaView official trial listing → -
Completed NCT NCT02980276
RCT Metformin for Reduction of Gestational Diabetes Mellitus Effects
Not yet reported National University of Ireland, Galway, Ireland 535 participants Est. completion 2023-04-13 2 sitesOther conditions: Gestational DiabetesView official trial listing → -
Completed NCT NCT02981329
Fetal Hemoglobin Induction Treatment Metformin
Not yet reported Baylor College of Medicine 37 participants Est. completion 2020-07-20 2 sitesOther conditions: Sickle Cell Anemia, Sickle Cell Disease, Hemoglobin DisorderView official trial listing → -
Completed NCT NCT02986659
Genomic Outcomes of Metformin
Not yet reported Wake Forest University Health Sciences 30 participants Est. completion 2018-11-15 1 siteCardiovascular disease Other conditions: Mild Cognitive Impairment, Obesity, Abdominal, HypertensionView official trial listing → -
Completed NCT NCT03017833
Sapanisertib and Metformin in Treating Patients With Advanced or Metastatic Relapsed or Refractory Cancers
Not yet reported M.D. Anderson Cancer Center 31 participants Est. completion 2022-12-21 1 site Stand-aloneOther conditions: Advanced Malignant Solid Neoplasm, Metastatic Malignant Solid Neoplasm, Recurrent Malignant Solid Neoplasm, Refractory NeoplasmView official trial listing → -
Status unknown NCT NCT03029390
Effect of Berberine Versus Metformin on Glycemic Control, Insulin Sensitivity and Insulin Secretion in Prediabetes
Not yet reported University of Guadalajara 28 participants Est. completion 2023-12 1 sitePrediabetesView official trial listing → -
Completed NCT NCT03029702
Metabolic Analysis for Treatment Choice in Gestational Diabetes Mellitus
Not yet reported Maisa N. Feghali, MD 54 participants Est. completion 2023-08-31 1 siteOther conditions: Gestational Diabetes, Diabetes, Gestational, Pregnancy in DiabetesView official trial listing → -
Completed NCT NCT03030300
Remission Rate of Newly Diagnosed Type 2 Diabetes Outpatients Treated With Short-term Intensive Insulin Therapy
Not yet reported Qianfoshan Hospital 170 participants Est. completion 2015-02 3 sitesType 2 diabetesView official trial listing → -
Terminated NCT NCT03031821
Metformin in Patients Initiating ADT as Prevention and Intervention of Metabolic Syndrome
Not yet reported Canadian Urologic Oncology Group 166 participants Est. completion 2023-11-24 16 sites Stand-aloneMetabolic syndrome Other conditions: Prostate CancerView official trial listing → -
Completed NCT NCT03041129
Post-Prandial Liver Glucose Metabolism in PCOS
University of Colorado, Denver 19 participants Est. completion 2018-09-29 1 siteOther conditions: Polycystic Ovarian Syndrome, Obesity, Hepatic SteatosisView official trial listing → -
Status unknown NCT NCT03048500
Nivolumab and Metformin Hydrochloride in Treating Patients With Stage III-IV Non-small Cell Lung Cancer That Cannot Be Removed by Surgery
Not yet reported Northwestern University 17 participants Est. completion 2021-09 2 sitesOther conditions: Recurrent Non-Small Cell Lung Carcinoma, Stage III Non-Small Cell Lung Cancer, Stage IIIA Non-Small Cell Lung Cancer, Stage IIIB Non-Small Cell Lung Cancer, Stage IV Non-Small Cell Lung CancerView official trial listing → -
Completed NCT NCT03049228
In and ex Vivo Mitochondrial Function of the Heart
Maastricht University Medical Center 38 participants Est. completion 2020-03-02 1 siteType 2 diabetes Other conditions: Diabetic CardiomyopathiesView official trial listing → -
Suspended NCT NCT03051451
Fixed Dose Combination of Fluoxetin and Metformin in the Management of Overweight and Obesity
Not yet reported Laboratorios Silanes S.A. de C.V. 150 participants Est. completion 2018-11 1 siteOther conditions: Overweight and ObesityView official trial listing → -
Completed NCT NCT03061214
Efficacy and Safety of Semaglutide Once-weekly Versus Sitagliptin Once-daily as add-on to Metformin in Subjects With Type 2 Diabetes (SUSTAIN - CHINA MRCT)
Not yet reported Novo Nordisk A/S 868 participants Est. completion 2019-04-15 67 sitesType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT03088670
Efficacy and Safety of Gosogliptin as Monotherapy and in Combination With Metformin vs. Vildagliptin as Monotherapy and in Combination With Metformin in Drug-naive Type 2 Diabetic Patients.
Not yet reported SatRx LLC 299 participants Est. completion 2014-10-03 27 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT03108963
L-carnitine and Metformin in Obese PCOS Women.
Not yet reported Zagazig University 280 participants Est. completion 2018-03 1 siteOther conditions: PCOSView official trial listing → -
Completed NCT NCT03109873
Metformin Hydrochloride in Affecting Cytokines and Exosomes in Patients With Head and Neck Cancer
Not yet reported Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University 9 participants Est. completion 2020-07-31 1 site Stand-aloneOther conditions: Larynx, Lip, Oral Cavity, PharynxView official trial listing → -
Completed NCT NCT03117517
Treatment With Metformin and Combination of Metformin and Pioglitazone in Polycystic Ovarian Syndrome
Not yet reported Khyber Medical University Peshawar 106 participants Est. completion 2018-03-07 1 site Stand-aloneOther conditions: Polycystic Ovarian SyndromeView official trial listing → -
Terminated NCT NCT03118713
A Study to Evaluate the Renal Protective Effect (Urine Albumin-to-Creatinine Ratio (UACR)), Efficacy and Safety of Ipragliflozin in Type 2 Diabetes Mellitus Patients With Albuminuria
Not yet reported Astellas Pharma Korea, Inc. 33 participants Est. completion 2018-12-12 8 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT03122769
Cardiac Uptake of Metformin, Visualized by Positron Emission Tomography
Not yet reported Henrik Wiggers 6 participants Est. completion 2018-04-10 1 site Stand-aloneHeart failureView official trial listing → -
Completed NCT NCT03130426
Remission Evaluation of a Metabolic Intervention for Type 2 Diabetes With IGlarLixi
Not yet reported Population Health Research Institute 161 participants Est. completion 2020-09-30 8 sitesType 2 diabetesView official trial listing → -
Status unknown NCT NCT03137186
Repurposing Metformin as Anticancer Drug: in Advanced Prostate Cancer
Not yet reported Mansoura University 120 participants Est. completion 2020-01 1 siteOther conditions: Prostate CancerView official trial listing → -
Completed NCT NCT03141073
Long-term Efficacy and Safety of HMS5552 add-on to Metformin in T2DM Subjects
Not yet reported Hua Medicine Limited 767 participants Est. completion 2021-02-28 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT03151005
The Effect of GLP-1 Agonists Versus OCs on Reproductive Disorders and Cardiovascular Risks in Overweight PCOS
Not yet reported Xinqiao Hospital of Chongqing 70 participants Est. completion 2021-04-23 1 siteOther conditions: Polycystic Ovary Syndrome (PCOS), Overweight, ObesityView official trial listing → -
Completed NCT NCT03167918
Lung Function in Patients With Early Type 2 Diabetes Mellitus
Not yet reported, Not yet reported Liaoning University of Traditional Chinese Medicine 200 participants Est. completion 2017-05-01 Stand-aloneType 2 diabetes Other conditions: Pulmonary FunctionView official trial listing → -
Status unknown NCT NCT03184493
Celebrex and Metformin for Postoperative Hepatocellular Carcinoma
Not yet reported Guangxi Medical University 200 participants Est. completion 2021-06 1 site Stand-aloneOther conditions: Liver CancerView official trial listing → -
Completed NCT NCT03189407
Effect of Moringa Oleifera on Metformin Plasma Level in Type 2 Diabetes Mellitus Patients
Not yet reported Titilayo O Fakeye 25 participants Est. completion 2016-04-30Type 2 diabetesView official trial listing → -
Completed NCT NCT03189732
Effect of Metformin on Exercise-induced Lipolysis
Not yet reported Charles University, Czech Republic 10 participants Est. completion 2018-01 1 siteType 2 diabetesView official trial listing → -
Status unknown NCT NCT03192293
Metformin and Simvastatin in Addition to Fulvestrant
Not yet reported National University Hospital, Singapore 28 participants Est. completion 2019-01-20 1 site Stand-aloneOther conditions: Breast CancerView official trial listing → -
Status unknown NCT NCT03194009
PRuDENTE; Diabetes Prevention Via Exercise, Nutrition and Treatment
Not yet reported Instituto Nacional de Salud Publica, Mexico 3060 participants Est. completion 2022-12-31 1 siteType 2 diabetes Other conditions: Prediabetic StateView official trial listing → -
Completed NCT NCT03204058
Locally Delivered Metformin & Rosuvastatin for Treatment of Intrabony Defects in Chronic Periodontitis
Not yet reported, Not yet reported Government Dental College and Research Institute, Bangalore 90 participants Est. completion 2017-02-23Other conditions: Chronic PeriodontitisView official trial listing → -
Completed NCT NCT03204071
Locally Delivered Metformin and Aloe Vera for Treatment of Intrabody Defects in Chronic Periodontitis
Not yet reported, Not yet reported Government Dental College and Research Institute, Bangalore 90 participants Est. completion 2017-02Other conditions: Chronic PeriodontitisView official trial listing → -
Status unknown NCT NCT03204799
Metagenomic Analysis of Human Gut Microbiota in Patients With Metabolic Diseases Including Diabetes
Yonsei University 150 participants Est. completion 2019-12-16 1 siteType 2 diabetes Other conditions: DyslipidemiasView official trial listing → -
Completed NCT NCT03214380
A Study of LY900014 Compared to Insulin Lispro in Participants With Type 2 Diabetes
Not yet reported Eli Lilly and Company 933 participants Est. completion 2019-03-13 141 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT03225209
Medically Reproducing Bariatric Surgery
Not yet reported Moahad S Dar 5 participants Est. completion 2018-10-23 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT03235050
A Study to Evaluate the Efficacy and Safety of MEDI0382 in the Treatment of Overweight and Obese Subjects With Type 2 Diabetes
Not yet reported AstraZeneca 834 participants Est. completion 2019-06-14 119 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT03236740
OCP vs Metformin on Ovarian Stromal Blood Flow in PCOS
Not yet reported S.C.B. Medical College and Hospital 101 participants Est. completion 2018-03-15 1 siteOther conditions: PCOSView official trial listing → -
Status unknown NCT NCT03239119
The Effectivity and Safety Study of rExenatide-4 in Chinese Type 2 Diabetes Mellitus
Not yet reported CSPC ZhongQi Pharmaceutical Technology Co., Ltd. 456 participants Est. completion 2019-01-15Type 2 diabetesView official trial listing → -
Completed NCT NCT03283657
Diabetes Risk Education and Communication Trial
Not yet reported Northwestern University 53 participants Est. completion 2019-03-17 1 sitePrediabetesType 2 diabetes Other conditions: Diabetes Mellitus, Body Weight, Body Weight ChangesView official trial listing → -
Completed NCT NCT03312582
Locally Delivered 1% Metformin Gel in Peri-implantitis
Not yet reported King Saud University 46 participants Est. completion 2017-07-24Other conditions: Peri-ImplantitisView official trial listing → -
Terminated NCT NCT03349775
Cardiometabolic Disease and Pulmonary Hypertension
Not yet reported Massachusetts General Hospital 21 participants Est. completion 2020-12-22 1 siteOther conditions: ObesityView official trial listing → -
Completed NCT NCT03364335
The Effect Of NS-0200 and NS-0300 Versus Placebo on Weight In Obesity
Not yet reported NuSirt Biopharma 267 participants Est. completion 2018-08-17 15 sitesOther conditions: ObesityView official trial listing → -
Completed NCT NCT03378297
IMPACT: A Randomized WOO Study of Novel Therapeutic Agents in Women Triaged to Primary Surgery for EOC
Not yet reported Haukeland University Hospital 26 participants Est. completion 2023-01-05 2 sites Stand-aloneOther conditions: Ovarian CancerView official trial listing → -
Completed NCT NCT03416127
Effect of Propolis or Metformin Administration on Glycemic Control in Patients With Type 2 Diabetes Mellitus
Not yet reported University of Guadalajara 36 participants Est. completion 2019-12-20 1 site Stand-aloneType 2 diabetesView official trial listing → -
Terminated NCT NCT03419624
The Potential of Dapagliflozin Plus Exenatide in Obese Insulin-resistant Patients
Not yet reported Universitätsklinikum Hamburg-Eppendorf 13 participants Est. completion 2019-08-05 4 sites Added to GLP-1Type 2 diabetes Other conditions: ObesityView official trial listing → -
Status unknown NCT NCT03421119
Comparing Efficacy and Safety of CinnaGen-liraglutide Versus Victoza® in Patients With Type II Diabetes
Not yet reported Cinnagen 300 participants Est. completion 2019-12-01Type 2 diabetesView official trial listing → -
Completed NCT NCT03429543
Diabetes Study of Linagliptin and Empagliflozin in Children and Adolescents (DINAMO)TM
Not yet reported Boehringer Ingelheim 175 participants Est. completion 2023-05-31 83 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT03430856
Comparison of Insulin Tregopil (IN-105) With Insulin Aspart in Type 2 Diabetes Mellitus Patients
Not yet reported, Not yet reported Biocon Limited 143 participants Est. completion 2019-02-20 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT03441750
Efficacy of Metformin in Preventing Diabetes in China
Not yet reported Chinese Association of Geriatric Research 1724 participants Est. completion 2021-06-30 1 site Stand-alonePrediabetesView official trial listing → -
Terminated NCT NCT03451006
Effect of Metformin on Frailty in 12 Subjects
Not yet reported Mayo Clinic 7 participants Est. completion 2021-12-16 1 siteOther conditions: Aging, Inflammation, FrailtyView official trial listing → -
Completed NCT NCT03451734
Optimizing and Individualizing the Pharmacological Treatment of First-episode Schizophrenic Patients
Central South University 2000 participants Est. completion 2021-06-30 1 siteMetabolic syndrome Other conditions: SchizophreniaView official trial listing → -
Completed NCT NCT03458208
Bioequivalence Study of Metformin 1000 mg Tablets Immediate Release (IR) Versus Glucophage® 1000 mg Tablets IR In Healthy Subjects
Not yet reported Geropharm 18 participants Est. completion 2017-03-02 1 site Stand-aloneOther conditions: BioequivalenceView official trial listing → -
Terminated NCT NCT03477162
Metformin Pharmacology in Human Cancers: A Proof of Principle Study
Not yet reported Dartmouth-Hitchcock Medical Center 18 participants Est. completion 2021-11-30 1 site Stand-aloneOther conditions: Thoracic NeoplasmView official trial listing → -
Completed NCT NCT03479476
A Trial of Metformin in Individuals With Fragile X Syndrome
Not yet reported, Not yet reported University of California, Davis 120 participants Est. completion 2024-05-22 3 sitesOther conditions: Fragile X Syndrome, Fragile X Mental Retardation Syndrome, Mental Retardation, X Linked, Genetic Diseases, X-Linked, Trinucleotide Repeat Expansion, Fra(X) Syndrome, Intellectual Disability, FXS, Neurobehavioral Manifestations, Sex Chromosome DisordersView official trial listing → -
Completed NCT NCT03503942
The Pre-Diabetes Interventions and Continued Tracking to Ease-out Diabetes (Pre-DICTED) Program
Not yet reported Singapore General Hospital 751 participants Est. completion 2024-04-15 1 sitePrediabetesView official trial listing → -
Status unknown NCT NCT03507413
Metformin Therapy in Non-diabetic AAA Patients
Not yet reported, Not yet reported Medical University of Vienna 170 participants Est. completion 2024-05-01 1 siteOther conditions: Abdominal Aortic AneurysmView official trial listing → -
Status unknown NCT NCT03513874
Metformin Plus Insulin on Non-obese Autoimmune Diabetes
Not yet reported Second Xiangya Hospital of Central South University 15 participants Est. completion 2021-04-01 1 site Stand-aloneOther conditions: Type 1 Diabetes Mellitus, Autoimmune DiabetesView official trial listing → -
Status unknown NCT NCT03525028
A Clinical Trial of Metformin to Decrease Glucocorticoids Side Effects in Patients With Autoimmune Uveitis
Not yet reported Tianjin Medical University 138 participants Est. completion 2023-01-01 1 site Stand-aloneOther conditions: Uveitis, Metformin, GlucocorticoidView official trial listing → -
Status unknown NCT NCT03538704
Effect of Fertility-sparing Therapy of Early Endometrial Cancer
Not yet reported Peking University People's Hospital 80 participants Est. completion 2020-12-31 1 site Stand-aloneOther conditions: Endometrial Cancer, FertilityView official trial listing → -
Completed NCT NCT03555565
Specified Drug-Use Survey of Alogliptin and Metformin Hydrochloride Combination Tablets "Survey on Long-term Use in Type 2 Diabetes Mellitus Patients With Renal or Hepatic Impairment or Advanced Age"
Takeda 1026 participants Est. completion 2019-10-31 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT03558867
Personalised Medicine in Pre-diabetes and Early Type 2 Diabetes
Not yet reported Garvan Institute of Medical Research 138 participants Est. completion 2024-07-23 1 siteType 2 diabetes Other conditions: Pre DiabetesView official trial listing → -
Completed NCT NCT03566810
Glucophage Extended Release (GXR) China Bioequivalence Study (Nantong - Darmstadt)
Not yet reported Merck KGaA, Darmstadt, Germany 54 participants Est. completion 2018-11-28 1 siteOther conditions: HealthyView official trial listing → -
Completed NCT NCT03583385
Glucophage® Extended Release (XR) 750 Milligram (mg) Indonesia Bioequivalence (BE) Study
Not yet reported Merck KGaA, Darmstadt, Germany 48 participants Est. completion 2018-10-05 1 siteOther conditions: HealthyView official trial listing → -
Status unknown NCT NCT03585777
Compare Serum Klotho Levels in Patients on Oral Antidiabetic Treatment
Fayoum University 90 participants Est. completion 2019-03 1 siteOther conditions: Compare Serum Level of Klotho in Patients on Oral Antidiabetic TreatmentView official trial listing → -
Status unknown NCT NCT03590262
Effect of Metformin as add-on Therapy on Glycemic Control and Other Outcomes in Type 1 Diabetes
Not yet reported Shenzhen People's Hospital 20 participants Est. completion 2019-09-30 1 site Stand-aloneOther conditions: Type 1 Diabetes Mellitus, MetforminView official trial listing → -
Completed NCT NCT03593135
Effect of Apple Cider Vinegar in Type 2 Diabetics
Not yet reported Sheikh Zayed Federal Postgraduate Medical Institute 126 participants Est. completion 2017-11-14 1 site Stand-aloneOther conditions: Randomized Controlled Trial, Diabetes MellitusView official trial listing → -
Completed NCT NCT03596450
Long Term Comparative Effectiveness of Once Weekly Semaglutide Versus Standard of Care in a Real World Adult US Population With Type 2 Diabetes - a Randomized Pragmatic Trial
Not yet reported Novo Nordisk A/S 1278 participants Est. completion 2023-06-09 122 sitesType 2 diabetesView official trial listing → -
Active, not recruiting NCT NCT03603912
Targeting Risk Interventions and Metformin for Atrial Fibrillation (TRIM-AF)
Not yet reported Mina Chung, MD 175 participants Est. completion 2026-12 1 siteOther conditions: Atrial FibrillationView official trial listing → -
Completed NCT NCT03618654
Durvalumab With or Without Metformin in Treating Participants With Head and Neck Squamous Cell Carcinoma
Not yet reported Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University 38 participants Est. completion 2022-12-07 1 site Stand-aloneOther conditions: Head and Neck Squamous Cell Carcinoma, Oral Cavity Squamous Cell Carcinoma, Oropharyngeal Squamous Cell CarcinomaView official trial listing → -
Completed NCT NCT03629054
This Study in Healthy People Tests Whether Taking a Low Strength of Empagliflozin, Linagliptin, and Metformin Together in 1 Pill is the Same as Taking Them in Separate Pills
Not yet reported Boehringer Ingelheim 30 participants Est. completion 2018-11-05 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Status unknown NCT NCT03639545
The Effects of Empagliflozin on Arterial Wall Characteristics
Not yet reported University Medical Centre Ljubljana 120 participants Est. completion 2019-01-30 1 siteOther conditions: Vascular Stiffness, Hypoglycemic Agents, Diabetes Complications, Diabetes Mellitus, Type 1View official trial listing → -
Completed NCT NCT03651895
Metformin to Reduce Airway Glucose in COPD Patients
Not yet reported Imperial College London 14 participants Est. completion 2023-06-01 1 siteOther conditions: Chronic Obstructive Pulmonary DiseaseView official trial listing → -
Terminated NCT NCT03684642
Efficacy and Safety of Efpeglenatide Versus Dulaglutide in Patients With Type 2 Diabetes Mellitus Inadequately Controlled With Metformin
Not yet reported Sanofi 908 participants Est. completion 2020-11-17 45 sites Stand-aloneType 2 diabetesView official trial listing → -
Status unknown NCT NCT03685357
Correlation Between Idiopathic Parkinson's Disease and Diabetes Mellitus
Ain Shams University 120 participants Est. completion 2020-01 1 siteOther conditions: ObservationView official trial listing → -
Status unknown NCT NCT03685409
Cancer Chemoprevention by Metformin Hydrochloride in Oral Potentially Malignant Lesions
Not yet reported Cairo University 62 participants Est. completion 2020-09-30 1 siteOther conditions: Oral CancerView official trial listing → -
Status unknown NCT NCT03709147
Metformin Plus/Minus Fasting Mimicking Diet to Target the Metabolic Vulnerabilities of LKB1-inactive Lung Adenocarcinoma
Not yet reported Marina Garassino 64 participants Est. completion 2023-09-10 1 site Stand-aloneOther conditions: Advanced LKB1-inactive Lung AdenocarcinomaView official trial listing → -
Completed NCT NCT03711682
Reducing Plasma Glucose Effect of Cinnamon in Type 2 Diabetic Patients in the Municipality of Comasagua
Not yet reported, Not yet reported Universidad Dr. José Matías Delgado 30 participants Est. completion 2018-05-23 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT03713801
Impact of Metformin on Immunity
Not yet reported The University of Texas Health Science Center at San Antonio 18 participants Est. completion 2024-07-16 1 siteOther conditions: Aging, Vaccine Response ImpairedView official trial listing → -
Completed NCT NCT03714594
Effects of Dapagliflozin+Saxagliptin in Addition to Metformin v/s Saxagliptin or Dapagliflozin in Patients With DM2.
Not yet reported University of Pisa 48 participants Est. completion 2022-08-31 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT03717194
Effect of Ertugliflozin on Cardiac Function in Diabetes
Not yet reported Soo Lim 102 participants Est. completion 2023-04-30 1 site Stand-aloneType 2 diabetesHeart failureView official trial listing → -
Completed NCT NCT03733132
Metformin Effect on Brain Function in Insulin Resistant Elderly People
Not yet reported Mayo Clinic 40 participants Est. completion 2023-04-05 1 siteOther conditions: Insulin Resistance, Obesity, Obesity, AbdominalView official trial listing → -
Completed NCT NCT03748810
Head-to-head Comparison of Empagliflozin and Dapagliflozin
Chungbuk National University Hospital 600 participants Est. completion 2022-06-30 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT03756623
Effect of Metformin and Probiotics on Gut Microbiome in Healthy Subjects
Not yet reported The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School 90 participants Est. completion 2019-06-30 1 siteOther conditions: HealthyView official trial listing → -
Completed NCT NCT03765359
Metformin Use to Improve Pregnancy Outcome in Women With Type 1 Diabetes.
Not yet reported Tampere University Hospital 101 participants Est. completion 2022-12-19 5 sitesOther conditions: Diabetic Pregnancy, Insulin Resistance, Type1diabetesView official trial listing → -
Completed NCT NCT03766256
Shared Decision Making in Diabetes Prevention for Women With a History of GDM
Not yet reported University of California, Los Angeles 33 participants Est. completion 2019-12-28 20 sites Stand-aloneOther conditions: Gestational DiabetesView official trial listing → -
Completed NCT NCT03766308
The Clinical Study of the Effect of Highland Barley Diet on Blood Glucose in Patients With Type 2 Diabetes Mellitus
Not yet reported Xuefeng Yu 40 participants Est. completion 2020-12-31 1 site Stand-aloneType 2 diabetesView official trial listing → -
Terminated NCT NCT03770728
Efficacy and Safety of Efpeglenatide Versus Placebo in Patients With Type 2 Diabetes Mellitus Inadequately Controlled With Metformin Alone or in Combination With Sulfonylurea
Not yet reported Sanofi 312 participants Est. completion 2020-12-27 48 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT03772262
Assessing Goldenseal-drug Interactions Using a Probe Drug Cocktail Approach
Not yet reported Washington State University 16 participants Est. completion 2019-03-31 1 site Stand-aloneOther conditions: Interaction Drug FoodView official trial listing → -
Completed NCT NCT03772964
Effects of Metformin in a Non-Diabetic Patient Population
Not yet reported, Not yet reported Brian Zuckerbraun 32 participants Est. completion 2020-03-31 1 siteOther conditions: Inflammatory ResponseView official trial listing → -
Status unknown NCT NCT03774108
Metformin and Systemic Inflammation in HIV
Not yet reported Hospital Civil de Guadalajara 40 participants Est. completion 2020-01-08 1 site Stand-alonePrediabetes Other conditions: HIV-1-infectionView official trial listing → -
Completed NCT NCT03787017
A Study to Compare MP-513 20mg & Metformin XR 1000mg FDC With Coadministration of the Two Separate Drugs
Not yet reported Handok Inc. 36 participants Est. completion 2014-09 1 siteOther conditions: Healthy VolunteersView official trial listing → -
Completed NCT NCT03787043
A Study to Evaluate the Effect of Food on Fixed-Dose Combination of MP-513 10 mg and Metformin XR 750 mg
Not yet reported Handok Inc. 30 participants Est. completion 2014-06 1 siteOther conditions: Healthy VolunteersView official trial listing → -
Completed NCT NCT03800602
Nivolumab and Metformin in Patients With Treatment Refractory MSS Colorectal Cancer
Not yet reported Emory University 29 participants Est. completion 2021-09-04 3 sites Stand-aloneObstructive sleep apnea Other conditions: Colorectal Adenocarcinoma, Refractory Colorectal Carcinoma, Stage IV Colorectal Cancer, Stage IVA Colorectal Cancer, Stage IVB Colorectal Cancer, Stage IVC Colorectal Cancer, Colorectal Cancer MetastaticView official trial listing → -
Withdrawn NCT NCT03813316
Approaches To Therapy Escalation In T2D
Not yet reported LMC Diabetes & Endocrinology Ltd. Est. completion 2019-09-18 Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT03824002
Dulaglutide in Diabetic Patients, Relationship Between Arterial Stiffness, Endothelial Function, Clinical and Laboratory Variables
Not yet reported University of Palermo 92 participants Est. completion 2018-04-20 1 site Added to GLP-1Other conditions: Diabetes MellitusView official trial listing → -
Status unknown NCT NCT03833466
Metformin in Combined With Cisplatin Plus Paclitaxel With Advanced Esophageal Squamous Cell Carcinoma (ECMTPneo)
Not yet reported Peking University 15 participants Est. completion 2020-06-20 1 site Stand-aloneOther conditions: Esophageal Squamous Cell CarcinomaView official trial listing → -
Completed NCT NCT03842267
A Study to Evaluate the Efficacy and Safety of Gemigliptin in Type 2 Diabetes Who Have Inadequate GlycemIc Control With Dapagliflozin and Metformin (SOLUTION Study)
Not yet reported LG Chem 315 participants Est. completion 2022-11-30 1 siteType 2 diabetesView official trial listing → -
Status unknown NCT NCT03851432
Janagliflozin Treat Type 2 Diabetes Mellitus (T2DM) Inadequately Controlled With Metformin
Not yet reported Sihuan Pharmaceutical Holdings Group Ltd. 390 participants Est. completion 2021-12-31 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT03862963
Lifestyle Intervention to Treat Diabetes in the Marshall Islands
Not yet reported University of Alabama at Birmingham 138 participants Est. completion 2008-07-31Type 2 diabetesView official trial listing → -
Completed NCT NCT03871621
Left Ventricular Functional Changes of Uncontrolled Diabetes by Dapagliflozin Treatment Trial
Not yet reported Mackay Memorial Hospital 76 participants Est. completion 2022-08-31 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT03898037
Effect of Lifestyle and/or Metformin Intervention on Pregnancy Outcome, A Pilot Randomized Controlled Trial
Not yet reported Reproductive & Genetic Hospital of CITIC-Xiangya 80 participants Est. completion 2021-06-30 1 site Stand-aloneOther conditions: Infertility, Female, Obesity, Insulin ResistanceView official trial listing → -
Completed NCT NCT03916263
Low Starch Dietary Education Program vs. Traditional Treatment for PCOS
Not yet reported Texas Tech University Health Sciences Center 71 participants Est. completion 2022-12-31 1 siteOther conditions: PCOS, Diet Modification, Metabolism, Nutrition DisordersView official trial listing → -
Completed NCT NCT03921242
Comparative Effectiveness of Metformin for Type 2 Diabetes With Chronic Kidney Disease
Weill Medical College of Cornell University 4888 participants Est. completion 2023-08-01 2 sitesType 2 diabetes Other conditions: Renal Insufficiency, ChronicView official trial listing → -
Completed NCT NCT03945656
A Research Study of How Overdosing of a New Once Weekly Medicine NNC0148-0287 C (Insulin 287) Influences the Blood Sugar Level in People With Type 2 Diabetes
Not yet reported Novo Nordisk A/S 43 participants Est. completion 2021-09-27 1 siteType 2 diabetesView official trial listing → -
Status unknown NCT NCT03950505
To Evaluate the Effect of Nesinaact on Non-alcoholic Steatohepatitis Through MRI and Liver Fibroscan in Patients With Type 2 Diabetes
Not yet reported Yonsei University 60 participants Est. completion 2020-12 1 siteType 2 diabetes Other conditions: Non-alcoholic SteatohepatitisView official trial listing → -
Completed NCT NCT03956290
Time Restricted EATing (TREAT) Pilot Study
Not yet reported Columbia University 64 participants Est. completion 2021-01-11 1 siteOther conditions: Overweight and Obesity, Pre DiabetesView official trial listing → -
Completed NCT NCT03967496
Assessment of Immediate Postoperative Delirium (IPD) in Adult Patients: Incidence and Etiologic Factors
Sultan Qaboos University 402 participants Est. completion 2019-03-31 1 siteOther conditions: Delirium, Anesthesia; Adverse EffectView official trial listing → -
Completed NCT NCT03969719
A Double-blind Study to Assess 2 Doses of an Investigational Product for 16 Weeks in Participants With Non-alcoholic Fatty Liver Disease and Type 2 Diabetes Mellitus
Not yet reported Pfizer 164 participants Est. completion 2021-03-30 106 sitesOther conditions: Non-alcoholic SteatohepatitisView official trial listing → -
Status unknown NCT NCT03994744
Assessing Safety and Efficacy of Sintilimab and Metformin Combination Therapy in SCLC
Not yet reported Hunan Cancer Hospital 68 participants Est. completion 2022-07-01 1 site Stand-aloneOther conditions: Small-cell Lung Cancer, Small Cell Lung Carcinoma, Small Cell Lung Cancer Recurrent, Small Cell Lung Cancer Extensive StageView official trial listing → -
Completed NCT NCT04009603
Comparison of Probiotics, Metformin & Their Combination Therapy in the Treatment of PCOS
Not yet reported Ziauddin University 78 participants Est. completion 2020-01-28 1 siteOther conditions: Polycystic Ovary SyndromeView official trial listing → -
Status unknown NCT NCT04029272
Metformin vs Metformin Combined With GLP-1RA (Glucagon-like Peptide 1 Receptor Agonist) on Overweight/Obese PCOS Patients
Not yet reported Peking Union Medical College Hospital 80 participants Est. completion 2020-12-31 1 siteOther conditions: Polycystic Ovary SyndromeView official trial listing → -
Completed NCT NCT04029480
Ertugliflozin Type 2 Diabetes Mellitus (T2DM) Pediatric Study (MK-8835/PF-04971729) (MK-8835-059)
Not yet reported Merck Sharp & Dohme LLC 166 participants Est. completion 2025-04-11 104 sites Stand-aloneType 2 diabetesView official trial listing → -
Status unknown NCT NCT04033107
High Dose Vitamin C Combined With Metformin in the Treatment of Malignant Tumors
Not yet reported Zhongnan Hospital 30 participants Est. completion 2024-12 1 siteOther conditions: Hepatocellular Cancer, Pancreatic Cancer, Gastric Cancer, Colorectal CancerView official trial listing → -
Completed NCT NCT04043221
Long Term Metformin in Women With Polycystic Ovary Syndrome
University Medical Centre Ljubljana 180 participants Est. completion 2019-01-01 1 siteOther conditions: Polycystic Ovary SyndromeView official trial listing → -
Completed NCT NCT04075110
Investigation the Safety and Efficacy of The Antileukotriene Agents, Montelukast, as Adjuvant Therapy in Obese Patients With Type 2 Diabetes Mellitus
Not yet reported Sadat City University 100 participants Est. completion 2023-04-10 1 site Stand-aloneOther conditions: Obesity; Endocrine; Diabetes Type 2View official trial listing → -
Completed NCT NCT04081857
A Study to Evaluate the Pharmacokinetics and Safety of HCP1704 in Healthy Subjects
Not yet reported Hanmi Pharmaceutical Company Limited 48 participants Est. completion 2019-08-05 1 site Stand-aloneOther conditions: Health, SubjectiveView official trial listing → -
Status unknown NCT NCT04089813
Effect of Metformin on Chronic Pain After Thoracic Surgery in Diabetic Patients
Xuzhou Medical University 200 participants Est. completion 2020-12-31 1 siteOther conditions: Postoperative Chronic PainView official trial listing → -
Completed NCT NCT04120259
Effect of Apple Cider Vinegar and Metformin Combination vs Metformin Alone in Type 2 Diabetics
Not yet reported Ziauddin University 126 participants Est. completion 2019-08-26 1 site Stand-aloneType 2 diabetesView official trial listing → -
Status unknown NCT NCT04131582
Effect of Empagliflozin + Linagliptin + Metformin + Lifestyle in Patients With Prediabetes
Not yet reported Universidad de Guanajuato 34 participants Est. completion 2020-12-30 1 site Stand-aloneOther conditions: Prediabetic State, Insulin ResistanceView official trial listing → -
Status unknown NCT NCT04134650
Effect of Low Dose Combination of Linagliptin + Metformin to Prevent Diabetes
Not yet reported Universidad de Guanajuato 34 participants Est. completion 2020-07-01 1 site Stand-aloneOther conditions: Prediabetic State, Insulin ResistanceView official trial listing → -
Status unknown NCT NCT04141163
Metformin in Patients With Fragile X
Not yet reported, Not yet reported Rowan University 40 participants Est. completion 2021-03 1 siteOther conditions: Fragile X SyndromeView official trial listing → -
Completed NCT NCT04183868
Effects of empagliFlozin on myocardIal metabOlic Rate of glucosE Estimated Through 18FDG PET (FIORE Study)
Not yet reported University of Catanzaro 26 participants Est. completion 2021-10 1 site Stand-aloneType 2 diabetes Other conditions: Cardiovascular Risk FactorView official trial listing → -
Status unknown NCT NCT04195243
Dapagliflozin vs Empagliflozin on Flow Mediated Dilation in Type 2 Diabetes Mellitus
Not yet reported Centro Universitario de Ciencias de la Salud, Mexico 24 participants Est. completion 2020-12-30 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT04231435
Influence of Fedratinib on the Pharmacokinetics of the Transporter Probe Substrates Digoxin, Rosuvastatin, and Metformin
Not yet reported Celgene 24 participants Est. completion 2020-02-21 1 site Stand-aloneOther conditions: Healthy VolunteersView official trial listing → -
Status unknown NCT NCT04248998
Calorie Restriction With or Without Metformin in Triple Negative Breast Cancer
Not yet reported Fondazione IRCCS Istituto Nazionale dei Tumori, Milano 30 participants Est. completion 2024-05-01 1 site Stand-aloneOther conditions: Triple-negative Breast CancerView official trial listing → -
Status unknown NCT NCT04255238
A Study to Evaluate the Efficacy and Safety of Dual add-on Therapy With Gemigliptin 50 mg and Dapagliflozin 10 mg Added to Metformin Who Have Inadequate Glycemic Control on Metformin Alone
Not yet reported LG Chem 468 participants Est. completion 2022-12-30Type 2 diabetesView official trial listing → -
Status unknown NCT NCT04268563
Comparing the Effect of Sitagliptin/Metformin and Metformin in PCOS Patients
Not yet reported, Not yet reported Shahid Beheshti University of Medical Sciences 80 participants Est. completion 2021-07-30 1 siteOther conditions: Polycystic Ovary Syndrome, Infertility, ARTView official trial listing → -
Completed NCT NCT04271189
Managing DIabetes Remission After Combined Therapy in EarLy Stage of DiabetEs
Not yet reported Azienda Ospedaliero-Universitaria di Parma 108 participants Est. completion 2024-12-31 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT04283318
Prolonged Fasting on Glucose Metabolism and Hormonal Regulation in Healthy, Obese and Subjects With Type 2 Diabetes
Not yet reported Medical University of Graz 80 participants Est. completion 2022-02-28 1 siteType 2 diabetes Other conditions: Healthy, Obesity, Type 1 DiabetesView official trial listing → -
Status unknown NCT NCT04287387
Response of Gut Microbiota in Type 2 Diabetes to Hypoglycemic Agents
Not yet reported Peking Union Medical College Hospital 180 participants Est. completion 2021-03-02 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT04288778
A Study to Assess Safety of Canagliflozin and Metformin Hydrochloride Combination Given as a Supplement to Diet and Exercise to Improve Blood Sugar Level in Indian Adult Participants With Diabetes
Not yet reported Johnson & Johnson Private Limited 276 participants Est. completion 2022-07-26 10 sites Stand-aloneOther conditions: Diabetes MellitusView official trial listing → -
Status unknown NCT NCT04298684
Efficacy of Metformin Versus Sitagliptin on Benign Thyroid Nodules in Type 2 Diabetes
Not yet reported Centre Hospitalier Universitaire de la Guadeloupe 90 participants Est. completion 2024-07-01 4 sites Stand-aloneType 2 diabetes Other conditions: Thyroid Nodule (Benign)View official trial listing → -
Completed NCT NCT04335526
A Clinical Study to Assess the Effect of Change of Bile Acid on the PD and Safety of Metformin and Microbiome Profiles
Not yet reported Seoul National University Hospital 15 participants Est. completion 2020-10-21 1 siteOther conditions: Human MicrobiomeView official trial listing → -
Active, not recruiting NCT NCT04341571
Effect of Probiotics Versus Metformin on Glycemic Control, Insulin Sensitivity and Insulin Secretion in Prediabetes.
Not yet reported University of Guadalajara 30 participants Est. completion 2026-12 1 sitePrediabetes Other conditions: Hyperglycemia, Resistance, InsulinView official trial listing → -
Status unknown NCT NCT04390295
Efficacy and Safety of SHR3824 in Combination With Metformin in Subjects With Type 2 Diabetes
Not yet reported Jiangsu HengRui Medicine Co., Ltd. 450 participants Est. completion 2020-05 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT04392284
Developing an Adaptive Lifestyle Intervention Program in Family Medicine Clinics
Not yet reported University of Alabama at Birmingham 40 participants Est. completion 2022-06-03 1 site Stand-aloneMetabolic syndrome Other conditions: Insulin Resistance, Obesity, Diabetes, Hypertension, DyslipidemiasView official trial listing → -
Active, not recruiting NCT NCT04407650
Ursodeoxycholic Acid vs Metformin in Gestational Diabetes Mellitus
Not yet reported King's College London 64 participants Est. completion 2025-05-31 1 siteOther conditions: Gestational DiabetesView official trial listing → -
Status unknown NCT NCT04412746
Covid-19 and Diabetes in West of Algeria
Laboratoire De Recherche Sur Le Diabete, Université de Tlemcen 100 participants Est. completion 2020-06-30 1 siteOther conditions: Coronavirus Infections, Diabetes Mellitus, Prevalence, Risk Factors, Patient Outcome Assessment, Severe Acute Respiratory SyndromeView official trial listing → -
Completed NCT NCT04465877
Study to Evaluate Safety, Tolerability, Pharmacokinetics & Pharmacodynamics of JTT-662 in Subjects With Type 2 Diabetes
Not yet reported Akros Pharma Inc. 37 participants Est. completion 2021-02-17 1 siteType 2 diabetesView official trial listing → -
Status unknown NCT NCT04477590
Interactions of Medicine and Exercise With Meal Timing
Not yet reported University of Castilla-La Mancha 160 participants Est. completion 2024-12-30 1 siteMetabolic syndrome Other conditions: Exercise Training, Metformin, Statins, Angiotensin-Converting-Enzyme Inhibitor, Fasting, Intermittent, Angiotensin HypertensionView official trial listing → -
Completed NCT NCT04497792
Safety and Efficacy of Empagliflozin for Patients With Diabetes Mellitus and Planned Percutaneous Coronary Interventions
Not yet reported Research Institute for Complex Problems of Cardiovascular Diseases, Russia 40 participants Est. completion 2019-11Cardiovascular disease Other conditions: Diabetes Mellitus, Percutaneous Coronary InterventionView official trial listing → -
Status unknown NCT NCT04508634
Treating Obese PCOS Patients With LSG vs. Met
Not yet reported Shanghai 10th People's Hospital 90 participants Est. completion 2024-09-30 1 siteOther conditions: Polycystic Ovary SyndromeView official trial listing → -
Completed NCT NCT04521049
Tubular Markers in Response to Saxagliptin Therapy
Not yet reported Beni-Suef University 80 participants Est. completion 2020-04-01 1 siteType 2 diabetesView official trial listing → -
Active, not recruiting NCT NCT04536805
Relapse in Previously Irradiated Prostate Bed : Stereotactic Ablative Reirradiation Potentiated by Metformin
Not yet reported, Not yet reported Institut Cancerologie de l'Ouest 44 participants Est. completion 2031-11 12 sites Stand-aloneOther conditions: Prostate CancerView official trial listing → -
Active, not recruiting NCT NCT04545736
Oral Metformin for Treatment of ABCA4 Retinopathy
Not yet reported, Not yet reported National Eye Institute (NEI) 55 participants Est. completion 2029-02-02 2 sites Stand-aloneOther conditions: ABCA4 Retinopathy, Stargardt Disease, Retinal Dystrophy, Retinal DegenerationView official trial listing → -
Status unknown NCT NCT04559308
The Effect of Metformin on Breast Cancer Patients
Not yet reported Beni-Suef University 80 participants Est. completion 2020-10 1 site Stand-aloneOther conditions: Breast CancerView official trial listing → -
Active, not recruiting NCT NCT04576104
Megestrol Acetate Compared With Megestrol Acetate and Metformin to Prevent Endometrial Cancer
Not yet reported Northwestern University 51 participants Est. completion 2026-06-30 8 sitesOther conditions: Endometrial Atypical Hyperplasia/Endometrioid Intraepithelial Neoplasia, Endometrial CarcinomaView official trial listing → -
Completed NCT NCT04617275
A 12-WEEK TITRATE STUDY TO EVALUATE SAFETY, TOLERABILITY AND PHARMACODYNAMICS OF PF-06882961 IN ADULTS WITH TYPE 2 DIABETES MELLITUS AND IN NON-DIABETIC ADULTS WITH OBESITY
Not yet reported Pfizer 151 participants Est. completion 2021-11-17 38 sitesOther conditions: Diabetes, ObesityView official trial listing → -
Completed NCT NCT04622111
Safety and Pharmacokinetics Study of CPL207280 Compound in Healthy Volunteers.
Not yet reported Celon Pharma SA 68 participants Est. completion 2021-05-05 1 site Stand-aloneOther conditions: Healthy VolunteersView official trial listing → -
Status unknown NCT NCT04623567
Efficacy Assessment of Chinese Herbal Medicine Jiangtang Tiaozhi Recipe Treating Participants With Glucose and Lipid Metabolism Disturbances
Not yet reported, Not yet reported Guang'anmen Hospital of China Academy of Chinese Medical Sciences 96 participants Est. completion 2024-06-30 1 siteType 2 diabetes Other conditions: DyslipidemiasView official trial listing → -
Status unknown NCT NCT04653779
A Clinical Trial to Evaluate the Preference Regarding Convenience of Medication and Efficacy/Safety of SUGAMET®XR Tablet 5/1000mg
Not yet reported Dong-A ST Co., Ltd. 54 participants Est. completion 2021-07 2 sites Stand-aloneType 2 diabetes Other conditions: Renal Disease, Diabetes Mellitus, Metabolic Disease, Endocrine System DiseasesView official trial listing → -
Completed NCT NCT04654676
DPP4 Inhibitor on Glycemic Variability
Not yet reported University Malaysia Sarawak 12 participants Est. completion 2019-08-31 1 siteType 2 diabetesView official trial listing → -
Withdrawn NCT NCT04662164
A Study to Access the Efficacy in Type 2 Diabetes Mellitus on Stable Metformin
Not yet reported, Not yet reported Shanghai HEP Pharmaceutical Co., Ltd. Est. completion 2025-12Type 2 diabetesView official trial listing → -
Status unknown NCT NCT04667143
Dual Add-on Therapy in Type 2 Diabetes Poorly Controlled With Metformin Monotherapy
Not yet reported Jiangsu HengRui Medicine Co., Ltd. 760 participants Est. completion 2022-10Other conditions: Diabetes Mellitus, Type IIView official trial listing → -
Status unknown NCT NCT04672031
Glycemic Targets for Pregnant Women With GDM and T2DM
Not yet reported University of Southern California 120 participants Est. completion 2023-07 1 site Stand-aloneType 2 diabetes Other conditions: Diabetes Mellitus in Pregnancy, Diabetes, GestationalView official trial listing → -
Completed NCT NCT04706377
Vitamin B12 Supplementation in Diabetic Neuropathy
Not yet reported Aristotle University Of Thessaloniki 90 participants Est. completion 2020-02-28 1 siteOther conditions: Diabetes Mellitus, Diabetic Neuropathies, Diabetic Complication, Diabetic FootView official trial listing → -
Withdrawn NCT NCT04741204
Metformin Use to Reduce Disparities in Newly Diagnosed Breast Cancer
Not yet reported Woman's Est. completion 2022-09 1 siteOther conditions: Breast Cancer Stage, Insulin Resistance, Racial BiasView official trial listing → -
Terminated NCT NCT04754334
A Phase 3 Study to Evaluate the Efficacy and Safety of ORMD-0801 in Subjects With Type 2 Diabetes Mellitus
Not yet reported Oramed, Ltd. 346 participants Est. completion 2023-01-13 1 siteType 2 diabetesView official trial listing → -
Status unknown NCT NCT04762966
Study of Metformin Overdose
Central Hospital, Nancy, France 50 participants Est. completion 2021-09-01 1 siteOther conditions: Metformin Associated Lactic AcidosisView official trial listing → -
Status unknown NCT NCT04799938
Effect of Exercise on GDF-15 Levels in Prediabetic Patients
Not yet reported Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey 70 participants Est. completion 2023-04-01 1 sitePrediabetesView official trial listing → -
Status unknown NCT NCT04817215
Phase 3 Study to Evaluate the Efficacy and Safety of ORMD-0801 in Subjects With Type 2 Diabetes Mellitus
Not yet reported King Hamad University Hospital, Bahrain 608 participants Est. completion 2022-07 Stand-aloneType 2 diabetesView official trial listing → -
Not yet recruiting NCT NCT04836910
Microbiome and Polycystic Ovaries
Sheba Medical Center 40 participants Est. completion 2027-03-30 1 siteOther conditions: Polycystic Ovary Syndrome, Microbial ColonizationView official trial listing → -
Completed NCT NCT04841668
Gut-Brain-axis: Targets for Improvement of Cognition in the Elderly
Institut d'Investigació Biomèdica de Girona Dr. Josep Trueta 50 participants Est. completion 2024-12-03 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT04865835
A Clinical Trial Study to Determine the Effect of an Investigational Drug (SEP-363856) Has on the Way That the Drug Metformin Travels Through the Body in People With Schizophrenia.
Not yet reported Otsuka Pharmaceutical Development & Commercialization, Inc. 21 participants Est. completion 2022-05-03 2 sites Stand-aloneOther conditions: SchizophreniaView official trial listing → -
Status unknown NCT NCT04882332
Metformin Usage Index and Vitamin B12 Status in Egyptian Type 2 Diabetic Patients
Cairo University 108 participants Est. completion 2022-10 1 siteOther conditions: Diabetes MellitusView official trial listing → -
Completed NCT NCT04885712
A Study to Evaluate the Efficacy and Safety of Pioglitazone 15mg or 30mg Add-on in Patients With Type 2 Diabetes Mellitus Inadequately Controlled With Metformin and Dapagliflozin
Not yet reported Boryung Pharmaceutical Co., Ltd 378 participants Est. completion 2023-03-10 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT04902326
Behavioral Economics and Self-Determination Theory to Change Diabetes Risk (BEST Change)
Not yet reported University of Michigan 380 participants Est. completion 2023-09-18 1 site Stand-aloneOther conditions: Pre DiabetesView official trial listing → -
Completed NCT NCT04916093
Safety and Efficacy of Antidiabetic Drugs in Recently Diagnosed Patients With Type 2 Diabetes
Not yet reported Beni-Suef University 60 participants Est. completion 2020-12-15 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT04931147
A 3-part Study to Evaluate Safety, Tolerability, Food Effect and Drug-drug Interactions of RXC007 in Healthy Volunteers
Not yet reported Redx Pharma Ltd 90 participants Est. completion 2023-03-08 1 siteOther conditions: Fibrosis, Inflammation, Idiopathic Pulmonary Fibrosis, Non-alcoholic Steatohepatitis, Liver Diseases, Kidney DiseasesView official trial listing → -
Status unknown NCT NCT04984070
Research on Risk Factors and Interventions of Polycystic Ovary Syndrome Complicated With Depression and Anxiety
Not yet reported Fudan University 100 participants Est. completion 2024-12-31 1 siteOther conditions: PCOS (Polycystic Ovary Syndrome) of Bilateral Ovaries, Depression, AnxietyView official trial listing → -
Status unknown NCT NCT05025852
The Effect of In-utero Exposure to Metformin in 5-11 Year Old Offspring of Mothers in the MiTy Trial
Mount Sinai Hospital, Canada 220 participants Est. completion 2026-05 12 sitesType 2 diabetes Other conditions: Pregnancy in Diabetic, Child Obesity, Child DevelopmentView official trial listing → -
Status unknown NCT NCT05032001
ORAL ANTIDIABETICS EFFECT ON VISCERAL FAT
Not yet reported Metabolic Research Unit 30 participants Est. completion 2022-08-01 1 siteType 2 diabetes Other conditions: Abdominal ObesityView official trial listing → -
Completed NCT NCT05055219
Conventional and Metabolomic Predictors of Prediabetes & Insulin Resistance
University of Michigan 772 participants Est. completion 2020-02-19 1 sitePrediabetes Other conditions: Obesity, ChildhoodView official trial listing → -
Withdrawn NCT NCT05102071
Clinical Outcomes and Healthcare Cost and Resource Utilization (HCRU) in Patients With Type 2 Diabetes and Cardiovascular Disease on 2nd Line Empagliflozin Versus 2nd Line Sulfonylureas
Boehringer Ingelheim Est. completion 2022-06-15 1 siteType 2 diabetesCardiovascular diseaseView official trial listing → -
Completed NCT NCT05124730
Fasting Bioequivalence Study of 2 Metformin 500 mg Prolonged Release Tablets in 44 Healthy Male and Female Volunteers
Not yet reported Joint Stock Company "Farmak" 44 participants Est. completion 2021-05-29 1 site Stand-aloneOther conditions: PharmacokineticsView official trial listing → -
Completed NCT NCT05132023
Bioequivalence Study of Empagliflozin & Metformin HCL From Empagliform 12.5/1000 mg F.C.T (Hikma Pharma, Egypt) and Synjardy 12.5/1000 mg F.C.T (Boehringer Ingelheim International GmbH, Germany)
Not yet reported Genuine Research Center, Egypt 26 participants Est. completion 2019-05-15 1 siteOther conditions: HealthyView official trial listing → -
Status unknown NCT NCT05162690
Efficacy of Dapagliflozin in Diabetes Associated Peripheral Neuropathy
Not yet reported, Not yet reported Post Graduate Institute of Medical Education and Research, Chandigarh 40 participants Est. completion 2023-12-31 1 siteOther conditions: Diabetic Peripheral NeuropathyView official trial listing → -
Suspended NCT NCT05183204
Paxalisib With a High Fat, Low Carb Diet and Metformin for Glioblastoma
Not yet reported Weill Medical College of Cornell University 33 participants Est. completion 2026-06 1 site Stand-aloneOther conditions: GlioblastomaView official trial listing → -
Status unknown NCT NCT05200793
Efficacy of Empagliflozin or Linagliptin as an Alternative to Metformin for Treatment of Polycystic Ovary Syndrome
Not yet reported Alexandria University 75 participants Est. completion 2022-09-01 1 siteOther conditions: Polycystic Ovary Syndrome (PCOS)View official trial listing → -
Status unknown NCT NCT05226897
Clinical Trial to Assess the Efficacy and Safety of YYC405 in Type 2 Diabetes Patients
Not yet reported Yooyoung Pharmaceutical Co., Ltd. 256 participants Est. completion 2023-06-26 1 siteType 2 diabetesView official trial listing → -
Status unknown NCT NCT05232994
Metformin and Esomeprazole For Preterm Pre-eclampsia
Not yet reported Christiana Care Health Services 38 participants Est. completion 2025-12-31 1 site Stand-aloneOther conditions: Preeclampsia Severe, Preeclampsia Second Trimester, Preterm Birth ComplicationView official trial listing → -
Completed NCT NCT05233514
Effect of Aerobic Exercise on Polycystic Ovary Syndrome
Not yet reported Cairo University 40 participants Est. completion 2021-12-10 1 site Stand-aloneOther conditions: Polycystic Ovary SyndromeView official trial listing → -
Completed NCT NCT05280496
A Pragmatic Approach to Lower Diabetes Risk After Gestational Diabetes
Not yet reported Tufts Medical Center 20 participants Est. completion 2025-04-18 1 site Stand-alonePrediabetesType 2 diabetes Other conditions: Diabetes, GestationalView official trial listing → -
Status unknown NCT NCT05296044
To Evaluate the Efficacy and Safety of JT-003 add-on in Patients With Type 2 Diabetes Mellitus Inadequately Controlled With Metformin and Dapagliflozin
Not yet reported Jeil Pharmaceutical Co., Ltd. 245 participants Est. completion 2024-02-28 1 siteType 2 diabetesView official trial listing → -
Status unknown NCT NCT05305898
"MetCool ACS"- Metformin "Cooling" Effect on Metformin-naive Patients Treated With PCI Because of Acute Coronary Syndrome
Not yet reported Military Institute od Medicine National Research Institute 2000 participants Est. completion 2025-12 14 sites Stand-aloneOther conditions: Acute Coronary SyndromeView official trial listing → -
Status unknown NCT NCT05326490
Study to Evaluate the Efficacy and Safety of PB-201 in Type 2 Diabetic Mellitus Patients With Poor Glycemic Control Via Metformin Hydrochloride Monotherapy
Not yet reported PegBio Co., Ltd. 546 participants Est. completion 2024-10-31 1 siteType 2 diabetesView official trial listing → -
Status unknown NCT NCT05326984
Effect of Metformin on ABCB1 and AMPK Expression in Adolescents With Newly Diagnosed Acute Lymphoblastic Leukemia
Not yet reported Hospital General de Mexico 20 participants Est. completion 2023-12 1 siteOther conditions: Acute Lymphoblastic LeukemiaView official trial listing → -
Completed NCT NCT05329857
The Study Intends to Show Bioequivalence of the Test Product and the Reference Reference Product in a Crossover Design Study Healthy Volunteers. Additionally, the Safety Profile of Test Product Compared to Reference Product Will be Evaluated.
Not yet reported AET Laboratories Private Limited 60 participants Est. completion 2016-03Other conditions: To Determine Bioequivalence Under Fed ConditionsView official trial listing → -
Completed NCT NCT05332795
The Impact of Metformin on the Outcome of Gouty Arthritis in a Cohort of Egyptian Gouty Patients.
Not yet reported Menoufia University 100 participants Est. completion 2024-02-20 1 siteOther conditions: Gouty ArthritisView official trial listing → -
Completed NCT NCT05343767
Investigate the Efficacy and Safety of Low-Glu in Patients Newly Diagnosed With Type II Diabetes Mellitus
Not yet reported Natural Wellness Egypt 198 participants Est. completion 2021-05-30 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT05360147
Liraglutide Improve Cognitive Function in Patients With Type 2 Diabetes Mellitus
Not yet reported Third Military Medical University 30 participants Est. completion 2021-05-10 1 siteType 2 diabetesView official trial listing → -
Status unknown NCT NCT05362799
Different Induction Protocols in PCOS After Clomiphene Citrate Failed Pregnancy in Non-IVF Cycles
Not yet reported Menoufia University 176 participants Est. completion 2023-12-31Other conditions: Infertility, FemaleView official trial listing → -
Completed NCT NCT05363384
A Bioequivalence Study of CT-L01 Compared to Co-administration (ALO 25 mg and MET XR 1,000 mg) in Healthy Volunteers
Not yet reported Celltrion 48 participants Est. completion 2022-07-12 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT05364164
A Food Effect Study of CT-L01 After Oral Administration in Healthy Volunteers
Not yet reported Celltrion 24 participants Est. completion 2022-07-25 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT05365451
Pharmacokinetic Drug-Drug Interaction Study to Identify Biomarkers of Kidney Transporters
Not yet reported Washington State University 16 participants Est. completion 2023-07-22 1 site Stand-aloneOther conditions: Interaction, Endogenous BiomarkersView official trial listing → -
Active, not recruiting NCT NCT05366868
Durable Effect of Imeglimin on the Glycemic Control in Patients With Type 2 Diabetes Mellitus
Not yet reported National Center for Global Health and Medicine, Japan 567 participants Est. completion 2027-03-31 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT05367063
Canagliflozin and Myocardial Fibrosis
Not yet reported Shanghai Zhongshan Hospital 45 participants Est. completion 2025-03-20 1 siteType 2 diabetes Other conditions: Cardiovascular RiskView official trial listing → -
Completed NCT NCT05376969
Evaluate the Long Term Safety and Efficacy of DWP16001 add-on to Metformin in Patients With T2DM Inadequately Controlled on Metformin
Not yet reported Daewoong Pharmaceutical Co. LTD. 159 participants Est. completion 2022-05-16 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT05400863
Effect of NNS on Metformin/GDF15, Pilot
Not yet reported University of Florida 46 participants Est. completion 2024-08-02 1 siteOther conditions: Obesity, Adolescent, Pre DiabetesView official trial listing → -
Completed NCT NCT05413369
iGlarLixi vs IDegAsp in Chinese Participants After OAD(s)
Not yet reported Sanofi 582 participants Est. completion 2023-10-20 60 sitesType 2 diabetesView official trial listing → -
Status unknown NCT NCT05416580
Efficacy of Ursodeoxycholic Acid (UDCA) in Patients With Type 2 Diabetes
Not yet reported University of Banja Luka 60 participants Est. completion 2024-04 1 siteType 2 diabetesView official trial listing → -
Status unknown NCT NCT05429554
The Effect of Metformin and DPP4 Inhibitors on Cognition and Cardiovascular Protection in Type 2 Diabetic Patients
MTI University 60 participants Est. completion 2022-09 1 siteType 2 diabetesView official trial listing → -
Status unknown NCT NCT05440591
Effects of Dapagliflozin and Metformin on Vascular Function in Newly-Diagnosed Treatment-Naive Type 2 Diabetes
Not yet reported Tan Tock Seng Hospital 150 participants Est. completion 2023-05-10 1 site Stand-aloneOther conditions: DiabetesView official trial listing → -
Completed NCT NCT05451147
A Comparative Study of the Effect of Ayurvedic Drugs and Metformin in the Management of Diabetes Mellitus (Type II)
Not yet reported A & U Tibbia College Karol Bagh 48 participants Est. completion 2019-04-30 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT05504226
Clinical Efficacy and Safety Evaluation of Teneligliptin in Type 2 Diabetes Who Have Inadequate GlycemIc Control With Empaglyflozin 25 mg and Metformin
Not yet reported Handok Inc. 214 participants Est. completion 2024-06-18 1 siteType 2 diabetesView official trial listing → -
Status unknown NCT NCT05505994
The Efficacy and Safety of DWP16001 in Combination With Metformin in T2DM Patients Inadequately Controlled on Metformin
Not yet reported Daewoong Pharmaceutical Co. LTD. 340 participants Est. completion 2024-09 1 siteType 2 diabetes Other conditions: Diabetes Mellitus, Glucose Metabolism Disorders, Metabolic Disease, Endocrine System DiseasesView official trial listing → -
Completed NCT NCT05521633
Comparison of the Effects of Metformin and Pioglitazone on Liver Enzymes and Ultrasound Changes in Non-Diabetic Non-Alcoholic Fatty Liver
Not yet reported King Edward Medical University 96 participants Est. completion 2022-05-24 1 siteMASLDView official trial listing → -
Terminated NCT NCT05536037
Metformin for the Prevention of Oral Cancer in Patients With Oral Premalignant Lesions
Not yet reported Thomas Jefferson University 4 participants Est. completion 2024-03-16 1 site Stand-aloneOther conditions: Erythroplakia, Leukoplakia, Oral Cavity Carcinoma, Proliferative Verrucous LeukoplakiaView official trial listing → -
Status unknown NCT NCT05536193
Topical Metformin Emulgel VS Salicylic Acid Peeling in Treatment of Acne Vulgaris
Not yet reported Assiut University 34 participants Est. completion 2023-09-10 Stand-aloneOther conditions: Acne VulgarisView official trial listing → -
Status unknown NCT NCT05545800
Efficacy and Safety Of Different Regimens In Patients With Type 2 Diabetes Receiving Intensive Insulin Therapy
Not yet reported Xiangya Hospital of Central South University 78 participants Est. completion 2024-06-01 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT05549583
Comparative Bioavailability Study of Sitagliptin/Metformin 50 mg/1000 mg Tablets in Healthy Male and Female Volunteers
Not yet reported Galenicum Health 26 participants Est. completion 2018-04-25 1 site Stand-aloneType 2 diabetes Other conditions: BioequivalenceView official trial listing → -
Completed NCT NCT05550129
Study to Evaluate the Drug-drug Interactions Between Metformin and AMG 510 in Healthy Participants
Not yet reported Amgen 13 participants Est. completion 2019-11-25 1 siteOther conditions: Healthy VolunteersView official trial listing → -
Status unknown NCT NCT05580523
Aspirin Versus Metformin in Pregnancies at High Risk of Preterm Preeclampsia: a 3-arm Randomized Controlled Trial
Not yet reported Chinese University of Hong Kong 3000 participants Est. completion 2025-11-30 6 sites Stand-aloneOther conditions: PreeclampsiaView official trial listing → -
Completed NCT NCT05615467
A Study of Effect of LY3556050 on Metformin in Healthy Participants
Not yet reported Eli Lilly and Company 18 participants Est. completion 2022-12-27 1 siteOther conditions: HealthyView official trial listing → -
Completed NCT NCT05638893
Metformin as Adjuvant Therapy in Obese Knee Osteoarthritis Patients
Not yet reported, Not yet reported Tanta University 50 participants Est. completion 2022-04-15 1 siteOsteoarthritisView official trial listing → -
Status unknown NCT NCT05663736
Effect of Gemigliptin Versus Glimepiride on Cardiac Diastolic Function in Patients With Type 2 Diabetes
Not yet reported Seoul National University Bundang Hospital 80 participants Est. completion 2023-12-31 1 siteOther conditions: Ejection FractionView official trial listing → -
Completed NCT NCT05694221
Drug Drug Interaction (DDI) Between Supaglutide and Digoxin or Metformin
Not yet reported Shanghai Yinnuo Pharmaceutical Technology Co., Ltd. 34 participants Est. completion 2023-08-17 1 site Stand-aloneOther conditions: Healthy VolunteersView official trial listing → -
Status unknown NCT NCT05703984
A Study to Evaluate the Safety, PK of GC2129A in Healthy Volunteers Under Fasting Conditions
Not yet reported GC Biopharma Corp 50 participants Est. completion 2023-04-19 1 site Stand-aloneOther conditions: Healthy VolunteersView official trial listing → -
Status unknown NCT NCT05729386
A Study to Evaluate the Safety, PK of GC2129A in Healthy Volunteers Under Fed Conditions
Not yet reported GC Biopharma Corp 34 participants Est. completion 2023-04-17 1 site Stand-aloneOther conditions: Healthy VolunteersView official trial listing → -
Completed NCT NCT05741372
A Study to Compare How Different Medicines (Rosuvastatin, Digoxin, Metformin, and Furosemide) Are Handled by the Body of Healthy People and People With Liver Cirrhosis
Not yet reported Boehringer Ingelheim 28 participants Est. completion 2024-12-30 1 siteOther conditions: Liver CirrhosisView official trial listing → -
Active, not recruiting NCT NCT05743387
Community-based, eHealth Supported Type 2 Diabetes Care by Lay Village Health Workers in Rural Lesotho
Not yet reported University Hospital, Basel, Switzerland 252 participants Est. completion 2027-12-31 2 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT05753371
Bioequivalence Study of Metformin Hydrochloride 500 mg Film-Coated Tablets in Indonesia Healthy Subject
Not yet reported PT. Pyridam Farma Tbk 24 participants Est. completion 2022-03-31 1 siteOther conditions: Drug UseView official trial listing → -
Completed NCT NCT05801627
SAL067 Treatment in Patients With Type 2 Diabetes Who Are Not Controlled by Metformin
Not yet reported Shenzhen Salubris Pharmaceuticals Co., Ltd. 408 participants Est. completion 2022-05-24 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT05815680
A Study to Evaluate the Drug-drug Interactions (DDIs) of IBI362 With Metformin, Warfarin, Atorvastatin, Digoxin in Overweight or Obese Subjects
Not yet reported Innovent Biologics (Suzhou) Co. Ltd. 48 participants Est. completion 2023-10-30 1 site Stand-aloneOther conditions: Overweight Subjects, Obese SubjectsView official trial listing → -
Withdrawn NCT NCT05828303
A Phase 1 Study to Evaluate the Potential Drug Interactions Between Repotrectinib and Metformin, Digoxin, and Rosuvastatin in Patients With Advanced Solid Tumors
Not yet reported Turning Point Therapeutics, Inc. Est. completion 2025-11-30 33 sites Stand-aloneOther conditions: Advanced Solid Tumor, Metastatic Solid TumorView official trial listing → -
Completed NCT NCT05838573
Metformin Treatment on Cognitive Impairment of Schizophrenia
Not yet reported Central South University 120 participants Est. completion 2026-06-08 4 sitesOther conditions: SchizophreniaView official trial listing → -
Withdrawn NCT NCT05854966
CPI-613 Given With Metformin in Patients With Relapsed or Refractory Acute Myeloid Leukemia (AML)
Not yet reported Wake Forest University Health Sciences Est. completion 2025-09Other conditions: Acute Myeloid Leukemia, in Relapse, Acute Myeloid Leukemia Refractory, Granulocytic SarcomaView official trial listing → -
Completed NCT NCT05874180
A Pharmacokinetic Study of DW6013 (FDC of Linagliptin and Metformin) in Healthy Adult Volunteers in Fed Condition
Not yet reported Dong Wha Pharmaceutical Co. Ltd. 31 participants Est. completion 2023-02-03 1 siteOther conditions: Healthy SubjectsView official trial listing → -
Status unknown NCT NCT05878535
METFORMIN FOR ATRIAL FIBRILLATION
Not yet reported Arab Contractors Medical Centre 770 participants Est. completion 2025-04 1 siteOther conditions: Atrial FibrillationView official trial listing → -
Completed NCT NCT05900284
Safety and Feasibility of Metformin for Sepsis Induced AKI
Not yet reported Hernando Gomez 80 participants Est. completion 2026-05-18 1 siteOther conditions: Sepsis, Septic Shock, Acute Kidney Injury, MetforminView official trial listing → -
Completed NCT NCT05921942
The Impact of Metformin Administration on the Clinical Outcome of Stage IV Colon Cancer
Not yet reported Ain Shams University 70 participants Est. completion 2022-12-30 1 siteOther conditions: Colorectal CancerView official trial listing → -
Status unknown NCT NCT05942963
Efficacy of Empagliflozin and Pioglitazone in Diabetic Patients With NAFLD
Not yet reported Jinnah Postgraduate Medical Centre 240 participants Est. completion 2024-04 1 site Stand-aloneOther conditions: Non-Alcoholic Fatty Liver Disease, Type2diabetesView official trial listing → -
Status unknown NCT NCT05950516
Efficacy and Safety of Semaglutide Ingection in Subjects With Type 2 Diabetes
Not yet reported Qilu Pharmaceutical Co., Ltd. 478 participants Est. completion 2025-01-22 1 site Added to GLP-1Type 2 diabetesView official trial listing → -
Completed NCT NCT05965908
Effect of Liraglutide in Obese Women With Polycystic Ovary Syndrome
Not yet reported Beni-Suef University 183 participants Est. completion 2025-12-30 1 siteOther conditions: Polycystic OvaryView official trial listing → -
Active, not recruiting NCT NCT06005142
Therapeutic Intervention of Eriomin Associated with Metformin in the Control of Hyperglycemia in Pre-Diabetic Patients
Not yet reported Thais Cesar 80 participants Est. completion 2024-12-30 1 sitePrediabetesView official trial listing → -
Completed NCT NCT06015594
Metformin Treatment in Adolescent Patients With PCOS: A Long-term, Winning Metabolic Choice.
Not yet reported University of Cagliari 168 participants Est. completion 2022-05-01 Stand-aloneOther conditions: Polycystic Ovary SyndromeView official trial listing → -
Status unknown NCT NCT06031168
1% Metformin Gel-coated Implants and Osteointegration and Crestal Marginal Bone Loss
Not yet reported Hams Hamed Abdelrahman 26 participants Est. completion 2023-11-30 1 siteOther conditions: OsteointegrationView official trial listing → -
Status unknown NCT NCT06041399
The Effect of Related Blood Markers on Diabetic Peripheral Neuropathy
Not yet reported First Affiliated Hospital of Wenzhou Medical University 1400 participants Est. completion 2025-01-02 1 siteOther conditions: Diabetic Peripheral NeuropathyView official trial listing → -
Completed NCT NCT06045221
A Study of Orforglipron (LY3502970) Compared With Semaglutide in Participants With Type 2 Diabetes Inadequately Controlled With Metformin
Not yet reported Eli Lilly and Company 1698 participants Est. completion 2025-08-22 131 sitesType 2 diabetesView official trial listing → -
Status unknown NCT NCT06059287
The Effect of Henagliflozin and Metformin on Myocardial Tissue-level Characteristics
Not yet reported RenJi Hospital 64 participants Est. completion 2025-12-31Type 2 diabetes Other conditions: Obesity, Sodium-glucose Co-transporter-2 Inhibitor, Myocardial Fibrosis, Magnetic Resonance ImagingView official trial listing → -
Status unknown NCT NCT06064552
Screening For First Trimester's Hyperglycemia in High and Low Risk Pregnancy
Sohag University 100 participants Est. completion 2024-09-24 1 siteOther conditions: Screening for Hyperglycemia in First Trimester in High and Low Risk PregnancyView official trial listing → -
Completed NCT NCT06068686
Vildagliptin Versus Glimepiride in Type 2 Diabetic Patients
Not yet reported Damanhour University 70 participants Est. completion 2024-12-01 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT06073600
Bioequivalence Study to Compare Metformin / Vildagliptin Versus Galvumet®
Not yet reported Reseach Laboratory of Clinical and Experimental Pharmacology 18 participants Est. completion 2022-11-13 1 site Stand-aloneOther conditions: Fed ConditionsView official trial listing → -
Status unknown NCT NCT06080802
The Effect of Addition of Metformin to SGLT2 In Diabetic Patients With Heart Failure With Preserved Ejection Fraction
Not yet reported, Not yet reported October University for Modern Sciences and Arts 80 participants Est. completion 2024-12-01 1 site Stand-aloneHeart failure Other conditions: Diabete Type 2View official trial listing → -
Withdrawn NCT NCT06083675
Research Study to Compare Semaglutide Tablets With Empagliflozin or Metformin Tablets in People With Type 2 Diabetes
Not yet reported Novo Nordisk A/S Est. completion 2027-05-28 100 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT06084156
A Study to Evaluate the DDI of HSK7653 With Metformin
Not yet reported Haisco Pharmaceutical Group Co., Ltd. 22 participants Est. completion 2019-12-09 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT06101147
Effect of Vitamin D Supplementation on Testosterone Level in Women With Polycystic Ovary Syndrome
Not yet reported Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh 66 participants Est. completion 2024-07-30 1 siteOther conditions: PCOS, Vitamin DView official trial listing → -
Completed NCT NCT06109311
A Study of Orforglipron (LY3502970) in Participants With Type 2 Diabetes and Inadequate Glycemic Control With Insulin Glargine, With or Without Metformin and/or SGLT-2 Inhibitor
Not yet reported Eli Lilly and Company 546 participants Est. completion 2025-09-15 70 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT06125587
Chiglitazar/Metformin in Non-obese Women With PCOS
Not yet reported, Not yet reported Shengjing Hospital 55 participants Est. completion 2024-11-20 1 siteOther conditions: Polycystic Ovary Syndrome, Chiglitazar, MetforminView official trial listing → -
Status unknown NCT NCT06140485
A Trial to Investigate the Efficacy and Safety of NW Low-Glu® in Patients With Type II Diabetes Mellitus
Not yet reported Natural Wellness Egypt 400 participants Est. completion 2025-10Type 2 diabetesView official trial listing → -
Status unknown NCT NCT06181422
Metformin and Lactoferrin in Sepsis in Icu
Not yet reported, Not yet reported Tanta University 60 participants Est. completion 2024-06-09 1 siteOther conditions: SepsisView official trial listing → -
Status unknown NCT NCT06182618
Retrospective Analysis for Patients With Metabolic Syndrome
Second Affiliated Hospital, Zhejiang University, School of Medicine 400 participants Est. completion 2024-01-01 1 siteMetabolic syndromeView official trial listing → -
Status unknown NCT NCT06188234
The Prescription Patterns and Clinical Efficacy of Tenero Tab/Tenero M SR Tab
Hanlim Pharm. Co., Ltd. 3000 participants Est. completion 2026-06 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT06192108
A Study of Orforglipron (LY3502970) Compared With Dapagliflozin in Adult Participants With Type 2 Diabetes and Inadequate Glycemic Control With Metformin
Not yet reported Eli Lilly and Company 962 participants Est. completion 2025-09-26 74 sitesType 2 diabetesView official trial listing → -
Status unknown NCT NCT06199544
Effect of Unani Medicine for the Management of Anomalies Associated With Polycystic Ovarian Syndrome
Not yet reported Hamdard University 150 participants Est. completion 2024-12-01 1 siteOther conditions: Comparative StudyView official trial listing → -
Completed NCT NCT06204107
A Clinical Trial to Evaluate the Food Effect on Pharmacokinetic Profiles and Safety of CKD-379
Not yet reported Chong Kun Dang Pharmaceutical 28 participants Est. completion 2023-12-06 1 site Stand-aloneType 2 diabetesView official trial listing → -
Status unknown NCT NCT06217887
Efficacy Comparison of Polyethylene Glycol Loxenatide and Gliclazide on the Brain Function in T2DM Patients
Not yet reported The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School 58 participants Est. completion 2024-06 1 siteType 2 diabetes Other conditions: Cognitive Function AbnormalView official trial listing → -
Completed NCT NCT06221969
A Research Study to See How Much CagriSema Lowers Blood Sugar and Body Weight Compared to Tirzepatide in People With Type 2 Diabetes Treated With Metformin With or Without an SGLT2 Inhibitor
Not yet reported Novo Nordisk A/S 1024 participants Est. completion 2026-04-06 197 sitesType 2 diabetesView official trial listing → -
Status unknown NCT NCT06233201
Sitagliptin and Metformin Hydrochloride Tablets 50 mg/500 mg Relative to Originator
Not yet reported Bio-innova Co., Ltd 34 participants Est. completion 2024-07-28Other conditions: Healthy SubjectsView official trial listing → -
Completed NCT NCT06235086
A Study of TG103 Injection Combined With Metformin in Treatment of Type 2 Diabetes Mellitus
Not yet reported CSPC Baike (Shandong) Biopharmaceutical Co., Ltd. 632 participants Est. completion 2026-02-03 1 siteType 2 diabetesView official trial listing → -
Status unknown NCT NCT06243536
The Effect of Semaglutide on Disordered Eating Behaviour in Type 2 Diabetic Patients
Not yet reported University Hospital Sestre Milosrdnice 60 participants Est. completion 2024-12-31 1 siteType 2 diabetes Other conditions: Overweight, Disordered Eating BehaviorsView official trial listing → -
Completed NCT NCT06244550
Clinical Trials Using HepatoKeeper Herbal Essentials to Treat Non-alcoholic Fatty Liver Disease and Metabolic Factors
Not yet reported Taipei City Hospital 60 participants Est. completion 2023-06-13 1 siteOther conditions: Non-alcoholic Fatty Liver Disease, Liver Fibrosis, Liver InjuryView official trial listing → -
Completed NCT NCT06247748
Influence of JY09 on Pharmacokinetics of Metformin , Rosuvastatin , and Digoxin and the QT Interval Study in Overweight Chinese Subjects
Not yet reported Beijing Dongfang Biotech Co., Ltd. 28 participants Est. completion 2024-04-15 1 siteType 2 diabetes Other conditions: OverweightView official trial listing → -
Completed NCT NCT06280274
Metformin Use in Patients Undergoing Total Joint Replacement Surgery
Not yet reported Oregon Health and Science University 40 participants Est. completion 2025-09-15 1 site Stand-aloneOther conditions: HyperglycemiaView official trial listing → -
Terminated NCT NCT06296836
Effect of Continuing Versus Holding Metformin During Hospitalizations.
Not yet reported University of Illinois at Chicago 22 participants Est. completion 2026-04-30 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT06323161
A Research Study to See How Much CagriSema Lowers Blood Sugar and Body Weight Compared to Placebo in People With Type 2 Diabetes Treated With Once-daily Basal Insulin With or Without Metformin
Not yet reported Novo Nordisk A/S 274 participants Est. completion 2025-10-23 61 sitesType 2 diabetesView official trial listing → -
Terminated NCT NCT06333080
The Effect of Adherence to Oral Semaglutide on Glycaemic Control in People With Type 2 Diabetes Treated With Metformin
Aalborg University Hospital 1 participants Est. completion 2025-07-29 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT06335134
A Drug-Drug Interaction Study Between XW003 and Metformin, Warfarin, Rosuvastatin or Digoxin
Not yet reported Hangzhou Sciwind Biosciences Co., Ltd. 57 participants Est. completion 2024-06-28 1 siteOther conditions: Healthy VolunteersView official trial listing → -
Completed NCT NCT06357273
The Effect of White Tea Consumption on Obesity
Recep Tayyip Erdogan University 91 participants Est. completion 2023-12-15 1 siteOther conditions: Obesity, Obesity; Endocrine, Obesity Adult OnsetView official trial listing → -
Status unknown NCT NCT06405971
Metformin in Patients With Unruptured Vertebrobasilar Dissecting Aneurysms (METTLE)
Not yet reported Ming Lv 60 participants Est. completion 2025-06-01 1 siteOther conditions: Dissecting Aneurysm of Cerebral ArteryView official trial listing → -
Completed NCT NCT06416800
A Study to Assess the Effect of Povorcitinib on Digoxin, Rosuvastatin, and Metformin Pharmacokinetics and the Effect of Probenecid on Povorcitinib Pharmacokinetics When Administered Orally to Healthy Adult Participants
Not yet reported Incyte Corporation 71 participants Est. completion 2025-01-15 1 site Stand-aloneOther conditions: Healthy ParticipantsView official trial listing → -
Status unknown NCT NCT06439758
Effects of First-Line Oral Hypoglycemics in Bone Markers of Treatment Naïve Saudi Adults With Type 2 Diabetes
Not yet reported King Saud University 111 participants Est. completion 2025-12-01Other conditions: Diabetes Type 2, OsteoporosisView official trial listing → -
Status unknown NCT NCT06449235
Real-World Evaluation of Omarigliptin for Type 2 Diabetes Meliitus in Bangladesh
Not yet reported Bangladesh Institute of Research and Rehabilitation in Diabetes, Endocrine and Metabolic Disorders 938 participants Est. completion 2025-06 1 siteOther conditions: Type2diabetesView official trial listing → -
Not yet recruiting NCT NCT06460896
Analysis of the Influence of Gastric By-Pass on the Pharmacokinetics of Common Drugs
Not yet reported Assistance Publique - Hôpitaux de Paris 64 participants Est. completion 2027-09 1 siteOther conditions: Bypass Bariatric SurgeryView official trial listing → -
Completed NCT NCT06473662
Study to Evaluate the Safety and Efficacy of Oral Insulin Formulation in Type 2 Diabetes Mellitus Subjects
Not yet reported Roger New 153 participants Est. completion 2020-07-11 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT06479434
Serum Biomarker Levels Improvement in Poly Cystic Ovarian Syndrome: Impact of Metformin Compared to Healthy Controls
Not yet reported Aga Khan University 110 participants Est. completion 2025-10-02 1 siteOther conditions: Polycystic Ovary Syndrome, Insulin ResistanceView official trial listing → -
Status unknown NCT NCT06492655
To Evaluate the Food Effect on Pharmacokinetic Profiles and Safety in Healthy Volunteers
Not yet reported Chong Kun Dang Pharmaceutical 28 participants Est. completion 2024-08-08Type 2 diabetesView official trial listing → -
Completed NCT NCT06495931
Study on Drug Interaction of HRS-1780 Tablets, Henagliflozin Tablets, Metformin Tablets and HRS-7535 Tablets in Healthy Human
Not yet reported Shandong Suncadia Medicine Co., Ltd. 24 participants Est. completion 2024-08-13 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT06504862
A Study in Healthy Men to Test Whether Zongertinib Influences the Amount of 4 Other Medicines (Dabigatran, Rosuvastatin, Metformin, and Furosemide) in the Blood
Not yet reported Boehringer Ingelheim 32 participants Est. completion 2024-12-18 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Status unknown NCT NCT06515652
To Compare the Effects of Herbal Medicines With Traditional Allopathic Medicines in Cases of Patients With Metabolic Syndrome
Not yet reported Hamdard University 200 participants Est. completion 2024-08-30 1 siteMetabolic syndromeView official trial listing → -
Completed NCT NCT06523595
Evaluation of the Pharmacokinetic Drug-drug Interactions Between VX-993 and Metformin in Healthy Adults
Not yet reported Vertex Pharmaceuticals Incorporated 31 participants Est. completion 2024-12-31 1 site Stand-aloneOther conditions: PainView official trial listing → -
Withdrawn NCT NCT06526494
Metformin and Vascular Function in Prediabetes
Not yet reported Diana Jalal Est. completion 2025-12-01 2 sites Stand-alonePrediabetesView official trial listing → -
Status unknown NCT NCT06545994
A Prospective Cohort Study on the Serum Kisspeptin Levels Throughout Pregnancy in PCOS
Fudan University 180 participants Est. completion 2026-06-30 1 siteOther conditions: Polycystic Ovary Syndrome, Pregnancy ComplicationsView official trial listing → -
Status unknown NCT NCT06559722
A Trial Investigating the Efficacy and Safety of Insulin Degludec/Liraglutide Injection in Subjects With Type 2 Diabetes
Not yet reported Tonghua Dongbao Pharmaceutical Co.,Ltd 510 participants Est. completion 2026-02Type 2 diabetesView official trial listing → -
Status unknown NCT NCT06589141
Comparison Between Metformin and Glyburide in the Management of Gestational Diabetes
Not yet reported Assiut University 180 participants Est. completion 2026-06-30 Stand-aloneOther conditions: Gestational Diabetes Mellitus in PregnancyView official trial listing → -
Completed NCT NCT06628544
Trained Immunity in Fungal Infection and Its Mechanism
Not yet reported Zhongnan Hospital 79 participants Est. completion 2023-12-01 1 site Stand-aloneOther conditions: BCG VaccinationView official trial listing → -
Not yet recruiting NCT NCT06682351
Heterogeneity of Diabetes: Integrated Muli-Omics to Identify Physiologic Subphenotypes and Evaluate Targeted Prevention
Not yet reported Stanford University 200 participants Est. completion 2027-12 1 site Stand-aloneType 2 diabetesPrediabetesView official trial listing → -
Enrolling by invitation NCT NCT06683235
Effect of Flaxseed as a Treatment for Adults With Type 2 Diabetes Mellitus in Mexico
Not yet reported Universidad Autónoma Benito Juárez de Oaxaca 160 participants Est. completion 2025-03 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT06688123
Efficacy and Safety of SHR-3167 and Insulin Glargine in Type 2 Diabetes Subjects
Not yet reported Jiangsu HengRui Medicine Co., Ltd. 275 participants Est. completion 2026-04-22 2 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT06727838
Study on Drug Interaction of Metformin Tablets and HRS-7535 Tablets in Healthy Human
Not yet reported Shandong Suncadia Medicine Co., Ltd. 18 participants Est. completion 2025-01-25 1 site Stand-aloneOther conditions: DiabetesView official trial listing → -
Completed NCT NCT06728982
Impact Of Metformin In Rectal Cancer Patients
Not yet reported, Not yet reported Minia University 85 participants Est. completion 2025-07-15 2 sitesOther conditions: Rectal Cancer PatientsView official trial listing → -
Not yet recruiting NCT NCT06743698
META Trial - a Mixed Methods Process Evaluation
University College Dublin 60 participants Est. completion 2027-02Prediabetes Other conditions: HIVView official trial listing → -
Enrolling by invitation NCT NCT06773923
Effectiveness of 3D-printed Patient-specific Resorbable Scaffolds for Maxillary Bone Regeneration
Not yet reported Universidad Austral de Chile 10 participants Est. completion 2025-12-01 1 siteOther conditions: Bone Loss, Jaw, Edentulous, Edentulous Mouth, Jaw Fractures, Bone Loss, Age RelatedView official trial listing → -
Not yet recruiting NCT NCT06775093
Effects of GLP-1RAs on Reproductive Outcomes in PCOS and Obesity
Not yet reported Peking University Third Hospital 392 participants Est. completion 2027-12-31 1 siteOther conditions: Polycystic Ovary Syndrome, Obesity, Infertility, FemaleView official trial listing → -
Active, not recruiting NCT NCT06778967
A Phase III Clinical Study to Evaluate the Efficacy and Safety of GZR18 Injection in Adult Type 2 Diabetes Mellitus
Not yet reported Gan & Lee Pharmaceuticals. 1100 participants Est. completion 2026-12-11 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT06793943
A Study of Interaction of Zasocitinib (TAK-279) With Other Medicines in Healthy Adults
Not yet reported Takeda 78 participants Est. completion 2025-03-30 1 site Stand-aloneOther conditions: Healthy VolunteersView official trial listing → -
Not yet recruiting NCT NCT06840613
Glucophage Plus Myo-Inositol vs Glucophage in Glycemic Control Among Patients With Gestational Diabetes Mellitus
Not yet reported University of Health Sciences Lahore 90 participants Est. completion 2025-05Other conditions: Gestational Diabetes Mellitus (GDM)View official trial listing → -
Completed NCT NCT06871761
A Trial Comparing HR17031 With Insulin Glargine in Patients With Type 2 Diabetes
Not yet reported Jiangsu HengRui Medicine Co., Ltd. 393 participants Est. completion 2025-05-13 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT06871904
Fibrosis-Modulating Effects of Metformin and Pirfenidone in Oral Submucous Fibrosis
Not yet reported, Not yet reported Ziauddin University 45 participants Est. completion 2025-12-30 1 siteOther conditions: Oral Submucous FibrosisView official trial listing → -
Not yet recruiting NCT NCT06893978
Placental Organoids Development: Application in the Study of the Human Reproduction Pathophysiology.
Fondazione Policlinico Universitario Agostino Gemelli IRCCS 20 participants Est. completion 2027-11 1 siteOther conditions: Preeclampsia, Pregnancy Loss, Preterm Birth, HealthyView official trial listing → -
Active, not recruiting NCT NCT06899061
Modular Clinical Pharmacology Study to Evaluate the Drug-drug Interaction Potential and Relative Bioavailability of Saruparib
Not yet reported AstraZeneca 41 participants Est. completion 2028-05-19 4 sitesOther conditions: Advanced Solid MalignanciesView official trial listing → -
Active, not recruiting NCT NCT06907472
Diabetes Management for Primary Healthcare Centers.
Not yet reported University of Abuja 106 participants Est. completion 2026-12-31 2 sitesType 2 diabetesView official trial listing → -
Not yet recruiting NCT NCT06911983
Comparative Efficacy of Metformin and Berberine Among TCF7L2 (rs7903146) TT vs. CC Genotype Carriers With Type 2 Diabetes
Not yet reported S.LAB (SOLOWAYS) 60 participants Est. completion 2026-03-01 1 siteOther conditions: Diabetes MellitisView official trial listing → -
Completed NCT NCT06913881
Comparative Cardiovascular Effectiveness of GLP-1 RAs vs. Insulin in Early-Onset Type 2 Diabetes
Karolinska Institutet 92100 participants Est. completion 2025-01-31 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT06920056
A Study of BGM0504 in Overweight or Obese Participants
Not yet reported BrightGene Bio-Medical Technology Co., Ltd. 28 participants Est. completion 2025-07-25 1 site Stand-aloneOther conditions: Overweight or ObeseView official trial listing → -
Not yet recruiting NCT NCT06946628
New Triple Therapy in Newly Diagnosed Type 2 Diabetes
Not yet reported Sun Yat-sen University 296 participants Est. completion 2030-12-31 1 siteOther conditions: Diabetes MellitusView official trial listing → -
Not yet recruiting NCT NCT06975839
Local Metformin Gel and Impacted Lower Third Molar
Not yet reported Fayoum University 36 participants Est. completion 2026-02-01Other conditions: Impacted Third Molar ToothView official trial listing → -
Completed NCT NCT06983223
Oral Sucrosomial® Vitamin B12 in the Management of B12 Deficiency Among Metformin-Treated Type 2 Diabetes Patients
Not yet reported Liaquat University of Medical & Health Sciences 50 participants Est. completion 2025-12-03 1 siteType 2 diabetes Other conditions: Vitamin B 12 DeficiencyView official trial listing → -
Withdrawn NCT NCT07007221
Clinical Trials to Evaluate Metformin to Treat Depression in People Living With HIV
Not yet reported University of Minnesota Est. completion 2030-12-01Other conditions: Depression, HivView official trial listing → -
Not yet recruiting NCT NCT07027969
Metabolic Surgery for Atrial Fibrillation Elimination
Not yet reported Ali Aminian 100 participants Est. completion 2030-03-31 1 siteOther conditions: Atrial Fibrillation, Obesity and Obesity-related Medical ConditionsView official trial listing → -
Active, not recruiting NCT NCT07055958
Effect of Metformin as Add-on Therapy in Levodopa Treated Parkinson's Disease Patients
Not yet reported Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh 74 participants Est. completion 2025-07-20 1 siteOther conditions: Parkinson DiseaseView official trial listing → -
Completed NCT NCT07058675
Myoinositol vs. Metformin for Polycystic Ovarian Syndrome (PCOS): Impact on Metabolic Health and Fertility
Not yet reported Benha University 156 participants Est. completion 2025-06-18 1 siteOther conditions: PCOSView official trial listing → -
Completed NCT NCT07066722
A Study to Evaluate VH4524184 Tablet Absorption, Effects of Food, and Interactions With Other Drugs in Healthy Adults
Not yet reported ViiV Healthcare 126 participants Est. completion 2025-12-17 2 sites Stand-aloneOther conditions: HIV InfectionsView official trial listing → -
Enrolling by invitation NCT NCT07073768
Comparison Between Efficacy of Trelagliptin and Sitagliptin in Type II Diabetic Patients
Not yet reported Khyber Medical College, Peshawar 126 participants Est. completion 2026-12-30 1 site Stand-aloneType 2 diabetes Other conditions: Glycemic Control for Diabetes MellitusView official trial listing → -
Completed NCT NCT07077525
Effect of Vildagliptin Versus Dapagliflozin as Add on Therapy to Metformin on Cardiovascular Risk Factors
Not yet reported Al-Azhar University 196 participants Est. completion 2024-08-31 1 siteType 2 diabetesView official trial listing → -
Not yet recruiting NCT NCT07113756
New Topical Treatment in Plaque Psoriasis
Not yet reported Sohag University 70 participants Est. completion 2026-09-01Other conditions: Plaque PsoriasisView official trial listing → -
Completed NCT NCT07121959
A Study of Belzutifan (MK-6482) and Metformin in Healthy Adult Participants (MK-6482-039)
Not yet reported Merck Sharp & Dohme LLC 14 participants Est. completion 2025-09-26 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT07145827
Effect of Metformin on Endometrial Thickness in Postmenopausal Breast Cancer Patients Receiving Tamoxifen
Not yet reported Uruk University 60 participants Est. completion 2025-07-01 1 site Stand-aloneOther conditions: Breast Cancer, Endometrial Hyperplasia and Endometrial CancersView official trial listing → -
Completed NCT NCT07213895
Bioequivalence Study to Compare Empagliflozin/Linagliptin/Metformin HCL 25mg/5mg/1000mg Extended-Release Tablets Versus Trijardy® XR Extended Release Film Coated Tablets
Not yet reported Humanis Saglık Anonim Sirketi 14 participants Est. completion 2025-09-18 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT07216131
A Study to Investigate the Effect of AZD0780 on Metformin Pharmacokinetics in Healthy Adult Volunteers Aged 18 to 55 Years
Not yet reported AstraZeneca 14 participants Est. completion 2025-12-30 1 siteOther conditions: Healthy ParticipantsView official trial listing → -
Not yet recruiting NCT NCT07229534
Clinical Trial to Evaluate the Efficacy and Safety of DA-5218 in Patients With Type 2 Diabetes
Not yet reported Dong-A ST Co., Ltd. 238 participants Est. completion 2027-11Other conditions: Diabete MellitusView official trial listing → -
Not yet recruiting NCT NCT07241897
DPP4 Inhibitor Intervention on Post-stroke Cognitive Impairment in Ischemic Stroke Patients With Type 2 Diabetes
Not yet reported Second Affiliated Hospital of Soochow University 312 participants Est. completion 2028-04-30 1 site Stand-aloneCardiovascular disease Other conditions: Diabete MellitusView official trial listing → -
Active, not recruiting NCT NCT07279909
Phase-III Clinical Studies on Poly Herbal Anti-Diabetic Formulation
Not yet reported Hamdard University 500 participants Est. completion 2026-05-20 1 siteOther conditions: Diabetes Type 2, Diabetes Mellitus, Experimental, HbA1c, Urinary Glucose, Ability of Experimental Drug to Lower HbA1c Compare to MetforminView official trial listing → -
Not yet recruiting NCT NCT07300020
PK and Relative Bioavailability of Novel Liquid Metformin vs Tablets
Not yet reported Aspargo Labs, Inc 24 participants Est. completion 2026-06-28 Stand-aloneOther conditions: Healthy VolunteerView official trial listing → -
Not yet recruiting NCT NCT07300046
Tolerability Study of Liquid Metformin (100 and 250 mg/mL) vs IR Tablets
Not yet reported Aspargo Labs, Inc 24 participants Est. completion 2026-08-28Other conditions: Healthy VolunteersView official trial listing → -
Not yet recruiting NCT NCT07300059
Short-Term Glycemic Effects of Liquid Metformin vs Standard Tablets
Not yet reported Aspargo Labs, Inc 24 participants Est. completion 2026-08-28Other conditions: Healthy VolunteersView official trial listing → -
Completed NCT NCT07303127
Combination of Bitter Melon Extract and Snakehead Fish Powder to Reduce Glycaemia in Type 2 Diabetes Mellitus
Not yet reported Universitas Muhammadiyah Surakarta 80 participants Est. completion 2021-10-01 1 site Stand-aloneType 2 diabetesView official trial listing → -
Not yet recruiting NCT NCT07323381
Effects of Henagliflozin Proline and Metformin XR on Body Composition in Geriatric Patients With Newly Diagnosed T2DM
Not yet reported Bin Lu 116 participants Est. completion 2027-09-30Other conditions: Diabetes Type 2View official trial listing → -
Completed NCT NCT07323589
Impact of Myo-Inositol Alone vs Myo-Inositol Plus Metformin on Conception, Adherence, and Tolerability in PCOS
Not yet reported PAEC general hospital 120 participants Est. completion 2025-10-25 1 siteOther conditions: PCOS (Polycystic Ovary Syndrome)View official trial listing → -
Completed NCT NCT07333742
A Clinical Study to See How the Body Handles and How Safe a Combination Tablet of Gemigliptin, Dapagliflozin, and Metformin 50/10/1000mg is Compared to Taking Gemigliptin 50mg Separately With Dapagliflozin/Metformin 10/1000mg in Healthy Adults After a Meal
Not yet reported LG Chem 50 participants Est. completion 2025-11-27 1 siteOther conditions: Fed Conditions, Healthy VolunteerView official trial listing → -
Completed NCT NCT07336914
Effect of Conventional vs Intensive Management on Gestational Diabetes and Maternal Fetal Outcomes
Not yet reported Khyber Medical University Peshawar 60 participants Est. completion 2026-04-25 2 sites Stand-aloneOther conditions: Gestational DiabetesView official trial listing → -
Completed NCT NCT07363707
A Study Between Dapagliflozin and Empagliflozin Effect on NAFLD in Patients With Type 2 Diabetes.
Not yet reported Beni-Suef University 108 participants Est. completion 2024-03-01 1 siteMASLDView official trial listing → -
Not yet recruiting NCT NCT07395895
Effect of Metformin Iontophoresis on Knee Osteoarthritis in Postmenopausal Women
Not yet reported Badr University 68 participants Est. completion 2026-05-01 1 siteOsteoarthritisView official trial listing → -
Completed NCT NCT07396844
The Food Effect on Pharmacokinetics of Fixed Dose Combination of Gemigliptin/Dapagliflozin/Metformin in Healthy Volunteers
Not yet reported LG Chem 28 participants Est. completion 2026-06-26 1 siteOther conditions: Healthy, Fasting, FedView official trial listing → -
Completed NCT NCT07399470
A Clinical Study in Healthy Adults to See How the Body Processes and How Safe a Tablet That Combines Gemigliptin, Dapagliflozin, and Metformin is, Compared With Taking Zemiglo and Xigduo XR Together While Fasting.
Not yet reported LG Chem 58 participants Est. completion 2026-02-06 1 site Stand-aloneOther conditions: Healthy Volunteers, Fasting ConditionsView official trial listing → -
Not yet recruiting NCT NCT07417306
A Study of HDM1005 in Participants With T2DM Not Controlled With Metformin Alone or in Combination With a Sodium-Glucose Cotransporter 2 (SGLT2) Inhibitor
Not yet reported Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd. 912 participants Est. completion 2027-12-31 1 siteType 2 diabetesView official trial listing → -
Not yet recruiting NCT NCT07436182
Mitochondrial Redox Modulation in Newly Diagnosed Type 2 Diabetes: A Randomized Controlled Trial Comparing Imeglimin vs. Metformin Monotherapy
Not yet reported Mansoura University 176 participants Est. completion 2026-06-01 1 site Stand-aloneOther conditions: Mitochondria, MetforminView official trial listing → -
Completed NCT NCT07451938
A Cohort Study on Obese Patients' Multidisciplinary Integrated Health Management
China-Japan Friendship Hospital 1500 participants Est. completion 2025-07-30 1 siteOther conditions: Obesity, Diabete Type 2, Bariatric SurgeryView official trial listing → -
Completed NCT NCT07469254
Adding 1% Metformin Gel to Bone Graft in Association With Immediate Dental Implants
Not yet reported Al-Azhar University 20 participants Est. completion 2025-09-01 1 site Stand-aloneOther conditions: Metformin Gel, Bone Graft, Immediate Dental ImplantsView official trial listing → -
Active, not recruiting NCT NCT07475546
Combination Gerotherapeutic Interventions for Healthspan Improvement
Not yet reported AgelessRx 30 participants Est. completion 2026-04 1 site Stand-aloneOther conditions: Healthspan Improvement, Aging, LongevityView official trial listing → -
Completed NCT NCT07530289
A Clinical Study of Ulonivirine (MK-8507) With Atorvastatin and Metformin in Healthy Adults (MK-8507-018)
Not yet reported Merck Sharp & Dohme LLC 12 participants Est. completion 2026-06-03 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Not yet recruiting NCT NCT07536620
Metformin and Alveolar Cleft
Not yet reported Fayoum University 36 participants Est. completion 2027-05-30Other conditions: Alveolar CleftView official trial listing → -
Completed NCT NCT07541456
Empagliflozin Versus Non-SGLT2 Oral Drugs for Blood Pressure in Type 2 Diabetes
Not yet reported Dr. Zarmina Younes 300 participants Est. completion 2025-11-08 1 siteType 2 diabetes Other conditions: HypertensionView official trial listing → -
Completed NCT NCT07567781
A Phase 1 Study to Assess the Effect of ABBV-722 on Midazolam, Digoxin, Pitavastatin, Metformin, and Sitagliptin Drug Levels in Healthy Adults.
Not yet reported AbbVie 12 participants Est. completion 2026-07-21 1 site Stand-aloneOther conditions: Healthy VolunteersView official trial listing → -
Completed NCT NCT07585396
Inositol in Letrozol Resistant PCOS Women
Not yet reported, Not yet reported Kafrelsheikh University 136 participants Est. completion 2026-07-11 1 siteOther conditions: Polycystic Ovary Syndrome, InfertilityView official trial listing → -
Not yet recruiting NCT NCT07589387
Hypertension Treatment in Nigeria: Hypertension Diabetes Integration Study- Formative Aim 3
Not yet reported Washington University School of Medicine 2800 participants Est. completion 2030-01-31Other conditions: Diabete MellitusView official trial listing → -
Completed NCT NCT07604870
Krill Oil and Metformin in Women With PCOS and Metabolically Unhealthy Obesity
Not yet reported Firat University 54 participants Est. completion 2024-04-30 1 site Stand-aloneOther conditions: Polycystic Ovary Syndrome, Obesity, MetabolicView official trial listing → -
Completed NCT NCT07628556
Antidiabetic Medications and Risk of Cancer
University of Pecs 74799 participants Est. completion 2025-12-30 1 siteOther conditions: CancerView official trial listing → -
Completed NCT NCT07633015
Clinical Study to Determine Bioequivalence Between Two Oral Medications of Empagliflozin/Metformin in 5 mg / 850 mg Tablets Under Fed Conditions.
Not yet reported ADIUM 42 participants Est. completion 2025-04-29 1 siteOther conditions: Bioequivalence Study in Healthy SubjectsView official trial listing → -
Completed NCT NCT07633028
Clinical Study to Determine Bioequivalence Between Two Oral Medications of Empagliflozin/Metformin in 12.5 mg / 850 mg Tablets Under Fed Conditions.
Not yet reported ADIUM 42 participants Est. completion 2025-04-08 1 site Stand-aloneOther conditions: Bioequivalence Study in Healthy SubjectsView official trial listing → -
Completed NCT NCT07633054
Clinical Study to Determine Bioequivalence Between Two Oral Medications of Empagliflozin/Metformin in 12.5 mg / 500 mg Tablets Under Fed Conditions.
Not yet reported ADIUM 42 participants Est. completion 2025-11-24 1 siteOther conditions: Bioequivalence Study in Healthy SubjectsView official trial listing → -
Not yet recruiting NCT NCT07647003
A Study to Evaluate the Effect of Two Fixed-Dose Leucine, Sildenafil and Metformin Combinations on Blood Pressure in Individuals With Hypertension
Not yet reported NuSirt Biopharma 150 participants Est. completion 2027-07-07 Stand-aloneOther conditions: HypertensionView official trial listing → -
Completed NCT NCT07679711
Bioequivalence Study of Sitagliptin/Metformin Extended-Release Tablets in Healthy Subjects
Not yet reported The Affiliated Hospital of Qingdao University 76 participants Est. completion 2023-03-22 1 siteOther conditions: Healthy VolunteersView official trial listing → -
Not yet recruiting NCT NCT07687667
Effects of GLP-1RAs on Fertility Outcomes in Obese Women With PCOS
Not yet reported Peking University Third Hospital 406 participants Est. completion 2029-12 1 siteOther conditions: Polycystic Ovary Syndrome (PCOS), Obesity, Infertility, FemaleView official trial listing → -
Completed NCT NCT07694115
Bioequivalence Study to Compare Empagliflozin/ Metformin 25 mg/ 1000 mg Extended-Release Tablet Versus Synjardy XR Tablets 25mg/1000mg
Not yet reported Humanis Saglık Anonim Sirketi 40 participants Est. completion 2026-07-01 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT07702669
Modified Huanglian Wendan Decoction for Metabolic Syndrome
Not yet reported First Affiliated Hospital of Heilongjiang Chinese Medicine University 180 participants Est. completion 2025-08-31 1 site Stand-aloneMetabolic syndromeView official trial listing → -
Completed NCT NCT07763964
Clinical Study to Determine Bioequivalence Between Two Oral Medications of Sitagliptin/Metformin in Prolonged-release Tablets With 100 mg/1000 mg in Healthy Subjects, Fed Study.
Not yet reported ADIUM 46 participants Est. completion 2025-12-19 1 siteOther conditions: BioequivalanceView official trial listing → -
Not yet recruiting NCT NCT07768280
Efficacy and Safety of Hebenrun in Patients With Type 2 Diabetes
Not yet reported Jiangxi University of Traditional Chinese Medicine 110 participants Est. completion 2028-03 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT07770087
Effect of Metformin Gel on Guided Bone Regeneration Around Immediate Dental Implant at Posterior Maxillary Region
Not yet reported Al-Azhar University 12 participants Est. completion 2025-12-15 2 sites Stand-aloneOther conditions: Metformin Gel, Bone Healing, Guided Bone Regeneration, Crestal Bone Loss, Peri Implant Bone LossView official trial listing → -
Not yet recruiting NCT NCT07770711
Inositol and Metformin Administration in Mediterranean Diet and Low-Carbohydrate Diets in Women With PCOS
Not yet reported Dicle University 90 participants Est. completion 2027-06 1 siteOther conditions: PCOS (Polycystic Ovary Syndrome), Insulin Resistance, Obesity (BMI>30)View official trial listing → -
Completed NCT NCT07793838
Metformin Effects on Metabolic, Vitamin B12, Iron, Erythropoietin, and Hematological Parameters in Women With PCOS
Not yet reported Jerash Private University 400 participants Est. completion 2026-08-01 1 site Stand-aloneOther conditions: Polycystic Ovary Syndrome (PCOS) WomenView official trial listing → -
Not yet recruiting NCT NCT07796477
A Study of SYH2069 Injection in Participants With T2DM Not Controlled With Diet/Exercise Alone or Metformin
Not yet reported CSPC Ouyi Pharmaceutical Co., Ltd. 240 participants Est. completion 2027-10-19 1 siteType 2 diabetesView official trial listing →
Efficacy history
Not yet reported.
Safety
Not yet reported.
Sources
Related On The Pen coverage
No related coverage yet.
This drug may be investigational and not yet approved for any use. Whether someone can join a clinical trial is determined only by that trial's own study team — On The Pen does not determine eligibility. Information here can change; always confirm current details on the official ClinicalTrials.gov listing or with the sponsor.
