About this data
Pipeline and clinical trial information here comes primarily from ClinicalTrials.gov. A listing on ClinicalTrials.gov means a study has been registered — not that a treatment is proven safe, effective, or FDA-approved. Investigational treatments may never be approved. Who can join a trial is decided only by that trial's own study team.
Sitagliptin
- Company
- Kafrelsheikh University
- Mechanism
- Mechanism not yet reported
- Route
- Route not yet reported
- Recruiting trials
- 11 recruiting
Efficacy results: Not yet reported
11 recruiting studies currently listed on ClinicalTrials.gov.
Data source: ClinicalTrials.gov · trial data as of Sep 11, 2026
Find a Clinical Trial Near Me
See recruiting studies for Sitagliptin and check eligibility with the study team.
Trial details
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Recruiting NCT NCT06246799
Comparative Effectiveness of Two Initial Combination Therapies in Patients With Recent Onset Diabetes
Not yet reported The University of Texas Health Science Center at San Antonio 256 participants Est. completion 2029-06-30 2 sitesType 2 diabetesView official trial listing → -
Recruiting NCT NCT06329882
Doxycycline in Type II Diabetes
Not yet reported, Not yet reported Mostafa Bahaa 60 participants Est. completion 2026-04-20 1 siteType 2 diabetesView official trial listing → -
Recruiting NCT NCT06587698
Sitagliptin or BeiDouGen Capsule Improve the Pregnancy Outcome in Patients with PCOS
Not yet reported Peking University Third Hospital 300 participants Est. completion 2029-07-01 1 siteOther conditions: Polycystic Ovarian SyndromeView official trial listing → -
Recruiting NCT NCT06875193
DM Treatment to Evaluate the Efficacy and Safety of Dapagliflozin or Pioglitazone in Patients with Type 2 Diabetes
Not yet reported Dong Wha Pharmaceutical Co. Ltd. 196 participants Est. completion 2025-12-31 1 site Stand-aloneOther conditions: Type2diabetesView official trial listing → -
Recruiting NCT NCT06972732
A Phase IV Clinical Trial to Compare the Efficacy and Safety of Metformin+Sodium-Glucose Cotransporter 2 Inhibitor(SGLT2-i)+Thiazolidinedione (TZD) in Patients With Type 2 Diabetes
Not yet reported Boryung Pharmaceutical Co., Ltd 204 participants Est. completion 2026-10-01 1 siteType 2 diabetesView official trial listing → -
Recruiting NCT NCT07003542
A Phase 2 and Pharmacodynamic Study of Sitagliptin in Patients With Progressive Grade 4 Gliomas
Not yet reported Case Comprehensive Cancer Center 48 participants Est. completion 2028-06 1 site Stand-aloneOther conditions: Glioblastoma, Brain TumorView official trial listing → -
Recruiting NCT NCT07374328
Triple Hypoglycemic Regimens In Patients With Newly Diagnosed Type 2 Diabetes Mellitus
Not yet reported, Not yet reported Second Affiliated Hospital of Guangzhou Medical University 240 participants Est. completion 2026-08-31 1 siteType 2 diabetesView official trial listing → -
Recruiting NCT NCT07541781
Sitagliptin in Recurrent/Progressive Grade 4 Glioma
Not yet reported Kailin Yang, MD, PhD 45 participants Est. completion 2030-06-11 1 site Stand-aloneOther conditions: Glioma, Glioblastoma, Recurrent Glioma, Recurrent Glioblastoma, Grade 4 Malignant Glioma of Brain (Disorder)View official trial listing → -
Recruiting NCT NCT07634380
Sitagliptin With Pembro in RCC and Melanoma
Not yet reported Fernando Maciel Barbosa 64 participants Est. completion 2031-04-10 1 site Stand-aloneOther conditions: Advanced Renal Cell Carcinoma, Advanced MelanomaView official trial listing → -
Recruiting NCT NCT07711171
Efficacy and Safety of Canagliflozin in the Treatment of Type 2 Diabetes With Mild Cognitive Impairment
Not yet reported Fudan University 60 participants Est. completion 2026-10-30 1 siteType 2 diabetes Other conditions: Cognitive ImpairmentView official trial listing → -
Recruiting NCT NCT07717242
Sun Yat-Sen Treatment Strategy for Enhancing Response in Muscle-invasive Bladder Cancer
Not yet reported Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University 80 participants Est. completion 2029-01-31 1 site Stand-aloneOther conditions: Bladder Urothelial Carcinoma, Bladder CancerView official trial listing → -
Completed NCT NCT00086502
Pioglitazone Add-on Study in Patients With Type 2 Diabetes Mellitus
Not yet reported Merck Sharp & Dohme LLC 353 participants Est. completion 2005-11Type 2 diabetesView official trial listing → -
Completed NCT NCT00086515
Metformin Add-on Study in Patients With Type 2 Diabetes Mellitus (0431-020)(COMPLETED)
Not yet reported Merck Sharp & Dohme LLC 701 participants Est. completion 2007-02-02Other conditions: Diabetes Mellitus, Type IIView official trial listing → -
Completed NCT NCT00087516
Monotherapy Study in Patients With Type 2 Diabetes Mellitus (0431-021)
Not yet reported Merck Sharp & Dohme LLC 741 participants Est. completion 2007-02Type 2 diabetesView official trial listing → -
Completed NCT NCT00094757
An Investigational Drug Study in Patients With Type 2 Diabetes Mellitus (MK0431-023)
Not yet reported Merck Sharp & Dohme LLC 521 participants Est. completion 2006-04-28Type 2 diabetesView official trial listing → -
Completed NCT NCT00094770
An Investigational Drug Study in Patients With Type 2 Diabetes Mellitus (0431-024)
Not yet reported Merck Sharp & Dohme LLC 1172 participants Est. completion 2007-05 Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00095056
An Investigational Drug in Patients With Type 2 Diabetes Mellitus and Chronic Renal Insufficiency (0431-028)(COMPLETED)
Not yet reported Merck Sharp & Dohme LLC 91 participants Est. completion 2006-07Type 2 diabetes Other conditions: Chronic Renal InsufficiencyView official trial listing → -
Completed NCT NCT00103857
MK0431 (Sitagliptin) and Metformin Co-Administration Factorial Study in Patients With Type 2 Diabetes Mellitus (0431-036)
Not yet reported Merck Sharp & Dohme LLC 1208 participants Est. completion 2008-02-21Type 2 diabetesView official trial listing → -
Completed NCT NCT00106704
Sulfonylurea Add-on Study in Patients With Type 2 Diabetes Mellitus (0431-035)
Not yet reported Merck Sharp & Dohme LLC 441 participants Est. completion 2007-01 Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00127192
A Study of an Investigational Drug Sitagliptin for Type 2 Diabetes Mellitus (0431-044)
Not yet reported Merck Sharp & Dohme LLC 363 participants Est. completion 2006-03 Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00289848
MK0431 Monotherapy Study in Patients With Type 2 Diabetes Mellitus (0431-040)
Not yet reported Merck Sharp & Dohme LLC 530 participants Est. completion 2007-03 Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00305604
Study of Sitagliptin in Older Type 2 Diabetics (0431-047)(COMPLETED)
Not yet reported Merck Sharp & Dohme LLC 206 participants Est. completion 2008-03-12Type 2 diabetesView official trial listing → -
Completed NCT NCT00337610
Sitagliptin Metformin Add-on Study in Patients With Type 2 Diabetes Mellitus
Not yet reported Merck Sharp & Dohme LLC 190 participants Est. completion 2007-08 Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00350779
Sitagliptin Metformin/PPARg Agonist Combination Therapy Add-on (0431-052)
Not yet reported Merck Sharp & Dohme LLC 262 participants Est. completion 2008-06-11 Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00363519
Controlled Study of MK-0431/ONO-5435 in Patients With Type 2 Diabetes Mellitus
Not yet reported Ono Pharmaceutical Co., Ltd. 195 participants 8 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00363844
Controlled Study of MK-0431/ONO-5435 in Patients With Type 2 Diabetes Mellitus
Not yet reported Ono Pharmaceutical Co., Ltd. 209 participants 8 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT00363948
Controlled Study of MK-0431/ONO-5435 in Patients With Type 2 Diabetes Mellitus
Not yet reported Ono Pharmaceutical Co., Ltd. 188 participants 8 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00364377
Incretins in Impaired Fasting Glucose
Not yet reported Mayo Clinic 22 participants Est. completion 2008-12 1 sitePrediabetesView official trial listing → -
Completed NCT NCT00371007
MK-0431 Early Phase II Double-blind Study - Type 2 Diabetes Mellitus (0431-043)
Not yet reported Merck Sharp & Dohme LLC 126 participants Est. completion 2005-04-25Type 2 diabetesView official trial listing → -
Completed NCT NCT00372060
MK0431 (Sitagliptin) Pioglitazone Add-on Study for Patients With Type 2 Diabetes Mellitus (0431-055)(COMPLETED)
Not yet reported Merck Sharp & Dohme LLC 134 participants Est. completion 2008-02-05 Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00395343
Sitagliptin Added-on to Insulin Study (0431-051)
Not yet reported Merck Sharp & Dohme LLC 641 participants Est. completion 2008-10-13 Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00397631
Initial Combination With Pioglitazone Study (0431-064)
Not yet reported Merck Sharp & Dohme LLC 520 participants Est. completion 2008-06-28Type 2 diabetesView official trial listing → -
Completed NCT NCT00411411
Long Term Effects of DPP-IV Inhibitor Treatment in Patients With Type 2 Diabetes
Not yet reported University Hospital, Gentofte, Copenhagen 49 participants Est. completion 2009-03 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT00411554
A Study of Sitagliptin in Patients With Type 2 Diabetes Mellitus Who Have Inadequate Glycemic Control on Diet/Exercise Therapy (0431-054)(COMPLETED)
Not yet reported Merck Sharp & Dohme LLC 319 participants Est. completion 2007-08 Stand-aloneOther conditions: Diabetes Mellitus, Non-Insulin-DependentView official trial listing → -
Completed NCT NCT00418366
A Study on the Effect of Kidney Disease on a Diabetes Medication (0431-008)
Not yet reported Merck Sharp & Dohme LLC 24 participants Est. completion 2003-03Other conditions: Renal Insufficiency, HemodialysisView official trial listing → -
Completed NCT NCT00420511
Beta-Cell Function and Sitagliptin Trial (BEST)
Not yet reported Samuel Lunenfeld Research Institute, Mount Sinai Hospital 21 participants Est. completion 2009-09 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00425490
Effect of Januvia on Beta Cell Function in Patients With Diabetes Mellitus
Not yet reported Sheba Medical Center 30 participants Est. completion 2009-07 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT00449930
Sitagliptin Comparative Study in Patients With Type 2 Diabetes (0431-049)
Not yet reported Merck Sharp & Dohme LLC 1050 participants Est. completion 2008-07-25 Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00451113
Sitagliptin in the Elderly
Not yet reported University of British Columbia 12 participants Est. completion 2012-11 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT00466518
Sitagliptin Treatment in Patients With Type 2 DM After Kidney Transplant
Not yet reported University of Oklahoma 16 participants Est. completion 2011-01 1 site Stand-aloneType 2 diabetes Other conditions: Kidney TransplantView official trial listing → -
Completed NCT NCT00477581
A Study to Compare the Effects of Exenatide and Sitagliptin on Postprandial Glucose in Subjects With Type 2 Diabetes Mellitus
Not yet reported AstraZeneca 102 participants Est. completion 2007-09 19 sites Added to GLP-1Type 2 diabetesView official trial listing → -
Completed NCT NCT00481663
A Study of Different Doses of Sitagliptin (MK-0431) in Participants With Type 2 Diabetes Mellitus (MK-0431-014)
Not yet reported Merck Sharp & Dohme LLC 555 participants Est. completion 2006-05-14 Stand-aloneOther conditions: Type II Diabetes MellitusView official trial listing → -
Completed NCT NCT00482079
A Study of MK0431 in Patients With Type 2 Diabetes (0431-010)
Not yet reported Merck Sharp & Dohme LLC 743 participants Est. completion 2006-06-15Other conditions: Diabetes Mellitus, Type IIView official trial listing → -
Completed NCT NCT00482729
MK0431A Comparative Study in Patients With Type 2 Diabetes (0431A-079)(COMPLETED)
Not yet reported Merck Sharp & Dohme LLC 1246 participants Est. completion 2009-04-27 Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00484419
Effects of Colesevelam HCl, Rosiglitazone, Sitagliptin on Control of Blood Glucose and Lipids in Type 2 Diabetes Patients Whose Blood Glucose Isn't Completely Controlled With Metformin
Not yet reported Daiichi Sankyo 169 participants Est. completion 2008-04 20 sitesType 2 diabetes Other conditions: HyperlipidemiaView official trial listing → -
Completed NCT NCT00501657
Effects of Sitagliptin on Gastric Emptying in Healthy Subjects
Not yet reported Royal Adelaide Hospital 15 participants Est. completion 2011-12 1 site Stand-aloneOther conditions: Gastroparesis, Diabetes MellitusView official trial listing → -
Completed NCT NCT00509236
Sitagliptin Versus Glipizide in Participants With Type 2 Diabetes Mellitus and End-Stage Renal Disease (MK-0431-073 AM1)
Not yet reported Merck Sharp & Dohme LLC 129 participants Est. completion 2011-03-14 Stand-aloneType 2 diabetes Other conditions: End-Stage Kidney DiseaseView official trial listing → -
Completed NCT NCT00509262
Sitagliptin Versus Glipizide in Participants With Type 2 Diabetes Mellitus and Chronic Renal Insufficiency (MK-0431-063 AM1)
Not yet reported Merck Sharp & Dohme LLC 426 participants Est. completion 2011-03-16 Stand-aloneType 2 diabetes Other conditions: Renal Insufficiency, ChronicView official trial listing → -
Completed NCT NCT00511108
Sitagliptin and Pioglitazone Mechanism of Action Study in Type 2 Diabetes Mellitus (0431-061)
Not yet reported Merck Sharp & Dohme LLC 211 participants Est. completion 2009-02-24 Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00532935
MK0431A vs. Pioglitazone in Patients With Type 2 Diabetes Mellitus (0431A-066)
Not yet reported Merck Sharp & Dohme LLC 517 participants Est. completion 2009-10-23 Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00541229
Sitagliptin Dose Comparison Study in Patients With Type 2 Diabetes (MK-0431-077)(COMPLETED)
Not yet reported Merck Sharp & Dohme LLC 103 participants Est. completion 2008-07-01 Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00541450
A Study to Evaluate the Efficacy and Safety of Sitagliptin and MK0431A in Comparison to a Commonly Used Medication in Patients With Type 2 Diabetes (0431-068)(COMPLETED)
Not yet reported Merck Sharp & Dohme LLC 492 participants Est. completion 2010-01-16 Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00541775
Safety/Efficacy of Sitagliptin in Patient w/ Type 2 Diabetes (0431-801)
Not yet reported Merck Sharp & Dohme LLC 273 participants Est. completion 2007-03 Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00545584
Addition Of Januvia (Sitagliptin) Improves Glycemic Control In Patients Inadequately Controlled By Metformin (MK0431-078)
Not yet reported Merck Sharp & Dohme LLC 1512 participants Est. completion 2009-11-19 Stand-aloneOther conditions: Diabetes Mellitus, Non-Insulin-DependentView official trial listing → -
Completed NCT NCT00551590
Effect of Sitagliptin on Incretin Effect in Patients With Type 2 Diabetes Mellitus
Not yet reported Ludwig-Maximilians - University of Munich 24 participants Est. completion 2011-09 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00616811
Safety and Tolerability of Vildagliptin Versus Sitagliptin in Patients With Type 2 Diabetes and Severe Renal Insufficiency
Not yet reported Novartis 148 participants Est. completion 2010-10 79 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT00627744
Beta-cell Function in Glucose Abnormalities and Acute Myocardial Infarction
Not yet reported Karolinska Institutet 85 participants Est. completion 2010-11 2 sitesCardiovascular diseasePrediabetes Other conditions: Unstable Angina Pectoris, Diabetes MellitusView official trial listing → -
Completed NCT NCT00631488
A Study to Test the Effectiveness and Safety of MK0893 in Combination With Other Drugs Used to Treat Type 2 Diabetes (0893-015)
Not yet reported Merck Sharp & Dohme LLC 146 participants Est. completion 2009-01 Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00637273
A Study to Compare the Glycemic Effects, Safety, and Tolerability of Exenatide Once Weekly to Those of Sitagliptin and Pioglitazone,in Subjects With Type 2 Diabetes Treated With Metformin (DURATION - 2)
Not yet reported AstraZeneca 514 participants Est. completion 2009-07 62 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT00642278
An Efficacy, Safety, and Tolerability Study of Canagliflozin (JNJ-28431754) in Patients With Type 2 Diabetes
Not yet reported Johnson & Johnson Pharmaceutical Research & Development, L.L.C. 451 participants Est. completion 2009-01 78 sitesOther conditions: Diabetes Mellitus, Type II, Diabetes Mellitus, Non Insulin DependentView official trial listing → -
Completed NCT NCT00642798
An Open-Label, Single- & Multiple-Dose Study to Investigate the Pharmacokinetics of Sitagliptin 100 mg in Healthy Chinese Adult Subjects (0431-108)(COMPLETED)
Not yet reported Merck Sharp & Dohme LLC 16 participants Est. completion 2008-03Other conditions: Diabetes Mellitus Non-insulin-dependentView official trial listing → -
Completed NCT NCT00650143
Sitagliptin Plus Granulocyte-colony Stimulating Factor in Acute Myocardial Infarction
Not yet reported, Not yet reported Ludwig-Maximilians - University of Munich 174 participants Est. completion 2013-06 1 siteCardiovascular diseaseView official trial listing → -
Completed NCT NCT00657280
Study of the Effect of Sitagliptin on Glucose (Sugar) Metabolism in Patients With Heart Failure
Not yet reported Stanford University 16 participants Est. completion 2012-02 1 site Stand-aloneHeart failureView official trial listing → -
Completed NCT NCT00659711
The Effect of Januvia (Sitagliptin) on Oxidative Stress in Obese Type 2 Diabetic Subjects
Not yet reported University at Buffalo 22 participants Est. completion 2013-12 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT00660075
Effects of Sitagliptin on Postprandial Lipemia in Men With Type 2 Diabetes
Not yet reported Laval University 36 participants Est. completion 2009-04 1 site Stand-aloneOther conditions: Diabetes Mellitus, Postprandial LipemiaView official trial listing → -
Completed NCT NCT00666458
18-week add-on to Metformin Comparison of Saxagliptin and Sitagliptin in Adult Patients With Type 2 Diabetes (T2D)
Not yet reported AstraZeneca 822 participants Est. completion 2009-03 87 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT00666848
Effect of Sitagliptin and an ACE Inhibitor on Blood Pressure in Metabolic Syndrome
Not yet reported Vanderbilt University 24 participants Est. completion 2010-01 1 siteMetabolic syndrome Other conditions: HypertensionView official trial listing → -
Completed NCT NCT00673894
Effects of Glutamine on GLP-1 and Insulin Secretion in Man
Not yet reported Garvan Institute of Medical Research 22 participants Est. completion 2014-11 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00676338
Safety and Efficacy of Exenatide Once Weekly Injection Versus Metformin, Dipeptidyl Peptidase-4 Inhibitor, or Thiazolidinedione as Monotherapy in Drug-Naive Patients With Type 2 Diabetes (DURATION-4)
Not yet reported AstraZeneca 820 participants Est. completion 2011-01 106 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT00683735
Quantification of the Dipeptidyl Peptidase (DPP)-4 Inhibition-mediated Enhancement of the Activity of the Entero-insular Axis
Not yet reported, Not yet reported Michael A. Nauck 20 participants Est. completion 2013-12 1 siteOther conditions: DiabetesView official trial listing → -
Status unknown NCT NCT00684528
A Double-Blind, Randomized, Active-Comparator (Metformin) Controlled, Clinical Trial to Study the Efficacy and Safety of the Strategy to Start Patients With Type 2 Diabetes Mellitus on Janumet™ Compared to Metformin
Not yet reported Meir Medical Center 1000 participants Est. completion 2012-12 1 siteOther conditions: Diabetes Type 2View official trial listing → -
Completed NCT NCT00686634
Sitagliptin in Combination With Metformin and Sulfonylurea
Not yet reported Charles Drew University of Medicine and Science 108 participants Est. completion 2010-03 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00696826
A Study of MK0431 in Patients WIth Hepatic Insufficiency (0431-017)(COMPLETED)
Not yet reported Merck Sharp & Dohme LLC 20 participants Est. completion 2004-05Other conditions: Liver InsufficiencyView official trial listing → -
Status unknown NCT NCT00696982
The Effect of Sitagliptin on Hypertension, Arterial Stiffness, Oxidative Stress and Inflammation
Not yet reported Assaf-Harofeh Medical Center 60 participants Est. completion 2009-06 1 site Stand-aloneOther conditions: Diabetes Mellitus, Arterial StiffnessView official trial listing → -
Status unknown NCT NCT00699322
Effect of Dipeptidyl Peptidase-IV Inhibitor and Sulfonylurea on Glucose Variability and Oxidative Stress
Not yet reported The Catholic University of Korea 36 participants Est. completion 2010-06 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00700817
The Effect of Liraglutide Compared to Sitagliptin, Both in Combination With Metformin on Glycaemic Control in Subjects With Type 2 Diabetes Mellitus
Not yet reported Novo Nordisk A/S 665 participants Est. completion 2010-06 166 sites Added to GLP-1Type 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT00701090
A Study to Test the Safety and Efficacy of Sitagliptin Compared to Glimepiride in Patients With Type 2 Diabetes on a Stable Dose of Metformin (0431-803)(COMPLETED)
Not yet reported Merck Sharp & Dohme LLC 1035 participants Est. completion 2009-10 Stand-aloneType 2 diabetes Other conditions: Diabetes Mellitus, Non-Insulin-DependentView official trial listing → -
Completed NCT NCT00704132
Sitagliptin Mechanism of Action Study in Patients With Type 2 Diabetes Mellitus (0431-059)
Not yet reported Merck Sharp & Dohme LLC 57 participants Est. completion 2010-04-28 Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00716092
The Effect of Linagliptin (BI 1356) on 24h-glucose Control and Various Biomarkers in Type 2 Diabetic Patients
Not yet reported Boehringer Ingelheim 121 participants 3 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00721552
Sitagliptin Prophylaxis for Glucocorticoid-Induced Impairment of Glucose Metabolism in Males With the Metabolic Syndrome
Not yet reported Amsterdam UMC, location VUmc 82 participants Est. completion 2012-06 1 siteOther conditions: Diabetes Mellitus, Steroid Diabetes, Glucocorticoid-induced Diabetes, Beta-cell FunctionView official trial listing → -
Completed NCT NCT00722371
MK0431 and Pioglitazone Co-Administration Factorial Study in Patients With Type 2 Diabetes Mellitus (0431-102 AM2)
Not yet reported Merck Sharp & Dohme LLC 1615 participants Est. completion 2011-03-25 Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00729326
Comparison of the Effect of Exenatide Versus Sitagliptin on 24-hour Average Glucose in Patients With Type 2 Diabetes on Metformin or a Thiazolidinedione
Not yet reported AstraZeneca 83 participants Est. completion 2009-10 1 site Added to GLP-1Type 2 diabetesView official trial listing → -
Completed NCT NCT00730275
A Study to Assess the Pharmacokinetics, Safety and Tolerability of Sitagliptin in Adolescents (0431-081)
Not yet reported Merck Sharp & Dohme LLC 35 participants Est. completion 2011-02-14 Stand-aloneType 2 diabetesView official trial listing → -
Status unknown NCT NCT00732121
Bone Turnover in Type 2 Diabetes Patients
Not yet reported University of Vermont 20 participants Est. completion 2010-08 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT00734474
A Study of LY2189265 Compared to Sitagliptin in Participants With Type 2 Diabetes Mellitus on Metformin
Not yet reported, Not yet reported Eli Lilly and Company 1202 participants Est. completion 2012-07 99 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT00740363
Sitagliptin in Renal Transplant Recipients
Not yet reported University of Oslo School of Pharmacy 25 participants Est. completion 2012-06 1 site Stand-aloneOther conditions: Glucose IntoleranceView official trial listing → -
Completed NCT NCT00747383
How Improvement in Control of Diabetes Influences the Production of a Hormone Produced in the Gut Which Improves the Release and Action of Insulin.
Not yet reported The Royal Bournemouth Hospital 74 participants Est. completion 2010-09 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT00749190
BI 10773 add-on to Metformin in Patients With Type 2 Diabetes
Not yet reported Boehringer Ingelheim 495 participants 116 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT00751114
Evaluation of Insulin Glargine Versus Sitagliptin in Insulin-naive Patients
Not yet reported Sanofi 515 participants Est. completion 2011-07 17 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT00754988
A Study of Taspoglutide Versus Sitagliptin for the Treatment of Patients With Type 2 Diabetes Mellitus Inadequately Controlled With Metformin.
Not yet reported Hoffmann-La Roche 666 participants Est. completion 2011-03 148 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00758069
Clinical Study on Sitagliptin for Assessment of Glucose-lowering Effects (0431-045)
Not yet reported Merck Sharp & Dohme LLC 80 participants Est. completion 2006-02-13 Stand-aloneOther conditions: Diabetes Mellitus, Non-Insulin-DependentView official trial listing → -
Completed NCT NCT00760344
Efficacy and Safety of SYR-472 in Subjects With Type 2 Diabetes Mellitus
Not yet reported Takeda 386 participants Est. completion 2008-03 112 sitesOther conditions: Diabetes MellitusView official trial listing → -
Terminated NCT NCT00766441
Sitagliptin Versus Sulphonylurea in Type 2 Diabetes During Ramadan
Not yet reported University of Manchester 22 participants Est. completion 2009-10 1 siteOther conditions: Diabetes, HypoglycemiaView official trial listing → -
Completed NCT NCT00768651
Incretin Effect and Use After Clinical Islet Transplantation
Not yet reported University of Alberta 8 participants Est. completion 2011-12 1 site Stand-aloneOther conditions: Type 1 DiabetesView official trial listing → -
Completed NCT NCT00770081
Safety and Tolerability of Vildagliptin Versus Sitagliptin in Patients With Type 2 Diabetes and Severe Renal Insufficiency (28-week Extension Study)
Not yet reported Novartis 75 participants Est. completion 2011-04 87 sitesType 2 diabetes Other conditions: Renal InsufficiencyView official trial listing → -
Completed NCT NCT00775684
Effect of Exenatide, Sitagliptin or Glimepiride on Functional ß -Cell Mass
Not yet reported University of Pennsylvania 47 participants Est. completion 2012-11 3 sites Stand-alonePrediabetesType 2 diabetesView official trial listing → -
Completed NCT NCT00780715
Response To Oral Agents in Diabetes (ROAD)- Pilot Study
Not yet reported University of Dundee 29 participants Est. completion 2009-10 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT00789191
Effect of Detemir and Sitagliptin on Blood Glucose Control in Type 2 Diabetes
Not yet reported Novo Nordisk A/S 222 participants Est. completion 2009-08 51 sites Stand-aloneType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT00790205
Sitagliptin Cardiovascular Outcomes Study (MK-0431-082)
Not yet reported Merck Sharp & Dohme LLC 14671 participants Est. completion 2015-03-30 Stand-aloneType 2 diabetesView official trial listing → -
Status unknown NCT NCT00790348
Effect of Januvia on Ghrelin and Other Gut Hormones in Patients With Diabetes
Wayne State University 45 participants 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT00795275
Incretin Effect in People With Impaired Fasting Glucose
Not yet reported University of Colorado, Denver 26 participants Est. completion 2008-11 1 site Stand-aloneOther conditions: ObesityView official trial listing → -
Completed NCT NCT00806520
Use of Continuous Glucose Monitoring Combined With Ambulatory Glucose Profiles to Characterize Glycemic Control
HealthPartners Institute 16 participants Est. completion 2011-08 5 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT00813228
Assessment of the Effects of a DPP-4 Inhibitor (Sitagliptin) Januvia on Immune Function in Healthy Individuals
Not yet reported National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) 76 participants Est. completion 2019-11-26 1 siteType 2 diabetes Other conditions: Diabetes Mellitus Type 1View official trial listing → -
Completed NCT NCT00813995
A Study to Test the Safety and Efficacy of Adding Sitagliptin in Patients With Type 2 Diabetes Mellitus (MK0431-074)
Not yet reported Merck Sharp & Dohme LLC 395 participants Est. completion 2010-08-09 Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00820573
Mechanisms of Glucose Lowering Effects of Sitagliptin and Metformin Alone and in Combination in Patients With T2DM
Not yet reported The University of Texas Health Science Center at San Antonio 16 participants Est. completion 2012-10 1 site Stand-aloneOther conditions: DiabetesView official trial listing → -
Completed NCT NCT00830076
A Study of the Effects of Co-Administration of Sitagliptin (MK-0431) and Metformin on Incretin Hormone Concentrations (MK-0431-110)
Not yet reported Merck Sharp & Dohme LLC 18 participants Est. completion 2009-05-14 Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00832390
Study to Assess the Efficacy and Safety of Sitagliptin in Recently Diagnosed, Naive Type 2 Diabetics With Inadequate Glycemic Control on Diet and Exercise (0431-158)
Not yet reported Merck Sharp & Dohme LLC 29 participants Est. completion 2008-07-11 Stand-aloneOther conditions: Diabetes MellitusView official trial listing → -
Terminated NCT NCT00832624
The Effect of Sitagliptin in Type 2 Diabetes Mellitus With Inadequate Glycemic Control (MK0431-118)
Not yet reported Merck Sharp & Dohme LLC 10 participants Est. completion 2009-09-02 Stand-aloneOther conditions: Diabetes Mellitus Non-insulin-dependentView official trial listing → -
Completed NCT NCT00833027
ALPHA Sitagliptin Add on to Metformin (0431-103)
Not yet reported Merck Sharp & Dohme LLC 608 participants Est. completion 2009-10-30 Stand-aloneOther conditions: Diabetes MellitusView official trial listing → -
Completed NCT NCT00837577
MK0431/ONO-5435 Phase III Clinical Trial -Add-on to Voglibose Study for Patients With Type 2 Diabetes Mellitus (MK0431-104)
Not yet reported Merck Sharp & Dohme LLC 133 participants Est. completion 2010-08-11 Stand-aloneOther conditions: Diabetes Mellitus, Non-Insulin-DependentView official trial listing → -
Terminated NCT NCT00837759
Novel Therapy to Preserve Beta Cell Function in New Onset Type 1 Diabetes
Not yet reported National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) 7 participants Est. completion 2011-03 1 siteOther conditions: Diabetes Mellitus Type 1, Autoimmune DiabetesView official trial listing → -
Completed NCT NCT00838903
Efficacy and Safety of Albiglutide in Treatment of Type 2 Diabetes
Not yet reported GlaxoSmithKline 1049 participants Est. completion 2013-04 386 sites Added to GLP-1Type 2 diabetesView official trial listing → -
Completed NCT NCT00842400
A Drug Interaction Study of VI-0521 With Metformin, Sitagliptan and Probenecid in Healthy Subjects.
Not yet reported VIVUS LLC 20 participants Est. completion 2009-04 1 siteOther conditions: ObesityView official trial listing → -
Completed NCT NCT00842556
Pharmacokinetic Drug Interaction Study of Dapagliflozin and Glimepiride or Sitagliptin in Healthy Subjects
Not yet reported AstraZeneca 18 participants Est. completion 2009-05 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT00847080
Treatment With Sitagliptin for Reactive Hypoglycemia Secondary to Dysinsulinism
Not yet reported Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran 20 participants Est. completion 2011-03 1 site Stand-aloneOther conditions: Reactive HypoglycemiaView official trial listing → -
Completed NCT NCT00851903
Evaluation of Insulin Glargine in Combination With Sitagliptin in Type 2 Diabetes Patients: EASIE Extension Trial
Not yet reported Sanofi 112 participants Est. completion 2011-09 16 sites Stand-aloneType 2 diabetesView official trial listing → -
Terminated NCT NCT00853944
Effect of Sitagliptin on Graft Function Following Islet Transplantation
Not yet reported University of British Columbia 12 participants Est. completion 2013-11-01 1 siteOther conditions: Islet TransplantationView official trial listing → -
Completed NCT NCT00854035
MK-0431/ONO-5435 Phase III Clinical Trial - Insulin Add-on Study for Patients With Type 2 Diabetes Mellitus
Not yet reported Ono Pharmaceutical Co., Ltd. 266 participants 7 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT00855166
Evaluation of the Effect of Dapagliflozin in Combination With Metformin on Body Weight in Subjects With Type 2 Diabetes
Not yet reported AstraZeneca 182 participants Est. completion 2011-12 21 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00860288
Efficacy and Long-Term Safety of Vildagliptin as Add-on Therapy to Metformin in Patients With Type 2 Diabetes
Not yet reported, Not yet reported Novartis Pharmaceuticals 1988 participants Est. completion 2011-03 187 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT00862719
Sitagliptin Umbilical Cord Blood Transplant Study
Not yet reported Indiana University 29 participants Est. completion 2015-02 1 site Stand-aloneOther conditions: Leukemia, Myeloid, Acute, Acute Lymphoblastic Leukemia, Myelodysplasia, Leukemia, Myelogenous, Chronic, Lymphoma, Non-HodgkinView official trial listing → -
Completed NCT NCT00870194
A Comparison of Adding Exenatide With Switching to Exenatide in Patients With Type 2 Diabetes Experiencing Inadequate Glycemic Control With Sitagliptin Plus Metformin
Not yet reported AstraZeneca 255 participants Est. completion 2010-04 36 sites Added to GLP-1Type 2 diabetesView official trial listing → -
Completed NCT NCT00871507
A Study to Evaluate the Safety, Tolerability, Pharmacokinetics (Explores What the Body Does to the Drug), and Pharmacodynamics (Explores What a Drug Does to the Body) of JNJ-38431055 in Volunteers With Type 2 Diabetes Mellitus
Not yet reported Johnson & Johnson Pharmaceutical Research & Development, L.L.C. 25 participants Est. completion 2009-07 2 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT00875394
Study to Assess the Efficacy and Safety of Sitagliptin Added to the Regimen of Patients With Type 2 Diabetes Mellitus With Inadequate Glycemic Control on Metformin (0431-189)
Not yet reported Merck Sharp & Dohme LLC 68 participants Est. completion 2008-06-27 Stand-aloneOther conditions: Diabetes Mellitus, Non-Insulin-DependentView official trial listing → -
Completed NCT NCT00881530
Empagliflozin (BI 10773) in Type Two Diabetes (T2D) Patients, Open Label Extension
Not yet reported Boehringer Ingelheim 660 participants 137 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT00881543
"Effect of Dipeptidyl Peptidase IV After Diets in näive Type 2 Diabetic Patients"
Not yet reported University of Sao Paulo General Hospital 45 participants Est. completion 2011-10 1 siteOther conditions: Diabetes Type 2View official trial listing → -
Completed NCT NCT00885352
Sitagliptin (MK-0431) vs. Placebo in Patients With Inadequate Glycemic Control on Metformin With Pioglitazone (MK-0431-128)
Not yet reported Merck Sharp & Dohme LLC 313 participants Est. completion 2010-11-10 Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00885638
Effects of Dipeptidyl Peptidase-4 (DPP-4) Inhibition on Hormonal Responses to Macronutrient Ingestion
Not yet reported Lund University 12 participants Est. completion 2012-09 1 siteType 2 diabetes Other conditions: HealthyView official trial listing → -
Completed NCT NCT00888238
A Method to Evaluate Glucose-Dependent Insulin Secretion in Healthy Males (MK-0431-179)
Not yet reported Merck Sharp & Dohme LLC 12 participants Est. completion 2009-07-21 Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00929201
Sitagliptin/Metformin Fed Bioequivalence Study (0431A-080)
Not yet reported Merck Sharp & Dohme LLC 61 participants Est. completion 2008-05Type 2 diabetesView official trial listing → -
Terminated NCT NCT00936663
Using Sitagliptin as a Treatment to Prevent New Onset Diabetes After Kidney Transplantation
Not yet reported University of Nebraska 3 participants Est. completion 2010-06-01 1 site Stand-aloneType 2 diabetes Other conditions: End Stage Renal DiseaseView official trial listing → -
Terminated NCT NCT00939939
Effect of Sitagliptin on Postprandial Lipoprotein Metabolism
Not yet reported Ludwig-Maximilians - University of Munich 3 participants Est. completion 2011-05 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00944450
Study of the Bioequivalence of Two Tablet Forms of MK0431 (0431-027)
Not yet reported Merck Sharp & Dohme LLC 12 participants Est. completion 2004-11Type 2 diabetesView official trial listing → -
Terminated NCT NCT00947011
Dipeptidyl Peptidase-4 Inhibition on Glucagon-like Peptide-1 (GLP-1)
Not yet reported Johns Hopkins University 12 participants Est. completion 2010-03 1 siteOther conditions: Glucose HomeostasisView official trial listing → -
Terminated NCT NCT00950534
Effectiveness and Safety of Two Approaches to the Management of Type 2 Diabetes Mellitus in Australian Primary Care
Not yet reported Sanofi 25 participants Est. completion 2010-08 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00957060
Superiority of Glimepiride Over Sitagliptin in Naive Type 2 Diabetes Patients
Not yet reported Sanofi 400 participants Est. completion 2010-10 2 sitesType 2 diabetesView official trial listing → -
Terminated NCT NCT00958269
Study to Evaluate Safety and Efficacy of Dutogliptin in Type 2 Diabetes Mellitus Subjects With Moderate and Severe Renal Impairment
Not yet reported Phenomix 360 participants Est. completion 2011-11 43 sitesType 2 diabetes Other conditions: Renal ImpairmentView official trial listing → -
Completed NCT NCT00960453
Clinical Trial to Investigate the Pharmacokinetics/Pharmacodynamics of Sitagliptin
Not yet reported Seoul National University Hospital 12 participants 1 siteOther conditions: Diabetes MellitusView official trial listing → -
Status unknown NCT NCT00961363
Effect of Sitagliptin in Impaired Glucose Tolerance
Not yet reported National Taiwan University Hospital 60 participants 1 site Stand-alonePrediabetesView official trial listing → -
Completed NCT NCT00961480
A Study to Demonstrate the Bioequivalence of Sitagliptin/Metformin Combination Tablets and Co-administration of Sitagliptin and Metformin as Individual Tablets (0431A-095)
Not yet reported Merck Sharp & Dohme LLC 24 participants Est. completion 2007-11 Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00961857
A Study to Demonstrate the Bioequivalence of Sitagliptin/Metformin Combination Tablets and Concomitant Administration of Sitagliptin and Metformin as Individual Tablets (0431A-048)
Not yet reported Merck Sharp & Dohme LLC 48 participants Est. completion 2006-01-01Type 2 diabetesView official trial listing → -
Completed NCT NCT00964184
Phenotypic and Genetic Correlates of Diabetes (Non-Type 1) in Young Non-Obese Asian Indians in North India and A Study to Evaluate the Efficacy of Sitagliptin (DPP-4 Inhibitor) in a Sub-group of the Study Population
Not yet reported Diabetes Foundation, India 133 participants Est. completion 2015-07 1 siteType 2 diabetesView official trial listing → -
Terminated NCT NCT00967798
Prevention of Cystic Fibrosis Diabetes
Not yet reported Emory University 33 participants Est. completion 2017-12-31 3 sites Stand-alonePrediabetes Other conditions: Cystic FibrosisView official trial listing → -
Completed NCT NCT00968006
Effect of Sitagliptin on Endothelial Progenitor Cells
Not yet reported University of Padova 40 participants Est. completion 2010-01 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00969566
Predictive Parameters for Efficacy of Sitagliptin and Metformin Combination
Not yet reported Seoul National University Bundang Hospital 150 participants Est. completion 2011-07 1 site Stand-aloneOther conditions: DiabetesView official trial listing → -
Completed NCT NCT00971659
Adjunctive Therapy of Exenatide or Sitagliptin to Insulin Glargine in Type 2 Diabetes
Not yet reported Profil Institut für Stoffwechselforschung GmbH 48 participants Est. completion 2008-11 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT00975052
A Study of the Effects of Sitagliptin (MK0431) and Metformin on Incretin Hormone Concentrations (0431-050)(COMPLETED)
Not yet reported Merck Sharp & Dohme LLC 16 participants Est. completion 2006-03 Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00976261
A 2-Part Trial in Subjects With Type 2 Diabetes and in Healthy Subjects to Evaluate GSK1614235, a New Glucose Lowering Drug to Treat Type 2 Diabetes
Not yet reported GlaxoSmithKline 72 participants Est. completion 2010-09-05 9 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT00976937
24-week Study Comparing Lixisenatide to Sitagliptin as add-on to Metformin in Obese Type 2 Diabetic Patients Younger Than 50 Years
Not yet reported Sanofi 319 participants Est. completion 2011-03 92 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT00978796
Assessing Glucose Effects of Sitagliptin (Januvia) in Adult Patients With Type 1 Diabetes
Not yet reported University of Colorado, Denver 20 participants Est. completion 2010-03 1 siteOther conditions: Type 1 DiabetesView official trial listing → -
Completed NCT NCT00984867
Dapagliflozin DPPIV Inhibitor add-on Study
Not yet reported AstraZeneca 833 participants Est. completion 2011-09 88 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT00993187
Efficacy and Safety of Sitagliptin/Metformin Fixed-Dose Combination (FDC) Compared to Glimepiride in Participants With Type 2 Diabetes Mellitus (MK-0431A-202)
Not yet reported Merck Sharp & Dohme LLC 292 participants Est. completion 2013-10-29Type 2 diabetesView official trial listing → -
Terminated NCT NCT00998686
Safety and Efficacy Study of Dutogliptin in Subjects With Type 2 Diabetes Mellitus on a Background Medication of Metformin
Not yet reported Phenomix 650 participants Est. completion 2011-11 44 sitesType 2 diabetesView official trial listing → -
Terminated NCT NCT01006018
DPP-4 Inhibition and TZD for DM Prevention
Not yet reported Emory University 3 participants Est. completion 2011-12 2 sites Stand-aloneOther conditions: Prediabetic StateView official trial listing → -
Completed NCT NCT01028391
30-Week Extension to an Initial Combination Study (24 Weeks in Duration) of Sitagliptin With Pioglitazone (0431-064)
Not yet reported Merck Sharp & Dohme LLC 317 participants Est. completion 2009-01-01 Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01035879
Study to Evaluate the Efficacy, Safety, Tolerability, and Pharmacokinetics of MBX-2982 Administered Daily for 4 Weeks as Monotherapy in Patients With Type 2 Diabetes
Not yet reported Gilead Sciences 100 participants Est. completion 2010-08 14 sites Stand-aloneOther conditions: DiabetesView official trial listing → -
Withdrawn NCT NCT01038648
Sitagliptin in Prevention of Type 2 Diabetes Mellitus
Not yet reported India Diabetes Research Foundation & Dr. A. Ramachandran's Diabetes Hospitals Est. completion 2014-12 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT01046110
Comparison of NN1250 With Sitagliptin in Subjects With Type 2 Diabetes Never Treated With Insulin
Not yet reported Novo Nordisk A/S 458 participants Est. completion 2010-11 93 sites Stand-aloneType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT01054118
A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Single Doses of JNJ-38431055, Sitagliptin, and Co-administration of JNJ-38431055 and Sitagliptin
Not yet reported Johnson & Johnson Pharmaceutical Research & Development, L.L.C. 18 participants Est. completion 2010-02 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01062048
Januvia Re-examination Study (MK-0431-181)
Merck Sharp & Dohme LLC 3483 participants Est. completion 2013-07Type 2 diabetesView official trial listing → -
Completed NCT NCT01065766
Sitagliptin/Metformin (JANUMET) Re-examination Study (0431A-182)
Merck Sharp & Dohme LLC 4065 participants Est. completion 2013-05Type 2 diabetesView official trial listing → -
Completed NCT NCT01073826
Role of Interleukin-6 in Exercise
Not yet reported University of Zurich 56 participants Est. completion 2016-06 1 siteType 2 diabetes Other conditions: ObesityView official trial listing → -
Completed NCT NCT01076075
A Study to Evaluate the Safety and Efficacy of Sitagliptin 100 mg in Participants With Type 2 Diabetes Mellitus Who Have Inadequate Glycemic Control (MK-0431-229)
Not yet reported Merck Sharp & Dohme LLC 427 participants Est. completion 2012-01-19 Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01076088
Safety and Efficacy of Co-Administration of Sitagliptin and Metformin in China (MK-0431-121)
Not yet reported Merck Sharp & Dohme LLC 744 participants Est. completion 2012-12-24 Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01077323
A Retrospective Cohort Study of Acute Pancreatitis in Relation to Use of Exenatide and Other Antidiabetic Agents
AstraZeneca 363766 participants Est. completion 2008-03 1 siteType 2 diabetes Other conditions: Healthy Subjects (Treated With no Diabetes Therapies)View official trial listing → -
Completed NCT NCT01081834
The CANTATA-M (CANagliflozin Treatment and Trial Analysis - Monotherapy) Trial
Not yet reported Janssen Research & Development, LLC 678 participants Est. completion 2012-03 78 sites Stand-aloneType 2 diabetesView official trial listing → -
Terminated NCT NCT01089790
Safety and Efficacy of Dutogliptin in Patients With Type 2 Diabetes Mellitus Receiving Background Treatment With Glimepiride Alone or in Combination With Metformin or With Pioglitazone Alone
Not yet reported Forest Laboratories 141 participants 149 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT01092663
The Effects of Co-admin of Colesevelam and Sitagliptin on Glucose Metabolism in Subjects With Type 2 Diabetes Mellitus
Not yet reported KineMed 61 participants Est. completion 2011-07 3 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT01093651
Dipeptidyl Peptidase-4 Inhibition and Immune Function in HIV
Not yet reported, Not yet reported Washington University School of Medicine 20 participants Est. completion 2012-06 1 siteOther conditions: Diabetes, Insulin ResistanceView official trial listing → -
Completed NCT NCT01093794
Bioequivalence Study of Sitagliptin/Metformin Combination Tablet (MK0431A-122)
Not yet reported Merck Sharp & Dohme LLC 28 participants Est. completion 2010-06Type 2 diabetesView official trial listing → -
Completed NCT NCT01095991
Investigate the Effect of AZD1656 on the Pharmacokinetics of Sitagliptin in Patients With Type 2 Diabetes Mellitus
Not yet reported AstraZeneca 12 participants Est. completion 2010-05 1 site Stand-aloneType 2 diabetesView official trial listing → -
Status unknown NCT NCT01096277
Vascular Effects of Sitagliptin in Diabetes Mellitus
Not yet reported Hannover Medical School 70 participants Est. completion 2012-12 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT01098539
A Study of the Efficacy and Safety of Albiglutide in Subjects With Type 2 Diabetes With Renal Impairment.
Not yet reported GlaxoSmithKline 507 participants Est. completion 2012-11 218 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT01099618
Ketosis-Prone Diabetes Mellitus (KPDM): Metformin Versus Sitagliptin Treatment
Not yet reported Dawn Smiley MD 48 participants Est. completion 2014-08 1 siteOther conditions: Ketosis Prone Diabetes, Diabetes Ketoacidosis, HyperglycemiaView official trial listing → -
Completed NCT NCT01100125
Sitagliptin Versus Insulin Dose Increase in Type 2 Diabetes on Insulin Treatment
Not yet reported Seoul National University Bundang Hospital 140 participants Est. completion 2012-11 2 sites Stand-aloneOther conditions: DiabetesView official trial listing → -
Completed NCT NCT01104532
A Study to Characterize the Effect on the Pharmacokinetics of ASP1941 and Sitagliptin When Given Together to Healthy Subjects
Not yet reported Astellas Pharma Inc 64 participants Est. completion 2010-03 1 site Stand-aloneOther conditions: Healthy, Pharmacokinetics of ASP1941View official trial listing → -
Completed NCT NCT01106677
The CANTATA-D Trial (CANagliflozin Treatment and Trial Analysis - DPP-4 Inhibitor Comparator Trial)
Not yet reported Janssen Research & Development, LLC 1284 participants Est. completion 2012-05 125 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT01106690
The CANTATA-MP Trial (CANagliflozin Treatment and Trial Analysis - Metformin and Pioglitazone)
Not yet reported Janssen Research & Development, LLC 344 participants Est. completion 2012-07 83 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT01112670
The Role of P-glycoprotein in Sitagliptin Clinical Pharmacology
Not yet reported University of Colorado, Denver 33 participants Est. completion 2011-07 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT01119846
A Study in Type 2 Diabetics of Single and Multiple Doses of Orally Administered GSK1292263 to Investigate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics
Not yet reported GlaxoSmithKline 100 participants Est. completion 2010-03-19 7 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01128621
A Study in Type 2 Diabetic Subjects on Stable Metformin Therapy to Investigate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Co-administering Single and Multiple Oral Doses of GSK1292263
Not yet reported GlaxoSmithKline 66 participants Est. completion 2010-04-12 2 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT01131182
Study of Sitagliptin Treatment in Patients With Type 2 Diabetes During Ramadan (0431-263)
Not yet reported Merck Sharp & Dohme LLC 1147 participants Est. completion 2010-11-04 Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01137812
The CANTATA-D2 Trial (CANagliflozin Treatment And Trial Analysis - DPP-4 Inhibitor Second Comparator Trial)
Not yet reported Janssen Research & Development, LLC 756 participants Est. completion 2012-03 184 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT01140438
Treatment of Latent Autoimmune Diabetes of the Adult
Not yet reported Norwegian University of Science and Technology 64 participants Est. completion 2018-11 1 siteOther conditions: DiabetesView official trial listing → -
Completed NCT NCT01155284
Combination Therapy With Sitagliptin and Lansoprazole to Restore Pancreatic Beta Cell Function in Recent-Onset Type 1 Diabetes
Not yet reported Sanford Health 70 participants Est. completion 2015-03 3 sites Stand-aloneOther conditions: Type 1 DiabetesView official trial listing → -
Completed NCT NCT01159847
Protective Effects of Sitagliptin on β Cell Function in Patients With Adult-onset Latent Autoimmune Diabetes (LADA)
Not yet reported, Not yet reported European Foundation for the Study of Diabetes 30 participants Est. completion 2012-12 1 siteOther conditions: Type 1 DiabetesView official trial listing → -
Completed NCT NCT01177384
Clinical Trial to Evaluate the Safety and Efficacy of the Addition of Sitagliptin in Participants With Type 2 Diabetes Mellitus Receiving Acarbose Monotherapy (MK-0431-130)
Not yet reported Merck Sharp & Dohme LLC 380 participants Est. completion 2013-03-25 Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01177813
Efficacy and Safety of Empagliflozin (BI 10773) Versus Placebo and Sitagliptin Over 24 Weeks in Patients With Type 2 Diabetes
Not yet reported Boehringer Ingelheim 986 participants 124 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT01183104
START-J: SiTAgliptin in eldeRly Trial in Japan
Not yet reported Japan Association for Diabetes Education and Care 305 participants Est. completion 2015-01 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01186562
Sitagliptin Therapy to Improve Outcomes After Islet Autotransplant
Not yet reported University of Minnesota 83 participants Est. completion 2016-06 1 siteOther conditions: Pancreatitis, DiabetesView official trial listing → -
Completed NCT NCT01189890
Safety and Efficacy of Sitagliptin Compared With Glimepiride in Elderly Participants With Type 2 Diabetes Mellitus (MK-0431-251)
Not yet reported Merck Sharp & Dohme LLC 480 participants Est. completion 2012-10-31 Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01193296
Glycemic Holter Study (Continuous Glucose Monitoring) -
Not yet reported Novartis 36 participants Est. completion 2011-06 7 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT01195090
Adding Sitagliptin or Pioglitazone to Type 2 Diabetes Mellitus Insufficiently Controlled With Metformin and Sulfonylurea
Not yet reported Sung-Chen Liu 120 participants Est. completion 2012-04 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT01235819
Comparison Between GLP 1 Analogues and DPP 4 Inhibitors in Type 1 Diabetes Mellitus
Not yet reported Command Hospital, India 20 participants Est. completion 2011-09 1 siteOther conditions: Type 1 DiabetesView official trial listing → -
Completed NCT NCT01242228
A Study to Assess the Safety and Efficacy of ASP1941 in Combination With Dipeptidyl Peptidase-4 (DPP-4) Inhibitor in Type 2 Diabetic Patients
Not yet reported Astellas Pharma Inc 106 participants Est. completion 2012-06-06 6 sitesType 2 diabetesView official trial listing → -
Terminated NCT NCT01257464
Sitagliptin in Cystic Fibrosis-Related Diabetes
Not yet reported University of British Columbia 3 participants Est. completion 2012-06 1 siteOther conditions: Cystic FibrosisView official trial listing → -
Terminated NCT NCT01260246
Sitagliptin for the Treatment of Non-alcoholic Steatohepatitis in Patients With Type 2 Diabetes
Not yet reported London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's 12 participants Est. completion 2015-04 1 site Stand-aloneType 2 diabetesMASHView official trial listing → -
Completed NCT NCT01269996
JanUmet Before Insulin Lantus In Eastern Population Evaluation Program (JUBILEE) In Type 2 Diabetic Patients
Not yet reported Chinese University of Hong Kong 71 participants Est. completion 2015-02 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT01272583
Dipeptidyl Peptidase-4 Inhibitors and Alpha-cell Recovery
Not yet reported Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) 16 participants Est. completion 2012-10 1 siteOther conditions: Type 1 Diabetes, HypoglycemiaView official trial listing → -
Completed NCT NCT01278485
Evaluation of Low Blood Sugar Events in Participants With Diabetes (MK-0431-402)
Merck Sharp & Dohme LLC 726 participants Est. completion 2012-06Type 2 diabetesView official trial listing → -
Completed NCT NCT01285076
Evaluation of Low Blood Sugar Events in Participants With Diabetes (MK-0431-401)
Merck Sharp & Dohme LLC 834 participants Est. completion 2012-12-27 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT01289990
Safety and Efficacy of Empagliflozin (BI 10773) and Sitagliptin Versus Placebo Over 76 Weeks in Patients With Type 2 Diabetes
Not yet reported Boehringer Ingelheim 2705 participants Est. completion 2013-05 243 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01296412
Comparison of Two Treatment Regimens (Sitagliptin Versus Liraglutide) on Participants Who Failed to Achieve Good Glucose Control on Metformin Alone (MK-0431-403)
Not yet reported Merck Sharp & Dohme LLC 653 participants Est. completion 2012-02-29 Stand-aloneType 2 diabetesView official trial listing → -
Status unknown NCT NCT01316835
Effectiveness of Sitagliptin in Glycemic Control in Real World
Chang Gung Memorial Hospital 1120 participants Est. completion 2011-12 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT01332370
Prescription Patterns, Resource Utilization & Costs - Add-on Therapy With Anti Dipeptidyl Peptidase-IVs vs Rosiglitazone
GlaxoSmithKline 5391 participants Est. completion 2010-12Type 2 diabetesView official trial listing → -
Completed NCT NCT01334229
Sitagliptin and Kinetics of Triglyceride-rich Lipoproteins Apolipoprotein B48 and B100 in Patients With Type 2 Diabetes
Not yet reported Laval University 22 participants Est. completion 2013-12 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01336322
Metformin and Sitagliptin in Women With Previous Gestational Diabetes
Not yet reported University of Pisa 40 participants Est. completion 2018-12 1 sitePrediabetesView official trial listing → -
Completed NCT NCT01336738
Study Of Safety And Efficacy Of PF-04991532 In Subjects With Type 2 Diabetes Mellitus
Not yet reported Pfizer 266 participants Est. completion 2012-03 44 sitesOther conditions: Diabetes, Type 2View official trial listing → -
Status unknown NCT NCT01337440
Efficacy and Safety of Ursodeoxycholic Acid (UDCA) Added to the DPP-4 Inhibitor in People With Type 2 Diabetes and Chronic Liver Diseases
Not yet reported Kanazawa University 20 participants Est. completion 2013-03 1 siteType 2 diabetes Other conditions: Chronic Liver DiseaseView official trial listing → -
Completed NCT NCT01338870
Study of Safety and Efficacy of PF-04991532 in Subjects With Type 2 Diabetes
Not yet reported Pfizer 301 participants Est. completion 2012-03 42 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT01340768
Study to Compare Sitagliptin Versus Sulfonylurea Treatment During Ramadan Fasting in Patients With Type 2 Diabetes (MK-0431-262)
Not yet reported Merck Sharp & Dohme LLC 870 participants Est. completion 2011-09-21 Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01341717
Effects of Sitagliptin on Type 2 Diabetes Mellitus Patients on Treatment With Metformin and Insulin
Not yet reported Jothydev's Diabetes and Research Centre 440 participants Est. completion 2014-05 1 site Stand-aloneType 2 diabetesView official trial listing → -
Status unknown NCT NCT01341795
Genetic Variation in the Transporters and Hypoglycemic Agents
Ajou University School of Medicine 100 participants 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT01342939
Pathophysiological Implications of the Incretin Hormones in Maturity Onset of Diabetes of the Young (MODY)
University Hospital, Gentofte, Copenhagen 31 participants Est. completion 2011-12 1 siteOther conditions: Maturity-onset Diabetes of the YoungView official trial listing → -
Completed NCT NCT01349387
Effect of Treatment With Metformin in Type 2 Diabetes Patients on Alternative Genes Splicing
Not yet reported Centre d'Etudes et de Recherche pour l'Intensification du Traitement du Diabète 25 participants Est. completion 2012-01 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT01354990
A Post Marketing Safety Study of Sitagliptin (JANUVIA®) (MK-0431-234)
Merck Sharp & Dohme LLC 2974 participants Est. completion 2010-05Type 2 diabetesView official trial listing → -
Completed NCT NCT01357135
An Observational Study of Type II Diabetics Treated With Dual Therapy With or Without Sitagliptin (Januvia®/Xelevia®, MK-0431-201)
Merck Sharp & Dohme LLC 3453 participants Est. completion 2013-08-31Type 2 diabetesView official trial listing → -
Terminated NCT NCT01357148
A Post Marketing Safety Study of Sitagliptin Phosphate/Metformin Hydrochloride (JANUMET®) (MK-0431A-235)
Merck Sharp & Dohme LLC 143 participants Est. completion 2010-05Type 2 diabetesView official trial listing → -
Terminated NCT NCT01374568
Changes in Bone Turnover With Increased Incretin Hormone Exposure
Not yet reported University of Alabama at Birmingham 6 participants Est. completion 2015-09 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT01376323
A Study of GSK256073 in Subjects With Type 2 Diabetes Mellitus Who Are Being Treated With Metformin
Not yet reported GlaxoSmithKline 92 participants Est. completion 2012-09-17 15 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT01378117
Dipeptidyl Peptidase-4 Inhibitor (Sitagliptin) Therapy in the Inpatients With Type 2 Diabetes
Not yet reported Emory University 90 participants Est. completion 2012-06 2 sites Stand-aloneType 2 diabetes Other conditions: Hospitalization, HyperglycemiaView official trial listing → -
Completed NCT NCT01398592
Vildagliptin Versus Sitagliptin - Differences in Fasting Plasma Glucose Lowering Efficacy
Not yet reported Novartis Pharmaceuticals 187 participants Est. completion 2012-06 15 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT01405911
Dose Response Finding Study of MK-0431/ONO-5435 in Japanese Subjects With Impaired Glucose Tolerance (MK-0431-105)
Not yet reported Merck Sharp & Dohme LLC 242 participants Est. completion 2012-04-09 Stand-aloneOther conditions: Glucose IntoleranceView official trial listing → -
Completed NCT NCT01408888
A Study of LY2189265 and Sitagliptin in Participants With Type 2 Diabetes
Not yet reported Eli Lilly and Company 29 participants Est. completion 2012-04 3 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01409213
A Study of the Current Medical Practice and Outcomes in the Treatment of Type 2 Diabetes Mellitus in an Office Setting (MK-0431-199)
Merck Sharp & Dohme LLC 1523 participants Est. completion 2011-01Type 2 diabetesView official trial listing → -
Completed NCT NCT01413542
Pharmacogenetics of Ace Inhibitor-Associated Angioedema
Not yet reported Vanderbilt University 44 participants Est. completion 2014-07 1 siteOther conditions: Hypertension, Diabetes Type 2View official trial listing → -
Completed NCT NCT01414920
Efficacy and Safety of TAK-875 in Combination With Sitagliptin in Participants With Type 2 Diabetes Mellitus
Not yet reported Takeda 368 participants Est. completion 2012-08 80 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT01422590
Pharmacodynamics of Mitiglinide/Sitagliptin Compared to Mitiglinide and Sitagliptin
Not yet reported Samsung Medical Center 26 participants Est. completion 2011-04 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01441232
A Study to Evaluate the Pharmacodynamic Effects of Single-Dose Co-Administration of LX4211 With Januvia® in Type 2 Diabetics
Not yet reported Lexicon Pharmaceuticals 18 participants 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01449747
Pharmacokinetics Study of Dipeptidyl Peptidase 4 Inhibitor to Control Type 2 Diabetes Mellitus
Not yet reported The Catholic University of Korea 24 participants Est. completion 2015-07 2 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT01455870
A Study to Evaluate ITCA 650 Compared to Sitagliptin as add-on Therapy for the Treatment of Type 2 Diabetes
Not yet reported Intarcia Therapeutics 535 participants Est. completion 2015-07 54 sitesType 2 diabetesView official trial listing → -
Withdrawn NCT NCT01455909
A Study to Evaluate ITCA 650 Compared to Sitagliptin for the Treatment of Type 2 Diabetes
Not yet reported Intarcia Therapeutics Est. completion 2014-07 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT01462266
Study of Sitagliptin for the Treatment of Type 2 Diabetes Mellitus With Inadequate Glycemic Control on Insulin (MK-0431-260)
Not yet reported Merck Sharp & Dohme LLC 660 participants Est. completion 2013-06-07 Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01471808
Effects of Different Early Intensive Therapies on Long-term β-cell Function
Not yet reported Sun Yat-sen University 264 participants Est. completion 2018-12Type 2 diabetesView official trial listing → -
Completed NCT NCT01475461
Phase 2 Study To Evaluate Safety And Efficacy Of Investigational Drug - PF04937319 In Patients With Type 2 Diabetes
Not yet reported Pfizer 345 participants Est. completion 2013-01 63 sitesType 2 diabetesView official trial listing → -
Terminated NCT NCT01477853
A Study of the Co-administration of Sitagliptin and Atorvastatin in Inadequately Controlled Type 2 Diabetes Mellitus (MK-0431E-211)
Not yet reported Merck Sharp & Dohme LLC 166 participants Est. completion 2012-12-04 Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01485614
Study to Assess Safety & Efficacy of Sitagliptin as Initial Oral Therapy for Treatment of Type 2 Diabetes Mellitus in Pediatric Participants. (MK-0431-083)
Not yet reported Merck Sharp & Dohme LLC 200 participants Est. completion 2019-10-09 Stand-aloneType 2 diabetes Other conditions: Diabetes MellitusView official trial listing → -
Completed NCT NCT01488279
Effect of Sitagliptin on Short-Term Metabolic Dysregulation of Oral Glucocorticoid Therapy
Not yet reported University of Vermont 10 participants Est. completion 2015-12 1 sitePrediabetesView official trial listing → -
Completed NCT NCT01490918
Study to Evaluate the Efficacy of Acarbose,Metformin,Sitagliptin Combination Treatment in DM Patients
Not yet reported The Catholic University of Korea 165 participants Est. completion 2014-09 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT01512797
Treatment of Diabetes After Gastric Bypass With Sitagliptin
Not yet reported Blandine Laferrere 37 participants Est. completion 2016-08 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT01517321
MK-0431/ONO-5435 Phase III Clinical Trial-Rapid-acting Insulin Secretagogue Add-on Study in Patients With Type 2 Diabetes
Not yet reported Ono Pharmaceutical Co., Ltd. 6 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT01519674
Treatment Intensification With Biphasic Insulin Aspart 30 in Subjects With Type 2 Diabetes Inadequately Controlled on Sitagliptin and Metformin
Not yet reported Novo Nordisk A/S 582 participants Est. completion 2013-10 69 sitesType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT01529541
Efficacy and Safety of CWP-0403 Compared to Sitagliptin in Patients With Type 2 Diabetes Mellitus Insufficiently Controlled With Metformin Alone
Not yet reported JW Pharmaceutical 200 participants Est. completion 2013-10 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT01530178
Sitagliptin Dose Determination Study
Not yet reported Albert Einstein College of Medicine 8 participants Est. completion 2015-03 1 siteOther conditions: Diabetes Mellitus, Type 1View official trial listing → -
Status unknown NCT NCT01545024
Effect of DPP-IV Inhibitor on Glycemic Control and Autonomic Neuropathy in Adult Patients With Diabetes Mellitus
Nagaoka Red Cross Hospital 60 participants Est. completion 2013-01 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT01545388
Metformin Add-on Regimen Comparison Study in Japanese Participants With Type 2 Diabetes Mellitus (MK-0431A-136)
Not yet reported Merck Sharp & Dohme LLC 337 participants Est. completion 2013-03-12 Stand-aloneType 2 diabetesView official trial listing → -
Terminated NCT NCT01549964
Comparison of Fasiglifam (TAK-875) to Placebo and Sitagliptin in Combination With Metformin in Participants With Type 2 Diabetes
Not yet reported Takeda 916 participants Est. completion 2014-03 160 sites Stand-aloneOther conditions: Glycemic ControlView official trial listing → -
Completed NCT NCT01557504
A Study to Assess the Pharmacokinetics and the Ability for Pediatric Participants With Type 2 Diabetes to Swallow MK-0431A XR Tablets (MK-0431A-296)
Not yet reported Merck Sharp & Dohme LLC 25 participants Est. completion 2014-04-29Type 2 diabetesView official trial listing → -
Terminated NCT NCT01567540
A Pilot Study Evaluating Safety of Sitagliptin Combined With Peg-IFN Alfa-2a + Ribavirin in Chronic Hepatitis C Patients
Not yet reported Institut National de la Santé Et de la Recherche Médicale, France 3 participants Est. completion 2014-01 4 sites Stand-aloneOther conditions: Hepatitis CView official trial listing → -
Completed NCT NCT01582308
A Study Comparing the Pharmacokinetic and Pharmacodynamic Profiles for Sitagliptin, Saxagliptin and Vildagliptin in Participants With Type 2 Diabetes Mellitus (T2DM) (MK-0431-142)
Not yet reported Merck Sharp & Dohme LLC 22 participants Est. completion 2012-12-14 Stand-aloneType 2 diabetesView official trial listing → -
Status unknown NCT NCT01588587
DPP-IV Inhibitors Underlying Mechanism of Cancer in Diabetic Patients
Nagaoka Red Cross Hospital 500 participants Est. completion 2017-12 2 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT01590771
A Study in China Evaluating the Safety and Efficacy of Adding Sitagliptin to Stable Therapy With Sulfonylurea With or Without Metformin in Participants With Type 2 Diabetes Mellitus (T2DM) (MK-0431-253)
Not yet reported Merck Sharp & Dohme LLC 498 participants Est. completion 2014-06-24Type 2 diabetesView official trial listing → -
Completed NCT NCT01590797
A Study in China Evaluating the Safety and Efficacy of Adding Sitagliptin to Stable Therapy With Insulin With or Without Metformin in Participants With Type 2 Diabetes Mellitus (T2DM) (MK-0431-254)
Not yet reported Merck Sharp & Dohme LLC 467 participants Est. completion 2014-06-25 Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01600703
Sitagliptin Regulation of Intestinal and Hepatic Lipoprotein Particle and Hepatic Glucose Production in Humans
Not yet reported, Not yet reported University Health Network, Toronto 21 participants Est. completion 2013-08 1 site Stand-aloneOther conditions: HyperlipidemiaView official trial listing → -
Completed NCT NCT01602003
Phase III Trial to Evaluate the Efficacy and Safety of LC15-0444 Compared With Sitagliptin Added to Ongoing Metformin Therapy in Patients With Type 2 Diabetes
Not yet reported LG Life Sciences 425 participants Est. completion 2012-05 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01610154
Contribution of Pancreatic αcells Function to Blood Glucose Regulation in Chinese Type 2 Diabetics- the Effect of Sitagliptin on Glucagon Secretion, Insulin Secretion and Insulin Resistance in Chinese Type 2 Diabetics
Not yet reported Guangwei Li 85 participants Est. completion 2015-06 1 siteOther conditions: Insulin Secretion, Insulin ResistanceView official trial listing → -
Completed NCT NCT01619332
Clinical Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of LEZ763
Not yet reported, Not yet reported Novartis Pharmaceuticals 220 participants Est. completion 2013-09 6 sitesOther conditions: Type II DiabetesView official trial listing → -
Completed NCT NCT01624116
Comparison of Hypoglycaemic Regimens During Ramadan Fasting in Type 2 Diabetes
Not yet reported Services Hospital, Lahore 161 participants Est. completion 2011-09 1 siteOther conditions: Diabetes, Type 2View official trial listing → -
Status unknown NCT NCT01642108
Treatment With Sitagliptin in Non-obese Japanese Patients With Type 2 Diabetes Mellitus
Not yet reported Niigata Medical Center 40 participants Est. completion 2013-06 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT01652729
Comparison Study of the Glycemic Effects, Safety, and Tolerability of Exenatide Once Weekly Suspension to Sitagliptin and Placebo in Subjects With Type 2 Diabetes Mellitus
Not yet reported AstraZeneca 365 participants Est. completion 2014-04 60 sitesOther conditions: Diabetes Type 2View official trial listing → -
Status unknown NCT NCT01660386
Study of Comparing the Different Effect of DPP-4 Inhibitors and Sulfonylurea by Using "Biphase-Hyperglycemic Clamp"
Not yet reported Shanghai Jiao Tong University School of Medicine 12 participants Est. completion 2013-03 1 siteType 2 diabetesView official trial listing → -
Terminated NCT NCT01678820
A Study of the Efficacy and Safety of MK-0431D (a Fixed-dose Combination of Sitagliptin and Simvastatin) for the Treatment of Participants With Type 2 Diabetes Mellitus (T2DM) With Inadequate Glycemic Control on Metformin Monotherapy (MK-0431D-266)
Not yet reported Merck Sharp & Dohme LLC 299 participants Est. completion 2013-11-01 Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01686932
Vildagliptin vs Sitagliptin add-on to Insulin - Impact on Glycemic Profile and Correlation of Hypoglycemic Episodes and Heart Function
Not yet reported Novartis Pharmaceuticals 51 participants Est. completion 2014-09 11 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01701973
Effect of DPP4 Inhibition on Growth Hormone Secretion
Not yet reported Vanderbilt University 44 participants Est. completion 2017-05 1 siteOther conditions: ObesityView official trial listing → -
Completed NCT NCT01702298
A Study to Assess the Safety and Tolerability of Sitagliptin/Simvastatin Fixed-dose Combination (FDC) in Participants With Type 2 Diabetes Mellitus With Inadequate Glycemic Control on Metformin Monotherapy (MK-0431D-312)
Not yet reported Merck Sharp & Dohme LLC 42 participants Est. completion 2013-05-29 Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01703221
Omarigliptin (MK-3102) Clinical Trial - Placebo- and Sitagliptin-Controlled Monotherapy Study in Japanese Patients With Type 2 Diabetes Mellitus (MK-3102-020)
Not yet reported Merck Sharp & Dohme LLC 414 participants Est. completion 2014-04-25 Stand-aloneType 2 diabetesView official trial listing → -
Status unknown NCT NCT01703637
Efficacy and Safety Comparative Study of Sitagliptin,Vildagliptin and Saxagliptin
Not yet reported Lin Liao 300 participants 8 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01709305
A Study of the Safety and Efficacy of Glimepiride, Gliclazide, Repaglinide or Acarbose When Added to Sitagliptin + Metformin Combination Therapy in Chinese Participants With Diabetes (MK-0431-313)
Not yet reported Merck Sharp & Dohme LLC 5570 participants Est. completion 2015-04-17 Stand-aloneType 2 diabetesView official trial listing → -
Status unknown NCT NCT01717911
ß-Cell Function and Glycemic Control in Newly Diagnosed Type 2 Diabetic Patients With Moderate Hyperglycemia
Not yet reported Taipei Veterans General Hospital, Taiwan 160 participants Est. completion 2018-12 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01718093
A Pilot Study to Assess the Glucose Lowering Effect of Metformin and Sitagliptin in Adolescents With Type 1 Diabetes
Not yet reported Baylor College of Medicine 21 participants Est. completion 2015-12 1 siteOther conditions: Type 1 DiabetesView official trial listing → -
Completed NCT NCT01720264
Multicenter Phase II of CD26 Using Sitagliptin for Engraftment After UBC Transplant
Not yet reported Sherif S. Farag 15 participants Est. completion 2017-12-15 2 sitesOther conditions: Acute Myeloid Leukemia, Acute Lymphoid Leukemia, Hematopoetic Myelodysplasia, Leukemia, Myelogenous, Chronic, Lymphoma, Non-HodgkinView official trial listing → -
Completed NCT NCT01721382
Treatment of Dysglycemia Using Sitagliptin in Adolescents With Cystic Fibrosis
Not yet reported Nemours Children's Clinic 6 participants Est. completion 2016-06 1 site Stand-aloneOther conditions: Cystic FibrosisView official trial listing → -
Completed NCT NCT01744236
SAFEGUARD: Pleiotropic Effects of Incretin Based Therapies
Not yet reported Amsterdam UMC, location VUmc 70 participants Est. completion 2015-08 1 site Added to GLP-1Type 2 diabetesView official trial listing → -
Status unknown NCT NCT01751321
Glucose Variability With DPP-4 Inhibition
Not yet reported Research Clinical Centre of the Russian Railways, JSC 50 participants Est. completion 2013-10Type 2 diabetesView official trial listing → -
Completed NCT NCT01760447
A Pooled Analysis of the Safety and Efficacy of MK-0431A and MK-0431A XR in Pediatric Participants With Type 2 Diabetes Mellitus With Inadequate Glycemic Control on Metformin Therapy (Alone or in Combination With Insulin) (MK-0431A-170/MK-0431A-289)
Not yet reported Merck Sharp & Dohme LLC 223 participants Est. completion 2019-09-17 Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01767389
Glucagon-like Peptide (GLP) Utilization and Safety
GlaxoSmithKline 1 participants Est. completion 2013-12Type 2 diabetesView official trial listing → -
Completed NCT NCT01785043
Differences in Endothelial Function Amongst Sitagliptin and Liraglutide Users
Not yet reported Anna Cruceta 13 participants Est. completion 2014-09 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT01794143
A Comparative Effectiveness Study of Major Glycemia-lowering Medications for Treatment of Type 2 Diabetes
Not yet reported GRADE Study Group 7850 participants Est. completion 2021-04-30 36 sitesType 2 diabetes Other conditions: Comparative Effectiveness of Glycemia-lowering MedicationsView official trial listing → -
Completed NCT NCT01820104
Effects of Lansoprazole on Sitagliptin Glucose-lowering Ability in Healthy Males: a Randomised Crossover Study
Not yet reported Xijing Hospital 16 participants Est. completion 2013-05 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Withdrawn NCT NCT01824264
Dose-finding Study of LIK066 Compared With Placebo or Sitagliptin to Evaluate Change in HbA1c in Patients With Diabetes
Not yet reported Novartis Pharmaceuticals Est. completion 2016-11Type 2 diabetesView official trial listing → -
Terminated NCT NCT01829464
TAK-875 (Fasiglifam) in Combination With Sitagliptin in Adults With Type 2 Diabetes
Not yet reported Takeda 90 participants Est. completion 2014-03 86 sitesOther conditions: DiabetesView official trial listing → -
Terminated NCT NCT01834274
Comparison of Fasiglifam (TAK-875) With Sitagliptin When Used in Combination With Metformin in Patients With Type 2 Diabetes
Not yet reported Takeda 96 participants Est. completion 2014-03 104 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01841697
Study to Evaluate the Safety and Efficacy of the Addition of Omarigliptin (MK-3102) Compared With the Addition of Sitagliptin in Participants With Type 2 Diabetes Mellitus With Inadequate Glycemic Control on Metformin (MK-3102-026)
Not yet reported Merck Sharp & Dohme LLC 642 participants Est. completion 2014-11-17 Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01845831
Sitagliptin Therapy in Hospitalized Patients With Type 2 Diabetes
Not yet reported Emory University 292 participants Est. completion 2016-04 5 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01847144
MASTERMIND - Understanding Individual Variation in Treatment Response in Type 2 Diabetes
Not yet reported Royal Devon and Exeter NHS Foundation Trust 143 participants Est. completion 2015-02 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT01855087
Safety and Efficacy of Sitagliptin Added to Insulin Therapy for Type 2 Diabetes
Kanagawa Physicians Association 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT01856907
Sitagliptin + Metformin Compared to Metformin Monotherapy and Placebo in Women With a Recent GDM
Not yet reported Woman's 36 participants Est. completion 2017-09-28 1 site Stand-aloneOther conditions: Disorder of Glucose RegulationView official trial listing → -
Completed NCT NCT01859793
Effects of Sitagliptin on Endothelial Function in Type 2 Diabetes on Background Metformin Therapy
Not yet reported Medical College of Wisconsin 38 participants Est. completion 2016-07 1 siteOther conditions: Diabetes, AtherosclerosisView official trial listing → -
Completed NCT NCT01863147
Sitagliptin Reduces Left Ventricular Mass in Normotensive Type 2 Diabetic Patients With Coronary Artery Disease
Not yet reported Wuhan General Hospital of Guangzhou Military Command 66 participants Est. completion 2015-07 2 sites Stand-aloneType 2 diabetesCardiovascular diseaseView official trial listing → -
Completed NCT NCT01879228
Effect of Chronic Incretin-based Therapy in Cystic Fibrosis
Not yet reported University of Pennsylvania 26 participants Est. completion 2020-03 1 siteOther conditions: Cystic Fibrosis, Pancreatic InsufficiencyView official trial listing → -
Completed NCT NCT01890629
Effects of Gemigliptin Versus Sitagliptin or Glimepiride With Metformin on Glucose Variability(MAGE, Glucose SD) Patients With Type 2 DM(STABLE Study)
Not yet reported LG Life Sciences 69 participants Est. completion 2014-08 1 site Stand-aloneType 2 diabetesView official trial listing → -
Status unknown NCT NCT01895569
Triple Therapy in Type 2 Diabetic Patients
Not yet reported University of Pavia 64 participants Est. completion 2016-06 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01901861
Effect of the DPP-4 Inhibitor Sitagliptin on Islet Function After Mixed Meal in Patients With Type 2 Diabetes
Not yet reported Lund University 12 participants Est. completion 2015-12 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT01907854
Efficacy and Safety of Switching From Sitagliptin to Liraglutide in Subjects With Type 2 Diabetes Not Achieving Adequate Glycaemic Control on Sitagliptin and Metformin
Not yet reported Novo Nordisk A/S 407 participants Est. completion 2015-06-15 106 sites Added to GLP-1Type 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT01928199
Efficacy Study of Sitagliptin to Prevent New-onset Diabetes After Kidney Transplant
Not yet reported Washington University School of Medicine 61 participants Est. completion 2020-10 1 siteOther conditions: Posttransplant Diabetes MellitusView official trial listing → -
Completed NCT NCT01930188
Efficacy and Safety of Semaglutide Once-weekly Versus Sitagliptin Once-daily as add-on to Metformin and/or TZD in Subjects With Type 2 Diabetes
Not yet reported Novo Nordisk A/S 1231 participants Est. completion 2015-10-12 141 sites Added to GLP-1Type 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT01933672
Study Of Two Dosing Regimens Of PF-04937319 Compared To An Approved Agent (Sitagliptin) In Patients With Type 2 Diabetes
Not yet reported Pfizer 33 participants Est. completion 2014-03 8 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT01936025
A Study to Investigate the Glucose Lowering Effects of Dextromethorphan Alone or in Combination With Sitagliptin in Subjects With Type 2 Diabetes Mellitus (T2DM) After an Oral Glucose Tolerance Test
Not yet reported Profil Institut für Stoffwechselforschung GmbH 34 participants Est. completion 2014-04 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01937598
Antidiabetic Effects of Adding a DPP-4 Inhibitor to Pre-Existing Treatment With an Incretin Mimetic in Patients With T2D
Not yet reported Michael A. Nauck 16 participants Est. completion 2015-06 1 site Added to GLP-1Type 2 diabetesView official trial listing → -
Terminated NCT NCT01944618
forREAL: FORXIGA PRESCRIPTION EVENT MONITORING PROGRAM (PEMP)
AstraZeneca 5000 participants Est. completion 2015-10 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT01951339
Impact of Sitagliptin on Cardiovascular Exercise Performance in Type 2 Diabetes
Not yet reported University of Colorado, Denver 36 participants Est. completion 2018-06 1 site Stand-aloneType 2 diabetesCardiovascular diseaseView official trial listing → -
Completed NCT NCT01963845
Sitagliptin Versus Placebo in the Treatment of Non-alcoholic Fatty Liver Disease
Not yet reported University of California, San Diego 50 participants Est. completion 2016-01 1 site Stand-aloneOther conditions: Non-alcoholic Fatty Liver DiseaseView official trial listing → -
Completed NCT NCT01969357
A Study of the Effectiveness and Safety of SP2086 to Treat Type 2 Diabetes
Not yet reported Jiangsu HengRui Medicine Co., Ltd. 200 participants Est. completion 2012-06 1 siteType 2 diabetesView official trial listing → -
Terminated NCT NCT01970462
Use of Sitagliptin for Stress Hyperglycemia or Mild Diabetes Following Cardiac Surgery
Not yet reported Kathleen Dungan 8 participants Est. completion 2016-08 1 site Stand-aloneType 2 diabetes Other conditions: HyperglycemiaView official trial listing → -
Status unknown NCT NCT01974544
Prevention and Treatment Of Diabetes Complications With Gastric Surgery or Intensive Medicines
Not yet reported Pontificia Universidad Catolica de Chile 150 participants Est. completion 2016-12 1 site Stand-aloneType 2 diabetesView official trial listing → -
Withdrawn NCT NCT01984606
Efficacy and Safety of Empagliflozin Versus Sitagliptin in Patients With Type 2 Diabetes
Not yet reported Boehringer Ingelheim Est. completion 2017-02Type 2 diabetesView official trial listing → -
Completed NCT NCT01991197
Dipeptidyl Peptidase-4 Inhibition in Psoriasis Patients With Diabetes (DIP): A Randomized Clinical Trial.
Not yet reported University College Dublin 20 participants Est. completion 2016-01 2 sites Stand-aloneType 2 diabetes Other conditions: PsoriasisView official trial listing → -
Completed NCT NCT01999218
Ertugliflozin vs. Glimepiride in Type 2 Diabetes Mellitus (T2DM) Participants on Metformin (MK-8835-002)
Not yet reported Merck Sharp & Dohme LLC 1326 participants Est. completion 2017-04-18 Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT02008682
The Efficacy and Safety of Liraglutide Compared to Sitagliptin, Both in Combination With Metformin in Chinese Subjects With Type 2 Diabetes
Not yet reported Novo Nordisk A/S 368 participants Est. completion 2014-11 25 sitesType 2 diabetes Other conditions: DiabetesView official trial listing → -
Terminated NCT NCT02015910
Januvia (Sitagliptin) in Healing Chronic Diabetic Foot Ulcers
Not yet reported Georgetown University 1 participants Est. completion 2015-01 1 site Stand-aloneOther conditions: Type II DiabetesView official trial listing → -
Completed NCT NCT02025907
A Study to Evaluate the Efficacy and Safety of the Addition of Canagliflozin in Participants With Type 2 Diabetes Mellitus With Inadequate Glycemic Control on Metformin and Sitagliptin
Not yet reported Janssen Research & Development, LLC 218 participants Est. completion 2015-09 57 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT02036515
Safety and Efficacy of Ertugliflozin in the Treatment of Participants With Type 2 Diabetes Mellitus Who Have Inadequate Glycemic Control on Metformin and Sitagliptin (MK-8835-006; VERTIS SITA2)
Not yet reported Merck Sharp & Dohme LLC 464 participants Est. completion 2016-06-06 Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT02041234
Roux-en-Y Gastric Bypass for BMI 27-32 Type 2 Diabetes Versus Best Medical Treatment
Not yet reported Khoo Teck Puat Hospital 40 participants Est. completion 2022-06 1 siteOther conditions: Type II Diabetes in Subjects BMI 27 to 32View official trial listing → -
Completed NCT NCT02043054
Effects of Liraglutide in Young Adults With Type 2 DIAbetes (LYDIA)
Not yet reported University of Leicester 90 participants Est. completion 2017-09-29 1 siteType 2 diabetesCardiovascular diseaseView official trial listing → -
Terminated NCT NCT02048904
Use of Sitagliptin to Decrease Microalbuminuria
Not yet reported University of Missouri-Columbia 142 participants Est. completion 2016-06 1 siteType 2 diabetes Other conditions: MicroalbuminuriaView official trial listing → -
Completed NCT NCT02060383
Study of Management of Pasireotide-induced Hyperglycemia in Adult Patients With Cushing's Disease or Acromegaly
Not yet reported Novartis Pharmaceuticals 249 participants Est. completion 2018-03-26 43 sites Added to GLP-1Other conditions: Cushing's Disease, AcromegalyView official trial listing → -
Terminated NCT NCT02072096
A Comparison of Two Treatment Strategies in Older Participants With Type 2 Diabetes Mellitus (T2DM)
Not yet reported Eli Lilly and Company 192 participants Est. completion 2015-10 34 sites Added to GLP-1Type 2 diabetesView official trial listing → -
Completed NCT NCT02089438
DPP-4 Inhibition, Incretins and Islet Function
Not yet reported Lund University 24 participants Est. completion 2017-08 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT02099110
Ertugliflozin and Sitagliptin Co-administration Factorial Study (VERTIS FACTORAL, MK-8835-005)
Not yet reported Merck Sharp & Dohme LLC 1233 participants Est. completion 2016-05-26 Stand-aloneType 2 diabetesView official trial listing → -
Terminated NCT NCT02111096
A Study of LY2409021 in Participants With Type 2 Diabetes Mellitus
Not yet reported Eli Lilly and Company 174 participants Est. completion 2015-09 33 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT02122380
The Effect of Dipeptidyl Peptidase 4 Inhibition on Growth Hormone Secretion in Women With Polycystic Ovarian Syndrome
Not yet reported Vanderbilt University 23 participants Est. completion 2019-08-01 1 site Stand-aloneOther conditions: Polycystic Ovary SyndromeView official trial listing → -
Completed NCT NCT02127047
Effects of Exercise and Inhibition of Dipeptidyl Peptidase-4 on Insulin Secretion in Subjects With Type 1 Diabetes
Not yet reported University Hospital, Basel, Switzerland 24 participants Est. completion 2016-08-05 1 siteOther conditions: Diabetes Mellitus Type 1View official trial listing → -
Completed NCT NCT02130687
Effect of Chronic ACE and DPP4 Inhibition on Blood Pressure
Not yet reported Vanderbilt University 106 participants Est. completion 2020-08 1 site Stand-aloneType 2 diabetes Other conditions: HypertensionView official trial listing → -
Completed NCT NCT02138097
Oral and Non-insulin Injected Hypoglycemic Therapy Utilization Patterns
Boehringer Ingelheim 615067 participants Est. completion 2014-08 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT02147925
Efficacy Study of Liraglutide vs.Sitagliptin vs. Glargine on Liver Fat in T2DM Subjects
Not yet reported Sun Yat-sen University 75 participants Est. completion 2017-04 1 siteOther conditions: Non-alcoholic Fatty Liver DiseaseView official trial listing → -
Completed NCT NCT02172196
Bioavailability of BI 10773 and Sitagliptin in Healthy Male Volunteers
Not yet reported Boehringer Ingelheim 16 participants Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT02173457
Study of Chiglitazar Compare With Sitagliptin in Type 2 Diabetes Patients
Not yet reported Chipscreen Biosciences, Ltd. 740 participants Est. completion 2017-01 37 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT02188186
Therapeutic Efficacy of Triple Combination in Drug-naïve Korean Type 2 Diabetic Patients
Not yet reported Seoul National University Bundang Hospital 200 participants Est. completion 2018-09 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT02192853
Correlation Between Plasma- and Endothelial DPP-4 Activity
Not yet reported University Hospital, Gentofte, Copenhagen 20 participants Est. completion 2014-03 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT02200991
Effect of Lixisenatide on Postprandial Plasma Glucose Compared to Sitagliptin in Combination With Insulin Glargine
Not yet reported Sanofi 136 participants Est. completion 2015-11 20 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT02202161
A Study Investigating Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of GSK2330672 Administered With Metformin to Type 2 Diabetes Patients
Not yet reported GlaxoSmithKline 70 participants Est. completion 2015-01-30 4 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT02226003
Efficacy and Safety of Ertugliflozin (MK-8835/PF-04971729) With Sitagliptin in the Treatment of Participants With Type 2 Diabetes Mellitus (T2DM) With Inadequate Glycemic Control on Diet and Exercise (MK-8835-017)
Not yet reported Merck Sharp & Dohme LLC 291 participants Est. completion 2016-02-23 Stand-aloneType 2 diabetesView official trial listing → -
Terminated NCT NCT02244164
Pathophysiological Study of the Increase in Pancreatic Volume in Type 2 Diabetes Treatments.
Not yet reported Erasme University Hospital 5 participants Est. completion 2023-02-13 1 siteType 2 diabetes Other conditions: Incretinomimetics, PancreasView official trial listing → -
Withdrawn NCT NCT02250794
Metformin and Sitagliptin Therapy for Adult Patients With Type 2 Diabetes Admitted to the General Medical Unit
Not yet reported Rush University Medical Center Est. completion 2015-05 Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT02254291
A Trial Comparing the Safety and Efficacy of Semaglutide Once Weekly Versus Sitagliptin Once Daily in Japanese Subjects With Type 2 Diabetes
Not yet reported Novo Nordisk A/S 308 participants Est. completion 2015-11-11 25 sitesType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT02256189
Sitagliptin and Glucagon Counterregulation
Not yet reported Lund University 28 participants Est. completion 2017-06 1 siteType 2 diabetesView official trial listing → -
Withdrawn NCT NCT02263677
Evaluation of the DPP-4 Inhibitor Sitagliptin in the Treatment of Non-Alcoholic Fatty Liver Disease Using MRI
Not yet reported University of Missouri-Columbia Est. completion 2016-01 1 siteType 2 diabetes Other conditions: Non-alcoholic Fatty Liver DiseaseView official trial listing → -
Completed NCT NCT02284893
Study to Evaluate the Efficacy and Safety of Saxagliptin Co-administered With Dapagliflozin in Combination With Metformin Compared to Sitagliptin in Combination With Metformin in Adult Patients With Type 2 Diabetes Who Have Inadequate Glycemic Control on Metformin Therapy Alone
Not yet reported AstraZeneca 461 participants Est. completion 2016-09-20 79 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT02294084
Sitagliptin and Brown Adipose Tissue
Not yet reported Ingrid Jazet 30 participants Est. completion 2016-12 1 site Stand-aloneOther conditions: Neoplasms, Adipose TissueView official trial listing → -
Status unknown NCT NCT02301806
Effects of Sitaglpitin on Endothelial Function During the OGTT in T2DM
Not yet reported Dokkyo Medical University 30 participants Est. completion 2017-07 2 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT02312063
Dietary Impacts on Glucose-lowering Effects of Sitagliptin in Type 2 Diabetes
Not yet reported Kansai Electric Power Hospital 48 participants Est. completion 2016-05 2 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT02312427
DPP-4 Inhibitor and Serum BNP Level of Diabetic Patients With Congestive Heart Failure
Not yet reported Mitsui Memorial Hospital 10 participants Est. completion 2016-03 1 site Stand-aloneHeart failure Other conditions: Diabetes MellitusView official trial listing → -
Status unknown NCT NCT02315287
Comparison of Lobeglitazone With Pioglitazone as Initial Triple Therapy for Diabetes Management
Not yet reported Seoul National University Bundang Hospital 190 participants Est. completion 2021-12-31 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT02318693
Efficacy of Sitagliptin and Glibenclamide on the Glucose Variability in Japanese Participants With Type 2 Diabetes Mellitus (MK-0431-355)
Not yet reported Merck Sharp & Dohme LLC 53 participants Est. completion 2015-12-15 Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT02324010
Effects of Sitagliptin on Gastric Emptying, Glycaemia and Blood Pressure in Type 2 Diabetes
Not yet reported Royal Adelaide Hospital 14 participants Est. completion 2017-01 1 site Stand-aloneOther conditions: Gastroparesis, Diabetes MellitusView official trial listing → -
Completed NCT NCT02328040
Randomized Trial Comparing Sitagliptin to Placebo in Closed Loop
Not yet reported Albert Einstein College of Medicine 17 participants Est. completion 2016-01 1 siteOther conditions: Diabetes Mellitus, Type 1View official trial listing → -
Completed NCT NCT02330406
Randomized Evaluation of Anagliptin Versus Sitagliptin On Low-density lipoproteiN Cholesterol in Diabetes Trial
Not yet reported Institute for Clinical Effectiveness, Japan 353 participants Est. completion 2019-03 1 siteOther conditions: Dipeptidyl-Peptidase 4 Inhibitors, LDL Cholesterol, Glycosylated Hemoglobin, Diabetes Mellitus, Coronary DiseaseView official trial listing → -
Completed NCT NCT02333591
Effect of Intact GLP-1 (7-36) and GLP-1 Metabolite (9-36) on Coronary and Peripheral Vascular Function in Adults
Not yet reported Mette Zander 25 participants Est. completion 2018-06 1 siteOther conditions: Coronary Microvascular DysfunctionView official trial listing → -
Completed NCT NCT02336659
Influence of Gut Hormones on Food Intake After Roux-en-Y Gastric Bypass Surgery
Not yet reported Hvidovre University Hospital 12 participants Est. completion 2016-06 1 site Stand-aloneOther conditions: Severe ObesityView official trial listing → -
Completed NCT NCT02338921
Triple Combination Therapy in Type 2 Diabetic Patients Who Had Inadequate Glycemic Control With Combination Therapy
Not yet reported Seoul National University Bundang Hospital 78 participants Est. completion 2021-12-31 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT02347501
Dipeptidyl Peptidase-4 Inhibition and Narrow-band Ultraviolet-B Light in Psoriasis (DINUP)
Not yet reported University College Dublin 118 participants Est. completion 2016-12 1 siteOther conditions: PsoriasisView official trial listing → -
Completed NCT NCT02363335
The Role of Phosphodiesterase Inhibitors in Incretin Secretion
Not yet reported National Institute on Aging (NIA) 29 participants Est. completion 2016-09-19 1 site Stand-aloneOther conditions: Healthy VolunteersView official trial listing → -
Terminated NCT NCT02365233
Fatty Liver Study in Patients With Type II Diabetes
Not yet reported The University of Texas Medical Branch, Galveston 5 participants Est. completion 2016-12-31 1 siteOther conditions: Type II Diabetes, Nonalcoholic Fatty LiverView official trial listing → -
Status unknown NCT NCT02368704
Role of Endoplasmic Reticulum Stress in the Pathophysiology of Type 2 Diabetes
Assistance Publique - Hôpitaux de Paris 40 participants Est. completion 2016-11 1 siteType 2 diabetes Other conditions: Endoplasmic Reticulum StressView official trial listing → -
Terminated NCT NCT02373865
Risk of Nocturnal Hypoglycemia and Arrhythmias With Sitagliptin Versus Glimepiride in Patients With Type 2 Diabetes
Not yet reported GWT-TUD GmbH 4 participants Est. completion 2017-01 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT02377388
DPP-4 Inhibitors and Acute Myocardial Infarction:Effects on Platelet Function
Not yet reported University of Sao Paulo General Hospital 74 participants Est. completion 2020-02-28 1 siteCardiovascular diseaseView official trial listing → -
Status unknown NCT NCT02386943
Study on Exploring the Effect of DPP-4 Inhibitors on β-cell Function by Using the Two-step Hyperglycemic Clamp
Not yet reported Shanghai Jiao Tong University School of Medicine 12 participants Est. completion 2015-03 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT02405260
Add Glucokinase Activator to Target A1c
Not yet reported vTv Therapeutics 190 participants Est. completion 2016-09 20 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT02406443
The INDORSE Study: Inhibition of Dipeptidyl Peptidase IV: Outcomes on Renal Sodium Excretion
Not yet reported University Health Network, Toronto 36 participants Est. completion 2017-01 1 site Stand-aloneType 2 diabetesView official trial listing → -
Status unknown NCT NCT02406950
Sitagliptin and Endothelial Dysfunction
Not yet reported Kyunghee University Medical Center 10 participants Est. completion 2015-08 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT02443402
Sitagliptin in Non-Diabetic Patients Undergoing Cardiac Surgery
Not yet reported Emory University 68 participants Est. completion 2016-12 4 sites Stand-aloneCardiovascular diseaseView official trial listing → -
Status unknown NCT NCT02443922
Dynamic Responsiveness of Insulin Secretory Parameters To Sitagliptin and Glimeperide Administration in Type 2 DM
Not yet reported Foundation for the National Institutes of Health 100 participants Est. completion 2015-12 Stand-aloneType 2 diabetesView official trial listing → -
Withdrawn NCT NCT02444364
Effects of DPP-4 Inhibition on Calcium and Bone Metabolism in Type 2 Diabetes Mellitus
Not yet reported University of Missouri-Columbia Est. completion 2016-01 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT02452632
A Study to Assess the Efficacy and Safety of ASP1941 in Subjects With Type 2 Diabetes Mellitus Who Have Inadequate Glycemic Control on Metformin and Sitagliptin
Not yet reported Astellas Pharma Korea, Inc. 143 participants Est. completion 2017-01-05 22 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT02456428
Incretin-based Drugs and the Risk of Heart Failure
Canadian Network for Observational Drug Effect Studies, CNODES 1499650 participants Est. completion 2015-05 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT02475499
Incretin-based Drugs and Pancreatic Cancer
Canadian Network for Observational Drug Effect Studies, CNODES 886172 participants Est. completion 2015-04 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT02476760
Incretin-based Drugs and Acute Pancreatitis
Canadian Network for Observational Drug Effect Studies, CNODES 1417914 participants Est. completion 2015-04 1 siteType 2 diabetesView official trial listing → -
Status unknown NCT NCT02480465
Efficacy and Safety of Lobeglitazone Versus Sitagliptin
Not yet reported Chong Kun Dang Pharmaceutical 248 participants Est. completion 2017-03 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT02493959
Degradation of the Anorexic Hormone Peptide YY
Not yet reported Hvidovre University Hospital 8 participants Est. completion 2015-07 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT02512523
Exploratory Study to Compare the Effects of Tenelia® or Januvia® on Glucose Variability in add-on to Metformin (CGMS Study)
Not yet reported Handok Inc. 39 participants Est. completion 2016-09-26 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT02513771
Sitagliptin for Reducing Inflammation and Immune Activation
Not yet reported Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections 90 participants Est. completion 2017-01-10 16 sitesOther conditions: HIV-1 InfectionView official trial listing → -
Completed NCT NCT02527993
Treatment of Hypoglycemia Following Gastric Bypass Surgery
Not yet reported Zealand University Hospital 11 participants Est. completion 2017-04-08 Stand-aloneOther conditions: Hypoglycemia, Obesity, SurgeryView official trial listing → -
Status unknown NCT NCT02528019
Metabolic and Cardiovascular Effects of Dipeptidyl Peptidase-4 (DPP-4) or Sodium-glucose Co-transporter Type 2 (SGLT2) Inhibitors
Not yet reported Kurume University 100 participants Est. completion 2018-08 1 siteOther conditions: Effects of the DPP-4 Inhibitors or SGLT2 Inhibitors on the Protective Actions for Diabetic ComplicationsView official trial listing → -
Completed NCT NCT02532855
A Study to Assess the Addition of Sitagliptin to Metformin Compared With the Addition of Dapagliflozin to Metformin in Participants With Type 2 Diabetes Mellitus (T2DM) and Mild Renal Impairment Who Have Inadequate Glycemic Control on Metformin With or Without a Sulfonylurea (MK-0431-838)
Not yet reported Merck Sharp & Dohme LLC 614 participants Est. completion 2017-10-10 Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT02536248
Sitagliptin Therapy and Kinetics of Inflammatory Markers
Not yet reported Laval University 20 participants Est. completion 2017-10-31 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT02556918
Sitagliptin for Hyperglycemia in Patients With T2DM Undergoing Cardiac Surgery
Not yet reported Emory University 202 participants Est. completion 2018-11-06 3 sites Stand-aloneOther conditions: HyperglycemiaView official trial listing → -
Completed NCT NCT02564211
Ipragliflozin Add-on Long-term Study in Japanese Participants With Type 2 Diabetes Mellitus on Sitagliptin (MK-0431J-849)
Not yet reported Merck Sharp & Dohme LLC 77 participants Est. completion 2017-03-07 Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT02567994
Tenelia Triple Combination Study
Not yet reported Handok Inc. 201 participants Est. completion 2017-12 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT02576288
Sitagliptin Effects on Arterial Vasculature and Inflammation in Obesity
Not yet reported University of Southern California 21 participants Est. completion 2017-12-31 1 siteOther conditions: Atherosclerosis, InflammationView official trial listing → -
Completed NCT NCT02577003
Double-blind Ipragliflozin Add-on Study in Japanese Participants With Type 2 Diabetes Mellitus Who Have Inadequate Glycemic Control on Sitagliptin (MK-0431J-843)
Not yet reported Merck Sharp & Dohme LLC 143 participants Est. completion 2016-11-25 Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT02577016
Double-blind Sitagliptin Add-on Study in Japanese Participants With Type 2 Diabetes Mellitus Who Have Inadequate Glycemic Control on Ipragliflozin (MK-0431J-842)
Not yet reported Merck Sharp & Dohme LLC 141 participants Est. completion 2016-11-18Type 2 diabetesView official trial listing → -
Completed NCT NCT02607410
Sitagliptin (DPP-4 Inhibitor) and NPH Insulin in Patients With T2D
Not yet reported University of Sao Paulo General Hospital 40 participants Est. completion 2014-07 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT02607865
Efficacy and Long-term Safety of Oral Semaglutide Versus Sitagliptin in Subjects With Type 2 Diabetes
Not yet reported Novo Nordisk A/S 1864 participants Est. completion 2018-03-28 242 sitesType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT02610088
Effect of Dapagliflozin on Vascular Functions in Patients With Type 2 Diabetes Compared to Gliclazide
Not yet reported Seoul National University Bundang Hospital 32 participants Est. completion 2018-09 1 siteOther conditions: DiabetesView official trial listing → -
Completed NCT NCT02623998
Remission Evaluation of a Metabolic Intervention in Type 2 Diabetes With Sitagliptin (REMIT-Sita)
Not yet reported Population Health Research Institute 102 participants Est. completion 2019-11-30 6 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT02628392
A Phase 2 Study of DS-8500a in Japanese Subjects With Type 2 Diabetes Mellitus (T2DM)
Not yet reported Daiichi Sankyo Co., Ltd. 368 participants Est. completion 2016-09 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT02639637
Effect of DPP4 Inhibition on Vasoconstriction
Not yet reported Vanderbilt University 18 participants Est. completion 2017-09 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT02647320
12-Week Study of DS-8500a in Subjects With Type 2 Diabetes Mellitus on Metformin
Not yet reported Daiichi Sankyo 298 participants Est. completion 2017-01-31 58 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT02650427
A Pilot Study to Evaluate the Safety of a 3 Weeks Sitagliptin Treatment in HCC Patients Undergoing Liver Resection
Not yet reported Institut National de la Santé Et de la Recherche Médicale, France 14 participants Est. completion 2018-09 1 site Stand-aloneOther conditions: Hepato CarcinomaView official trial listing → -
Terminated NCT NCT02653131
The Use of DPP-4 Inhibitors in Short Bowel Syndrome
Not yet reported Stanley Dudrick's Memorial Hospital 8 participants Est. completion 2020-04 1 siteOther conditions: Short Bowel SyndromeView official trial listing → -
Completed NCT NCT02653209
TriMaster: Study of a DPP4 Inhibitor, SGLT2 Inhibitor and Thiazolidinedione as Third Line Therapy in Patients With Type 2 Diabetes.
Not yet reported Royal Devon and Exeter NHS Foundation Trust 525 participants Est. completion 2021-01 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT02655757
Effect of Sitagliptin on Progression of Coronary Intermediate Lesion
Not yet reported Li Bo 120 participants Est. completion 2017-03-10 1 siteType 2 diabetes Other conditions: AtherosclerosisView official trial listing → -
Withdrawn NCT NCT02675335
Accelerated Wound Healing in Diabetic Ulcers by Sitagliptin
Not yet reported Wolfgang-Michael Franz Est. completion 2018-03Other conditions: Diabetic FootView official trial listing → -
Completed NCT NCT02683187
DPP4 Inhibition & Beta Cell Function
Not yet reported David D'Alessio, M.D. 40 participants Est. completion 2018-03-16 1 siteOther conditions: HealthyView official trial listing → -
Completed NCT NCT02683525
Sitagliptin for Prevention of Acute Graft Versus-Host Disease After Allogeneic Hematopoietic Stem Cell Transplantation
Not yet reported Sherif S. Farag 37 participants Est. completion 2019-10-01 2 sites Stand-aloneOther conditions: Graft vs Host Disease, Hematopoietic Stem Cell TransplantationView official trial listing → -
Completed NCT NCT02685345
A Study of DS-8500a in Japanese Subjects With Type 2 Diabetes Mellitus Receiving Sitagliptin
Not yet reported Daiichi Sankyo Co., Ltd. 85 participants Est. completion 2016-10 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT02689362
Evogliptin in Type 2 Diabetes Mellitus (EVOLUTION: EVOgLiptina no Diabetes Mellitus TIpO 2)
Not yet reported Eurofarma Laboratorios S.A. 146 participants Est. completion 2018-08-09 10 sites Stand-aloneType 2 diabetesView official trial listing → -
Withdrawn NCT NCT02697253
Mechanisms Underlying Predictors of Success From Obesity Surgery
Not yet reported Icahn School of Medicine at Mount Sinai Est. completion 2021-07-29 1 siteOther conditions: ObesityView official trial listing → -
Completed NCT NCT02738879
Randomized Sitagliptin Withdrawal Study (MK-0431-845)
Not yet reported Merck Sharp & Dohme LLC 746 participants Est. completion 2018-01-30 Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT02741687
Sitagliptin in Non-Diabetic Patients Undergoing General Surgery
Not yet reported Emory University 80 participants Est. completion 2017-04 2 sites Stand-aloneOther conditions: HyperglycemiaView official trial listing → -
Completed NCT NCT02743260
Drug Transporter Interaction Study PHENTRA_2015_KPUK
Not yet reported University of Cologne 24 participants Est. completion 2017-12 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT02749032
Feed-Back Suppression of Meal-Induced Glucagon-like Peptide 1 (GLP-1) Secretion
Not yet reported Michael A. Nauck 24 participants 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT02791490
A Study of the Safety and Efficacy of Sitagliptin Addition During Metformin Up-titration (MK-0431-848)
Not yet reported Merck Sharp & Dohme LLC 458 participants Est. completion 2018-02-01 Stand-aloneType 2 diabetesView official trial listing → -
Status unknown NCT NCT02802644
The Effect of DPP4 Inhibitor on Vasclular Healing
Not yet reported Chung-Ang University 66 participants 6 sites Stand-aloneType 2 diabetes Other conditions: Acute Coronary SyndromeView official trial listing → -
Completed NCT NCT02824874
CKD-396 Drug-drug Interaction Study(A) (CKD-396 DDI(A) P1)
Not yet reported Chong Kun Dang Pharmaceutical 20 participants Est. completion 2016-05 1 siteOther conditions: Diabetes Mellitus, Type IIView official trial listing → -
Completed NCT NCT02827890
CKD-396 Drug-drug Interaction Study(B) (CKD-396 DDI(B) P1)
Not yet reported Chong Kun Dang Pharmaceutical 20 participants Est. completion 2016-05 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT02849080
Efficacy and Safety of Oral Semaglutide Using a Flexible Dose Adjustment Based on Clinical Evaluation Versus Sitagliptin in Subjects With Type 2 Diabetes Mellitus.
Not yet reported Novo Nordisk A/S 504 participants Est. completion 2019-03-27 83 sitesType 2 diabetes Other conditions: DiabetesView official trial listing → -
Active, not recruiting NCT NCT02879409
HbA1c Variability in Type II Diabetes
Not yet reported Weill Cornell Medical College in Qatar 150 participants Est. completion 2026-10-01 1 site Added to GLP-1Type 2 diabetesView official trial listing → -
Status unknown NCT NCT02882477
Treatment of Wolfram Syndrome Type 2 With the Chelator Deferiprone and Incretin Based Therapy
Not yet reported, Not yet reported Hadassah Medical Organization 20 participants Est. completion 2018-12 1 site Stand-aloneOther conditions: Diabetes Mellitus, Iron Metabolism Disorders, Gastroduodenal Ulcer, Optic Atrophy, Sensorineural Hearing Loss, Platelet DysfunctionView official trial listing → -
Status unknown NCT NCT02900417
Evaluation of the Effect of Sitagliptin on Gut Microbiota in Patients With Newly Diagnosed Type 2 Diabetes
Not yet reported Second Affiliated Hospital of Soochow University 9 participants Est. completion 2016-11 Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT02917031
Mechanistic Evaluation of Glucose-lowering Strategies in Patients With Heart Failure
Not yet reported AstraZeneca 348 participants Est. completion 2019-08-23 74 sitesType 2 diabetesHeart failureView official trial listing → -
Completed NCT NCT02920918
Treatment of Diabetes in Patients With Systolic Heart Failure
Not yet reported Virginia Commonwealth University 36 participants Est. completion 2018-09 1 siteHeart failureType 2 diabetesView official trial listing → -
Status unknown NCT NCT02940184
GLP-1 Signaling in Truncally Vagotomized Subjects
Not yet reported University of Copenhagen 24 participants Est. completion 2018-10 1 siteOther conditions: PhysiologyView official trial listing → -
Completed NCT NCT02941445
Weight Maintenance With Dipeptidyl Peptidase 4 (DPP4) Inhibitor Sitagliptin in Combination With Metformin After Liragludite Induced Weight Loss
Not yet reported University Medical Centre Ljubljana 24 participants Est. completion 2016-08 Stand-aloneOther conditions: Polycystic Ovary Syndrome, Body WeightView official trial listing → -
Status unknown NCT NCT02946632
Effectiveness & Tolerability of Novel, Initial Triple Combination Therapy vs Conventional Therapy in Type 2 Diabetes
Not yet reported Korea University Anam Hospital 104 participants Est. completion 2019-12 1 siteOther conditions: Diabetes Mellitus, Type IIView official trial listing → -
Completed NCT NCT02949193
Efficacy and Safety of Evogliptin add-on to Metformin in Patients With type2 Diabetes
Not yet reported Dong-A ST Co., Ltd. 222 participants Est. completion 2015-05 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT02956044
Interaction of Bexagliflozin With Metformin, Glimepiride and Sitagliptin
Not yet reported Theracos 54 participants Est. completion 2017-03 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT03014479
Study of the QOL Evaluation of Trelagliptin in Patients With Type 2 Diabetes Mellitus
Not yet reported Takeda 219 participants Est. completion 2017-10-21 27 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT03061214
Efficacy and Safety of Semaglutide Once-weekly Versus Sitagliptin Once-daily as add-on to Metformin in Subjects With Type 2 Diabetes (SUSTAIN - CHINA MRCT)
Not yet reported Novo Nordisk A/S 868 participants Est. completion 2019-04-15 67 sites Added to GLP-1Type 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT03076112
Efficacy of Ipragliflozin Compared With Sitagliptin in Uncontrolled Type 2 Diabetes With Sulfonylurea and Metformin
Not yet reported Seoul National University Bundang Hospital 170 participants Est. completion 2022-08-31 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT03078049
Characteristics of Patients With Type 2 Diabetes Mellitus Receiving Treatment With Dapagliflozin Versus Sitagliptin: An Analysis of Commercial Claims and Linked Laboratory Data
AstraZeneca 11971 participants Est. completion 2017-05-31 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT03101930
Cardiovascular Effects of GLP-1 Receptor Activation
Not yet reported Vanderbilt University Medical Center 329 participants Est. completion 2021-06-24 1 site Added to GLP-1Prediabetes Other conditions: ObesityView official trial listing → -
Completed NCT NCT03108521
SNP Study of DPP-4 and GLP-1R in Chinese People (Including Diabetes Patients)
Not yet reported Sichuan Provincial People's Hospital 119 participants Est. completion 2018-10-08 1 site Stand-aloneOther conditions: Diabetes MellitusView official trial listing → -
Completed NCT NCT03115099
A Study of LY3325656 in Healthy Participants and Participants With Type 2 Diabetes
Not yet reported Eli Lilly and Company 80 participants Est. completion 2018-04-05 2 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT03115112
Safety and Efficacy of Bexagliflozin Compared to Sitagliptin as Add-on Therapy to Metformin in Type 2 Diabetes Subjects
Not yet reported Theracos 386 participants Est. completion 2018-10-31 56 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT03122041
Sitagliptin Improved Beta Cell Function and Prevented a Conversion Rate to Impaired Glucose Tolerance and Type 2 Diabetes in Metformin Intolerant Obese Women With Polycystic Ovary Syndrome
Not yet reported University Medical Centre Ljubljana 30 participants Est. completion 2016-11 Stand-aloneOther conditions: PCOSView official trial listing → -
Completed NCT NCT03125694
Sitagliptin vs. Pioglitazone as add-on Treatments in Patients With Type 2 Diabetes Uncontrolled on the Full-dose Metformin Plus Sulfonylurea
Not yet reported Tehran University of Medical Sciences 250 participants Est. completion 2017-04-01 1 siteType 2 diabetesView official trial listing → -
Status unknown NCT NCT03180281
Therapies on Newly Diagnosed Type 2 Diabetes Patients With High Glucose Toxicity Which Protect Islet β Cell
Not yet reported First Affiliated Hospital Xi'an Jiaotong University 135 participants Est. completion 2020-01-01 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT03208465
Empagliflozin Versus Sitagliptin Therapy for Improvement of Myocardial Perfusion Reserve in Diabetic Patients With Coronary Artery Disease
Not yet reported CHEOL WHAN LEE, M.D., Ph.D 100 participants Est. completion 2019-08-01 1 siteOther conditions: Diabetes Mellitus, Coronary DiseaseView official trial listing → -
Completed NCT NCT03233178
Measurement of Alanine Aminotransaminase (ALT) Following Initiation of Antidiabetic Agents in Patients With Type 2 Diabetes in a Real-world Clinical Setting: a Retrospective Cohort Study
LMC Diabetes & Endocrinology Ltd. 4000 participants Est. completion 2017-06 1 siteType 2 diabetesMASLD Other conditions: Fatty LiverView official trial listing → -
Completed NCT NCT03267576
An Efficacy Study of Canagliflozin or Sitagliptin to Determine Glucose Variability in Mexican Participants With Type 2 Diabetes Mellitus Inadequately Controlled on Metformin
Not yet reported Janssen Research & Development, LLC 64 participants Est. completion 2018-10-01 5 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT03359590
Sitagliptin and the Risk for Hypoglycaemia in Type 2 Diabetes Patients
Not yet reported Profil Institut für Stoffwechselforschung GmbH 20 participants Est. completion 2019-07-17 1 site Stand-aloneOther conditions: Pharmacological ActionView official trial listing → -
Completed NCT NCT03492580
A Study for Comparison of Canagliflozin Versus Alternative Antihyperglycemic Treatments on Risk of Heart Failure Hospitalization and Amputation for Participants With Type 2 Diabetes Mellitus and the Subpopulation With Established Cardiovascular Disease
Janssen Research & Development, LLC 714582 participants Est. completion 2018-06-25 1 siteType 2 diabetesCardiovascular diseaseView official trial listing → -
Completed NCT NCT03593135
Effect of Apple Cider Vinegar in Type 2 Diabetics
Not yet reported Sheikh Zayed Federal Postgraduate Medical Institute 126 participants Est. completion 2017-11-14 1 site Stand-aloneOther conditions: Randomized Controlled Trial, Diabetes MellitusView official trial listing → -
Status unknown NCT NCT03602638
Effects of a Dipeptidyl Peptidase-4 Inhibitor Sitagliptininsulin on the Progression of Coronary Atherosclerosis in Patients With Type 2 Diabetes
Not yet reported Chinese PLA General Hospital 300 participants Est. completion 2020-12-01 Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT03646721
A Study to Evaluate the Safety, Tolerability, PK and PD of DA-1241 in Healthy Male Subjects and Subjects With T2DM
Not yet reported Dong-A ST Co., Ltd. 108 participants Est. completion 2020-05-07 4 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT03659461
Glucagon-like Peptide-1 Levels, Insulin Resistance and Insulin Sensitivity Index in Type 2 Diabetes Mellitus
Not yet reported National University of Malaysia 174 participants Est. completion 2020-01-31 1 siteType 2 diabetesPrediabetesView official trial listing → -
Completed NCT NCT03717688
The Effects of Neprilysin on Glucagon-like Peptide-1
Not yet reported Nicolai Jacob Wewer Albrechtsen 19 participants Est. completion 2019-05-14 1 siteHeart failure Other conditions: DiabetesView official trial listing → -
Terminated NCT NCT03738878
Mechanism(s) Underlying Hypotensive Response to ARB/NEP Inhibition - Aim 1
Not yet reported Vanderbilt University Medical Center 4 participants Est. completion 2024-12-01 1 siteOther conditions: HypertensionView official trial listing → -
Completed NCT NCT03790839
Drug Interaction Study Between Dorzagliatin and Sitagliptin
Not yet reported Hua Medicine Limited 15 participants Est. completion 2019-08-30 1 site Stand-aloneOther conditions: PatientsView official trial listing → -
Status unknown NCT NCT03804411
Prognostic Predictors of Response to Hypoglycemic Therapy
Not yet reported Federal State Budgetary Institution, V. A. Almazov Federal North-West Medical Research Centre, of the Ministry of Health 800 participants Est. completion 2020-05 1 siteType 2 diabetesView official trial listing → -
Withdrawn NCT NCT03813316
Approaches To Therapy Escalation In T2D
Not yet reported LMC Diabetes & Endocrinology Ltd. Est. completion 2019-09-18 Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT03845179
GA 6: The Blood Glucose-lowering Effect of Glucose-dependent Insulinotropic Polypeptide
Not yet reported University Hospital, Gentofte, Copenhagen 12 participants Est. completion 2020-02-28 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT03851341
Pharmacokinetic Characteristics of GLH1SM Extended Release Tablets in Healthy Volunteers
Not yet reported GL Pharm Tech Corporation 30 participants Est. completion 2019-01-18 1 siteOther conditions: HealthyView official trial listing → -
Completed NCT NCT03893526
Effect of Neprilysin on Glucagon-Like Peptide-1 in Patients With Type 2 Diabetes
Not yet reported University of Copenhagen 12 participants Est. completion 2021-03-01 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT03918148
Gliflozins and Cardiovascular Risk Factors in Type 2 Diabetes (GIOIA)
University of Campania Luigi Vanvitelli 1150 participants Est. completion 2023-12-31 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT03927170
Pharmacokinetic Characteristics of GLH1SM Extended Release Tablets in Healthy Volunteers(Fed)
Not yet reported GL Pharm Tech Corporation 25 participants Est. completion 2019-10-23 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT03936062
Replication of the TECOS Diabetes Trial in Healthcare Claims
Brigham and Women's Hospital 349476 participants Est. completion 2021-02-18 1 siteOther conditions: DiabetesView official trial listing → -
Completed NCT NCT03939624
Sodium-glucose Cotransporter 2 (SGLT2) Inhibitors and Risk of Cardiovascular Events
Canadian Network for Observational Drug Effect Studies, CNODES 419734 participants Est. completion 2019-10-01 1 siteType 2 diabetesCardiovascular diseaseHeart failure Other conditions: Cardiovascular Death, All-Cause MortalityView official trial listing → -
Completed NCT NCT03959501
Metabolic Responses of Dapagliflozin vs Sitagliptin in T2DM Patients Inadequately Controlled With Insulin Therapy
Not yet reported The University of Hong Kong 60 participants Est. completion 2020-10-16 1 siteType 2 diabetes Other conditions: KetonemiaView official trial listing → -
Completed NCT NCT04017221
Safety of Sodium-glucose Cotransporter 2 (SGLT2) Inhibitors Among Patients With Type 2 Diabetes
Canadian Network for Observational Drug Effect Studies, CNODES 1249636 participants Est. completion 2019-12-01 1 siteType 2 diabetes Other conditions: Urosepsis, Diabetic Ketoacidosis, Lower Extremity AmputationView official trial listing → -
Completed NCT NCT04017832
A Research Study Comparing a New Medicine Oral Semaglutide to Sitagliptin in People With Type 2 Diabetes
Not yet reported Novo Nordisk A/S 1441 participants Est. completion 2021-10-27 93 sites Added to GLP-1Type 2 diabetesView official trial listing → -
Completed NCT NCT04061473
Involvement of Dipeptidyl Peptidase-4 and Sodium-glucose Co-transporter-2 in Extrapancreatic Glucagon Secretion
Not yet reported University Hospital, Gentofte, Copenhagen 20 participants Est. completion 2019-08-20 1 siteOther conditions: Diabetes After Total PancreatectomyView official trial listing → -
Completed NCT NCT04149067
Study of Real-world Evidence With SGLT2i (Dapagliflozin) and DPP4i (Sitagliptin) in Type 2 Diabetes Patients in Spain
Fundación Pública Andaluza para la gestión de la Investigación en Sevilla 1080 participants Est. completion 2019-03-15 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT04161430
A Study to Evaluate the Efficacy and Safety of DBPR108 100 mg in Type 2 Diabetes Mellitus Patients
Not yet reported CSPC ZhongQi Pharmaceutical Technology Co., Ltd. 766 participants Est. completion 2022-06-27 2 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT04192292
Study of Sulphonylurea Synergy With DPP4 Inhibitors
Not yet reported University of Dundee 30 participants Est. completion 2020-12-02 1 site Stand-aloneType 2 diabetesView official trial listing → -
Status unknown NCT NCT04268563
Comparing the Effect of Sitagliptin/Metformin and Metformin in PCOS Patients
Not yet reported, Not yet reported Shahid Beheshti University of Medical Sciences 80 participants Est. completion 2021-07-30 1 site Stand-aloneOther conditions: Polycystic Ovary Syndrome, Infertility, ARTView official trial listing → -
Completed NCT NCT04271189
Managing DIabetes Remission After Combined Therapy in EarLy Stage of DiabetEs
Not yet reported Azienda Ospedaliero-Universitaria di Parma 108 participants Est. completion 2024-12-31 1 site Stand-aloneType 2 diabetesView official trial listing → -
Status unknown NCT NCT04287387
Response of Gut Microbiota in Type 2 Diabetes to Hypoglycemic Agents
Not yet reported Peking Union Medical College Hospital 180 participants Est. completion 2021-03-02 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT04295005
A Study Based on Data From German Sick Funds That Looks at the Costs of Treatment of Type-2 Diabetic Patients With Empagliflozin vs. DPP-4 Inhibitors vs. GLP-1 Receptor Agonists
Boehringer Ingelheim 24500 participants Est. completion 2021-09-30 1 siteType 2 diabetesView official trial listing → -
Status unknown NCT NCT04298684
Efficacy of Metformin Versus Sitagliptin on Benign Thyroid Nodules in Type 2 Diabetes
Not yet reported Centre Hospitalier Universitaire de la Guadeloupe 90 participants Est. completion 2024-07-01 4 sites Stand-aloneType 2 diabetes Other conditions: Thyroid Nodule (Benign)View official trial listing → -
Completed NCT NCT04304261
Effects of SGLT2i on the Cognitive Function in T2DM Patient (ESCDP)
Not yet reported Third Military Medical University 100 participants Est. completion 2024-04-30 1 site Stand-aloneType 2 diabetes Other conditions: Cognitive Functions ConfusionView official trial listing → -
Active, not recruiting NCT NCT04323189
Effects of Sitagliptin in Individuals With Genetically Decreased DPP4
Not yet reported University of Pennsylvania 20 participants Est. completion 2026-02-28 1 siteType 2 diabetesHeart failure Other conditions: Genetics DiseaseView official trial listing → -
Status unknown NCT NCT04365517
The Effect of Sitagliptin Treatment in COVID-19 Positive Diabetic Patients
Not yet reported University of Milan 170 participants Est. completion 2022-12-30 1 siteType 2 diabetesChronic kidney disease Other conditions: Covid19View official trial listing → -
Completed NCT NCT04382794
Sitagliptin Treatment in Diabetic COVID-19 Positive Patients
University of Milan 338 participants Est. completion 2020-06-15 6 sitesOther conditions: Covid19View official trial listing → -
Completed NCT NCT04409795
Oral Hypoglycemic Therapy for Monogenic Variant Carriers of the Joslin Medalist Study
Not yet reported, Not yet reported Joslin Diabetes Center 3 participants Est. completion 2024-12-31 1 siteOther conditions: Type 1 Diabetes, Monogenic DiabetesView official trial listing → -
Status unknown NCT NCT04448587
Sitagliptin for the Treatment of Grade 3-4 and Refractory Acute Graft-versus-host Disease
Not yet reported Rabin Medical Center 10 participants Est. completion 2021-12-31 1 site Stand-aloneOther conditions: Graft Vs Host DiseaseView official trial listing → -
Status unknown NCT NCT04495881
Sitagliptin for the Treatment of Type 2 Diabetes
Not yet reported Beijing Chao Yang Hospital 50 participants Est. completion 2025-09-01 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT04801199
Effect of CPL-2009-0031 in the Treatment of Patients With Uncontrolled Type 2 Diabetes Mellitus
Not yet reported Cadila Pharnmaceuticals 355 participants Est. completion 2021-02-11 12 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT04810507
MAGE of Anagliptin Compared With Sitagliptin With Type 2 Diabetes Mellitus
Not yet reported JW Pharmaceutical 89 participants Est. completion 2021-01-05 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT04877106
Bioequivalence of Sitagliptin Phosphate/Metformin Hydrochloride Tablets in Healthy Chinese Subjects
Not yet reported The Affiliated Hospital of Qingdao University 48 participants Est. completion 2018-07-31 1 site Stand-aloneOther conditions: Healthy SubjectsView official trial listing → -
Completed NCT NCT04882813
Replication of the DAPA-CKD (Chronic Kidney Disease) Trial in Healthcare Claims Data
Brigham and Women's Hospital 87727 participants Est. completion 2021-06-11 1 siteChronic kidney diseaseView official trial listing → -
Completed NCT NCT04916093
Safety and Efficacy of Antidiabetic Drugs in Recently Diagnosed Patients With Type 2 Diabetes
Not yet reported Beni-Suef University 60 participants Est. completion 2020-12-15 1 site Stand-aloneType 2 diabetesView official trial listing → -
Status unknown NCT NCT04982705
IDG-16177 for the Evaluation of Its Safety and Pharmacokinetics
Not yet reported IlDong Pharmaceutical Co Ltd 94 participants Est. completion 2022-12-30 1 siteType 2 diabetesView official trial listing → -
Status unknown NCT NCT05032001
ORAL ANTIDIABETICS EFFECT ON VISCERAL FAT
Not yet reported Metabolic Research Unit 30 participants Est. completion 2022-08-01 1 siteType 2 diabetes Other conditions: Abdominal ObesityView official trial listing → -
Completed NCT NCT05035849
Comparison of the FGM Profiles in Patients of Type 2 Diabetes Treated With Sitagliptin and Acarbose
Not yet reported Nanjing First Hospital, Nanjing Medical University 60 participants Est. completion 2021-05-05 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT05042505
Effect of Dapagliflozin vs Sitagliptin on Liver Fat Accumulation and Body Composition in Patients With Diabetes Mellitus and Liver Transplantation
Not yet reported Medanta, The Medicity, India 100 participants Est. completion 2026-02-27 1 siteOther conditions: Diabetes Mellitus, Liver Transplant; ComplicationsView official trial listing → -
Completed NCT NCT05099198
Replication of the GRADE Diabetes Trial in Healthcare Claims Data
Brigham and Women's Hospital 6403 participants Est. completion 2021-08-01 1 siteOther conditions: DiabetesView official trial listing → -
Completed NCT NCT05149365
Sitagliptin for Prevention of aGVHD After Alternative Donor Transplation
Not yet reported The First Affiliated Hospital of Soochow University 190 participants Est. completion 2025-06-16 1 site Stand-aloneOther conditions: Acute-graft-versus-host Disease, Allogeneic Hematopoietic Stem Cell TransplantationView official trial listing → -
Status unknown NCT NCT05161429
BESTMED: Observational Evaluation of Second Line Therapy Medications in Diabetes
Brigham and Women's Hospital 550000 participants Est. completion 2024-06-30 5 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT05167513
Monitoring Parameters Beyond Glycemic Control: Impact of Sitagliptin on Quality of Life in Type 2 Diabetes Patients
Not yet reported Getz Pharma 188 participants Est. completion 2022-04-28 1 site Stand-aloneType 2 diabetes Other conditions: Quality of Life, Metformin+SitagliptinView official trial listing → -
Enrolling by invitation NCT NCT05195944
Semaglutide vs Sitagliptin
Not yet reported University Health Network, Toronto 58 participants Est. completion 2026-12 1 site Added to GLP-1MASHMASLD Other conditions: Liver Transplant; Complications, Diabetes MellitusView official trial listing → -
Status unknown NCT NCT05214235
A Clinical Study on the Effect of Hypoglycemic Drugs on the Prognosis of Spinal Surgery in Diabetic Patients
Xijing Hospital 124 participants Est. completion 2024-02-29 1 siteOther conditions: Diabetes Mellitus, Spinal DiseasesView official trial listing → -
Not yet recruiting NCT NCT05219409
Effects of Sitagliptin in Relatives of T1D Patients
Not yet reported, Not yet reported University of Milan 70 participants Est. completion 2027-12 1 siteOther conditions: Type 1 DiabetesView official trial listing → -
Active, not recruiting NCT NCT05220917
Comparative Effectiveness and Safety of Four Second Line Pharmacological Strategies in Type 2 Diabetes Study
Brigham and Women's Hospital 781430 participants Est. completion 2027-09-30 1 siteType 2 diabetes Other conditions: Cardiovascular Events, Renal DiseaseView official trial listing → -
Completed NCT NCT05236998
A Pharmacokinetic Study of SID1903 (FDC of Dapagliflozin and Sitagliptin) in Healthy Adult Volunteers
Not yet reported SK Chemicals Co., Ltd. 45 participants Est. completion 2021-12-31 1 site Stand-aloneOther conditions: Healthy SubjectsView official trial listing → -
Completed NCT NCT05266404
Phase 1 Bioequivalence Study of Dapagliflozin/Sitagliptin FDC vs Loose Combination of Single Components
Not yet reported AstraZeneca 46 participants Est. completion 2022-05-31 1 site Stand-aloneType 2 diabetesView official trial listing → -
Status unknown NCT NCT05347459
Cognitive Protective Effect of Newer Antidiabetic Drugs
Alexandria University 100 participants Est. completion 2023-12 1 siteType 2 diabetesView official trial listing → -
Status unknown NCT NCT05353673
The Combination of Sitagliptin and Danazol as the Treatment of Steroid-resistant/Relapse Immune Thrombocytopenia
Not yet reported Peking University People's Hospital 120 participants Est. completion 2023-02-01 1 siteOther conditions: Immune Thrombocytopenia, Blood Coagulation Disorders, Thrombocytopenia, Physiological Effects of DrugsView official trial listing → -
Completed NCT NCT05359341
Which is Better to Start With DPP-4 Inhibitors or SGLT-2 Inhibitors in Egyptian Diabetic Patients?
Not yet reported Sadat City University 175 participants Est. completion 2022-01-10 1 siteOther conditions: Diabete Type 2View official trial listing → -
Completed NCT NCT05367063
Canagliflozin and Myocardial Fibrosis
Not yet reported Shanghai Zhongshan Hospital 45 participants Est. completion 2025-03-20 1 siteType 2 diabetes Other conditions: Cardiovascular RiskView official trial listing → -
Status unknown NCT NCT05386186
The Effect of Glimepiride Compared With Sitagliptin as an add-on Therapy to Metformin in Severe Insulin Deficiency Diabetes
Not yet reported Peking University People's Hospital 192 participants Est. completion 2024-03-31 1 siteType 2 diabetes Other conditions: Severe Insulin Deficient DiabetesView official trial listing → -
Completed NCT NCT05403281
A Pharmacokinetic Study of DW6012 (FDC of Dapagliflozin and Sitagliptin) in Healthy Adult Volunteers
Not yet reported Dong Wha Pharmaceutical Co. Ltd. 41 participants Est. completion 2022-03-28 1 site Stand-aloneOther conditions: Healthy SubjectsView official trial listing → -
Completed NCT NCT05453786
A Pharmacokinetic Study of SID1903 (FDC of Dapagliflozin and Sitagliptin) in Healthy Adult Volunteers
Not yet reported SK Chemicals Co., Ltd. 51 participants Est. completion 2022-08-11 1 siteOther conditions: Healthy SubjectsView official trial listing → -
Completed NCT NCT05480007
Non-alcoholic Fatty Liver Disease and Its Treatment
Not yet reported Shanghai 10th People's Hospital 68 participants Est. completion 2018-12-01 Stand-aloneMASLDView official trial listing → -
Completed NCT NCT05549570
Comparative Bioavailability Study of Metformin/Sitagliptin 850 mg/50 mg Tablets in Healthy Male and Female Volunteers
Not yet reported Galenicum Health 26 participants Est. completion 2017-11-01 1 site Stand-aloneType 2 diabetes Other conditions: BioequivalenceView official trial listing → -
Completed NCT NCT05549583
Comparative Bioavailability Study of Sitagliptin/Metformin 50 mg/1000 mg Tablets in Healthy Male and Female Volunteers
Not yet reported Galenicum Health 26 participants Est. completion 2018-04-25 1 site Stand-aloneType 2 diabetes Other conditions: BioequivalenceView official trial listing → -
Completed NCT NCT05556291
Combination of Ertugliflozin And Sitagliptin Efficacy, Safety & Tolerability (CEASE Diabetes) Study
Getz Pharma 190 participants Est. completion 2024-12-01 3 sitesOther conditions: Efficacy, Safety, TolerabilityView official trial listing → -
Completed NCT NCT05579119
SITAgliptin Plus GLARgine to Glycemic Control in the Hospital Setting (SITAGLAR-H)
Not yet reported Hospital de Especialidades, Centro Medico Nacional "La Raza", Instituto Mexicano del Seguro Social 76 participants Est. completion 2023-08-24 1 site Stand-aloneType 2 diabetesView official trial listing → -
Status unknown NCT NCT05667220
Sitagliptin in Combination With Beidougen Capsule for Type 2 Diabetes
Not yet reported Beijing Chao Yang Hospital 20 participants Est. completion 2023-12-31 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT05725798
Perioperative Sitagliptin Medication for Reduction of the Inflammatory Response Associated With Cardiopulmonary Bypass
University Hospital Muenster 20 participants Est. completion 2023-08-01 1 siteOther conditions: Systemic Inflammatory Response SyndromeView official trial listing → -
Completed NCT NCT05768945
Data Analysis for Drug Repurposing for Effective Alzheimer's Medicines (DREAM)- Semaglutide v DPP4 Inhibitors
Brigham and Women's Hospital 742670 participants Est. completion 2023-12-31 1 siteOther conditions: DiabetesView official trial listing → -
Completed NCT NCT05798715
Bioequivalence Study of of Metformin HCl From Gleptomet 50/1000 mg F.C.Tablets (EVA Pharma, Egypt) and Janumet 50/1000 mg F.C.Tablets (Merck Sharp & Dohme, The Netherlands)
Not yet reported Genuine Research Center, Egypt 30 participants Est. completion 2023-01-13 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT05822674
Variable Effects of Anti-diabetics on Stress Hyperglycemia Ratio
University of Diyala 80 participants Est. completion 2023-02-01 1 siteType 2 diabetesView official trial listing → -
Withdrawn NCT NCT05833958
Polypill Versus Metformin in New Onset Type 2 Diabetes
Not yet reported George Medicines PTY Limited Est. completion 2025-09Type 2 diabetesView official trial listing → -
Status unknown NCT NCT05870462
Semaglutide and Vascular Regeneration
Not yet reported Canadian Medical and Surgical Knowledge Translation Research Group 100 participants Est. completion 2024-12 2 sites Added to GLP-1Cardiovascular diseaseType 2 diabetes Other conditions: Atherosclerosis, ObesityView official trial listing → -
Withdrawn NCT NCT05895201
High-Dose Post-Transplant Cyclophosphamide, Bortezomib, and Sitagliptin for the Prevention of GVHD
Not yet reported, Not yet reported Indiana University Est. completion 2025-12 1 site Stand-aloneOther conditions: Bone Marrow Transplant Complications, Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, Adult, Myelodysplastic Syndromes, Chronic Myelomonocytic LeukemiaView official trial listing → -
Completed NCT NCT05900531
A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of K-757 in Healthy Overweight/Obese Volunteers
Not yet reported Kallyope Inc. 60 participants Est. completion 2023-05-31 1 site Stand-aloneOther conditions: ObesityView official trial listing → -
Enrolling by invitation NCT NCT05947825
Sitagliptin Combined With Gemcitabine and Albumin-bound Paclitaxel in PDAC Patients
Not yet reported Tianjin Medical University Cancer Institute and Hospital 30 participants Est. completion 2026-09 1 site Stand-aloneOther conditions: PDAC - Pancreatic Ductal AdenocarcinomaView official trial listing → -
Completed NCT NCT05972928
Effect of Sitagliptin on Polycystic Ovarian Syndrome Patients
Not yet reported, Not yet reported Beni-Suef University 80 participants Est. completion 2025-07-31 1 site Stand-aloneOther conditions: Polycystic Ovary SyndromeView official trial listing → -
Completed NCT NCT06054815
Study to Evaluate the Efficacy and Safety of DA-1241 in Subjects With Presumed NASH
Not yet reported NeuroBo Pharmaceuticals Inc. 109 participants Est. completion 2024-10-30 18 sites Stand-aloneOther conditions: NON-ALCOHOLIC STEATOHEPATITISView official trial listing → -
Completed NCT NCT06115460
The Impact of Sitagliptin as an Add on Therapy With Closed Loop Control in Adolescents With Diabetic Nephropathy
Not yet reported Ain Shams University 46 participants Est. completion 2023-06-15 1 siteChronic kidney diseaseView official trial listing → -
Completed NCT NCT06124495
Bioequivalence Study of Sitagliptin Hydrochloride / Metformin Hydrochloride Extended-release Film Coated Tablets 50 mg /500 mg (FDC) in Healthy Adult Male and Female Subjects Under Fasting Conditions.
Not yet reported Galenicum Health 58 participants Est. completion 2023-02-13 1 site Stand-aloneType 2 diabetes Other conditions: BioequivalenceView official trial listing → -
Completed NCT NCT06124547
Bioequivalence Study of Sitagliptin Hydrochloride / Metformin Hydrochloride Extended-release Film Coated Tablets 50 mg /500 mg (FDC) in Healthy Adult Male and Female Subjects Under Fed Conditions.
Not yet reported Galenicum Health 48 participants Est. completion 2023-02-13 1 site Stand-aloneType 2 diabetes Other conditions: BioequivalenceView official trial listing → -
Completed NCT NCT06124560
Bioequivalence Study of Sitagliptin Hydrochloride / Metformin Hydrochloride Extended-release Film Coated Tablets 100 mg /1000 mg (FDC) in Healthy Adult Male and Female Subjects Under Fasting Conditions.
Not yet reported Galenicum Health 58 participants Est. completion 2022-11-07 1 siteType 2 diabetes Other conditions: BioequivalenceView official trial listing → -
Completed NCT NCT06124573
Bioequivalence Study of Sitagliptin Hydrochloride / Metformin Hydrochloride Extended-release Film Coated Tablets 100 mg /1000 mg (FDC) in Healthy Adult Male and Female Subjects Under Fed Conditions.
Not yet reported Galenicum Health 48 participants Est. completion 2022-11-21 1 site Stand-aloneType 2 diabetes Other conditions: BioequivalenceView official trial listing → -
Status unknown NCT NCT06147518
To Compare the Safety and Efficacy of Dapagliflozin Plus Metformin Versus Sitagliptin Plus Metformin for Treatment of Diabetes in Patients With Compensated and Stable Decompensated Cirrhosis
Not yet reported Institute of Liver and Biliary Sciences, India 240 participants Est. completion 2024-12-31 1 siteOther conditions: Compensated Cirrhosis, Decompensated CirrhosisView official trial listing → -
Completed NCT NCT06148259
SGLT Inhibitors Versus DDP4 Inhibitors and Prostate in Patient With Diabetes
Not yet reported Kasr El Aini Hospital 57 participants Est. completion 2022-09-13 2 sitesOther conditions: Diabetes Mellitus, Prostatic HyperplasiaView official trial listing → -
Completed NCT NCT06187285
Efficay and Safety of Empagliflozin Versus Sitagliptin for the In-patient Management of Hyperglycemia
Not yet reported Medanta, The Medicity, India 220 participants Est. completion 2025-06-01 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT06204107
A Clinical Trial to Evaluate the Food Effect on Pharmacokinetic Profiles and Safety of CKD-379
Not yet reported Chong Kun Dang Pharmaceutical 28 participants Est. completion 2023-12-06 1 site Stand-aloneType 2 diabetesView official trial listing → -
Status unknown NCT NCT06233201
Sitagliptin and Metformin Hydrochloride Tablets 50 mg/500 mg Relative to Originator
Not yet reported Bio-innova Co., Ltd 34 participants Est. completion 2024-07-28Other conditions: Healthy SubjectsView official trial listing → -
Status unknown NCT NCT06233240
Sitagliptin and Metformin Hydrochloride Tablets 50 mg/1000 mg Relative to Originator
Not yet reported Bio-innova Co., Ltd 34 participants Est. completion 2024-06-12 Stand-aloneOther conditions: Healthy SubjectsView official trial listing → -
Completed NCT NCT06263673
Anti-Diabetic Medications to Fight PD and LBD
Not yet reported Mayo Clinic 18 participants Est. completion 2025-01-08 1 site Stand-aloneOther conditions: Lewy Body Dementia, Parkinson DiseaseView official trial listing → -
Status unknown NCT NCT06449235
Real-World Evaluation of Omarigliptin for Type 2 Diabetes Meliitus in Bangladesh
Not yet reported Bangladesh Institute of Research and Rehabilitation in Diabetes, Endocrine and Metabolic Disorders 938 participants Est. completion 2025-06 1 siteOther conditions: Type2diabetesView official trial listing → -
Status unknown NCT NCT06515652
To Compare the Effects of Herbal Medicines With Traditional Allopathic Medicines in Cases of Patients With Metabolic Syndrome
Not yet reported Hamdard University 200 participants Est. completion 2024-08-30 1 siteMetabolic syndromeView official trial listing → -
Withdrawn NCT NCT06560333
iSGLT2 Inhibitor and a iDPP -4 Inhibitor in Treatment of Type 2 Diabetes Mellitus in Patients Treated With Metformin (TRIAD)
Not yet reported Eurofarma Laboratorios S.A. Est. completion 2029-02-28 1 siteType 2 diabetesView official trial listing → -
Status unknown NCT NCT06570980
Comparative Analysis of Cost-effectiveness Between Sulfonylureas and DPP4 Inhibitors in Combination With Metformin in Treatment of Type 2 Diabetic Patients : A Retrospective, Observational Study.
Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh 200 participants Est. completion 2024-08-30 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT06613750
Comparative Study of Sitagliptin and Gliclazide With Metformin in Type 2 Diabetes Patients With Glucotoxicity
Not yet reported Zhibin Xu 129 participants Est. completion 2024-07-01 1 site Stand-aloneType 2 diabetes Other conditions: GlucotoxicityView official trial listing → -
Completed NCT NCT06659679
Emulating the PIONEER6 Diabetes Trial Using Healthcare Claims
Brigham and Women's Hospital 26126 participants Est. completion 2025-03-06 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT06659718
Emulation of the SOUL Diabetes Trial in Healthcare Claims
Brigham and Women's Hospital 43650 participants Est. completion 2025-02-13 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT06659744
Emulation of the SUSTAIN6 Diabetes Trial Using Healthcare Claims
Brigham and Women's Hospital 158310 participants Est. completion 2025-03-06 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT06759922
Glimepiride, Empagliflozin, and Sitagliptin With Metformin for Type 2 Diabetes
Not yet reported Bahria University 172 participants Est. completion 2025-06-30 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT06770894
DPP4-Inhibitors and Bone Metabolism in Diabetes
Not yet reported Azienda Policlinico Umberto I 132 participants Est. completion 2024-01-24 1 site Stand-aloneType 2 diabetes Other conditions: Osteoporosis, Bone Loss, PostmenopausalView official trial listing → -
Not yet recruiting NCT NCT06813014
Pharmacogenetics of Response to Sitagliptin (PRS)
Not yet reported University of Maryland, Baltimore 400 participants Est. completion 2032-12 1 site Stand-aloneOther conditions: DiabetesView official trial listing → -
Completed NCT NCT06851962
Impact of Pharmacogenetic-Guided Treatment on Type 2 Diabetes.
Not yet reported Fundación para la Investigación del Hospital Clínico de Valencia 92 participants Est. completion 2026-06-30 3 sites Added to GLP-1Type 2 diabetesView official trial listing → -
Completed NCT NCT06914102
Emulation of the STEP-HFpEF DM Heart Failure Trial in Healthcare Claims Data
Brigham and Women's Hospital 58387 participants Est. completion 2025-06-01 1 siteType 2 diabetesHeart failureView official trial listing → -
Completed NCT NCT06914154
Emulation of the SUMMIT Heart Failure Trial in Healthcare Claims Data
Brigham and Women's Hospital 11265 participants Est. completion 2025-06-01 1 siteType 2 diabetesHeart failureView official trial listing → -
Completed NCT NCT06952231
Effect of Sitagliptin and Empagliflozin in Combination With Metformin on Hs-CRP Levels in Patients With Type 2 Diabetes Mellitus
Not yet reported University of Lahore 50 participants Est. completion 2025-01-05 1 siteOther conditions: Diabetes MellitusView official trial listing → -
Enrolling by invitation NCT NCT07073768
Comparison Between Efficacy of Trelagliptin and Sitagliptin in Type II Diabetic Patients
Not yet reported Khyber Medical College, Peshawar 126 participants Est. completion 2026-12-30 1 site Stand-aloneType 2 diabetes Other conditions: Glycemic Control for Diabetes MellitusView official trial listing → -
Completed NCT NCT07076056
Clinical Trial to Evaluate the Efficacy and Safety of DW1026C1 or DW1026C2
Not yet reported Daewon Pharmaceutical Co., Ltd. 230 participants Est. completion 2024-06-19 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT07083232
The Effect of Sitagliptin, Pioglitazone and Dapagliflozine on Myocardial Infarction in Diabetic Rats
Not yet reported Al-Azhar University 50 participants Est. completion 2024-11-30 1 site Stand-aloneCardiovascular disease Other conditions: DiabeticView official trial listing → -
Completed NCT NCT07096063
Comparative Effectiveness of Tirzepatide and Semaglutide in Individuals at Cardiovascular Risk
Brigham and Women's Hospital 887132 participants Est. completion 2025-07-15 1 siteType 2 diabetes Other conditions: Overweight, Cardiovascular (CV) RiskView official trial listing → -
Not yet recruiting NCT NCT07108985
Effect of Add-on SGLT2i, TZD, or Combination Therapy in Type 2 Diabetes Patients on DPP4 Inhibitors
Not yet reported Yonsei University 100 participants Est. completion 2030-08-31 1 site Stand-aloneType 2 diabetes Other conditions: Hyperglycemia, Insulin ResistanceView official trial listing → -
Completed NCT NCT07172269
Mangosteen Supplement as Adjuvant Therapy With Sitagliptin/Metformin in Iraqi Patients With Type 2 Diabetes
Not yet reported Mais Qais Hbeeb 58 participants Est. completion 2025-05-26 1 siteType 2 diabetes Other conditions: Diabete Mellitus, Dyslipidemia in Patients With Diabetes Mellitus, Insulin ResistanceView official trial listing → -
Active, not recruiting NCT NCT07188545
Using Secondary Data to Evaluate Sex-based Heterogeneity of GLP-1 Agonists and SGLT2 Inhibitors on Cardiovascular-Kidney-Metabolic Health (CKMH) Outcomes in Real-world Settings (DASH-CKMH)
Ohio State University 23280000 participants Est. completion 2029-06-30 1 siteMetabolic syndromeView official trial listing → -
Completed NCT NCT07203677
Comparative Effectiveness of Tirzepatide Versus Sitagliptin in Individuals at Cardiovascular Risk (TIRZSITA-CVOT)
Brigham and Women's Hospital 49065 participants Est. completion 2025-10-15 1 siteType 2 diabetesCardiovascular diseaseView official trial listing → -
Not yet recruiting NCT NCT07365358
Evaluate the Efficacy and Safety of Empagliflozin or Glimepiride Combination Therapy in Type 2 Diabetes Mellitus Patients
Not yet reported Chong Kun Dang Pharmaceutical 200 participants Est. completion 2027-08 1 siteOther conditions: Diabete Type 2View official trial listing → -
Active, not recruiting NCT NCT07390110
Comparative Effectiveness of Oral Semaglutide vs Sitagliptin Among Individuals With Heart Failure With Preserved Ejection Fraction (STEP-HFpEF DM ORAL)
Brigham and Women's Hospital 25664 participants Est. completion 2026-06-30 1 siteType 2 diabetesHeart failureView official trial listing → -
Completed NCT NCT07417618
INcreTin-based thERapies for Cardiovascular Event PrevenTion in Patients With and Without ASCVD (INTERCEPT-ASCVD)
Brigham and Women's Hospital 60000 participants Est. completion 2026-06-19 1 siteType 2 diabetesCardiovascular disease Other conditions: OverweightView official trial listing → -
Completed NCT NCT07417631
Emulation of the REWIND Cardiovascular Outcomes Trial in Healthcare Claims Data.
Brigham and Women's Hospital 300000 participants Est. completion 2026-06-15 1 siteType 2 diabetesView official trial listing → -
Not yet recruiting NCT NCT07436663
Comparative Study Between (SGLT-2i) and (DPP-4i) in the Prevention of DIC
Not yet reported Tanta University 150 participants Est. completion 2027-12-01Other conditions: Breast CancerView official trial listing → -
Completed NCT NCT07439536
Dose Optimization of Sitagliptin and Duloxetine in Diabetic Cirrhosis
Not yet reported Kafrelsheikh University 64 participants Est. completion 2025-10-01 1 site Stand-aloneOther conditions: Liver Cirrhosis With DiabetesView official trial listing → -
Enrolling by invitation NCT NCT07452913
Metformin, Empagliflozin With Sitagliptin vs Linagliptin in Type 2 Diabetes
Not yet reported Bahria University 110 participants Est. completion 2026-06-30 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT07531108
Effects of Empagliflozin-Metformin, Sitagliptin-Metformin, and Metformin on Adipokines in Type 2 Diabetes
Not yet reported Hawler Medical University 186 participants Est. completion 2025-11-27 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT07567781
A Phase 1 Study to Assess the Effect of ABBV-722 on Midazolam, Digoxin, Pitavastatin, Metformin, and Sitagliptin Drug Levels in Healthy Adults.
Not yet reported AbbVie 12 participants Est. completion 2026-07-21 1 site Stand-aloneOther conditions: Healthy VolunteersView official trial listing → -
Completed NCT NCT07599293
Emulation of the EMPEROR-Preserved Trial Using Healthcare Claims Data
Brigham and Women's Hospital 39614 participants Est. completion 2026-06-19 1 siteHeart failureType 2 diabetesView official trial listing → -
Completed NCT NCT07599345
Emulation of the EMPEROR-Reduced Trial Using Healthcare Claims Data
Brigham and Women's Hospital 23955 participants Est. completion 2026-06-15 1 siteHeart failureView official trial listing → -
Not yet recruiting NCT NCT07675174
Phase I-II PTCy, Bortezomib and Sitagliptin for Prevention of GvHD Following Allogeneic HSCT
Not yet reported, Not yet reported Northwell Health 72 participants Est. completion 2032-07-01 1 site Stand-aloneOther conditions: GVHD - Graft-Versus-Host DiseaseView official trial listing → -
Completed NCT NCT07677865
GLP-1 Receptor Agonists and Alzheimer's Disease: A Multi-National Target Trial Emulation
West China Hospital 213891 participants Est. completion 2026-06-24 1 siteType 2 diabetes Other conditions: Alzheimer Disease, Obesity & OverweightView official trial listing → -
Completed NCT NCT07679711
Bioequivalence Study of Sitagliptin/Metformin Extended-Release Tablets in Healthy Subjects
Not yet reported The Affiliated Hospital of Qingdao University 76 participants Est. completion 2023-03-22 1 site Stand-aloneOther conditions: Healthy VolunteersView official trial listing → -
Completed NCT NCT07763899
Clinical Study to Determine Bioequivalence Between Two Oral Medications of Sitagliptin/Metformin in Prolonged-release Tablets With 50 mg/1000 mg in Healthy Subjects, Fast Study.
Not yet reported ADIUM 46 participants Est. completion 2025-11-30 1 site Stand-aloneOther conditions: BioequivalanceView official trial listing → -
Completed NCT NCT07763912
Clinical Study to Determine Bioequivalence Between Two Oral Medications of Sitagliptin/Metformin in Prolonged-release Tablets With 50 mg/1000 mg in Healthy Subjects, Fed Study.
Not yet reported ADIUM 46 participants Est. completion 2025-12-05 1 site Stand-aloneOther conditions: BioequivalenceView official trial listing → -
Completed NCT NCT07763951
Clinical Study to Determine Bioequivalence Between Two Oral Medications of Sitagliptin/Metformin in Prolonged-release Tablets With 100 mg/1000 mg in Healthy Subjects, Fast Study.
Not yet reported ADIUM 46 participants Est. completion 2025-12-14 1 site Stand-aloneOther conditions: BioequivalanceView official trial listing → -
Completed NCT NCT07763964
Clinical Study to Determine Bioequivalence Between Two Oral Medications of Sitagliptin/Metformin in Prolonged-release Tablets With 100 mg/1000 mg in Healthy Subjects, Fed Study.
Not yet reported ADIUM 46 participants Est. completion 2025-12-19 1 site Stand-aloneOther conditions: BioequivalanceView official trial listing → -
Not yet recruiting NCT NCT07804381
Disease-modifying Efficacy of Sitagliptin Therapy in Early-stage Parkinson's Disease
Not yet reported Yonsei University 160 participants Est. completion 2029-04-01 Stand-aloneOther conditions: Parkinson DiseaseView official trial listing →
Efficacy history
Not yet reported.
Safety
Not yet reported.
Sources
Also known as: Sitagliptin, Sitagliptin (Januvia)
Related On The Pen coverage
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This drug may be investigational and not yet approved for any use. Whether someone can join a clinical trial is determined only by that trial's own study team — On The Pen does not determine eligibility. Information here can change; always confirm current details on the official ClinicalTrials.gov listing or with the sponsor.
