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About this data Sourced primarily from ClinicalTrials.gov — a listing isn't proof of safety or FDA approval.

Pipeline and clinical trial information here comes primarily from ClinicalTrials.gov. A listing on ClinicalTrials.gov means a study has been registered — not that a treatment is proven safe, effective, or FDA-approved. Investigational treatments may never be approved. Who can join a trial is decided only by that trial's own study team.

Not yet reported

MT-1186

Company
Shionogi
Mechanism
Mechanism not yet reported
Route
Route not yet reported
Recruiting trials
None currently listed

Efficacy results: Not yet reported

No recruiting studies currently listed

See all studies for this drug

Data source: ClinicalTrials.gov · trial data as of Sep 11, 2026

Trial details
  • Completed NCT NCT04165824

    Safety Study of Oral Edaravone Administered in Subjects With ALS

    Not yet reported Shionogi 185 participants Est. completion 2021-10-07 53 sites Stand-alone
    Other conditions: ALS
    View official trial listing →
  • Completed NCT NCT04176224

    Clinical Pharmacology Study of Oral Edaravone in Patients With Amyotrophic Lateral Sclerosis

    Not yet reported Shionogi 9 participants Est. completion 2019-09-04 1 site Stand-alone
    Other conditions: Japanese Patients With ALS
    View official trial listing →
  • Completed NCT NCT04254913

    Clinical Pharmacology Study of Oral Edaravone in Amyotrophic Lateral Sclerosis Patients With Gastrostomy

    Not yet reported Shionogi 6 participants Est. completion 2020-04-22 1 site Stand-alone
    Other conditions: Japanese Patients With ALS
    View official trial listing →
  • Completed NCT NCT04481750

    Study of Oral Edaravone in Healthy Adult Males

    Not yet reported Shionogi 74 participants Est. completion 2018-08-03 1 site Stand-alone
    Other conditions: Healthy Adult Subjects
    View official trial listing →
  • Completed NCT NCT04481789

    Clinical Pharmacology Study of Oral Edaravone in Healthy Adult Males (Drug Interaction Study and Preliminary Regimen-Finding Study)

    Not yet reported Shionogi 84 participants Est. completion 2019-01-08 1 site Stand-alone
    Other conditions: Healthy Adult Subjects
    View official trial listing →
  • Completed NCT NCT04493281

    Bioequivalence Study of Oral Suspension and Intravenous Formulation of Edaravone in Healthy Adult Subjects

    Not yet reported Shionogi 42 participants Est. completion 2019-05-09 1 site Stand-alone
    Other conditions: Healthy Adult Subjects
    View official trial listing →
  • Terminated NCT NCT04569084

    Efficacy and Safety Study of Oral Edaravone Administered in Subjects With ALS

    Not yet reported Shionogi 384 participants Est. completion 2023-09-29 95 sites Stand-alone
    Other conditions: ALS
    View official trial listing →
  • Completed NCT NCT04577404

    Safety Extension Study of Oral Edaravone Administered in Subjects With Amyotrophic Lateral Sclerosis (ALS)

    Not yet reported Shionogi 124 participants Est. completion 2023-08-09 44 sites Stand-alone
    Other conditions: Amyotrophic Lateral Sclerosis (ALS)
    View official trial listing →
  • Completed NCT NCT04776135

    Comparative Bioavailability Study of Oral Edaravone Administered Orally and Via a Nasogastric Tube

    Not yet reported Shionogi 36 participants Est. completion 2021-04-16 1 site Stand-alone
    Other conditions: Healthy Adult Subjects
    View official trial listing →
  • Terminated NCT NCT05151471

    Efficacy and Safety Extension Study of Oral Edaravone Administered in Subjects With ALS

    Not yet reported Shionogi 202 participants Est. completion 2023-09-29 37 sites Stand-alone
    Other conditions: ALS
    View official trial listing →
  • Completed NCT NCT05342597

    Clinical Pharmacology Study of Oral Edaravone in Healthy Adult Subjects (Food Effect Study)

    Not yet reported Shionogi 16 participants Est. completion 2019-07-24 1 site Stand-alone
    Other conditions: Healthy Adult Subjects
    View official trial listing →
  • Completed NCT NCT05568615

    Extension Study Following the Studies MT-1186-A03 or A04 to Evaluate the Safety of Oral Edaravone in Subjects With ALS

    Not yet reported Shionogi 15 participants Est. completion 2023-06-27 11 sites Stand-alone
    Other conditions: ALS
    View official trial listing →
Efficacy history

Not yet reported.

Safety

Not yet reported.

Sources
Related On The Pen coverage

No related coverage yet.

This drug may be investigational and not yet approved for any use. Whether someone can join a clinical trial is determined only by that trial's own study team — On The Pen does not determine eligibility. Information here can change; always confirm current details on the official ClinicalTrials.gov listing or with the sponsor.